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1. 发明申请

US20130112941A1 SEMICONDUCTOR STRUCTURE HAVING NANOCRYSTALLINE CORE AND NANOCRYSTALLINE SHELL WITH INSULATOR COATING 审中-公开
标题翻译：具有纳米晶核和具有绝缘体涂层的纳米晶体壳的半导体结构
公开(公告)号：US20130112941A1
公开(公告)日：2013-05-09
申请号：US13485761
申请日：2012-05-31
申请人： Juanita Kurtin , Matthew J. Carillo , Steven Hughes , Brian Theobald , Colin Reese , Oun-Ho Park , Georgeta Masson
发明人： Juanita Kurtin , Matthew J. Carillo , Steven Hughes , Brian Theobald , Colin Reese , Oun-Ho Park , Georgeta Masson
IPC分类号： H01L33/06
CPC分类号： H01L33/06 , B01J13/02 , B82Y30/00 , B82Y40/00 , B82Y99/00 , C01B19/007 , C01P2002/84 , C01P2004/04 , C01P2004/10 , C01P2004/54 , C01P2004/64 , C01P2004/80 , C09K11/02 , C09K11/025 , C09K11/565 , C09K11/883 , H01L21/02422 , H01L21/02557 , H01L21/0256 , H01L21/02601 , H01L21/02628 , H01L33/002 , H01L33/005 , H01L33/04 , H01L33/502
摘要： Semiconductor structures having a nanocrystalline core and corresponding nanocrystalline shell and insulator coating are described. In an example, a semiconductor structure includes an anisotropic nanocrystalline core composed of a first semiconductor material and having an aspect ratio between, but not including, 1.0 and 2.0. The semiconductor structure also includes a nanocrystalline shell composed of a second, different, semiconductor material at least partially surrounding the anisotropic nanocrystalline core. An insulator layer encapsulates the nanocrystalline shell and anisotropic nanocrystalline core.
摘要翻译：描述了具有纳米晶核和对应的纳米晶体壳和绝缘体涂层的半导体结构。在一个示例中，半导体结构包括由第一半导体材料构成并且具有但不包括1.0和2.0之间的纵横比的各向异性纳米晶核。半导体结构还包括由至少部分地围绕各向异性纳米晶核的第二不同的半导体材料组成的纳米晶体壳。绝缘体层封装纳米晶体壳和各向异性纳米晶核。

2. 发明授权

US09159872B2 Semiconductor structure having nanocrystalline core and nanocrystalline shell 有权
标题翻译：具有纳米晶核和纳米晶壳的半导体结构
公开(公告)号：US09159872B2
公开(公告)日：2015-10-13
申请号：US13485756
申请日：2012-05-31
申请人： Juanita Kurtin , Matthew J. Carillo , Steven Hughes
发明人： Juanita Kurtin , Matthew J. Carillo , Steven Hughes
IPC分类号： H01L29/06 , H01L33/04 , H01L21/02 , H01L33/50 , C09K11/02 , C09K11/56 , C09K11/88 , C01B19/00 , H01L33/06 , B82Y30/00 , H01L33/00 , B01J13/02 , B82Y40/00 , B82Y99/00
CPC分类号： H01L33/06 , B01J13/02 , B82Y30/00 , B82Y40/00 , B82Y99/00 , C01B19/007 , C01P2002/84 , C01P2004/04 , C01P2004/10 , C01P2004/54 , C01P2004/64 , C01P2004/80 , C09K11/02 , C09K11/025 , C09K11/565 , C09K11/883 , H01L21/02422 , H01L21/02557 , H01L21/0256 , H01L21/02601 , H01L21/02628 , H01L33/005 , H01L33/04 , H01L33/502
摘要： Semiconductor structures having a nanocrystalline core and corresponding nanocrystalline shell are described. In an example, a semiconductor structure includes an anisotropic nanocrystalline core composed of a first semiconductor material and having an aspect ratio between, but not including, 1.0 and 2.0. The semiconductor structure also includes a nanocrystalline shell composed of a second, different, semiconductor material at least partially surrounding the anisotropic nanocrystalline core.
摘要翻译：描述了具有纳米晶核和对应的纳米晶体壳的半导体结构。在一个示例中，半导体结构包括由第一半导体材料构成并且具有但不包括1.0和2.0之间的纵横比的各向异性纳米晶核。半导体结构还包括由至少部分地围绕各向异性纳米晶核的第二不同的半导体材料组成的纳米晶体壳。

3. 发明申请

US20130112940A1 SEMICONDUCTOR STRUCTURE HAVING NANOCRYSTALLINE CORE AND NANOCRYSTALLINE SHELL 有权
标题翻译：具有纳米晶核和纳米晶体壳的半导体结构
公开(公告)号：US20130112940A1
公开(公告)日：2013-05-09
申请号：US13485756
申请日：2012-05-31
申请人： Juanita Kurtin , Matthew J. Carillo , Steven Hughes
发明人： Juanita Kurtin , Matthew J. Carillo , Steven Hughes
IPC分类号： H01L33/04 , H01L29/06 , H01L21/20 , B82Y40/00 , B82Y99/00
CPC分类号： H01L33/06 , B01J13/02 , B82Y30/00 , B82Y40/00 , B82Y99/00 , C01B19/007 , C01P2002/84 , C01P2004/04 , C01P2004/10 , C01P2004/54 , C01P2004/64 , C01P2004/80 , C09K11/02 , C09K11/025 , C09K11/565 , C09K11/883 , H01L21/02422 , H01L21/02557 , H01L21/0256 , H01L21/02601 , H01L21/02628 , H01L33/005 , H01L33/04 , H01L33/502
摘要： Semiconductor structures having a nanocrystalline core and corresponding nanocrystalline shell are described. In an example, a semiconductor structure includes an anisotropic nanocrystalline core composed of a first semiconductor material and having an aspect ratio between, but not including, 1.0 and 2.0. The semiconductor structure also includes a nanocrystalline shell composed of a second, different, semiconductor material at least partially surrounding the anisotropic nanocrystalline core.
摘要翻译：描述了具有纳米晶核和对应的纳米晶体壳的半导体结构。在一个示例中，半导体结构包括由第一半导体材料构成并且具有但不包括1.0和2.0之间的纵横比的各向异性纳米晶核。半导体结构还包括由至少部分地围绕各向异性纳米晶核的第二不同的半导体材料组成的纳米晶体壳。

4. 发明申请

US20070178063A1 METHODS OF TREATING CANCER USING IL-21 AND MONOCLONAL ANTIBODY THERAPY 审中-公开
标题翻译：使用IL-21和单克隆抗体治疗癌症治疗方法
公开(公告)号：US20070178063A1
公开(公告)日：2007-08-02
申请号：US11539511
申请日：2006-10-06
申请人： Wayne Kindsvogel , Steven Hughes , Richard Holly , Christopher Clegg , Donald Foster , Rebecca Johnson , Mark Heipel , Pallavur Sivakumar
发明人： Wayne Kindsvogel , Steven Hughes , Richard Holly , Christopher Clegg , Donald Foster , Rebecca Johnson , Mark Heipel , Pallavur Sivakumar
IPC分类号： A61K38/20 , A61K39/395
CPC分类号： C07K16/32 , A61K38/20 , A61K39/395 , A61K39/39558 , C07K16/2818 , C07K16/2896 , C07K2317/732 , A61K2300/00
摘要： Methods for treating cancer by co-administering a therapeutic monoclonal antibody with IL-21 are described. Exemplary monoclonal antibodies that can be used are rituximab, trastuzumab and anti-CTLA-4 antibodies. The enhanced antitumor of the combination therapy is particularly useful for patient populations that are recalcitrant to monoclonal therapy, relapse after treatment with monoclonal antibodies or where the enhanced IL-21 antitumor effect reduces toxicities associated with treatment using the monoclonal antibodies.
摘要翻译：描述了通过用IL-21共同施用治疗性单克隆抗体来治疗癌症的方法。可以使用的示例性单克隆抗体是利妥昔单抗，曲妥珠单抗和抗CTLA-4抗体。联合治疗的增强的抗肿瘤剂对于单克隆治疗顽固性，用单克隆抗体治疗后复发或增强的IL-21抗肿瘤作用降低与使用单克隆抗体治疗相关的毒性的患者群体特别有用。

5. 发明申请

US20070048266A1 METHODS OF TREATING CANCER USING IL-21 审中-公开
标题翻译：使用IL-21治疗癌症的方法
公开(公告)号：US20070048266A1
公开(公告)日：2007-03-01
申请号：US11548196
申请日：2006-10-10
申请人： Andrew Nelson , Steven Hughes , Richard Holly
发明人： Andrew Nelson , Steven Hughes , Richard Holly
IPC分类号： A61K38/20
CPC分类号： C07K14/54 , A61K38/193 , A61K38/20 , A61K38/2013 , A61K38/2026 , A61K38/2086 , A61K45/06 , C07K16/2878 , C07K2317/73 , Y02A50/463 , Y02A50/465 , Y02A50/475 , Y02A50/481
摘要： Methods for treating mammals with cancer using molecules that have an IL-21 functional activity are described. The molecules having IL-21 functional activities include polypeptides that have homology to the human IL-21 polypeptide sequence and proteins fused to a polypeptide with IL-21 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer therapeutics.
摘要翻译：描述了使用具有IL-21功能活性的分子治疗具有癌症的哺乳动物的方法。具有IL-21功能活性的分子包括与人IL-21多肽序列具有同源性的多肽和与具有IL-21功能活性的多肽融合的蛋白质。分子可以用作单一疗法或与其他已知的癌症治疗剂组合使用。

6. 发明申请

US20060019290A1 Identification of markers in esophageal cancer, colon cancer, head and neck cancer, and melanoma 有权
标题翻译：鉴定食管癌，结肠癌，头颈癌和黑色素瘤中的标志物
公开(公告)号：US20060019290A1
公开(公告)日：2006-01-26
申请号：US11178134
申请日：2005-07-08
申请人： Tony Godfrey , Liqiang Xi , Siva Raja , Steven Hughes , William Gooding
发明人： Tony Godfrey , Liqiang Xi , Siva Raja , Steven Hughes , William Gooding
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16
摘要： Methods for identifying expression of markers indicative of the presence of esophageal, a squamous cell cancer, a squamous cell cancer of the head and neck, colon cancer and melanoma are provided. Also provided are articles of manufacture useful in such methods and compositions containing primers and probes useful in such methods.
摘要翻译：提供了用于鉴定指示存在食管，鳞状细胞癌，头颈部鳞状细胞癌，结肠癌和黑素瘤的标志物的表达的方法。还提供了可用于这种方法的制品，和含有可用于这些方法的引物和探针的组合物。

7. 发明申请

US20050082144A1 High speed food product peeling or cleaning machine and method 审中-公开
标题翻译：高速食品剥皮或清洗机及方法
公开(公告)号：US20050082144A1
公开(公告)日：2005-04-21
申请号：US10964493
申请日：2004-10-13
申请人： Daniel Maupin , David Zittel , Steven Hughes
发明人： Daniel Maupin , David Zittel , Steven Hughes
IPC分类号： A23N7/02 , A23N7/00
CPC分类号： A23N12/023 , A23N7/02
摘要： An apparatus for peeling or cleaning food product that includes a plurality of rollers each coupled to a drive box, preferably a gear box, by a vibration dampening coupling that preferably is disposed exteriorly of one end of the roller and part of the frame of the machine that supports the roller. A drive that preferably is an electric motor is attached to the drive box such that a plurality of rollers is driven thereby. Such an arrangement enables rollers to be driven at speeds of 600 RPM and preferably 750 RPM or faster, which decreases processing time and increases capacity and throughput. In a method of operation, each roller is driven at a speed of 750 RPM or greater to peel or clean food product before being discharged from the machine. In one preferred method, the rollers are driven at speeds between 900 and 1200 RPM.
摘要翻译：一种用于剥离或清洁食品的设备，其包括多个辊，每个辊通过减振联接器耦合到驱动箱，优选地是齿轮箱，该减振联接件优选地设置在辊的一端的外部和机器的框架的一部分支撑辊子。优选地是电动机的驱动器附接到驱动箱，从而驱动多个辊。这样的布置使辊能够以600RPM，优选地为750RPM或更快的速度被驱动，这降低了处理时间并且增加了容量和产量。在操作方法中，每个辊以750RPM或更高的速度被驱动以在从机器排出之前剥离或清洁食品。在一种优选的方法中，辊以900和1200RPM之间的速度驱动。

8. 发明申请

US20070299247A1 HUMAN CYTOKINE RECEPTOR 有权
公开(公告)号：US20070299247A1
公开(公告)日：2007-12-27
申请号：US11829011
申请日：2007-07-26
申请人： Scott Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen , Steven Hughes
发明人： Scott Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen , Steven Hughes
IPC分类号： C07K14/715
CPC分类号： C07K14/715 , A61K38/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”

9. 发明申请

US20070048271A1 Methos of treating cancer using IL-21 审中-公开
标题翻译：使用IL-21治疗癌症的Methos
公开(公告)号：US20070048271A1
公开(公告)日：2007-03-01
申请号：US11548946
申请日：2006-10-12
申请人： Andrew Nelson , Steven Hughes , Richard Holly
发明人： Andrew Nelson , Steven Hughes , Richard Holly
IPC分类号： A61K38/20 , A61K38/21
CPC分类号： C07K14/54 , A61K38/193 , A61K38/20 , A61K38/2013 , A61K38/2026 , A61K38/2086 , A61K45/06 , C07K16/2878 , C07K2317/73 , Y02A50/463 , Y02A50/465 , Y02A50/475 , Y02A50/481
摘要： Methods for treating mammals with cancer using molecules that have an IL-21 functional activity are described. The molecules having IL-21 functional activities include polypeptides that have homology to the human IL-21 polypeptide sequence and proteins fused to a polypeptide with IL-21 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer therapeutics.
摘要翻译：描述了使用具有IL-21功能活性的分子治疗具有癌症的哺乳动物的方法。具有IL-21功能活性的分子包括与人IL-21多肽序列具有同源性的多肽和与具有IL-21功能活性的多肽融合的蛋白质。分子可以用作单一疗法或与其他已知的癌症治疗剂组合使用。

10. 发明申请

US20070048268A1 METHODS OF TREATING CANCER USING IL-21 审中-公开
公开(公告)号：US20070048268A1
公开(公告)日：2007-03-01
申请号：US11548567
申请日：2006-10-11
申请人： Andrew Nelson , Steven Hughes , Richard Holly
发明人： Andrew Nelson , Steven Hughes , Richard Holly
IPC分类号： A61K38/20 , A61K39/395
CPC分类号： C07K14/54 , A61K38/193 , A61K38/20 , A61K38/2013 , A61K38/2026 , A61K38/2086 , A61K45/06 , C07K16/2878 , C07K2317/73 , Y02A50/463 , Y02A50/465 , Y02A50/475 , Y02A50/481
摘要： Methods for treating mammals with cancer using molecules that have an IL-21 functional activity are described. The molecules having IL-21 functional activities include polypeptides that have homology to the human IL-21 polypeptide sequence and proteins fused to a polypeptide with IL-21 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer therapeutics.

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