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1. 发明申请

US20080082686A1 Internet provider subscriber communications system 有权
标题翻译：互联网提供商用户通信系统
公开(公告)号：US20080082686A1
公开(公告)日：2008-04-03
申请号：US11895623
申请日：2007-08-24
申请人： Jonathan Schmidt , Henry Donzis , Lewis Donzis , Rodney Erey , John Murphy
发明人： Jonathan Schmidt , Henry Donzis , Lewis Donzis , Rodney Erey , John Murphy
IPC分类号： G06F15/173
CPC分类号： H04L65/60 , H04L29/06 , H04L67/02 , H04L67/22 , H04L67/2814 , H04L67/2819 , H04L67/2871 , H04L69/329
摘要： A system, method, and computer readable medium for communicating at least one real-time specially-composed bulletin message to at least one subscriber of a provider of Internet services, comprising a first device, and a second device communicably coupled to the first device, wherein the first device: accesses only subscriber upstream traffic to a destination web site requested by the subscriber, wherein the first device inter-connects between the at least one subscriber and the destination web site, identifies the at least one subscriber's unique identification based on the accessed subscriber upstream traffic automatically provided by the subscriber, and provides the unique subscriber identification to the second device located at the provider of Internet services providing data services and management control to the first device, wherein the second device determines the subscriber associated with the unique subscriber identification, and if the specially-composed bulletin message for the subscriber is desired to be communicated: the second device sends policy information related to the data services and management control, to the first device, wherein the policy information includes an IP address of the subscriber's device, and at least one of: the specially-composed bulletin message, a modification of the message to be performed for the IP address, a reference to the message, and a redirection to the message, the first device examines the accessed upstream traffic to determine if it is possible to send a redirection, wherein the examining occurs without modifying the accessed upstream traffic, and the first device sends the redirection if it is possible to do so.
摘要翻译：一种系统，方法和计算机可读介质，用于将包括第一设备和可通信地耦合到第一设备的第二设备的因特网服务提供商的至少一个用户传送至少一个实时专用公告消息，其中所述第一设备：仅将订户上游流量访问到由所述订户请求的目的地网站，其中所述第一设备在所述至少一个用户与所述目的地网站之间进行互连，基于所述至少一个用户的唯一标识识别所述至少一个用户的唯一标识由用户自动提供的访问用户上行流量，并且向位于提供数据服务和管理控制的因特网服务提供商处的第二设备向第一设备提供唯一的用户标识，其中第二设备确定与唯一用户相关联的用户识别，如果是专门的公告信息希望通信用户：第二设备向第一设备发送与数据业务和管理控制有关的策略信息，其中策略信息包括用户设备的IP地址，以及以下至少一个：组合公告消息，要对IP地址执行的消息的修改，对消息的引用以及对消息的重定向，第一设备检查所访问的上行流量以确定是否可能发送重定向，其中在不修改所访问的上游流量的情况下进行检查，并且如果可以这样做，则第一设备发送重定向。

2. 发明授权

US5867660A Method and apparatus for communicating between a network workstation and an internet 失效
标题翻译：用于在网络工作站和互联网之间通信的方法和装置
公开(公告)号：US5867660A
公开(公告)日：1999-02-02
申请号：US439136
申请日：1995-05-11
申请人： Jonathan Schmidt , Lewis Donzis , Henry Donzis , John Murphy , Peter Baron
发明人： Jonathan Schmidt , Lewis Donzis , Henry Donzis , John Murphy , Peter Baron
IPC分类号： H04L29/06 , H04L29/08 , G06F13/00
CPC分类号： H04L29/06 , H04L69/161 , H04L69/162 , H04L67/42 , H04L69/16 , H04L69/32
摘要： An apparatus and method for connecting a plurality of LAN workstations to the internet via an on-line server/interface that does not require a PC operating system dedicated to the server. The server operates in TCP/IP protocol for communication over the Internet. Only a single connection to the Internet is required in order to permit the entire LAN to operate simultaneously on the Internet. Specifically, only a single phone line is required to simultaneously serve all LAN workstations. The system is equally well suited to connect via a telephone line connection to an Internet providers's slip or PPP or via an Ethernet connection to a router or direct connection by any available means. The system does not disturb the native LAN protocol, while communicating via the internet protocol such as, by way of example, TCP/IP. The LAN is provided with a complete internet protocol service, supporting functions not generally available in the dedicated stacks previously provided for individual PCs.
摘要翻译：一种用于通过不需要专用于服务器的PC操作系统的在线服务器/接口将多个LAN工作站连接到因特网的装置和方法。服务器以TCP / IP协议运行，用于通过Internet进行通信。为了允许整个局域网在互联网上同时运行，只需要连接到互联网的单一连接。具体来说，只需要一条电话线即可同时为所有LAN工作站提供服务。该系统同样适合通过电话线路连接到互联网供应商的单据或PPP，或通过以太网连接到路由器或通过任何可用的方式进行直接连接。当通过例如TCP / IP的网络协议进行通信时，该系统不会干扰本地LAN协议。 LAN提供完整的互联网协议服务，支持以前为个人PC提供的专用堆栈中通常不可用的功能。

3. 发明授权

US5991807A System for controlling users access to a distributive network in accordance with constraints present in common access distributive network interface separate from a server 失效
标题翻译：用于根据存在于与服务器分离的公共接入分配网络接口中的约束来控制用户对分布式网络的访问的系统
公开(公告)号：US5991807A
公开(公告)日：1999-11-23
申请号：US669053
申请日：1996-06-24
申请人： Jonathan Schmidt , Lewis Donzis , Henry Donzis , John Murphy , Peter Baron , Herb Savage
发明人： Jonathan Schmidt , Lewis Donzis , Henry Donzis , John Murphy , Peter Baron , Herb Savage
IPC分类号： G06F13/00
CPC分类号： H04L12/2876 , H04L12/2858
摘要： A method of managing access to a distributive network provides both time and site access restraints for users or groups of users on a LAN or WAN adapted for accessing the network through a common network access interface system. The method utilizes the LAN server to develop and monitor the constraints, minimizing the utilization of the access interface system. The management parameters for each group or individual having access to the distributive network via the LAN or WAN is entered into the interface box by the administrator as a compact reference, a series of pointers to the larger database of users and groups stored in the existing LAN server directory services. The existing database of users and groups and their relationships exist already in the LAN servers as a normal consequence of LAN operation and a simple, graphical user interface in the preferred embodiment of the invention permits familiar selection of objects of that database and assignment of access constraints.
摘要翻译：管理对分配网络的访问的方法为适于通过公共网络访问接口系统访问网络的LAN或WAN上的用户或用户组提供时间和站点访问限制。该方法利用LAN服务器开发和监控约束，最大限度地减少访问接口系统的利用率。经由LAN或WAN访问分布式网络的每个组或个人的管理参数由管理员作为紧凑参考输入到接口盒中，一系列指向存储在现有LAN中的用户和组的较大数据库的指针服务器目录服务。用户和组的现有数据库及其关系已经作为LAN操作的正常结果已经存在于LAN服务器中，并且在本发明的优选实施例中的简单的图形用户界面允许对该数据库的对象的熟悉选择和访问约束的分配。

4. 发明授权

US06425013B1 Apparartus for interconnecting local area network workstations to an internet via a single protocol stack system with segregated socket services 失效
标题翻译： Apparartus通过具有隔离套接字服务的单个协议栈系统将局域网工作站与Internet互连
公开(公告)号：US06425013B1
公开(公告)日：2002-07-23
申请号：US09227022
申请日：1999-01-07
申请人： Jonathan Schmidt , Lewis Donzis , Henry Donzis , John Murphy , Peter Baron
发明人： Jonathan Schmidt , Lewis Donzis , Henry Donzis , John Murphy , Peter Baron
IPC分类号： G06F1516
CPC分类号： H04L29/06 , H04L67/42 , H04L69/16 , H04L69/161 , H04L69/162 , H04L69/32
摘要： An apparatus and method for connecting a plurality of LAN workstations to the internet via an on-line server/interface that does not require a PC operating system dedicated to the server. The server operates in TCP/IP protocol for communication over the Internet. Only a single connection to the Internet is required in order to permit the entire LAN to operate simultaneously on the Internet. Specifically, only a single phone line is required to simultaneously serve all LAN workstations. The system is equally well suited to connect via a telephone line connection to an Internet providers's slip or PPP or via an Ethernet connection to a router or direct connection by any available means. The system does not disturb the native LAN protocol, while communicating via the internet protocol such as, by way of example, TCP/IP. The LAN is provided with a complete internet protocol service, supporting functions not generally available in the dedicated stacks previously provided for individual PCs.
摘要翻译：一种用于通过不需要专用于服务器的PC操作系统的在线服务器/接口将多个LAN工作站连接到因特网的装置和方法。服务器以TCP / IP协议运行，用于通过Internet进行通信。为了允许整个局域网在互联网上同时运行，只需要连接到互联网的单一连接。具体来说，只需要一条电话线即可同时为所有LAN工作站提供服务。该系统同样适合通过电话线路连接到互联网供应商的单据或PPP，或通过以太网连接到路由器或通过任何可用的方式进行直接连接。当通过例如TCP / IP的网络协议进行通信时，该系统不会干扰本地LAN协议。 LAN提供完整的互联网协议服务，支持以前为个人PC提供的专用堆栈中通常不可用的功能。

5. 发明授权

US09095681B2 Catheter system 有权
标题翻译：导管系统
公开(公告)号：US09095681B2
公开(公告)日：2015-08-04
申请号：US12626531
申请日：2009-11-25
申请人： Tal Wenderow , Thomas Bromander , James J. Kennedy, III , Stanley O. Thompson , Jon B. Taylor , Jeffrey Lightcap , John Murphy , Graham Eacock
发明人： Tal Wenderow , Thomas Bromander , James J. Kennedy, III , Stanley O. Thompson , Jon B. Taylor , Jeffrey Lightcap , John Murphy , Graham Eacock
IPC分类号： A61M25/00 , A61B19/00 , A61M25/01 , A61M25/09 , A61B17/00
CPC分类号： A61M25/0147 , A61B17/00234 , A61B34/30 , A61B90/98 , A61B2017/00323 , A61B2017/00477 , A61B2034/301 , A61M25/0113 , A61M25/09041
摘要： A catheter system including a housing and a first drive mechanism supported by the housing configured to impart movement to a first catheter device is provided. The first drive mechanism is moveable between an engaged position in which the first drive mechanism engages the first catheter device and a disengaged position in which the first drive mechanism does not engage the first catheter device. The catheter system includes a second drive mechanism supported by the housing configured to impart movement to a second catheter device. The second drive mechanism is moveable between an engaged position in which the second drive mechanism engages the second catheter device and a disengaged position in which the second drive mechanism does not engage the second catheter device. The catheter system includes a manual control configured to allow a user to manually move the first drive mechanism and the second drive mechanism between the engaged and disengaged positions. The first drive mechanism and the second drive mechanism are also configured to be moved between the engaged and disengaged positions by an electronic actuator responsive to a user's activation of a control. The first drive mechanism and the second drive mechanism are configured to be moved between the respective engaged and disengaged positions synchronized with each other.
摘要翻译：提供了一种导管系统，其包括壳体和由所述壳体支撑的第一驱动机构，所述第一驱动机构构造成将移动传递给第一导管装置。第一驱动机构可在其中第一驱动机构接合第一导管装置的接合位置与第一驱动机构不接合第一导管装置的分离位置之间移动。导管系统包括由壳体支撑的第二驱动机构，该第二驱动机构构造成将运动传递给第二导管装置。第二驱动机构可在其中第二驱动机构接合第二导管装置的接合位置与第二驱动机构不接合第二导管装置的分离位置之间移动。导管系统包括手动控制器，其被配置为允许使用者在接合位置和脱离位置之间手动地移动第一驱动机构和第二驱动机构。第一驱动机构和第二驱动机构还构造成通过响应于用户对控制的激活的电子执行器在接合位置和脱离位置之间移动。第一驱动机构和第二驱动机构构造成在彼此同步的相应的接合位置和脱离位置之间移动。

6. 发明申请

US20130231631A1 ROBOTIC CATHETER SYSTEM WITH VARIABLE SPEED CONTROL 有权
标题翻译：具有可变速度控制的机器人导管系统
公开(公告)号：US20130231631A1
公开(公告)日：2013-09-05
申请号：US13600824
申请日：2012-08-31
申请人： John Murphy , Tal Wenderow , David Handler
发明人： John Murphy , Tal Wenderow , David Handler
IPC分类号： A61M25/01
CPC分类号： A61M25/0105 , A61B34/30 , A61B2017/00243 , A61B2034/301 , A61B2090/376 , A61M25/0113
摘要： A robotic catheter procedure system for performing a procedure on a patient is provided. The robotic catheter procedure system includes a bedside system and a remote workstation. The bedside system includes a percutaneous device and an actuating mechanism configured to engage and to impart movement to the percutaneous device. The remote workstation includes a user interface configured to receive a user input and a display device configured to display an image of a portion of the patient. The image includes a magnification level. The workstation also includes a control system operatively coupled to the user interface. The control system is configured to generate a control signal. The actuating mechanism causes movement of the percutaneous device in response to the control signal, and the control signal is based upon the user input and the magnification level.
摘要翻译：提供了一种用于对患者进行手术的机器人导管程序系统。机器人导管程序系统包括床边系统和远程工作站。床边系统包括经皮装置和致动机构，其构造成接合和赋予经皮装置的运动。远程工作站包括被配置为接收用户输入的用户界面和被配置为显示患者的一部分的图像的显示设备。图像包括放大级别。工作站还包括可操作地耦合到用户界面的控制系统。控制系统被配置为产生控制信号。致动机构响应于控制信号引起经皮装置的移动，并且控制信号基于用户输入和放大级别。

7. 外观设计

USD685468S1 Catheter system cassette 有权
标题翻译：导管系统盒
公开(公告)号：USD685468S1
公开(公告)日：2013-07-02
申请号：US29427515
申请日：2012-07-19
申请人： John Murphy , Stephen Guerrera , Tal Wenderow
设计人： John Murphy , Stephen Guerrera , Tal Wenderow
CPC分类号： A61M25/0147 , A61B17/00234 , A61B34/30 , A61B90/98 , A61B2017/00323 , A61B2017/00477 , A61B2034/301 , A61M25/0113 , A61M25/09041
摘要： A catheter drive cassette configured to be removably coupled to a motor drive base, comprising a first axial drive mechanism configured to drive a guide wire along its longitudinal axis; a second axial drive mechanism configured to drive a working catheter along its longitudinal axis; and a first rotational drive mechanism configured to rotate the guide wire about its longitudinal axis.

8. 发明申请

US20080097408A1 Pullback Carriage Interlock System and Method for Catheter System 审中-公开
标题翻译：牵引车联锁系统和导管系统的方法
公开(公告)号：US20080097408A1
公开(公告)日：2008-04-24
申请号：US11875615
申请日：2007-10-19
申请人： John Murphy , Peter Strickler
发明人： John Murphy , Peter Strickler
IPC分类号： A61M25/16
CPC分类号： A61B5/6852 , A61B5/0066 , A61B8/12 , A61B8/4461
摘要： An optical catheter system comprising an intraluminal catheter that provides optical signals to a patient and carries optical signals from the patient, an outer housing, and an inner carriage that moves longitudinally relative to the outer housing and rotates relative to the outer housing during operation when the catheter system is being driven by a pullback and rotation system. The optical catheter system has an interlock system that prevents rotation and longitudinal movement of the inner carriage in the outer housing until attached to the pullback and rotation system. The pullback and rotation system comprises a frame and a catheter system interface, attached to the frame, to which the catheter system is coupled. A carriage drive system is further provided that moves longitudinally and rotates relative to the frame to provide rotation and longitudinal drive to the catheter system. A longitudinal drive system has a drive motor for advancing and/or withdrawing the carriage drive system and a manual drive input enabling a user to manually advance or withdrawal the carriage drive system. A latching system holds the carriage drive system when the catheter system is being attached to the pullback system.
摘要翻译：一种光学导管系统，其包括管腔内导管，其向患者提供光信号并且携带来自患者的光信号，外壳和内托架，所述光信号在操作期间相对于所述外壳在纵向相对运动时相对于所述外壳旋转，导管系统由拉回和旋转系统驱动。光学导管系统具有互锁系统，其防止内部托架在外部壳体中的旋转和纵向运动，直到附接到回拉和旋转系统。回拉和旋转系统包括附接到框架的框架和导管系统接口，导管系统连接到框架和导管系统接口。还提供了一种托架驱动系统，该托架驱动系统纵向移动并相对于框架旋转以向导管系统提供旋转和纵向驱动。纵向驱动系统具有用于前进和/或退出托架驱动系统的驱动马达和使用户能够手动前进或退出托架驱动系统的手动驱动输入。当导管系统连接到回拉系统时，闩锁系统保持托架驱动系统。

9. 发明申请

US20070238670A1 Novel compositions and methods for promoting, inhibiting and detecting protein entry into cells 失效
标题翻译：用于促进，抑制和检测蛋白质进入细胞的新型组合物和方法
公开(公告)号：US20070238670A1
公开(公告)日：2007-10-11
申请号：US11214997
申请日：2005-08-30
申请人： John Murphy , Ryan Ratts
发明人： John Murphy , Ryan Ratts
IPC分类号： A61K38/08 , C07K7/06
CPC分类号： G01N33/5076 , A61K38/08 , C07K14/34 , C07K14/55 , C07K2319/55 , G01N33/5011 , G01N33/5035 , G01N2510/00
摘要： In vitro delivery of the diphtheria toxin (DT) catalytic (C) domain from the lumen of purified early endosomes to the external milieu requires the addition of both ATP and a cytosolic translocation factor (CTF) complex. The results presented here demonstrate that β-COP plays an essential role in the cytosolic release of the C-domain and is mediated by a consensus peptide sequence found on several bacterial toxins and in HIV-1 reverse transcriptase. The invention features methods for inhibiting cell death that include the administration of compounds based on this consensus sequence that inhibit the translocation of the catalytic domain of toxins or transcription factors. Also featured are methods for identifying compounds that inhibit cell death, and methods for identifying compounds that promote cell death by blocking or accelerating, respectively, the rate of toxin/factor endosomal translocation.
摘要翻译：将白喉毒素（DT）催化（C）结构域从纯化的早期内体的内部体外递送到外部环境需要添加ATP和胞质易位因子（CTF）复合物。这里提出的结果表明β-COP在C-结构域的胞质释放中起重要作用，并且由在几种细菌毒素和HIV-1逆转录酶中发现的共有肽序列介导。本发明的特征在于抑制细胞死亡的方法，包括基于抑制毒素或转录因子的催化结构域易位的共有序列的化合物的施用。还特征在于鉴定抑制细胞死亡的化合物的方法，以及通过阻断或加速毒素/因子内体易位的速率来鉴定促进细胞死亡的化合物的方法。

10. 发明申请

US20070110567A1 Axial and circumferential seal for stacked rotor and/or stator assembly 失效
标题翻译：用于堆叠转子和/或定子组件的轴向和周向密封
公开(公告)号：US20070110567A1
公开(公告)日：2007-05-17
申请号：US11270925
申请日：2005-11-11
申请人： Robert Bracken , John Murphy , Stephen Swan , Jeffrey Simkins , Clement Gazzillo
发明人： Robert Bracken , John Murphy , Stephen Swan , Jeffrey Simkins , Clement Gazzillo
IPC分类号： F04D29/08
CPC分类号： F01D5/026 , F01D5/06 , F01D5/34 , F01D11/00 , F01D11/003 , F01D11/005 , F02C7/28
摘要： Disclosed herein is a rotor assembly for a steam turbine including a stacked rotor section having rotor plates. The rotor plates include a main body portion having a plate shape and a first axial face and a second axial face opposite to the first axial face. The rotor plates also include an airfoil base surface at an outer radial edge of the main body portion. The rotor plates further include buckets which extend radially outward from the airfoil base surface. And the rotor plates yet further include a seal disposed to prevent steam exposure to the first and second axial faces.
摘要翻译：本文公开了一种用于蒸汽轮机的转子组件，其包括具有转子板的堆叠转子部分。转子板包括具有板形状的主体部分和与第一轴向面相对的第一轴向面和第二轴向面。转子板还包括在主体部分的外径向边缘处的翼型件基面。转子板还包括从翼型件基部表面径向向外延伸的铲斗。并且转子板还包括设置成防止蒸汽暴露于第一和第二轴向面的密封件。

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