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1. 发明申请

US20050006239A1 Solution phase electrophoresis device, components, and methods 有权
标题翻译：溶液相电泳装置，组分和方法
公开(公告)号：US20050006239A1
公开(公告)日：2005-01-13
申请号：US10843526
申请日：2004-05-10
申请人： Joseph Amshey , Timothy Updyke , Thomas Jackson , Michael Thacker
发明人： Joseph Amshey , Timothy Updyke , Thomas Jackson , Michael Thacker
IPC分类号： B01D61/58 , C07K1/26 , G01L1/20 , G01N27/447
CPC分类号： G01N27/44795 , G01N27/44704
摘要： A device for fluid phase electrophoresis, particularly solution phase isoelectric focusing, components thereof, and methods for use are presented.
摘要翻译：提出了一种用于流相相电泳的装置，特别是溶液相等电聚焦，其组分和使用方法。

2. 发明申请

US20050023141A1 Solution phase electrophoresis device, components, and methods 有权
公开(公告)号：US20050023141A1
公开(公告)日：2005-02-03
申请号：US10895427
申请日：2003-05-09
申请人： Joseph Amshey , Timothy Updyke , Thomas Jackson , Michael Thacker
发明人： Joseph Amshey , Timothy Updyke , Thomas Jackson , Michael Thacker
IPC分类号： B01D61/42 , C25B9/00 , G01N27/447 , G01R1/00
CPC分类号： B01D61/42 , G01N27/44795
摘要： A device for fluid phase electrophoresis, particularly solution phase isoelectric focusing, components thereof, and methods for use are presented.

3. 发明授权

US08404198B2 Apparatus for and method of processing biological samples 有权
标题翻译：生物样品处理装置及其处理方法
公开(公告)号：US08404198B2
公开(公告)日：2013-03-26
申请号：US12549311
申请日：2009-08-27
申请人： Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Korneija Zgonc
发明人： Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Korneija Zgonc
IPC分类号： B01L9/00
CPC分类号： B01L3/502715 , B01L3/50273 , B01L7/00 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0689 , B01L2200/10 , B01L2200/16 , B01L2300/0636 , B01L2300/0681 , B01L2300/0867 , B01L2300/088 , B01L2300/123 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655 , G01N2035/00306 , G01N2035/1037 , Y10T436/2575
摘要： The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
摘要翻译：本发明提供了用于自动化生物处理的系统，装置，装置和方法。适用于本发明的方案和生物处理方法的实例包括但不限于：免疫沉淀，染色质免疫沉淀，重组蛋白分离，核酸分离和分离，蛋白标记，分离和分离，细胞分离和分离，食品安全分析和自动珠基分离。在一些实施方案中，本发明提供自动化系统，自动化装置，自动化盒和western印迹处理的自动化方法。其他实施方案包括自动化系统，自动化装置，自动化盒和用于分离，制备和纯化核酸例如DNA或RNA或其片段的自动化方法，包括质粒DNA，基因组DNA，细菌DNA，病毒DNA和任何其它DNA，以及用于自动化系统，自动化设备，自动化盒和用于处理，分离和纯化蛋白质，肽等的自动化盒和自动化方法。

4. 发明授权

US08845984B2 Apparatus for and method of processing biological samples 有权
标题翻译：生物样品处理装置及其处理方法
公开(公告)号：US08845984B2
公开(公告)日：2014-09-30
申请号：US13615500
申请日：2012-09-13
申请人： Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Kornelija Zgonc
发明人： Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Kornelija Zgonc
IPC分类号： B01L9/00 , B01L3/00 , B01L7/00 , G01N35/00 , G01N35/10
CPC分类号： B01L3/502715 , B01L3/50273 , B01L7/00 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0689 , B01L2200/10 , B01L2200/16 , B01L2300/0636 , B01L2300/0681 , B01L2300/0867 , B01L2300/088 , B01L2300/123 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655 , G01N2035/00306 , G01N2035/1037 , Y10T436/2575
摘要： The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
摘要翻译：本发明提供了用于自动化生物处理的系统，装置，装置和方法。适用于本发明的方案和生物处理方法的实例包括但不限于：免疫沉淀，染色质免疫沉淀，重组蛋白分离，核酸分离和分离，蛋白标记，分离和分离，细胞分离和分离，食品安全分析和自动珠基分离。在一些实施方案中，本发明提供自动化系统，自动化装置，自动化盒和western印迹处理的自动化方法。其他实施方案包括自动化系统，自动化装置，自动化盒和用于分离，制备和纯化核酸例如DNA或RNA或其片段的自动化方法，包括质粒DNA，基因组DNA，细菌DNA，病毒DNA和任何其它DNA，以及用于自动化系统，自动化设备，自动化盒和用于处理，分离和纯化蛋白质，肽等的自动化盒和自动化方法。

5. 发明申请

US20100120129A1 APPARATUS FOR AND METHOD OF PROCESSING BIOLOGICAL SAMPLES 有权
标题翻译：装置和处理生物样品的方法
公开(公告)号：US20100120129A1
公开(公告)日：2010-05-13
申请号：US12549311
申请日：2009-08-27
申请人： Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Kornelija Zgonc
发明人： Joseph Amshey , Daniel Bezdek , Espir Kahatt , Alexander Khorlin , Lance Parsons , Todd Peterson , Timothy Powers , Michael Thacker , Timothy Updyke , Kornelija Zgonc
IPC分类号： G01N27/26 , C12M1/00 , C12N1/06
CPC分类号： B01L3/502715 , B01L3/50273 , B01L7/00 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0689 , B01L2200/10 , B01L2200/16 , B01L2300/0636 , B01L2300/0681 , B01L2300/0867 , B01L2300/088 , B01L2300/123 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655 , G01N2035/00306 , G01N2035/1037 , Y10T436/2575
摘要： The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
摘要翻译：本发明提供了用于自动化生物处理的系统，装置，装置和方法。适用于本发明的方案和生物处理方法的实例包括但不限于：免疫沉淀，染色质免疫沉淀，重组蛋白分离，核酸分离和分离，蛋白标记，分离和分离，细胞分离和分离，食品安全分析和自动珠基分离。在一些实施方案中，本发明提供自动化系统，自动化装置，自动化盒和western印迹处理的自动化方法。其他实施方案包括自动化系统，自动化装置，自动化盒和用于分离，制备和纯化核酸例如DNA或RNA或其片段的自动化方法，包括质粒DNA，基因组DNA，细菌DNA，病毒DNA和任何其它DNA，以及用于自动化系统，自动化设备，自动化盒和用于处理，分离和纯化蛋白质，肽等的自动化盒和自动化方法。

6. 发明申请

US20050121325A1 Composite compositions for electrophoresis 审中-公开
标题翻译：电泳用复合组合物
公开(公告)号：US20050121325A1
公开(公告)日：2005-06-09
申请号：US10946472
申请日：2004-09-20
申请人： Timothy Updyke , Ilana Margalit , Michael Thacker
发明人： Timothy Updyke , Ilana Margalit , Michael Thacker
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/44747 , G01N27/44739
摘要： The invention is drawn to composite agarose/acrylamide compositions and gels. In particular it relates to gels for the separation of molecules, particularly macromolecules such as proteins. The invention is also directed to the preparation of composite gels, the separation of molecules by techniques such as electrophoresis using such gels, and the transfer of proteins from such gels to a transfer membrane using an immunoblot transfer gel.
摘要翻译：本发明涉及复合琼脂糖/丙烯酰胺组合物和凝胶。特别地，它涉及用于分离分子的凝胶，特别是大分子如蛋白质。本发明还涉及复合凝胶的制备，通过诸如使用这种凝胶的电泳的技术分离分子，以及使用免疫印迹转移凝胶将蛋白从这种凝胶转移到转移膜。

7. 发明申请

US20130008790A1 COMPOSITE COMPOSITIONS FOR ELECTROPHORESIS 审中-公开
标题翻译：电泳用复合组合物
公开(公告)号：US20130008790A1
公开(公告)日：2013-01-10
申请号：US13490387
申请日：2012-06-06
申请人： Timothy Updyke , Ilana Margalit , Michael Thacker
发明人： Timothy Updyke , Ilana Margalit , Michael Thacker
IPC分类号： B01D57/02 , C07K1/26
CPC分类号： G01N27/44747 , G01N27/44739
摘要： The invention is drawn to composite agarose/acrylamide compositions and gels. In particular it relates to gels for the separation of molecules, particularly macromolecules such as proteins. The invention is also directed to the preparation of composite gels, the separation of molecules by techniques such as electrophoresis using such gels, and the transfer of proteins from such gels to a transfer membrane using an immunoblot transfer gel.
摘要翻译：本发明涉及复合琼脂糖/丙烯酰胺组合物和凝胶。特别地，它涉及用于分离分子的凝胶，特别是大分子如蛋白质。本发明还涉及复合凝胶的制备，通过诸如使用这种凝胶的电泳的技术分离分子，以及使用免疫印迹转移凝胶将蛋白从这种凝胶转移到转移膜。

8. 发明授权

US07622028B2 Solution phase electrophoresis device, components, and methods 有权
标题翻译：溶液相电泳装置，组分和方法
公开(公告)号：US07622028B2
公开(公告)日：2009-11-24
申请号：US10895427
申请日：2003-05-09
申请人： Joseph W. Amshey , Timothy V. Updyke , Thomas R. Jackson , Michael Thacker
发明人： Joseph W. Amshey , Timothy V. Updyke , Thomas R. Jackson , Michael Thacker
IPC分类号： G01N27/00 , B01D61/00
CPC分类号： B01D61/42 , G01N27/44795
摘要： A device for fluid phase electrophoresis, particularly solution phase isoelectric focusing, components thereof, and methods for use are presented.
摘要翻译：提出了一种用于流相相电泳的装置，特别是溶液相等电聚焦，其组分和使用方法。

9. 发明授权

US07850835B2 Solution phase electrophoresis device, components, and methods 有权
标题翻译：溶液相电泳装置，组分和方法
公开(公告)号：US07850835B2
公开(公告)日：2010-12-14
申请号：US10843526
申请日：2004-05-10
申请人： Joseph W. Amshey , Timothy V. Updyke , Thomas R. Jackson , Michael Thacker
发明人： Joseph W. Amshey , Timothy V. Updyke , Thomas R. Jackson , Michael Thacker
IPC分类号： G01N27/00 , B01D61/00
CPC分类号： G01N27/44795 , G01N27/44704
摘要： A device for fluid phase electrophoresis, particularly solution phase isoelectric focusing, components thereof, and methods for use are presented.
摘要翻译：提出了一种用于流相相电泳的装置，特别是溶液相等电聚焦，其组分和使用方法。

10. 发明授权

US07302839B1 Method and system for gathering pressure signature data using a scaled model in a wind tunnel 有权
标题翻译：在风洞中使用缩放模型收集压力特征数据的方法和系统
公开(公告)号：US07302839B1
公开(公告)日：2007-12-04
申请号：US11425909
申请日：2006-06-22
申请人： John Felter , Michael Thacker , Kelly Laflin
发明人： John Felter , Michael Thacker , Kelly Laflin
IPC分类号： G01M9/00
CPC分类号： G01M9/04
摘要： Disclosed is a method of and system for gathering off-body pressure signature data from a scaled model in a wind tunnel. The data is gathered using a probe having multiple longitudinally disposed static pressure ports. Because of the number of ports and their spacing, the probe is able to remain stationary in the tunnel for the entire range of Mach numbers and model positions to be tested. Thus, tunnel flow characteristics can be easily and effectively removed. The system also has an automated model positioning system which enables settings at different pitch, yaw, and roll angles. This enables the user to locate the model so that it can be traversed at a fixed distance above the probe while maintaining the desired angular orientation of the model. By repeatedly traversing the model at different angular orientations, a detailed and accurate off-body pressure distribution can be obtained. The wind tunnel test technique captures full off-body pressure signatures in a complete 360 degree azimuthal range.
摘要翻译：公开了一种用于从风洞中的缩放模型收集体外压力特征数据的方法和系统。使用具有多个纵向设置的静压端口的探针收集数据。由于端口数量及其间距，探头能够在要测试的马赫数和模型位置的整个范围内在隧道中保持静止。因此，可以容易且有效地去除隧道流动特性。该系统还具有自动化的模型定位系统，可以在不同的俯仰，偏航和滚动角度进行设置。这使得用户能够定位模型，使得其可以在保持模型的期望的角度定向的同时在探头上方固定的距离处穿过。通过以不同的角度方向重复地穿过模型，可以获得详细且准确的离体压力分布。风洞测试技术在完整的360度方位角范围内捕获完整的体外压力特征。

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