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1. 发明授权

US5843144A Method for treating benign prostatic hyperplasia with thermal therapy 失效
标题翻译：用热疗治疗良性前列腺增生的方法
公开(公告)号：US5843144A
公开(公告)日：1998-12-01
申请号：US494320
申请日：1995-06-26
申请人： Eric N. Rudie , Mitchell Dann , John M. Reid , Bruce H. Neilson , James V. Kauphusman , James E. Burgett , Stanley E. Kluge , Steven W. Norsted
发明人： Eric N. Rudie , Mitchell Dann , John M. Reid , Bruce H. Neilson , James V. Kauphusman , James E. Burgett , Stanley E. Kluge , Steven W. Norsted
IPC分类号： A61N5/02 , A61B18/18
CPC分类号： A61B18/1815 , A61B18/18
摘要： A method for treating an individual with diseased prostatic tissue, such as benign prostatic hyperplasia, includes inserting a catheter into a urethra to position a microwave antenna located within the catheter adjacent a prostatic region of the urethra. A microwave antenna is then driven within a power range for applying microwave energy substantially continuously to prostatic tissue to heat the prostatic tissue surrounding the microwave antenna at a temperature and for a time period sufficient to cause necrosis of the prostatic tissue.
摘要翻译：用于治疗具有患病前列腺组织（例如良性前列腺增生）的个体的方法包括将导管插入尿道以将位于尿道前列腺区域附近的微波天线定位。然后在功率范围内驱动微波天线，以将微波能量基本连续地施加到前列腺组织，以在足以引起前列腺组织坏死的温度和时间段加热微波天线周围的前列腺组织。

2. 发明授权

US5643335A Benign prostatic hyperplasia treatment catheter with urethral cooling 失效
标题翻译：良性前列腺增生治疗导尿管与尿道冷却
公开(公告)号：US5643335A
公开(公告)日：1997-07-01
申请号：US643081
申请日：1996-05-02
申请人： John M. Reid , James V. Kauphusman , Christopher H. Porter , Bruce H. Neilson
发明人： John M. Reid , James V. Kauphusman , Christopher H. Porter , Bruce H. Neilson
IPC分类号： A61B18/18 , A61N5/02
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02
摘要： A system for treatment of benign prostatic hyperplasia within intraprostatic tissue surrounding a urethra is disclosed. The system includes an intraurethral catheter having an intraurethral catheter shaft. An antenna is located within the catheter shaft for delivering heat to the intraprostatic tissue surrounding the urethra. Coolant fluid is circulated through a chamber located between the catheter shaft and the urethral wall.
摘要翻译：公开了一种用于治疗尿道周围的静脉前组织内的良性前列腺增生的系统。该系统包括具有尿道内导管轴的尿道内导管。天线位于导管轴内，用于将热量传递到尿道周围的静脉内组织。冷却剂流体通过位于导管轴和尿道壁之间的腔室循环。

3. 发明授权

US5931860A Benign prostatic hyperplasia treatment catheter with urethral cooling 失效
公开(公告)号：US5931860A
公开(公告)日：1999-08-03
申请号：US880664
申请日：1997-06-23
申请人： John M. Reid , James V. Kauphusman , Christopher H. Porter , Bruce H. Neilson
发明人： John M. Reid , James V. Kauphusman , Christopher H. Porter , Bruce H. Neilson
IPC分类号： A61B18/18 , A61N5/02
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02
摘要： A system for treatment of benign prostatic hyperplasia within intraprostatic tissue surrounding a urethra is disclosed. The system includes an intraurethral catheter having an intraurethral catheter shaft. An antenna is located within the catheter shaft for delivering heat to the intraprostatic tissue surrounding the urethra. Coolant fluid is circulated through a chamber located between the catheter shaft and the urethral wall.

4. 发明授权

US5464437A Benign prostatic hyperplasia treatment catheter with urethral cooling 失效
标题翻译：良性前列腺增生治疗导尿管与尿道冷却
公开(公告)号：US5464437A
公开(公告)日：1995-11-07
申请号：US88901
申请日：1993-07-08
申请人： John M. Reid , James V. Kauphusman , Christopher H. Porter , Bruce H. Neilson
发明人： John M. Reid , James V. Kauphusman , Christopher H. Porter , Bruce H. Neilson
IPC分类号： A61B18/18 , A61N5/02
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02
摘要： A system for treatment of benign prostatic hyperplasia within intraprostatic tissue surrounding a urethra is disclosed. The system includes an intraurethral catheter having an intraurethral catheter shaft. An antenna is located within the catheter shaft for delivering heat to the intraprostatic tissue surrounding the urethra. Coolant fluid is circulated through a chamber located between the catheter shaft and the urethral wall.
摘要翻译：公开了一种用于治疗尿道周围的静脉前组织内的良性前列腺增生的系统。该系统包括具有尿道内导管轴的尿道内导管。天线位于导管轴内，用于将热量传递到尿道周围的静脉内组织。冷却剂流体通过位于导管轴和尿道壁之间的腔室循环。

5. 发明授权

US5575811A Benign prostatic hyperplasia treatment catheter with urethral cooling 失效
公开(公告)号：US5575811A
公开(公告)日：1996-11-19
申请号：US447374
申请日：1995-05-23
申请人： John M. Reid , James V. Kauphusman , Christopher H. Porter , Bruce H. Neilson
发明人： John M. Reid , James V. Kauphusman , Christopher H. Porter , Bruce H. Neilson
IPC分类号： A61B18/18 , A61N5/02
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02
摘要： A system for treatment of benign prostatic hyperplasia within intraprostatic tissue surrounding a urethra is disclosed. The system includes an intraurethral catheter having an intraurethral catheter shaft. An antenna is located within the catheter shaft for delivering heat to the intraprostatic tissue surrounding the urethra. Coolant fluid is circulated through a chamber located between the catheter shaft and the urethral wall.

6. 发明授权

US4109642A Apparatus for ultrasonic arteriography 失效
标题翻译：超声动脉造影仪
公开(公告)号：US4109642A
公开(公告)日：1978-08-29
申请号：US454423
申请日：1974-03-25
申请人： John M. Reid , Merrill P. Spencer
发明人： John M. Reid , Merrill P. Spencer
IPC分类号： A61B8/06 , G01F1/66 , G01S15/50 , G01S15/89 , A61B10/00
CPC分类号： A61B8/4218 , A61B8/06 , G01F1/66 , G01S15/50 , G01S15/8979 , G01S15/8993 , G01N2291/02836
摘要： Continuous wave ultrasonic sound waves from a transmitter and receiver are highly focused to a width of approximately 1 millimeter or less and are transmitted and received through intersecting paths within the tissue of a patient. A doppler flow detector produces an image of the moving blood within the vessel. The transmitter and receiver are systematically scanned over the subject and the detected images are converted into visually intelligible pictures.An improved circuit for more clearly defining the flow picture of the moving blood particles utilizes a conventional directional doppler circuit plus a multiplier-differentiator-low pass filter circuit to automatically eliminate venous flow signals. A grey scale oscilloscope provides brightness intensity on the visual picture proportional to the velocity and direction of the blood flow for detecting stenosis in the vessel.A recording technique is disclosed for detecting atherosclerotic thickening of the artery wall.A multiple beam scanner is disclosed which requires movement only in the longitudinal direction of the vessel.
摘要翻译：来自发射器和接收器的连续波超声波被高度聚焦到大约1毫米或更小的宽度，并且通过患者组织内的相交路径被传送和接收。多普勒流量检测器产生血管内移动血液的图像。发射机和接收机被系统地扫描主体，并将检测到的图像转换成视觉上可理解的图像。

7. 发明授权

US07758542B2 Endourethral device and method 有权
标题翻译：尿道装置及方法
公开(公告)号：US07758542B2
公开(公告)日：2010-07-20
申请号：US11604959
申请日：2006-11-28
申请人： Mark J. Whalen , Lloyd K. Willard , John M. Reid
发明人： Mark J. Whalen , Lloyd K. Willard , John M. Reid
IPC分类号： A61M31/00
CPC分类号： A61M25/0017 , A61F2/0027 , A61M25/04 , A61M25/1011 , A61M2210/1089
摘要： Several embodiments of an endourethral prosthesis, assembly, and attendant methods are provided for patients presenting with lower urinary tract symptoms (LUTS) or urinary retention. The endourethral prosthesis includes a reversibly expandable element disposed circumferentially about, and longitudinally along a tubular member adapted to receive urine. The tubular member is positionable within a lower urinary tract such that the reversibly expandable element operatively engages a structure of the lower urinary tract so as to prevent migration of the prosthesis so positioned. The reversibly expandible element is in non-reversible fluid communication with the tubular element for selective expansion thereof, the reversibly expandible element is further operatively engagable so as to discharge fluid non-reversibly received from the tubular member exterior to same.
摘要翻译：为具有较低尿路症状（LUTS）或尿潴留的患者提供内尿道假体，组装和伴随方法的若干实施例。内尿道假体包括可逆地扩张的元件，其沿着适于接收尿液的管状构件周向地纵向设置。管状构件可定位在下尿路内，使得可逆扩张的元件可操作地接合下尿道的结构，以便防止如此定位的假体的移动。可逆膨胀元件与管状元件不可逆地流体连通，用于其选择性膨胀，可逆膨胀元件进一步可操作地接合，从而将外部不可逆地从管状构件接收的流体排出到外部。

8. 发明授权

US4575799A Ultrasonic living body tissue characterization system 失效
标题翻译：超声波生物体组织表征系统
公开(公告)号：US4575799A
公开(公告)日：1986-03-11
申请号：US477935
申请日：1983-03-23
申请人： Hirohide Miwa , John M. Reid
发明人： Hirohide Miwa , John M. Reid
IPC分类号： A61B8/00 , G01N29/00 , G01S7/52 , G01S15/89 , G01N29/04 , A61B10/00
CPC分类号： G01S15/8954 , G01S7/52025 , G01S7/52036
摘要： A method for ultrasonic living body tissue characterization using a transducer and processor. The method includes the steps of transmitting an ultrasonic pulse into the tissue and receiving a reflected pulse, calculating the normalized power frequency spectrum of the reflected pulse, determining the frequency at which the maximum value for the power spectrum occurs, determining the high and low half power frequencies, calculating the upper and lower frequency ratios of the maximum value frequency and the half power frequencies, and determining the power exponent of the frequency of the reflection coefficient. The frequency exponent of the reflection coefficient is used to calculate the attenuation slope of the ultrasonic wave. The attenuation slope or the reflection power exponent is used to generate a tomographic image of the living tissue characteristics for visual non-invasive tissue diagnosis. The attenuation slope and/or the reflection power exponent tomographic image or the others can be combined with a reflection intensity tomographic image or the others to produce other diagnostic images.
摘要翻译：一种使用换能器和处理器进行超声波生物体组织表征的方法。该方法包括以下步骤：将超声波脉冲发送到组织并接收反射脉冲，计算反射脉冲的归一化功率频谱，确定发生功率谱的最大值的频率，确定高低半功率频率，计算最大值频率和半功率频率的上，下频率比，并确定反射系数频率的幂指数。反射系数的频率指数用于计算超声波的衰减斜率。衰减斜率或反射功率指数用于产生用于视觉非侵入性组织诊断的活组织特征的断层图像。衰减斜率和/或反射功率指数断层图像等可以与反射强度断层图像等组合，以产生其他诊断图像。

9. 发明授权

US07141038B2 Endourethral device and method 有权
标题翻译：尿道装置及方法
公开(公告)号：US07141038B2
公开(公告)日：2006-11-28
申请号：US10343894
申请日：2001-08-07
申请人： Mark J. Whalen , Lloyd K. Wihlard , John M. Reid
发明人： Mark J. Whalen , Lloyd K. Wihlard , John M. Reid
IPC分类号： A61M29/00 , A61M31/00
CPC分类号： A61M25/0017 , A61F2/0027 , A61M25/04 , A61M25/1011 , A61M2210/1089
摘要： Several embodiments of an endourethral prosthesis, assembly, and attendant methods are provided for patients presenting with lower urinary tract symptoms (LUTS) or urinary retention. The endourethral prosthesis includes a reversibly expandable element disposed circumferentially about, and longitudinally along a tubular member adapted to receive urine. The tubular member is positionable within a lower urinary tract such that the reversibly expandable element operatively engages a structure of the lower urinary tract so as to prevent migration of the prosthesis so positioned. The reversibly expandible element is in non-reversible fluid communication with the tubular element for selective expansion thereof, the reversibly expandible element is further operatively engagable so as to discharge fluid non-reversibly received from the tubular member exterior to same.
摘要翻译：为具有较低尿路症状（LUTS）或尿潴留的患者提供内尿道假体，组装和伴随方法的若干实施例。内尿道假体包括可逆地扩张的元件，其沿着适于接收尿液的管状构件周向地纵向设置。管状构件可定位在下尿路内，使得可逆扩张的元件可操作地接合下尿道的结构，以便防止如此定位的假体的移动。可逆膨胀元件与管状元件不可逆地流体连通，用于其选择性膨胀，可逆膨胀元件进一步可操作地接合，从而将外部不可逆地从管状构件接收的流体排出到外部。

10. 发明授权

US07048698B2 Urethral profiling device and methodology 有权
标题翻译：尿道造影装置和方法论
公开(公告)号：US07048698B2
公开(公告)日：2006-05-23
申请号：US10179108
申请日：2002-06-24
申请人： Mark J. Whalen , Lloyd K. Willard , John M. Reid
发明人： Mark J. Whalen , Lloyd K. Willard , John M. Reid
IPC分类号： A61B51/03
CPC分类号： A61B5/1076 , A61M29/02 , A61M2025/0004 , A61M2205/3331 , A61M2210/1096
摘要： A urethral profile apparatus, assembly and appurtenant methodology is provided. The apparatus includes an elongate member having proximal and distal ends, the proximal end including a probe. The probe is selectively positionable within a urethral passageway by axial translation of the elongate member via the distal end, with the probe dimensioned so as to indicate constrictures of the urethral passageway.
摘要翻译：提供尿道剖面装置，装配和附属方法。该装置包括具有近端和远端的细长构件，近端包括探针。通过经由远端的细长构件的轴向平移，探针可选择性地定位在尿道通道内，探针的尺寸设定为指示尿道通道的结构。

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