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1. 发明授权

US08301264B2 Thermal therapy temperature sensor calibration method 有权
标题翻译：热疗温度传感器校准方法
公开(公告)号：US08301264B2
公开(公告)日：2012-10-30
申请号：US12387045
申请日：2009-04-27
申请人： Jonathan Achenbach , James E. Burgett , Claude Tihon , Allen Putnam
发明人： Jonathan Achenbach , James E. Burgett , Claude Tihon , Allen Putnam
IPC分类号： A61F2/00
CPC分类号： A61B18/04 , A61B2017/00084 , A61B2017/00725
摘要： A thermal therapy of body tissue with electromagnetic energy is controlled by feedback from one or more temperature sensors placed in the vicinity of the tissue to be treated. The temperature sensors are calibrated by comparing stabilized temperature values of the one or more temperature sensors against a normal range of body temperature and adjusting sensed temperature to a value within a normal body temperature range if the actual temperature value of a stabilized temperature sensor is less than the normal body temperature range. The temperature adjustment to the temperature sensor is maintained throughout the thermal therapy which reduces the risk of thermal damage to healthy tissue located near the tissue to be treated.
摘要翻译：具有电磁能的身体组织的热治疗通过放置在待治疗组织附近的一个或多个温度传感器的反馈来控制。通过将一个或多个温度传感器的稳定温度值与体温的正常范围进行比较，并将感测温度调整到正常体温范围内的值来校准温度传感器，如果稳定温度传感器的实际温度值小于正常体温范围。温度传感器的温度调节在整个热治疗过程中得到保持，从而降低了待处理组织附近的健康组织的热损伤风险。

2. 发明申请

US20090276017A1 Thermal therapy temperature sensor calibration method 有权
标题翻译：热疗温度传感器校准方法
公开(公告)号：US20090276017A1
公开(公告)日：2009-11-05
申请号：US12387045
申请日：2009-04-27
申请人： Jonathan Achenbach , James E. Burgett , Claude Tihon , Allen Putnam
发明人： Jonathan Achenbach , James E. Burgett , Claude Tihon , Allen Putnam
IPC分类号： A61F7/00
CPC分类号： A61B18/04 , A61B2017/00084 , A61B2017/00725
摘要： A thermal therapy of body tissue with electromagnetic energy is controlled by feedback from one or more temperature sensors placed in the vicinity of the tissue to be treated. The temperature sensors are calibrated by comparing stabilized temperature values of the one or more temperature sensors against a normal range of body temperature and adjusting sensed temperature to a value within a normal body temperature range if the actual temperature value of a stabilized temperature sensor is less than the normal body temperature range. The temperature adjustment to the temperature sensor is maintained throughout the thermal therapy which reduces the risk of thermal damage to healthy tissue located near the tissue to be treated.
摘要翻译：具有电磁能的身体组织的热治疗通过放置在待治疗组织附近的一个或多个温度传感器的反馈来控制。通过将一个或多个温度传感器的稳定温度值与体温的正常范围进行比较，并将感测温度调整到正常体温范围内的值来校准温度传感器，如果稳定温度传感器的实际温度值小于正常体温范围。温度传感器的温度调节在整个热治疗过程中得到保持，从而降低了待处理组织附近的健康组织的热损伤风险。

3. 发明授权

US06490488B1 Method of controlling thermal therapy 有权
标题翻译：控制热疗的方法
公开(公告)号：US06490488B1
公开(公告)日：2002-12-03
申请号：US09552905
申请日：2000-04-20
申请人： Eric N. Rudie , Jonathan L. Flachman , James E. Burgett , Thayne R. Larson
发明人： Eric N. Rudie , Jonathan L. Flachman , James E. Burgett , Thayne R. Larson
IPC分类号： B61N502
CPC分类号： A61B18/1815 , A61B2017/00084 , A61B2017/00274 , A61B2018/00023 , A61B2018/00547
摘要： A thermal therapy method includes inserting an applicator including an energy-emitting device into a body cavity such as a urethra adjacent a targeted tissue region such as a prostate, energizing the energy-emitting device, and circulating coolant between the energy-emitting device and a wall of the body cavity. The therapy is controlled by decreasing a temperature of the coolant and continually adjusting coolant temperature based on therapy parameters. The applicator, or selected tissue at a predetermined depth from the wall of the body cavity, is maintained at a temperature corresponding to a predetermined applicator temperature profile by adjusting a power level provided to the energy-emitting device. In one embodiment involving treatment of the prostate, rectal temperature is monitored and, upon sensing a rectal temperature that exceeds a predetermined threshold, the temperature of the coolant is increased to force a reduction in power provided to the energy-emitting device to maintain the applicator at the temperature corresponding to the predetermined applicator temperature profile.
摘要翻译：一种热疗法包括将包括能量发射装置的施放器插入诸如前列腺等目标组织区域的体腔内的尿道内，激发能量发射装置，以及将能量发射装置和体腔壁。该治疗通过降低冷却剂的温度并基于治疗参数连续地调节冷却剂温度来控制。通过调节提供给能量发射装置的功率水平，将施加器或在体腔壁的预定深度处的选定组织保持在与预定的施用器温度分布相对应的温度。在涉及治疗前列腺的一个实施方案中，监测直肠温度，并且在检测到超过预定阈值的直肠温度时，增加冷却剂的温度以迫使提供给能量发射装置的功率降低以维持施用器在对应于预定施加器温度曲线的温度下。

4. 发明授权

US6122551A Method of controlling thermal therapy 有权
标题翻译：控制热疗的方法
公开(公告)号：US6122551A
公开(公告)日：2000-09-19
申请号：US210033
申请日：1998-12-11
申请人： Eric N. Rudie , Jonathan L. Flachman , James E. Burgett , Thayne R. Larson
发明人： Eric N. Rudie , Jonathan L. Flachman , James E. Burgett , Thayne R. Larson
IPC分类号： A61N5/04 , A61B17/00 , A61B18/18 , A61F7/08 , A61F7/12 , A61F2/00 , A61F7/00
CPC分类号： A61B18/1815 , A61B2017/00084 , A61B2017/00274 , A61B2018/00023 , A61B2018/00547
摘要： A thermal therapy method includes inserting a microwave antenna-containing applicator into a body cavity such as a urethra adjacent a targeted tissue region such as a prostate, energizing the microwave antenna, and circulating coolant between the microwave antenna and a wall of the body cavity. The therapy is controlled by decreasing a temperature of the coolant and continually adjusting coolant temperature based on other parameters. The applicator is maintained at a predetermined temperature set point by adjusting a power level provided to the microwave antenna. In one embodiment involving treatment of the prostate, rectal temperature is monitored and, upon sensing a rectal temperature that exceeds a predetermined threshold, the temperature of the coolant is increased to force a reduction in power provided to the microwave antenna to maintain the applicator at the predetermined temperature set point.
摘要翻译：一种热治疗方法包括将微波天线的施用器插入到邻近诸如前列腺的目标组织区域的体腔（例如尿道）中，激励微波天线，以及在微波天线和体腔的壁之间循环冷却剂。通过降低冷却剂的温度并根据其他参数连续调节冷却剂温度来控制治疗。通过调节提供给微波天线的功率电平，将施加器维持在预定的温度设定点。在涉及治疗前列腺的一个实施方案中，监测直肠温度，并且在感测到超过预定阈值的直肠温度时，增加冷却剂的温度以强制提供给微波天线的功率降低以将施用器维持在预定温度设定点。

5. 发明授权

US5843144A Method for treating benign prostatic hyperplasia with thermal therapy 失效
标题翻译：用热疗治疗良性前列腺增生的方法
公开(公告)号：US5843144A
公开(公告)日：1998-12-01
申请号：US494320
申请日：1995-06-26
申请人： Eric N. Rudie , Mitchell Dann , John M. Reid , Bruce H. Neilson , James V. Kauphusman , James E. Burgett , Stanley E. Kluge , Steven W. Norsted
发明人： Eric N. Rudie , Mitchell Dann , John M. Reid , Bruce H. Neilson , James V. Kauphusman , James E. Burgett , Stanley E. Kluge , Steven W. Norsted
IPC分类号： A61N5/02 , A61B18/18
CPC分类号： A61B18/1815 , A61B18/18
摘要： A method for treating an individual with diseased prostatic tissue, such as benign prostatic hyperplasia, includes inserting a catheter into a urethra to position a microwave antenna located within the catheter adjacent a prostatic region of the urethra. A microwave antenna is then driven within a power range for applying microwave energy substantially continuously to prostatic tissue to heat the prostatic tissue surrounding the microwave antenna at a temperature and for a time period sufficient to cause necrosis of the prostatic tissue.
摘要翻译：用于治疗具有患病前列腺组织（例如良性前列腺增生）的个体的方法包括将导管插入尿道以将位于尿道前列腺区域附近的微波天线定位。然后在功率范围内驱动微波天线，以将微波能量基本连续地施加到前列腺组织，以在足以引起前列腺组织坏死的温度和时间段加热微波天线周围的前列腺组织。

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