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1. 发明申请

US20090054522A1 Hair Care Product 审中-公开
标题翻译：护发产品
公开(公告)号：US20090054522A1
公开(公告)日：2009-02-26
申请号：US11884750
申请日：2006-02-14
申请人： Jun Nojima , Yasuo Miyake , Nobuaki Ohto
发明人： Jun Nojima , Yasuo Miyake , Nobuaki Ohto
IPC分类号： A61K31/19 , A61P17/14
CPC分类号： A61K8/63 , A61K8/66 , A61K31/19 , A61K31/56 , A61K2800/782 , A61Q5/00 , A61Q5/02 , A61Q7/00
摘要： With an object of discovering a substance having a testosterone 5α-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and of providing a hair care product having this substance blended therein, and a hair growth tonic, a testosterone 5α-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance as an active ingredient thereof, a hair care product of the present invention is made to contain corosolic acid therein, and each of a hair growth tonic, a testosterone 5α-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter of the present invention is made to contain corosolic acid as an active ingredient thereof.
摘要翻译：本发明的目的是发现具有睾酮5α-还原酶抑制作用的物质，毛发乳头细胞生长促进作用，成纤维细胞生长因子-7生产促进作用，血管内皮生长因子生成促进作用或骨形态发生蛋白-2生产促进作用，以及提供其中混合有该物质的护发产品和毛发生长补品，睾酮5α-还原酶抑制剂，毛乳头细胞生长促进剂，成纤维细胞生长因子-7生产促进剂，血管内皮生长因子生产促进剂和各自具有该物质作为其活性成分的骨形态发生蛋白-2生产促进剂，本发明的护发产品在其中含有科罗索酸，并且每种毛发生长滋补剂，睾酮5α-还原酶抑制剂，毛乳头细胞生长促进剂，成纤维细胞生长因子-7生产促进剂，血管内皮将本发明的生长因子生成促进剂和骨形态发生蛋白-2生产促进剂作为活性成分含有科罗索酸。

2. 发明授权

US07910557B2 Hair care product 有权
标题翻译：护发产品
公开(公告)号：US07910557B2
公开(公告)日：2011-03-22
申请号：US12585674
申请日：2009-09-22
申请人： Jun Nojima , Yasuo Miyake , Nobuaki Ohto
发明人： Jun Nojima , Yasuo Miyake , Nobuaki Ohto
IPC分类号： A01N45/00
CPC分类号： A61K8/63 , A61K8/66 , A61K31/19 , A61K31/56 , A61K2800/782 , A61Q5/00 , A61Q5/02 , A61Q7/00
摘要： A substance having a testosterone 5α-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and a hair care product having this substance blended therein. A hair growth tonic, a testosterone 5α-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance, such as corosolic acid, as an active ingredient thereof.
摘要翻译：具有睾酮5α-还原酶抑制作用，毛发乳头细胞生长促进作用，成纤维细胞生长因子-7生产促进作用，血管内皮生长因子生成促进作用或骨形态发生蛋白-2生产促进作用的物质，以及其中混合有该物质的护发产品。毛发生长补品，睾酮5α还原酶抑制剂，毛发乳头细胞生长促进剂，成纤维细胞生长因子-7生产促进剂，血管内皮生长因子生成促进剂和各自具有该物质的骨形态发生蛋白-2生产促进剂，作为科罗索酸，作为其活性成分。

3. 发明申请

US20100048703A1 Hair care product 有权
标题翻译：护发产品
公开(公告)号：US20100048703A1
公开(公告)日：2010-02-25
申请号：US12585674
申请日：2009-09-22
申请人： Jun Nojima , Yasuo Miyake , Nobuaki Ohto
发明人： Jun Nojima , Yasuo Miyake , Nobuaki Ohto
IPC分类号： A61K31/19 , A61P17/00 , A61P17/14
CPC分类号： A61K8/63 , A61K8/66 , A61K31/19 , A61K31/56 , A61K2800/782 , A61Q5/00 , A61Q5/02 , A61Q7/00
摘要： A substance having a testosterone 5α-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and a hair care product having this substance blended therein. A hair growth tonic, a testosterone 5α-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance, such as corosolic acid, as an active ingredient thereof.
摘要翻译：具有睾酮5α-还原酶抑制作用，毛发乳头细胞生长促进作用，成纤维细胞生长因子-7生产促进作用，血管内皮生长因子生成促进作用或骨形态发生蛋白-2生产促进作用的物质，以及其中混合有该物质的护发产品。毛发生长补品，睾酮5α还原酶抑制剂，毛发乳头细胞生长促进剂，成纤维细胞生长因子-7生产促进剂，血管内皮生长因子生成促进剂和各自具有该物质的骨形态发生蛋白-2生产促进剂，作为科罗索酸，作为其活性成分。

4. 发明授权

US06503650B1 Fuel cell system 有权
标题翻译：燃料电池系统
公开(公告)号：US06503650B1
公开(公告)日：2003-01-07
申请号：US09607119
申请日：2000-06-29
申请人： Takashi Yasuo , Yasuo Miyake
发明人： Takashi Yasuo , Yasuo Miyake
IPC分类号： H01M804
CPC分类号： H01M8/04291 , H01M8/04156 , H01M8/2485
摘要： A fuel cell system, comprising: (A) a cell multilayer element that is formed by stacking unit cell structures in layers, a unit cell structure including: a cell that includes a cathode, an anode, and electrolyte sandwiched between the cathode and the anode an oxidant channel unit with a plurality of oxidant channels that cross the cathode and enable oxidant to be supplied to the cathode; and a fuel channel unit with a plurality of fuel channels that cross the anode and enables fuel to be supplied to the anode; (B) oxidant supplying means for supplying the oxidant to the oxidant channels; and (C) fuel supplying means for supplying the fuel to the fuel channels, wherein the oxidant supplying means includes first switching means for reversing a flow direction of the oxidant in at least one of the oxidant channels and/or the fuel supplying means includes second switching means for reversing a flow direction of the fuel in at least one of the fuel channels.
摘要翻译：一种燃料电池系统，包括：（A）通过层叠单元电池结构形成的电池多层元件，单元电池结构，包括：包含阴极，阳极和夹在所述阴极和所述阳极之间的电解质的电池具有多个氧化剂通道的氧化剂通道单元，所述氧化剂通道穿过阴极并使氧化剂能够供应到阴极; 以及具有多个燃料通道的燃料通道单元，所述多个燃料通道穿过所述阳极并且能够将燃料供应到所述阳极; （B）用于将氧化剂供给到氧化剂通道的氧化剂供给装置; 和（C）用于向燃料通道供应燃料的燃料供应装置，其中氧化剂供给装置包括用于反转至少一个氧化剂通道和/或燃料供给装置中的氧化剂的流动方向的第一切换装置，包括第二用于使至少一个燃料通道中的燃料的流动方向反转的切换装置。

5. 发明授权

US06365293B1 Fuel cell having water permeability adjustment capability 有权
标题翻译：具有透水性调节能力的燃料电池
公开(公告)号：US06365293B1
公开(公告)日：2002-04-02
申请号：US09599198
申请日：2000-06-22
申请人： Takahiro Isono , Yasuo Miyake , Akira Hamada , Minoru Kaneko , Kunihiro Nakato
发明人： Takahiro Isono , Yasuo Miyake , Akira Hamada , Minoru Kaneko , Kunihiro Nakato
IPC分类号： H01M810
CPC分类号： H01M8/04291 , H01M8/1007
摘要： The object of the present invention is to provide fuel cell including a cell that is formed by sandwiching solid polymer membrane between an anode and a cathode that generates electricity with stability and high performance by evenly moistening the solid polymer membrane. For this purpose, in a gas diffusion layer 24, which is positioned adjacent to a cathode catalyst layer 22, the content of fluororesin in an area on the side of the entrance for the oxidizer is set to be higher than in another area on the side of the exit so that the water repellency in the entrance side area is higher than in the exit side area. As a result, a water permeation suppressing part 24A, where the water permeability is relatively low, is formed in the area on the entrance side, while a water permeable part 24B, where the water permeability is relatively high, is formed in the area on the exit side.
摘要翻译：本发明的目的是提供一种燃料电池，其包括通过将固体聚合物膜夹在阳极和阴极之间而形成的电池，其通过均匀润湿固体聚合物膜而稳定且高性能地发电。为此，在与阴极催化剂层22相邻的气体扩散层24中，氧化剂入口侧的区域中的氟树脂的含量设定为高于侧面的其他区域使得入口侧区域中的防水性高于出口侧区域。结果，在入口侧的区域中形成透水性相对较低的透水抑制部24A，而在透水性相对较高的水分透过部24B形成在出口侧。

6. 发明授权

US06329094B1 Polymer electrolyte fuel cell showing stable and outstanding electric-power generating characteristics 有权
标题翻译：聚合物电解质燃料电池表现出稳定和突出的发电特性
公开(公告)号：US06329094B1
公开(公告)日：2001-12-11
申请号：US09423168
申请日：1999-11-03
申请人： Takashi Yasuo , Toru Nakaoka , Akira Hamada , Yasuo Miyake , Yasunori Yoshimoto , Mitsuo Karakane
发明人： Takashi Yasuo , Toru Nakaoka , Akira Hamada , Yasuo Miyake , Yasunori Yoshimoto , Mitsuo Karakane
IPC分类号： H01M200
CPC分类号： H01M8/04089 , H01M8/0228 , H01M8/0247 , H01M8/0258 , H01M8/026 , H01M8/0271 , H01M8/04029 , H01M8/04119 , H01M8/04231 , H01M8/04291 , H01M8/0662 , H01M8/1007 , H01M8/241 , H01M8/242 , H01M8/2483 , H01M2300/0082
摘要： A solid polymer fuel cell which can stably generate electric power for long, because the cell is enabled to uniformly supply a fuel gas to all anodes by means of extended flow passages which are extended from anode-side flow passages and formed on a anode-side plate on the downstream side of the ends of the anodes in the direction of fuel gas flow, a water absorbing means for nearly uniformly performing water absorption, water retention, and drainage on all channels provided at the ends of the extended flow passages, and a selective gas discharging means for discharging a gas more selectively than water on the upstream side of the water absorbing means. In addition, the power generation characteristics and service life of the fuel cell can be improved further, because the cell can maintain a solid polymer film in a moist state as a whole and can efficiently supply the fuel gas to all anodes by a means for distributing the fuel gas to the inlet sections of the anode-side flow passages and a means for distributing water from a water source to the inlet sections of the anode-side flow passages through holes having a prescribed form and leading to the inlet sections of the anode-side flow passages.
摘要翻译：能够长时间稳定地发电的固体高分子型燃料电池，由于能够通过从阳极侧流路延伸并形成在阳极侧的延长流路使所有阳极均匀地供给燃料气体，在燃料气体流动方向的阳极端部的下游侧设置有用于在延伸流路的端部设置的所有通道上几乎均匀地进行吸水，保水和排水的吸水装置，选择性气体排出装置，用于在吸水装置的上游侧比水更有选择地排放气体。另外，能够进一步提高燃料电池的发电特性和使用寿命，因为电池可以将固体聚合物膜整体保持在潮湿状态，并且可以通过分配装置有效地将燃料气体供应到所有阳极向阳极侧流路的入口部分的燃料气体和用于将水从水源分配到阳极侧流路的入口部分的装置，通过具有规定形式的通孔并通向阳极的入口部分侧流通道。

7. 发明授权

US5975963A Female terminal 失效
标题翻译：女性终端
公开(公告)号：US5975963A
公开(公告)日：1999-11-02
申请号：US91904
申请日：1998-06-26
申请人： Mitsutoshi Higuchi , Toshikazu Mizutani , Satoru Imaeda , Yasuo Miyake , Takehiko Niwa , Haruo Shimura
发明人： Mitsutoshi Higuchi , Toshikazu Mizutani , Satoru Imaeda , Yasuo Miyake , Takehiko Niwa , Haruo Shimura
IPC分类号： H05K1/18 , H01R4/02 , H01R12/55 , H01R12/58 , H01R13/11 , H01R13/115 , H01R11/22
CPC分类号： H01R4/028 , H01R12/58 , H01R13/11 , H01R13/113
摘要： A female terminal has a structure that does not allow molten solder to close a pipe section into which male terminal is inserted. Notched recessed sections (9) are oppositely formed at the lower ends of the side faces (3a and 3a) of a female terminal (1). The female terminal (1) is locked by horizontally opening locking legs (7) protruded from the rear surface of a printed wiring board (11) from an inserting hole (12). In such a state, the rear surface of the board is dipped in molten solder (21). When the board (11), is pulled up from the molten solder (12), the solder (21) closing the pipe section (2) in a bridge-like form is turned to droplets and drops from the recessed section (9), because the wettability of the pipe section (2) with the solder (21) is lowered and the adhesion is weakened due to the recessed sections (9). The remaining molten solder (21) attaches to the peripheral edge of the end of the pipe section (2) other than the recessed sections (9) due to the surface tension and solidifies.
摘要翻译： PCT No.PCT / JP96 / 03827 Sec。 371日期：1998年6月26日 102（e）日期1998年6月26日PCT 1996年12月24日PCT公布。出版物WO97 / 24910 日期1997年7月10日母端子具有不允许熔融焊料封闭插入阳端子的管段的结构。在凹形端子（1）的侧面（3a和3a）的下端形成有凹口的凹部（9）。通过从插入孔（12）水平打开从印刷电路板（11）的后表面突出的锁定腿（7），阴端子（1）被锁定。在这种状态下，将板的后表面浸入熔融焊料（21）中。当板（11）从熔融焊料（12）拉起时，将管状部分（2）以桥状形式封闭的焊料（21）从凹部（9）转向液滴和滴落，因为具有焊料（21）的管部（2）的润湿性降低，并且由于凹部（9）而导致的粘接力减弱。剩余的熔融焊料（21）由于表面张力而附着到除了凹部（9）之外的管部（2）的端部的周边边缘并固化。

8. 发明授权

US5624683A Sustained-release multi-granule tablet 失效
标题翻译：持续释放多颗粒片剂
公开(公告)号：US5624683A
公开(公告)日：1997-04-29
申请号：US192603
申请日：1994-02-07
申请人： Hidenobu Andoh , Sumio Watanabe , Yasuo Miyake
发明人： Hidenobu Andoh , Sumio Watanabe , Yasuo Miyake
IPC分类号： A61K9/20 , A61K9/22 , A61K9/26 , A61K31/551
CPC分类号： A61K9/2081 , A61K31/551 , Y10S514/96 , Y10S514/961 , Y10S514/965
摘要： A sustained-release multi-granule tablet is obtained by compressing sustained-release granules, which contains a basis, and a formulation adjuvant. Each of the granules has been coated in advance with a layer of the formulation adjuvant and/or a layer of a mixture of the formulation adjuvant and the basis. The tablet releases an active substance at a suitable velocity into the digestion tract, resulting in that the inbalance in the absorption of the drug in each patient and among individual patients is minimized to achieve maximum bioavailability.
摘要翻译：通过压缩含有基础的缓释颗粒和制剂佐剂获得缓释多颗粒片剂。预先将各颗粒剂用制剂佐剂层和/或制剂佐剂和基质的混合物层进行包衣。片剂以适当的速度将活性物质释放到消化道中，导致每个患者和个体患者中药物吸收的不平衡被最小化以达到最大生物利用度。

9. 发明授权

US5425943A Modified tPA-containing injection composition having increased solubility 失效
标题翻译：改进的含tPA的注射组合物具有增加的溶解度
公开(公告)号：US5425943A
公开(公告)日：1995-06-20
申请号：US900796
申请日：1992-06-22
申请人： Masahiro Kawahara , Yuichiro Hayashi , Naoki Asakawa , Sumio Watanabe , Yasuo Miyake
发明人： Masahiro Kawahara , Yuichiro Hayashi , Naoki Asakawa , Sumio Watanabe , Yasuo Miyake
IPC分类号： A61K38/46 , A61K9/08 , A61K38/49 , A61K47/00 , A61K47/18 , A61K38/48 , C12N9/50 , C12N9/64
CPC分类号： A61K9/0019 , A61K38/49 , A61K47/183
摘要： An injection composition comprises a pharmacologically effective amount of a modified tPA, 47.5 mM or more of an amino acid or a salt thereof and is improved in view of stability and solubility.
摘要翻译：注射组合物包含药理学上有效量的修饰的tPA，47.5mM或更多的氨基酸或其盐，并且从稳定性和溶解性的观点来看是有改进的。

10. 发明授权

US4806809A Rotary shaft coupling device 失效
标题翻译：旋转轴联轴器
公开(公告)号：US4806809A
公开(公告)日：1989-02-21
申请号：US59612
申请日：1987-06-08
申请人： Kazuhisa Kubota , Hisashi Hirose , Takao Sakakibara , Yasuo Miyake , Sinzi Mizutani
发明人： Kazuhisa Kubota , Hisashi Hirose , Takao Sakakibara , Yasuo Miyake , Sinzi Mizutani
IPC分类号： F16D1/10 , G01P1/04 , H02K7/00
CPC分类号： G01P1/04 , F16D1/10
摘要： A device for coupling two rotary shafts, wherein a guide member is used on the coupling end of a first shaft to guide a coupling protrusion on the coupling end of a second shaft into a V-shaped coupling recess on the first shaft. The guide member can be made of a resilient plastic, to provide a flexible and detachable coupling member and reduce abnormal wear of the rotary shaft.
摘要翻译：一种用于联接两个旋转轴的装置，其中在第一轴的联接端上使用引导构件，以将第二轴的联接端上的联接突起引导到第一轴上的V形联接凹部中。引导构件可以由弹性塑料制成，以提供柔性和可拆卸的联接构件并减少旋转轴的异常磨损。

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