专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06409020B1 Child-resistant blister package 失效
标题翻译：防儿童泡罩包装
公开(公告)号：US06409020B1
公开(公告)日：2002-06-25
申请号：US09631578
申请日：2000-08-04
申请人： Julian B. Lo
发明人： Julian B. Lo
IPC分类号： B65D8304
CPC分类号： B65D83/0463
摘要： The invention provides a child-resistant apparatus for dispensing articles which comprises a housing for retaining a blister package wherein the, housing comprises a dispensing aperture; optionally, but preferably, a blister package comprising at least one blister cell containing an article to be dispensed; and a substantially rigid backing sheet substantially co-extensive with, and substantially blocking, the dispensing aperture wherein the backing sheet comprises exposed end portions, such that pressure applied on either exposed end portion individually, or on both exposed end portions simultaneously of the backing sheet, imparts arcuate flexure thereto and dislocation thereof from the substantially co-extensive, and substantially blocking position, to a position where the dispensing aperture is unblocked permitting the article contained in the blister cell to be dispensed. Release of pressure on the exposed end portion or portions of the backing sheet relaxes flexure thereof such that the substantially co-extensive, and substantially blocking position, wherein the backing sheet substantially blocks the dispensing aperture, is restored.
摘要翻译：本发明提供一种用于分配物品的防儿童装置，其包括用于保持泡罩包装的壳体，其中，壳体包括分配孔; 可选地，但优选地，包括包含至少一个含有待分配物品的泡罩细胞的泡罩包装; 以及基本上刚性的背衬片材，其基本上与所述分配孔口共同扩张并且基本上阻挡所述分配孔，其中所述背衬片材包括暴露的端部部分，使得分别施加在任一暴露端部上的压力，或同时施加在所述背衬片材的两个暴露端部上向其施加弓形弯曲并将其从基本上共同且基本上阻挡位置脱位到分配孔未被阻挡的位置，允许分配包含在泡罩单元中的制品。在暴露的端部或背衬片的部分上的压力释放使其弯曲松弛，使得基本上共同且基本上阻挡的位置（其中背衬片基本上阻挡分配孔）被恢复。

2. 发明授权

US06503222B2 Oral dosage dispenser 失效
公开(公告)号：US06503222B2
公开(公告)日：2003-01-07
申请号：US09960001
申请日：2001-09-21
申请人： Julian B. Lo
发明人： Julian B. Lo
IPC分类号： A61J700
CPC分类号： A61J7/0038 , A47G21/183 , Y10S215/03 , Y10S215/07 , Y10S215/08
摘要： The present invention provides an apparatus for facilitating the oral delivery of an active agent to a patient in need of treatment therewith, which apparatus comprises an active agent mixing chamber, a mixture delivery tube, and at least one liquid delivery tube. A mixture formed in the mixing chamber which comprises a combination of an active agent, or a pharmaceutical formulation thereof, and a liquid diluent may be delivered into the oral cavity of the patient from the mixing chamber by suction on the mixture delivery tube.

3. 外观设计

USD444056S1 Blister package dispenser 失效
标题翻译：吸塑包装机
公开(公告)号：USD444056S1
公开(公告)日：2001-06-26
申请号：US29117364
申请日：2000-01-21
申请人： Julian B. Lo
设计人： Julian B. Lo

4. 发明授权

US5516530A Porous shaped delivery devices and method of producing thereof 失效
标题翻译：多孔形输送装置及其制造方法
公开(公告)号：US5516530A
公开(公告)日：1996-05-14
申请号：US244700
申请日：1994-06-01
申请人： Julian B. Lo , Gary G. Mackay , Michael J. Puz
发明人： Julian B. Lo , Gary G. Mackay , Michael J. Puz
IPC分类号： A61J3/10 , A61K9/20 , A61K9/44
CPC分类号： A61K9/2095
摘要： High strength, high porosity delivery devices have a shaped surface and disintegrate quickly in an aqueous medium. The devices can be prepared by disposing a formulation in a die to form a frozen predevice. A second die is contacted with the frozen formulation surface at a pressure and temperature for a time sufficient to locally momentarily liquify and shape the device surface. The shaping is followed by lyophilization.
摘要翻译： PCT No.PCT / US92 / 09273 Sec。 371日期1994年6月1日 102（e）日期1994年6月1日PCT提交1992年11月4日PCT公布。出版物WO93 / 12770 PCT 日期：1993年7月8日。高强度，高孔隙率输送装置具有成形表面，并在水性介质中快速崩解。可以通过将制剂置于模具中以形成冷冻预装置来制备装置。在压力和温度下将第二模具与冷冻配方表面接触足以局部地瞬间液化和成形设备表面的时间。成型之后是冻干。

5. 发明授权

US08236328B2 Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers 有权
标题翻译：与聚合物混合的无定形药物的分散体的药物组合物
公开(公告)号：US08236328B2
公开(公告)日：2012-08-07
申请号：US12217700
申请日：2008-07-08
申请人： Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
发明人： Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
IPC分类号： A61K9/00 , A61K9/14
CPC分类号： A61K9/146
摘要： A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.
摘要翻译：药物组合物包含包含低溶解度药物和与浓度增强聚合物组合的基质的分散体。至少大部分药物在分散体中是无定形的。组合物改善药物在分散体中的稳定性和/或药物在使用环境中的浓度。

6. 发明授权

US06984403B2 Azithromycin dosage forms with reduced side effects 有权
标题翻译：阿奇霉素剂型具有减少的副作用
公开(公告)号：US06984403B2
公开(公告)日：2006-01-10
申请号：US10763340
申请日：2004-01-23
申请人： Timothy A. Hagen , Julian B. Lo , Avinash G. Thombre , Scott M. Herbig , Leah Elizabeth Appel , Marshall David Crew , Dwayne Thomas Friesen , David Keith Lyon , Scott Baldwin McCray , James Blair West
发明人： Timothy A. Hagen , Julian B. Lo , Avinash G. Thombre , Scott M. Herbig , Leah Elizabeth Appel , Marshall David Crew , Dwayne Thomas Friesen , David Keith Lyon , Scott Baldwin McCray , James Blair West
IPC分类号： A61K9/14
CPC分类号： A61K9/1611 , A61K9/143 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1641 , A61K9/1694 , A61K9/2009 , A61K9/2013 , A61K9/2031 , A61K31/7052
摘要： The present invention is related to an oral dosage form comprising an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a glyceride which comprises glyceryl monobehenate, glyceryl dibehenate, glyceryl tribehenate, or a mixture thereof and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule.
摘要翻译：本发明涉及包含有效量的碱化剂和阿奇霉素多颗粒的口服剂型，其中所述多颗粒包含阿奇霉素，其包含甘油单硬脂酸甘油酯，二苯乙酸甘油酯，枸橼酸甘油酯或其混合物和泊洛沙姆的甘油酯。通常，口服剂型包括任何合适的口服给药方式，例如用于口服悬浮液的粉末，单位剂量包或小药囊，片剂或胶囊。

7. 外观设计

USD392562S Blister pack 失效
公开(公告)号：USD392562S
公开(公告)日：1998-03-24
申请号：US61729
申请日：1996-10-29
申请人： Julian B. Lo
设计人： Julian B. Lo

8. 发明授权

US08703196B2 Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers 有权
标题翻译：与聚合物混合的无定形药物的分散体的药物组合物
公开(公告)号：US08703196B2
公开(公告)日：2014-04-22
申请号：US13563536
申请日：2012-07-31
申请人： Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
发明人： Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
IPC分类号： A61K9/14 , A61K47/38
CPC分类号： A61K9/146
摘要： A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.
摘要翻译：药物组合物包含包含低溶解度药物和与浓度增强聚合物组合的基质的分散体。至少大部分药物在分散体中是无定形的。组合物改善药物在分散体中的稳定性和/或药物在使用环境中的浓度。

9. 发明授权

US06401926B1 Child-resistant blister package 失效
标题翻译：防儿童泡罩包装
公开(公告)号：US06401926B1
公开(公告)日：2002-06-11
申请号：US09631577
申请日：2000-08-04
申请人： Julian B. Lo
发明人： Julian B. Lo
IPC分类号： B65D8304
CPC分类号： B65D83/0463 , B65D85/58 , B65D2215/04
摘要： A child-resistant apparatus for dispensing articles which comprises a housing for retaining a blister package wherein the housing comprises a dispensing aperture; optionally, but preferably, a blister package comprising at least one blister cell containing an article to be dispensed; and a substantially rigid backing sheet substantially co-extensive with, and substantially blocking, the dispensing aperture, such that pressure exerted on an exposed top edge of the backing sheet imparts arcuate flexure thereto and dislocation thereof from the substantially co-extensive, and substantially blocking position, to a position where the dispensing aperture is unblocked permitting the at least one article contained in the at least one blister cell to be dispensed. Release of pressure on the exposed top edge of the backing sheet relaxes flexure thereof such that the substantially co-extensive, and substantially blocking position, wherein the backing sheet substantially blocks the dispensing aperture, is restored.
摘要翻译：一种用于分配物品的防儿童装置，包括用于保持泡罩包装的壳体，其中所述壳体包括分配孔; 可选地，但优选地，包括包含至少一个含有待分配物品的泡罩细胞的泡罩包装; 以及基本上刚性的背衬片基本上与分配孔基本共同并且基本上阻塞，使得施加在背衬片的暴露的顶部边缘上的压力向其施加弓形弯曲并使其从基本上共同且基本上阻塞位置，其中分配孔未被阻挡的位置允许包含在至少一个泡罩单元中的至少一个物品被分配。释放背衬片的暴露的顶部边缘上的压力松弛其弯曲，使得基本上共同且基本上阻挡的位置（其中背衬片基本上阻挡分配孔）被恢复。

10. 发明授权

US5819967A Child-resistant, senior friendly container 失效
标题翻译：防儿童，高级容器
公开(公告)号：US5819967A
公开(公告)日：1998-10-13
申请号：US868384
申请日：1997-06-03
申请人： Julian B. Lo
发明人： Julian B. Lo
IPC分类号： B65D50/06 , B65D50/10
CPC分类号： B65D50/062
摘要： A child-resistant, elderly-accessible safety container designed for storage of potentially hazardous materials. The closure includes three major components: a rotatable member secured coaxially around the neck of the container and having at least one biasing member disposed along its upper surface, at least one resilient abutment member, extending outward from the neck and terminating in a tip end, and is capable of being distended or compressed by the biasing member, and a closure member having at least one closure member stop disposed along its inner surface. Turning the rotatable member in a predetermined direction causes the biasing member to contact and compress the abutment member tangentially in relation to the outer surface of the neck. Such compression interrupts contact of the tip end of the abutment member with the closure member stop allowing the closure member to be rotated in the opposite direction and removed from the container. Alternatively, turning the rotatable member in another predetermined direction causes the biasing member to contact and distend the abutment member tangentially in relation to the outer surface of the neck. Such distension reinforces contact of the tip end of the abutment member with the closure member stop and prevents the closure member from being rotated in the opposite direction and removed from the container.
摘要翻译：一种耐小孩，易老人的安全容器，用于储存潜在的有害物质。闭合件包括三个主要部件：可旋转构件，其同轴地围绕容器的颈部固定，并且具有沿着其上表面设置的至少一个偏置构件，至少一个从颈部向外延伸并终止于末端的弹性邻接构件，并且能够被偏置构件膨胀或压缩，并且具有至少一个闭合构件的封闭构件沿其内表面设置。将可旋转构件沿预定方向转动将导致偏置构件相对于颈部的外表面相切地接触并压缩抵接构件。这种压缩中断了邻接构件的末端与闭合构件止动件的接触，从而允许闭合构件沿相反方向旋转并从容器移除。或者，在另一预定方向上转动可旋转构件使得偏置构件相对于颈部的外表面相切地接触和延伸抵接构件。这种膨胀加强了邻接构件的末端与闭合构件止动件的接触，并且防止闭合构件沿相反方向旋转并从容器移除。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式