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1. 发明授权

US5048457A Plasma/radiation assisted molecular beam epitaxy method and apparatus 失效
标题翻译：等离子体/辐射辅助分子束外延法和装置
公开(公告)号：US5048457A
公开(公告)日：1991-09-17
申请号：US531711
申请日：1990-05-31
申请人： Julius Hyman, Jr. , John R. Beattie , Jesse N. Matossian , Owen K. Wu , Juan F. Lam , Lawrence Anderson
发明人： Julius Hyman, Jr. , John R. Beattie , Jesse N. Matossian , Owen K. Wu , Juan F. Lam , Lawrence Anderson
IPC分类号： C30B23/02
CPC分类号： C30B23/02 , C30B29/48
摘要： A molecular beam epitaxy (MBE) growth method and apparatus is disclosed which achieves a significantly improved sticking coefficient for materials like Hg upon a substrate, and thus a higher efficiency. A highly ionized, low pressure plasma is formed consisting of a mixture of ions of one substance of a compound to be epitaxially grown, neutral particles of the substance and electrons, and also preferably both ionization and excitation radiation. The plasma is directed onto a substrate together with a flux of the other substance in the compound; the flux can be in the form of either a vapor, or a second plasma. Radiation assisted epitaxial growth for Hg compounds in which ionization and excitation radiation are formed from Hg vapor and used to assist epitaxial growth with neutral Hg particles is also described. The plasma is formed in a special discharge chamber having a hollow cathode with an emissive-mix-free cathode insert. The source is preferably a refractory metal such as rolled tantalum foil, which is substantially emissive-material-free and does not contaminate the plasma. Good results are obtained by allowing the plasma to simply diffuse out through an exit port in the discharge chamber, without special extraction assemblies required by prior ion thrusters. Hg sticking coefficients have been improved by a factor of 40 or more.
摘要翻译：公开了一种分子束外延（MBE）生长方法和装置，其实现了对衬底上的诸如Hg的材料的显着改善的粘附系数，并且因此具有更高的效率。形成高离子化的低压等离子体，其由外延生长的化合物的一种物质的离子和物质的中性粒子和电子的混合物组成，并且还优选电离和激发辐射。等离子体与化合物中另一种物质的助熔剂一起引导到基底上; 通量可以是蒸汽或第二等离子体的形式。还描述了汞化合物的辐射辅助外延生长，其中电离和激发辐射由Hg蒸气形成并用于辅助外延生长与中性Hg颗粒。等离子体形成在具有空心阴极的特殊放电室中，其具有无发射混合阴极插入物。来源优选是难熔金属，例如轧制钽箔，其基本上不发射材料，并且不污染等离子体。通过允许等离子体简单地通过放电室中的出口扩散出来，而不需要先前的离子推进器所需的特殊提取组件，可获得良好的结果。 Hg粘附系数提高了40倍以上。

2. 发明授权

US5152866A Plasma/radiation assisted molecular beam epitaxy method 失效
标题翻译：等离子/辐射辅助分子束外延法
公开(公告)号：US5152866A
公开(公告)日：1992-10-06
申请号：US532144
申请日：1990-05-31
申请人： Julius Hyman, Jr. , John R. Beattie , Jesse N. Matossian , Owen K. Wu , Juan F. Lam , Lawrence Anderson
发明人： Julius Hyman, Jr. , John R. Beattie , Jesse N. Matossian , Owen K. Wu , Juan F. Lam , Lawrence Anderson
IPC分类号： C30B23/02
CPC分类号： C30B23/02 , C30B29/48
摘要： A molecular beam epitaxy (MBE) growth method and apparatus is disclosed which achieves a significantly improved sticking coefficient for materials like Hg upon a substrate, and thus a higher efficiency. A highly ionized, low pressure plasma is formed consisting of a mixture of ions of one substance of a compound to be epitaxially grown, neutral particles of the substance and electrons, and also preferably both ionization and excitation radiation. The plasma is directed onto a substrate together with a flux of the other substance in the compound; the flux can be in the form of either a vapor, or a second plasma. Radiation assisted epitaxial growth for Hg compounds in which ionization and excitation radiation are formed from Hg vapor and used to assist epitaxial growth with neutral Hg particles is also described. The plasma is formed in a special discharge chamber having a hollow cathode with an emissive-mix-free cathode insert. The source is preferably a refractory metal such as rolled tantalum foil, which is substantially emissive-material-free and does not contaminate the plasma. Good results are obtained by allowing the plasma to simply diffuse out through an exit port in the discharge chamber, without special extraction assemblies required by prior ion thrusters. Hg sticking coefficients have been improved by a factor of 40 or more.
摘要翻译：公开了一种分子束外延（MBE）生长方法和装置，其实现了对衬底上的诸如Hg的材料的显着改善的粘附系数，并且因此具有更高的效率。形成高离子化的低压等离子体，其由外延生长的化合物的一种物质的离子和物质的中性粒子和电子的混合物组成，并且还优选电离和激发辐射。等离子体与化合物中另一种物质的助熔剂一起引导到基底上; 通量可以是蒸汽或第二等离子体的形式。还描述了汞化合物的辐射辅助外延生长，其中电离和激发辐射由Hg蒸气形成并用于辅助外延生长与中性Hg颗粒。等离子体形成在具有空心阴极的特殊放电室中，其具有无发射混合阴极插入物。来源优选是难熔金属，例如轧制钽箔，其基本上不发射材料，并且不污染等离子体。通过允许等离子体简单地通过放电室中的出口扩散出来，而不需要先前的离子推进器所需的特殊提取组件，可获得良好的结果。 Hg粘附系数提高了40倍以上。

3. 发明授权

US06683045B2 Nucleosides for imaging and treatment applications 失效
公开(公告)号：US06683045B2
公开(公告)日：2004-01-27
申请号：US09941571
申请日：2001-08-30
申请人： Raymond W. Klecker , Lawrence Anderson , Aspandiar G. Katki , Jerry M. Collins
发明人： Raymond W. Klecker , Lawrence Anderson , Aspandiar G. Katki , Jerry M. Collins
IPC分类号： A01N6100
CPC分类号： C07H21/00 , C07H19/06
摘要： Methods of diagnosing and/or of treating tumors by administering a nucleoside analogue which is activated by thymidylate synthase and/or thymidine kinase enzyme into a diagnostic or toxic metabolite, and uridine analogue compounds, and compositions of same having a pharmaceutically acceptable carrier. For diagnostic applications, compounds containing a label and methods of use of such compounds are described.

4. 发明申请

US20050042463A1 Multi-layer composites formed from compositions having improved adhesion, coating compositions, and methods related thereto 有权
标题翻译：由具有改进的粘附性，涂层组合物和与其相关的方法的组合物形成的多层复合材料
公开(公告)号：US20050042463A1
公开(公告)日：2005-02-24
申请号：US10935643
申请日：2004-09-07
申请人： Lawrence Anderson , John Burgman , Karen Morow , Richard Sadvary , Shiryn Tyebjee , Dennis Simpson , Thomas Hockswender
发明人： Lawrence Anderson , John Burgman , Karen Morow , Richard Sadvary , Shiryn Tyebjee , Dennis Simpson , Thomas Hockswender
IPC分类号： B32B27/18 , B05D7/00 , C08J5/12 , C08K3/38 , C08K5/06 , C08K5/55 , C08L83/04 , C08L83/05 , C09D7/12 , C09D133/00 , C09D167/00 , C09D171/00 , C09D175/04 , C09D183/00 , C09D183/05 , C09D183/06 , C09D183/07 , C09D183/08 , C09J11/00 , C09J183/05 , C09J183/06 , C09J183/07 , C09J183/08 , B32B27/30 , B32B27/36
CPC分类号： B05D7/57 , B05D7/574 , C08J5/12 , C08K3/38 , C08K5/55 , C09D7/60 , Y10T428/31511 , Y10T428/31663 , Y10T428/31725 , Y10T428/31786 , Y10T428/31935
摘要： The present invention provides an improved multi-layer composite of two or more polymeric layers at least one of which is formed from a thermosetting composition. The composite includes at least a first polymeric layer formed on a substrate and a second polymeric layer over the first polymeric layer, wherein in the absence of a boron-containing compound, the first and second polymeric layers have poor interlayer adhesion. The improvement resides in the inclusion of at least one boron-containing compound in one or both of the first and second polymeric layers in an amount sufficient to improve the interlayer adhesion between the first and second polymeric layers. Also provided is an improved curable coating composition used to form a multi-layer composite coating of two or more cured coating layers, at least one of which is formed from the thermosetting composition. Related methods and coated substrates are also provided.
摘要翻译：本发明提供了两种或更多种聚合物层的改进的多层复合材料，其中至少一种由热固性组合物形成。所述复合材料包括形成在基材上的至少第一聚合物层和在所述第一聚合物层上的第二聚合物层，其中在不存在含硼化合物的情况下，所述第一和第二聚合物层具有差的层间粘合性。改进在于在足以改善第一和第二聚合物层之间的层间粘合力的量中将至少一种含硼化合物包含在第一和第二聚合物层的一个或两个中。还提供了一种改进的可固化涂料组合物，其用于形成两层或多层固化涂层的多层复合涂层，其中至少一层由热固性组合物形成。还提供了相关方法和涂覆的基底。

5. 发明授权

US06753309B2 Nucleosides for imaging and treatment applications 失效
公开(公告)号：US06753309B2
公开(公告)日：2004-06-22
申请号：US10122173
申请日：2002-04-16
申请人： Raymond W. Klecker , Lawrence Anderson , Aspandiar G. Katki , Jerry M. Collins
发明人： Raymond W. Klecker , Lawrence Anderson , Aspandiar G. Katki , Jerry M. Collins
IPC分类号： A01N6100
CPC分类号： C07H21/00 , C07H19/06
摘要： Methods of diagnosing and/or of treating tumors by administering a nucleoside analogue which is activated by thymidylate synthase and/or thymidine kinase enzyme into a diagnostic or toxic metabolite, and uridine analogue compounds, and compositions of same having a pharmaceutically acceptable carrier. For diagnostic applications, compounds containing a label and methods of use of such compounds are described.

6. 发明申请

US20050249958A1 Film-forming compositions substantially free of organic solvent, multi-layer composite coatings and related methods 审中-公开
标题翻译：基本上不含有机溶剂的成膜组合物，多层复合涂层和相关方法
公开(公告)号：US20050249958A1
公开(公告)日：2005-11-10
申请号：US10841662
申请日：2004-05-07
申请人： Charles Kania , Roxalana Martin , Carolyn Novak , Thomas Hockswender , Mark Tucker , Mary Grolemund , Deirdre Ragan , Alicia Williams , Gina Terrago , Lawrence Anderson
发明人： Charles Kania , Roxalana Martin , Carolyn Novak , Thomas Hockswender , Mark Tucker , Mary Grolemund , Deirdre Ragan , Alicia Williams , Gina Terrago , Lawrence Anderson
IPC分类号： C08G18/28 , C08G18/70 , C09D175/04 , B05D3/02
CPC分类号： C08G18/283 , C08G18/706 , C09D175/04 , Y10T428/31551
摘要： Film-forming compositions are disclosed that are substantially free of organic solvent. The film-forming compositions include a resinous binder and at least one water dilutable additive including the reaction product of (i) a reactant including at least one isocyanate functional group with (ii) an active hydrogen containing alkoxypolyalkylene compound. Also disclosed are multi-layer composite coatings that include such film-forming compositions and methods of applying such multi-component composite coatings to a substrate.
摘要翻译：公开了基本上不含有机溶剂的成膜组合物。成膜组合物包括树脂粘合剂和至少一种水可稀释添加剂，其包括（i）包含至少一种异氰酸酯官能团的反应物与（ii）含活性氢的烷氧基聚亚烷基化合物的反应产物。还公开了包括这种成膜组合物和将这种多组分复合涂层施加到基底的方法的多层复合涂层。

7. 发明申请

US20050137267A1 Colloidal particle sols and methods for preparing the same 有权
标题翻译：胶体颗粒溶胶及其制备方法
公开(公告)号：US20050137267A1
公开(公告)日：2005-06-23
申请号：US11001543
申请日：2004-12-01
申请人： Lawrence Anderson , Debra Singer , Thomas Hockswender
发明人： Lawrence Anderson , Debra Singer , Thomas Hockswender
IPC分类号： B01D12/00 , B01J13/00 , C01B33/145 , C01B33/148 , B01F3/12
CPC分类号： C01B33/145 , B01J13/0008 , B01J13/0026 , C01B33/1485
摘要： A method of preparing an organic sol of particles is provided. Steps include: a) providing a suspension of particles in an aqueous medium; b) adding an organic liquid to form an admixture where the concentration of particles in the admixture is less than or equal to 40 percent by weight; c) maintaining the admixture at a temperature and pressure and for a time sufficient to reduce the water content to less than 30 percent by weight while simultaneously adding a water-compatible organic liquid at a rate sufficient to maintain a concentration of particles in the admixture at less than or equal to 50 percent by weight; and d) adding at least one polymer while maintaining the admixture at a temperature and pressure and for a time sufficient to provide an organic sol of particles comprising 1 percent by weight or less of water.
摘要翻译：提供了制备颗粒有机溶胶的方法。步骤包括：a）在水介质中提供颗粒的悬浮液; b）加入有机液体以形成其中混合物中颗粒的浓度小于或等于40重量％的混合物; c）将混合物在温度和压力下保持足够的时间以将水含量降低至小于30重量％，同时以足以将混合物中颗粒的浓度保持在混合物中的速率同时加入水相容性有机液体小于或等于50重量％; 和d）在保持混合物的温度和压力下加入至少一种聚合物，并持续足以提供包含1重量％或更少的水的颗粒的有机溶胶的时间。

8. 发明授权

US06677315B2 Nucleosides for imaging and treatment applications 失效
公开(公告)号：US06677315B2
公开(公告)日：2004-01-13
申请号：US09941551
申请日：2001-08-30
申请人： Raymond W. Klecker , Lawrence Anderson , Aspandiar G. Katki , Jerry M. Collins
发明人： Raymond W. Klecker , Lawrence Anderson , Aspandiar G. Katki , Jerry M. Collins
IPC分类号： A01N4304
CPC分类号： C07H21/00 , C07H19/06
摘要： Methods of diagnosing and/or of treating tumors by administering a nucleoside analogue which is activated by thymidylate synthase and/or thymidine kinase enzyme into a diagnostic or toxic metabolite, and uridine analogue compounds, and compositions of same having a pharmaceutically acceptable carrier. For diagnostic applications, compounds containing a label and methods of use of such compounds are described.

9. 发明申请

US20070270549A1 COMPOSITIONS COMPRISING THIOETHER-FUNCTIONAL OLIGOMERIC POLYTHIOLS 有权
标题翻译：包含功能性低聚异戊二烯的组合物
公开(公告)号：US20070270549A1
公开(公告)日：2007-11-22
申请号：US11744266
申请日：2007-05-04
申请人： Chester Szymanski , Lawrence Anderson , Gregory McCollum
发明人： Chester Szymanski , Lawrence Anderson , Gregory McCollum
IPC分类号： C08L81/00
CPC分类号： C08G18/3876 , C08G18/3234 , C08G18/324 , C08G18/722 , C08G18/755 , C08G18/758 , C08G18/765 , C08G75/045 , C08L81/02 , C09D175/04 , G02B1/041 , Y10T428/31551 , C08L2666/14 , C08L75/04 , C08L81/00
摘要： Sealant and potting formulations comprising a thioether-functional, oligomeric polythiol prepared by reacting together: (a) a compound having at least two thiol functional groups; and (b) a compound having triple bond functionality are disclosed.
摘要翻译：通过使一起反应制备的含硫醚官能的低聚多硫醇的密封剂和灌封制剂：（a）具有至少两个硫醇官能团的化合物; 和（b）具有三键官能度的化合物。

10. 发明授权

US06703374B1 Nucleosides for imaging and treatment applications 失效
标题翻译：用于成像和治疗应用的核苷
公开(公告)号：US06703374B1
公开(公告)日：2004-03-09
申请号：US09530276
申请日：2000-04-28
申请人： Raymond W. Klecker , Lawrence Anderson , Aspandiar G. Katki , Jerry M. Collins
发明人： Raymond W. Klecker , Lawrence Anderson , Aspandiar G. Katki , Jerry M. Collins
IPC分类号： A01N6100
CPC分类号： C07H21/00 , C07H19/06
摘要： Methods of diagnosing and/or of treating tumors by administering a nucleoside analogue which is activated by thymidylate synthase and/or thymidine kinase enzyme into a diagnostic or toxic metabolite, and uridine analogue compounds, and compositions of same having a pharmaceutically acceptable carrier. For diagnostic applications, compounds containing a label and methods of use of such compounds are described.
摘要翻译：通过将由胸苷酸合酶和/或胸苷激酶酶活化的核苷类似物施用于诊断或毒性代谢物，以及尿苷类似物化合物及其具有药学上可接受的载体的组合物来诊断和/或治疗肿瘤的方法。对于诊断应用，描述了含有标记的化合物和使用这些化合物的方法。

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