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1. 发明申请

US20050187276A1 Compounds, compositions and methods 失效
标题翻译：化合物，组合物和方法
公开(公告)号：US20050187276A1
公开(公告)日：2005-08-25
申请号：US10883482
申请日：2004-06-30
申请人： Jong-Wan Park , Yang-Sook Chun , Kenneth Bair , Ho Cho
发明人： Jong-Wan Park , Yang-Sook Chun , Kenneth Bair , Ho Cho
IPC分类号： A61K20060101 , A61K31/415 , A61K31/4172
CPC分类号： A61K31/416 , A61K31/4184 , C07D231/56 , C07D401/04 , C07D403/04 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/14 , C07D417/04 , C07D417/14
摘要： The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions.
摘要翻译：本发明提供了抑制HIF和HIF调节基因表达，抑制血管发生，诱导肿瘤细胞中的细胞周期停滞以及治疗细胞增殖性疾病或病症的方法和药物组合物。

2. 发明申请

US20050096370A1 Method for inhibiting tumor angiogenesis and tumor growth 审中-公开
标题翻译：抑制肿瘤血管生成和肿瘤生长的方法
公开(公告)号：US20050096370A1
公开(公告)日：2005-05-05
申请号：US10642363
申请日：2003-08-14
申请人： Jong-Wan Park , Yang-Sook Chun , Jinho Kim
发明人： Jong-Wan Park , Yang-Sook Chun , Jinho Kim
IPC分类号： A61K31/416
CPC分类号： A61K31/416
摘要： The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF-1 and HIF-1-regulated genes, angiogenesis, tumor growth, or tumor progression/metastasis comprising contacting the tumor cells or tissue with a composition comprising 3-(5′-hydroxymethyl-2′-furyl)-1-benzylindazole, or a novel derivative thereof.
摘要翻译：本发明提供了用于抑制HIF-1和HIF-1调节基因表达，血管发生，肿瘤生长或肿瘤进展/转移的方法和药物组合物，包括使肿瘤细胞或组织与包含3-（5'- 羟甲基-2'-呋喃基）-1-苯并吲唑或其新型衍生物。

3. 发明申请

US20050062973A1 Surface plasmon optic devices and radiating surface plasmon sources for photolithography 有权
标题翻译：表面等离子体光学器件和用于光刻的辐射表面等离子体源
公开(公告)号：US20050062973A1
公开(公告)日：2005-03-24
申请号：US10494814
申请日：2001-11-10
申请人： Dai-Sik Kim , Sung-Chul Hohng , Christoph Lienau , Victor Malyarchuck , Jong-Wan Park , Yeo-Chan Yoon , Han-Youl Ryu , Kyeong-Hwa Yoo
发明人： Dai-Sik Kim , Sung-Chul Hohng , Christoph Lienau , Victor Malyarchuck , Jong-Wan Park , Yeo-Chan Yoon , Han-Youl Ryu , Kyeong-Hwa Yoo
IPC分类号： G02B6/12 , G02B6/10 , G02F1/01 , G03F7/20 , G01N21/55
CPC分类号： G03F7/70375 , G02B6/10 , G02F1/01 , G02F2203/10
摘要： Disclosed is a surface plasmon optic device that has a periodic array of apertures in a dielectric substrate and a metal film formed on the dielectric substrate and emits light from metal-air interface. The surface plasmon optic device includes a surface plasmon generating apparatus, a surface plasmon detecting apparatus, a surface plasmon controlling apparatus, an etching apparatus, etc. if a metal diffraction grating is disposed on the metal film having a well-defined interface, propagation of the surface plasmon can be efficiently reflected, divided and controlled. Further, radiating surface plasmon having a half period of a lattice constant formed at air-metal (1, 0) can be preserved at a distance of at least a few micron.
摘要翻译：公开了一种表面等离子体激元光学器件，其在电介质基底中具有周期性的孔阵列，并且在电介质基底上形成金属膜，并从金属 - 空气界面发射光。如果将金属衍射光栅设置在具有界定界面的金属膜上，则表面等离子体激元装置包括表面等离子体激元产生装置，表面等离子体激元检测装置，表面等离子体激元控制装置，蚀刻装置等。可以有效地反射，分割和控制表面等离子体激元。此外，具有在空气 - 金属（1,0）处形成的晶格常数的半周期的辐射表面等离子体可以保持在至少几微米的距离处。

4. 发明授权

US07592239B2 Flexible single-crystal film and method of manufacturing the same 有权
标题翻译：柔性单晶膜及其制造方法
公开(公告)号：US07592239B2
公开(公告)日：2009-09-22
申请号：US10833050
申请日：2004-04-28
申请人： Jong-Wan Park , Jea-Gun Park
发明人： Jong-Wan Park , Jea-Gun Park
IPC分类号： H01L21/20
CPC分类号： H01L21/76254 , H01L27/1214 , H01L27/1266 , H01L29/78603 , H01L31/18
摘要： The present invention relates to a flexible single-crystal film and a method of manufacturing the same from a single-crystal wafer. That is, the present invention can manufacture a silicon-on-insulator (SOI) wafer comprising a base wafer, one or more buried insulator layers, and a single-crystal layer into a flexible single-crystal film with a desired thickness by employing various wafer thinning techniques. The method for manufacturing a flexible film comprises the steps of (i) providing a SOI wafer comprising a base wafer, one or more buried insulator layers on the base wafer, and a single-crystal layer on said one or more buried insulator layers, (ii) forming one or more protective insulator layers on said single-crystal layer, (iii) removing said base wafer, and (iv) removing one or more of the insulator layers.
摘要翻译：本发明涉及柔性单晶膜及其制造方法。也就是说，本发明可以通过采用各种各样的方式制造包括基底晶片，一个或多个掩埋绝缘体层和单晶层的具有期望厚度的柔性单晶膜的绝缘体上硅（SOI）晶片晶圆薄化技术。制造柔性膜的方法包括以下步骤：（i）提供包括基底晶片，基底晶片上的一个或多个掩埋绝缘体层和所述一个或多个掩埋绝缘体层上的单晶层的SOI晶片（ ii）在所述单晶层上形成一个或多个保护性绝缘体层，（iii）去除所述基底晶片，和（iv）去除一个或多个绝缘体层。

5. 发明授权

US07359598B2 Surface plasmon optic devices and radiating surface plasmon sources for photolithography 有权
标题翻译：表面等离子体光学器件和用于光刻的辐射表面等离子体源
公开(公告)号：US07359598B2
公开(公告)日：2008-04-15
申请号：US10494814
申请日：2001-11-10
申请人： Dai-Sik Kim , Sung-Chul Hohng , Christoph Lienau , Victor Malyarchuck , Jong-Wan Park , Yeo-Chan Yoon , Han-Youl Ryu , Kyeong-Hwa Yoo
发明人： Dai-Sik Kim , Sung-Chul Hohng , Christoph Lienau , Victor Malyarchuck , Jong-Wan Park , Yeo-Chan Yoon , Han-Youl Ryu , Kyeong-Hwa Yoo
IPC分类号： G02B6/26 , G02B6/42
CPC分类号： G03F7/70375 , G02B6/10 , G02F1/01 , G02F2203/10
摘要： Disclosed is a surface plasmon optic device that has a periodic array of apertures in a dielectric substrate and a metal film formed on the dielectric substrate and emits light from metal-air interface. The surface plasmon optic device includes a surface plasmon generating apparatus, a surface plasmon detecting apparatus, a surface plasmon controlling apparatus, an etching apparatus, etc. if a metal diffraction grating is disposed on the metal film having a well-defined interface, propagation of the surface plasmon can be efficiently reflected, divided and controlled. Further, radiating surface plasmon having a half period of a lattice constant formed at air-metal (1, 0) can be preserved at a distance of at least a few micron.
摘要翻译：公开了一种表面等离子体激元光学器件，其在电介质基底中具有周期性的孔阵列，并且在电介质基底上形成金属膜，并从金属 - 空气界面发射光。如果将金属衍射光栅设置在具有界定良好界面的金属膜上，则表面等离子体激元装置包括表面等离子体激元产生装置，表面等离子体激元检测装置，表面等离子体激元控制装置，蚀刻装置等。可以有效地反射，分割和控制表面等离子体激元。此外，具有在空气 - 金属（1,0）处形成的晶格常数的半周期的辐射表面等离子体可以保持在至少几微米的距离处。

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