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1. 发明申请

US20210045876A1 Self-Adjusting Device 有权
公开(公告)号：US20210045876A1
公开(公告)日：2021-02-18
申请号：US16964974
申请日：2019-01-25
申请人： Jonh MACMAHON , Evan ANDERSON , Greg C. LIU , Chine, LLC
发明人： John MacMahon , Evan Anderson , Greg C. Liu
IPC分类号： A61F2/24
摘要： A self-adjusting device configured to be placed in contact with tissue/organ and apply mechanical force to the tissue/organ to achieve an improvement of functioning of the tissue/organ. The self-adjusting capabilities can be carried out by three functional subsystems that can be packaged either in a single, integrated system or in separate modules. A sensing subsystem senses the tissue/organ and sends at least one type of sensing signal characteristic of functioning of the tissue/organ to a controlling subsystem. The controlling subsystem processes the signal with an algorithm to determine if a configuration of the device needs to be changed or a force applied to the tissue/organ needs to be changed. An actuating subsystem can be controlled by the controlling subsystem to affect the configuration/force change when needed. A feedback loop is provided to keep the controlling subsystem up to date as to the state of the actuating subsystem.

2. 发明授权

US11833049B2 Self-adjusting device 有权
公开(公告)号：US11833049B2
公开(公告)日：2023-12-05
申请号：US16964974
申请日：2019-01-25
申请人： Chine, LLC , John MacMahon , Evan Anderson , Greg C. Liu
发明人： John MacMahon , Evan Anderson , Greg C. Liu
IPC分类号： A61F2/24 , A61B17/10 , A61B90/00 , A61B17/068 , A61B17/00 , A61B17/28 , A61B17/064
CPC分类号： A61F2/2481 , A61B17/068 , A61B17/10 , A61B90/06 , A61F2/246 , A61F2/2442 , A61F2/2451 , A61F2/2466 , A61F2/2478 , A61B17/064 , A61B17/2812 , A61B2017/00243 , A61B2017/00398 , A61B2017/00407 , A61B2017/00473 , A61B2017/00738 , A61B2017/00858 , A61B2017/0649 , A61B2090/061 , A61B2090/0801 , A61F2002/2484 , A61F2210/0033 , A61F2210/0076 , A61F2220/0016 , A61F2220/0025 , A61F2220/0033 , A61F2220/0083 , A61F2230/0013 , A61F2230/0023 , A61F2250/001 , A61F2250/0002 , A61F2250/0003 , A61F2250/0004 , A61F2250/006 , A61F2250/0007 , A61F2250/0029 , A61F2250/0036 , A61F2250/0064
摘要： A self-adjusting device configured to be placed in contact with tissue/organ and apply mechanical force to the tissue/organ to achieve an improvement of functioning of the tissue/organ. The self-adjusting capabilities can be carried out by three functional subsystems that can be packaged either in a single, integrated system or in separate modules. A sensing subsystem senses the tissue/organ and sends at least one type of sensing signal characteristic of functioning of the tissue/organ to a controlling subsystem. The controlling subsystem processes the signal with an algorithm to determine if a configuration of the device needs to be changed or a force applied to the tissue/organ needs to be changed. An actuating subsystem can be controlled by the controlling subsystem to affect the configuration/force change when needed. A feedback loop is provided to keep the controlling subsystem up to date as to the state of the actuating subsystem.

3. 发明授权

US09901478B2 Methods and apparatuses for the external distraction in the assistance of spinal deformities 有权
公开(公告)号：US09901478B2
公开(公告)日：2018-02-27
申请号：US14645218
申请日：2015-03-11
申请人： CHINE, LLC
发明人： John MacMahon , Edward Brian MacMahon , Tom Saul
IPC分类号： A61F5/00 , A61F5/042
CPC分类号： A61F5/042 , A61F2005/0155 , A61F2005/0188
摘要： Spinal distraction systems including methods of use.

4. 发明申请

US20220118275A1 Apparatus and Methods for Phototherapy 有权
公开(公告)号：US20220118275A1
公开(公告)日：2022-04-21
申请号：US17566892
申请日：2021-12-31
申请人： Chine, LLC
发明人： John MacMahon
IPC分类号： A61N5/06
摘要： Apparatus and methods of controlled therapeutic modulation of an immune response by an immune system of a patient. UV radiation is applied to the skin of a patient for a predetermined time period or dose. The application of UV radiation is repeated for the predetermined time or dose or for a modified predetermined time period or dose based on patient feedback after applying for the predetermined time period or dose, multiple times, wherein each repetition is performed after a predetermined rest period has passed. The patient is tested after at least one session of application of UV radiation and levels of one or more indicators read by the test are compared to levels that were established as baseline levels from a test taken before the initial application of UV radiation. The treatments are discontinued when a predetermined differential threshold between retesting levels and baseline levels in at least one indicator has been met, or for a predetermined number of times, whichever occurs first.

5. 发明授权

US11247067B2 Apparatus and methods for phototherapy 有权
公开(公告)号：US11247067B2
公开(公告)日：2022-02-15
申请号：US17199068
申请日：2021-03-11
申请人： Chine, LLC
发明人： John MacMahon
IPC分类号： A61N5/06
摘要： Apparatus and methods of controlled therapeutic modulation of an immune response by an immune system of a patient. UV radiation is applied to the skin of a patient for a predetermined time period or dose. The application of UV radiation is repeated for the predetermined time or dose or for a modified predetermined time period or dose based on patient feedback after applying for the predetermined time period or dose, multiple times, wherein each repetition is performed after a predetermined rest period has passed. The patient is tested after at least one session of application of UV radiation and levels of one or more indicators read by the test are compared to levels that were established as baseline levels from a test taken before the initial application of UV radiation. The treatments are discontinued when a predetermined differential threshold between retesting levels and baseline levels in at least one indicator has been met, or for a predetermined number of times, whichever occurs first.

6. 发明授权

US11565122B2 Apparatus and methods for phototherapy 有权
公开(公告)号：US11565122B2
公开(公告)日：2023-01-31
申请号：US17566892
申请日：2021-12-31
申请人： Chine, LLC
发明人： John MacMahon
IPC分类号： A61N5/00 , A61N5/06
摘要： Apparatus and methods of controlled therapeutic modulation of an immune response by an immune system of a patient. UV radiation is applied to the skin of a patient for a predetermined time period or dose. The application of UV radiation is repeated for the predetermined time or dose or for a modified predetermined time period or dose based on patient feedback after applying for the predetermined time period or dose, multiple times, wherein each repetition is performed after a predetermined rest period has passed. The patient is tested after at least one session of application of UV radiation and levels of one or more indicators read by the test are compared to levels that were established as baseline levels from a test taken before the initial application of UV radiation. The treatments are discontinued when a predetermined differential threshold between retesting levels and baseline levels in at least one indicator has been met, or for a predetermined number of times, whichever occurs first.

7. 发明申请

US20210283420A1 Apparatus and Methods for Phototherapy 有权
公开(公告)号：US20210283420A1
公开(公告)日：2021-09-16
申请号：US17199068
申请日：2021-03-11
申请人： Chine, LLC
发明人： John MacMahon
IPC分类号： A61N5/06
摘要： Apparatus and methods of controlled therapeutic modulation of an immune response by an immune system of a patient. UV radiation is applied to the skin of a patient for a predetermined time period or dose. The application of UV radiation is repeated for the predetermined time or dose or for a modified predetermined time period or dose based on patient feedback after applying for the predetermined time period or dose, multiple times, wherein each repetition is performed after a predetermined rest period has passed. The patient is tested after at least one session of application of UV radiation and levels of one or more indicators read by the test are compared to levels that were established as baseline levels from a test taken before the initial application of UV radiation. The treatments are discontinued when a predetermined differential threshold between retesting levels and baseline levels in at least one indicator has been met, or for a predetermined number of times, whichever occurs first.

8. 发明授权

US11957586B2 Epicardial valve repair system 有权
公开(公告)号：US11957586B2
公开(公告)日：2024-04-16
申请号：US16964975
申请日：2019-01-25
申请人： Evan Anderson , John MacMahon , Jeremy Boyette , Christopher Pell , Michael Stewart , Mark Juravic , Mitre Medical Corp.
发明人： Evan Anderson , John MacMahon , Jeremy Boyette , Christopher Pell , Michael Stewart , Mark Juravic
IPC分类号： A61F2/24 , A61B17/068 , A61B17/10 , A61B90/00 , A61B17/00 , A61B17/064 , A61B17/28
CPC分类号： A61F2/2481 , A61B17/068 , A61B17/10 , A61B90/06 , A61F2/2442 , A61F2/2451 , A61F2/246 , A61F2/2466 , A61F2/2478 , A61B2017/00243 , A61B2017/00398 , A61B2017/00407 , A61B2017/00473 , A61B2017/00738 , A61B2017/00858 , A61B17/064 , A61B2017/0649 , A61B17/2812 , A61B2090/061 , A61B2090/0801 , A61F2002/2484 , A61F2210/0033 , A61F2210/0076 , A61F2220/0016 , A61F2220/0025 , A61F2220/0033 , A61F2220/0083 , A61F2230/0013 , A61F2230/0023 , A61F2250/0002 , A61F2250/0003 , A61F2250/0004 , A61F2250/0007 , A61F2250/001 , A61F2250/0029 , A61F2250/0036 , A61F2250/006 , A61F2250/0064
摘要： Devices, systems and methods for altering functioning of a tissue/organ by application of force thereto. In one preferred embodiment, a device for reducing or preventing regurgitation of blood through a valve of a heart is provided. A device may include a main body having a segment adapted to apply force to a surface of tissue/organ and a member that applies counterforce to the force applied by the segment. Kits are provided in which devices having varying lengths and widths can be selected for the best fit for a particular location of treatment. A width sizing instrument may be provided. A length sizing instrument may be provided. A separate sleeve and/or pad may be provided which may be first anchored to the tissue/organ before fixing the device thereto.

9. 发明申请

US20210045878A1 Epicardial Valve Repair System 有权
公开(公告)号：US20210045878A1
公开(公告)日：2021-02-18
申请号：US16964975
申请日：2019-01-25
申请人： Evan Anderson , John MacMahon , Jeremy Boyette , Christopher Pell , Michael Stewart , Mark Juravic , Mitre Medical Corp.
发明人： Evan Anderson , John MacMahon , Jeremy Boyette , Christopher Pell , Michael Stewart , Mark Juravic
IPC分类号： A61F2/24
摘要： Devices, systems and methods for altering functioning of a tissue/organ by application of force thereto. In one preferred embodiment, a device for reducing or preventing regurgitation of blood through a valve of a heart is provided. A device may include a main body having a segment adapted to apply force to a surface of tissue/organ and a member that applies counterforce to the force applied by the segment. Kits are provided in which devices having varying lengths and widths can be selected for the best fit for a particular location of treatment. A width sizing instrument may be provided. A length sizing instrument may be provided. A separate sleeve and/or pad may be provided which may be first anchored to the tissue/organ before fixing the device thereto.

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