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1. 发明授权

US06749628B1 Stent and catheter assembly and method for treating bifurcations 有权
标题翻译：支架和导管组装及治疗分叉的方法
公开(公告)号：US06749628B1
公开(公告)日：2004-06-15
申请号：US09861473
申请日：2001-05-17
申请人： Joseph R. Callol , Brian D. Brandt , Nazanine Matin , Hans F. Valencia , W. Stan Wilson , Steve Bigus , David Chi , Brenda Cho
发明人： Joseph R. Callol , Brian D. Brandt , Nazanine Matin , Hans F. Valencia , W. Stan Wilson , Steve Bigus , David Chi , Brenda Cho
IPC分类号： A61F206
CPC分类号： A61F2/856 , A61F2/852 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/91591 , A61F2250/0039 , A61F2250/006
摘要： The present invention provides for an improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The present invention includes a trap door stent design, a stent delivery catheter assembly, an apparatus for crimping the stent and the method for crimping the stent onto the catheter assembly, and the method for delivering and implanting the stent in a bifurcated vessel. More particularly, the invention relates to a stent having rings aligned along a common longitudinal axis and connected by links, where the stent has a proximal section, a distal section and a central section. The number of rings and the expanded diameter of the sections is varied to create a “trap door” capable of expanding to a slightly larger diameter than the proximal section and distal section of the stent. The stent is implanted at a bifurcation so that the proximal section and distal section are in the main vessel, and the central section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel.
摘要翻译：本发明提供了用于修复形成分叉的主血管和侧分支血管的改进的支架设计和支架输送导管组件。本发明包括捕获门支架设计，支架输送导管组件，用于卷曲支架的装置和用于将支架卷曲到导管组件上的方法，以及用于将支架输送和植入分叉容器中的方法。更具体地说，本发明涉及一种支架，其具有沿着共同的纵向轴线对齐并通过连接件连接的环，其中支架具有近端部分，远侧部分和中心部分。改变环的数量和扩大的直径以产生能够扩展到比支架的近端部分和远端部分稍大的直径的“诱捕门”。支架以分叉植入，使得近端部分和远端部分在主血管中，并且中心部分覆盖至侧支血管的开口的至少一部分。第二支架可以植入侧支血管并且邻接扩张的中心部分以提供主血管和侧支血管中的分叉区域的全面覆盖。

2. 发明授权

US06709440B2 Stent and catheter assembly and method for treating bifurcations 有权
公开(公告)号：US06709440B2
公开(公告)日：2004-03-23
申请号：US10192981
申请日：2002-07-11
申请人： Joseph R. Callol , Brian D. Brandt , Nazanine Matin , Hans F. Valencia , W. Stan Wilson
发明人： Joseph R. Callol , Brian D. Brandt , Nazanine Matin , Hans F. Valencia , W. Stan Wilson
IPC分类号： A61M2510
CPC分类号： A61F2/856 , A61F2/852 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/91591 , A61F2250/0039 , A61F2250/006
摘要： The present invention provides for an improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The present invention includes a trap door stent design, a stent delivery catheter assembly, an apparatus for crimping the stent and the method for crimping the stent onto the catheter assembly, and the method for delivering and implanting the stent in a bifurcated vessel. More particularly, the invention relates to a stent having rings aligned along a common longitudinal axis and connected by links, where the stent has a proximal section, a distal section and a central section. The number of rings and the expanded diameter of the sections is varied to create a “trap door” capable of expanding to a slightly larger diameter than the proximal section and distal section of the stent. The stent is implanted at a bifurcation so that the proximal section and distal section are in the main vessel, and the central section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel.

3. 发明授权

US06673107B1 Bifurcated stent and method of making 有权
标题翻译：分叉支架和制作方法
公开(公告)号：US06673107B1
公开(公告)日：2004-01-06
申请号：US09455592
申请日：1999-12-06
申请人： Brian D. Brandt , Joseph R. Callol , Hans F. Valencia
发明人： Brian D. Brandt , Joseph R. Callol , Hans F. Valencia
IPC分类号： A61F206
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2002/065 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2002/91591 , A61F2250/006
摘要： A Y-shaped stent, or bifurcated stent, for stenting bifurcated vessels consists of a first generally cylindrical distal branch defining a first flow path for fluid flow, and a second generally cylindrical distal branch defining a second flow path for fluid flow. The first and second distal branches are interconnected by one or more bending elements at a carina junction, each of the bending elements being flexible such that the first and second distal branches are capable of pivoting about the bending elements at the carina junction, thus defining an angle of varying degree. A generally cylindrical proximal branch defines a third flow path for fluid flow. The proximal branch is attached to the first and second distal branches proximate the carina junction such that the first and second distal branches and the proximal branch are in communication with each other.
摘要翻译：用于支架分叉血管的Y形支架或分叉支架由限定用于流体流动的第一流动路径的第一大致圆柱形远端分支和限定用于流体流动的第二流动路径的第二大致圆柱形远端分支组成。第一和第二远端分支通过一个或多个弯曲元件在卡连接处互连，每个弯曲元件是柔性的，使得第一和第二远端分支能够围绕卡连接处的弯曲元件枢转，从而限定一个不同程度的角度。大致圆柱形近端分支限定用于流体流动的第三流动路径。近端分支附接到靠近卡连接处的第一和第二远端分支，使得第一和第二远端分支和近端分支彼此连通。

4. 发明授权

US08337540B2 Stent for treating bifurcations and method of use 有权
标题翻译：用于治疗分叉和使用方法的支架
公开(公告)号：US08337540B2
公开(公告)日：2012-12-25
申请号：US10022996
申请日：2001-12-17
申请人： Joseph R. Callol , W. Stan Wilson
发明人： Joseph R. Callol , W. Stan Wilson
IPC分类号： A61F2/84
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/91591 , A61F2220/0041 , A61F2220/0058
摘要： An improved stent design and stent delivery catheter assembly for repairing a main vessel proximal to a side branch vessel and the opening to the side branch vessel forming a bifurcation. The stent is particularly useful in treating a bifurcation where plaque is present proximal to the side branch vessel but not distal to the side branch vessel. The present invention includes a trap door stent design, a stent delivery catheter assembly, and the method for delivering and implanting the stent in a bifurcated vessel. More particularly, the invention relates to a stent having rings aligned along a common longitudinal axis and connected by links. The stent has first rings that are implanted in the main vessel proximal to the bifurcation and one or more second rings forming a trap door section to appose the opening to the side branch vessel and the main vessel.
摘要翻译：改进的支架设计和支架输送导管组件，用于修复靠近侧分支血管的主血管和形成分叉的侧分支血管的开口。该支架特别可用于治疗斑块存在于侧分支血管附近而不是侧分支血管远端的分叉处。本发明包括陷阱门支架设计，支架输送导管组件以及用于在分叉血管中输送和植入支架的方法。更具体地说，本发明涉及一种支架，其具有沿着共同的纵向轴线对准并通过连杆连接的环。支架具有植入到主分支附近的主容器中的第一环和一个或多个第二环，形成捕获门部分以将开口装配到侧分支容器和主容器。

5. 发明授权

US07645409B2 Polymer link hybrid stent 有权
标题翻译：聚合物链路混合支架
公开(公告)号：US07645409B2
公开(公告)日：2010-01-12
申请号：US12245420
申请日：2008-10-03
申请人： Richard J. Saunders , Joseph R. Callol , James Hong
发明人： Richard J. Saunders , Joseph R. Callol , James Hong
IPC分类号： B29C45/14
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/072 , A61F2002/91533 , A61F2002/91575 , A61F2002/91591 , A61F2220/0025 , A61F2220/005 , A61F2230/0013 , A61F2250/0014 , A61L31/022 , A61L31/10 , A61L31/18
摘要： The present invention is directed to an expandable polymer link hybrid stent for implantation in a body lumen, such as a coronary artery along with a method of making the stent. The stent generally includes a series of metallic cylindrical rings longitudinally aligned on a common axis of the stent and interconnected by a series of polymeric links. The polymer links are formed by applying polymer layers between the rings and laser ablating the excess material. The polymeric material forming the polymeric links, provides longitudinal and flexural flexibility to the stent while maintaining sufficient column strength to space the cylindrical rings along the longitudinal axis. The metallic material forming the rings provides the necessary radial stiffness.
摘要翻译：本发明涉及一种用于植入体腔（例如冠状动脉）的可扩张聚合物链路混合支架以及制造支架的方法。该支架通常包括一系列金属圆柱形环，其纵向对准在支架的公共轴线上并通过一系列聚合物连接件相互连接。通过在环之间施加聚合物层并激光烧蚀多余的材料来形成聚合物连接。形成聚合物链节的聚合物材料为支架提供纵向和弯曲的柔性，同时保持足够的柱强度以使圆柱形环沿着纵向轴线空间。形成环的金属材料提供必要的径向刚度。

6. 发明授权

US06916409B1 Apparatus and process for electrolytic removal of material from a medical device 失效
标题翻译：从医疗器械电解去除材料的装置和方法
公开(公告)号：US06916409B1
公开(公告)日：2005-07-12
申请号：US10335549
申请日：2002-12-31
申请人： Joseph R. Callol , Karim Said Osman , Napoleon L. Caliguiran , Rommel C. Lumauig
发明人： Joseph R. Callol , Karim Said Osman , Napoleon L. Caliguiran , Rommel C. Lumauig
IPC分类号： B23H3/00 , C25F3/14 , C25F7/00
CPC分类号： C25F3/14 , C25F7/00
摘要： An apparatus and process is disclosed for the electrolytic removal of metal from a device, such as a medical device. More particularly, the apparatus of the invention includes a mandrel having slots or openings therein to expose portions of a metallic device, such as a stent, to an electrolytic solution to remove metal from the exposed portion.
摘要翻译：公开了用于从诸如医疗装置的装置电解去除金属的装置和方法。更具体地，本发明的装置包括其中具有槽或开口的心轴，以将金属装置（例如支架）的部分暴露于电解液以从暴露部分移除金属。

7. 发明授权

US06585757B1 Endovascular stent with radiopaque spine 有权
标题翻译：血管内支架与不透射线的脊柱
公开(公告)号：US06585757B1
公开(公告)日：2003-07-01
申请号：US09396543
申请日：1999-09-15
申请人： Joseph R. Callol
发明人： Joseph R. Callol
IPC分类号： A61F206
CPC分类号： A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91533 , A61F2002/91575 , A61F2230/0013 , A61F2250/0098
摘要： A stent is formed from a series of radially aligned expandable rings. The rings are formed of a radio-transparent material that are linked by a radiopaque spine. A thin but very bright fluoroscopic image is thereby created, without compromising the strength of the stent. The small cross-section of the illuminated spine also serves to minimize interference with the image of the lesion when the stent is being positioned thereover. In the event galvanic corrosion causes the radiopaque spine to become detached from the radio-transparent ring elements, their expanded state precludes their shifting within the lumen. While the sandwiched position of the spine against the lumen wall prevents it from shifting as well.
摘要翻译：支架由一系列径向对准的可扩张环形成。环由无线电透明材料形成，其通过不透射线的脊柱连接。由此产生薄但非常明亮的透视图像，而不损害支架的强度。当支架被放置在其上时，照明脊柱的小横截面还用于最小化对病变图像的干扰。在电弧腐蚀的情况下，不透射线的脊柱从无线电透明环形元件脱离，它们的膨胀状态阻止它们在管腔内移动。虽然脊柱相对于管腔壁的夹持位置也防止其移动。

8. 发明授权

US06464723B1 Radiopaque stents 有权
标题翻译：不透射线支架
公开(公告)号：US06464723B1
公开(公告)日：2002-10-15
申请号：US09298263
申请日：1999-04-22
申请人： Joseph R. Callol
发明人： Joseph R. Callol
IPC分类号： A61F206
CPC分类号： A61F2/91 , A61B90/39 , A61F2/915 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2220/005 , A61F2220/0058 , A61F2230/0013 , A61F2250/0032 , A61F2250/0098 , A61L31/18
摘要： A stent is formed from a series of linked, radially aligned expandable rings. The end rings are formed of a radiopaque material while the rings positioned between the end rings are formed of a radio-transparent material. Two very bright fluoroscopic images are created by the end rings, without any compromise in the strength of the stent, while the center of the stent remains transparent so as not to obscure the image of lesion area when the stent is being centered therein.
摘要翻译：支架由一系列连接的径向对准的可扩张环形成。端环由不透射线材料形成，而位于端环之间的环由透射材料形成。通过端环产生两个非常明亮的透视图像，而在支架的强度方面没有任何妥协，而支架的中心保持透明，以便当支架居中时不会使病变区域的图像模糊。

9. 发明申请

US20110009948A1 Fiber Reinforced Composite Stents 有权
标题翻译：纤维增强复合支架
公开(公告)号：US20110009948A1
公开(公告)日：2011-01-13
申请号：US12878937
申请日：2010-09-09
申请人： Bin Huang , David C. Gale , Srinivasan Sridharan , Joseph R. Callol , Klaus Kleine , Syed F. A. Hossainy , Timothy A. Limon , Anthony J. Abbate
发明人： Bin Huang , David C. Gale , Srinivasan Sridharan , Joseph R. Callol , Klaus Kleine , Syed F. A. Hossainy , Timothy A. Limon , Anthony J. Abbate
IPC分类号： A61F2/82 , B05D1/02
CPC分类号： A61F2/915 , A61F2/04 , A61F2/06 , A61F2/90 , A61F2/91 , A61F2002/072 , A61F2002/91508 , A61F2002/91575 , A61F2210/0004 , A61F2210/0009 , A61F2210/0076 , A61F2220/005 , A61F2230/0013 , A61F2250/0098 , A61L31/129 , B23K26/402 , B23K26/50 , B23K2103/42 , B23K2103/50 , B29C43/02 , B29C45/0001 , B29C45/0005 , B29C45/0055 , B29C47/0004 , B29C47/0023 , B29C47/0026 , B29C47/0066 , B29C47/06 , B29C47/1045 , B29C53/566 , B29C53/583 , B29C59/02 , B29C59/021 , B29C2043/028 , B29K2101/00 , B29K2105/12 , B29K2267/043 , B29K2995/0056 , B29K2995/006 , B29L2023/003 , B29L2031/7546 , D03D3/02
摘要： Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.
摘要翻译：公开了用纤维增强的用于植入体腔的聚合复合支架。

10. 发明授权

US07771581B2 Apparatus and process for electrolytic removal of material from a medical device 有权
标题翻译：从医疗器械电解去除材料的装置和方法
公开(公告)号：US07771581B2
公开(公告)日：2010-08-10
申请号：US11132053
申请日：2005-05-17
申请人： Joseph R. Callol , Karim Said Osman , Napoleon L. Caliguiran , Rommel C. Lumauig
发明人： Joseph R. Callol , Karim Said Osman , Napoleon L. Caliguiran , Rommel C. Lumauig
IPC分类号： C25F3/02
CPC分类号： C25F3/14 , C25F7/00
摘要： An apparatus and process is disclosed for the electrolytic removal of metal from a device, such as a medical device. More particularly, the apparatus of the invention includes a mandrel having slots or openings therein to expose portions of a metallic device, such as a stent, to an electrolytic solution to remove metal from the exposed portion.
摘要翻译：公开了用于从诸如医疗装置的装置电解去除金属的装置和方法。更具体地，本发明的装置包括其中具有槽或开口的心轴，以将金属装置（例如支架）的部分暴露于电解液以从暴露部分移除金属。

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