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1. 发明申请

US20060015184A1 Stacking implants for spinal fusion 审中-公开
标题翻译：堆叠植入物进行脊柱融合
公开(公告)号：US20060015184A1
公开(公告)日：2006-01-19
申请号：US11047982
申请日：2005-01-31
申请人： John Winterbottom , Ryan Belaney , David Knaack , Todd Boyce , Lawrence Shimp , Samuel Lee , David Kaes , Marc Burel
发明人： John Winterbottom , Ryan Belaney , David Knaack , Todd Boyce , Lawrence Shimp , Samuel Lee , David Kaes , Marc Burel
IPC分类号： A61F2/30
CPC分类号： A61L27/3608 , A61F2/28 , A61F2/3094 , A61F2/44 , A61F2/4455 , A61F2002/2817 , A61F2002/2835 , A61F2002/30062 , A61F2002/3008 , A61F2002/30092 , A61F2002/3023 , A61F2002/30261 , A61F2002/30387 , A61F2002/30405 , A61F2002/30426 , A61F2002/30433 , A61F2002/30448 , A61F2002/305 , A61F2002/3055 , A61F2002/30556 , A61F2002/30599 , A61F2002/30616 , A61F2002/30828 , A61F2002/30841 , A61F2002/3085 , A61F2002/30879 , A61F2002/30892 , A61F2002/30904 , A61F2002/4475 , A61F2210/0004 , A61F2210/0014 , A61F2220/0025 , A61F2220/0041 , A61F2220/005 , A61F2230/0069 , A61F2230/0082 , A61F2250/0009 , A61F2250/0063 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179 , A61F2310/00359 , A61F2310/00365 , A61F2310/00377 , A61L27/3658 , A61L27/44 , A61L27/46 , A61L27/58 , A61L2430/38
摘要： An implant system for fusing vertebrae includes a variety of shapes that may be stacked to accommodate different intervertebral spacings and curvatures. The implants comprise polymer-bone composites that have osteogenic properties. By selection of an appropriate set of shapes, the surgeon can tailor the overall shape of the implant before or during surgery, in order to best match the shape of the intervertebral cavity for a particular patient.
摘要翻译：用于融合椎骨的植入系统包括可以被堆叠以适应不同椎间间隙和曲率的各种形状。植入物包含具有成骨性质的聚合物 - 骨复合材料。通过选择适当的形状集，外科医生可以在手术之前或手术期间定制植入物的整体形状，以便最佳地匹配特定患者的椎间孔的形状。

2. 发明申请

US20050251267A1 Cell permeable structural implant 审中-公开
标题翻译：细胞渗透性结构植入物
公开(公告)号：US20050251267A1
公开(公告)日：2005-11-10
申请号：US11047992
申请日：2005-01-31
申请人： John Winterbottom , Ryan Belaney , David Knaack , Todd Boyce , Lawrence Shimp , Samuel Lee , David Kaes
发明人： John Winterbottom , Ryan Belaney , David Knaack , Todd Boyce , Lawrence Shimp , Samuel Lee , David Kaes
IPC分类号： A61F2/00 , A61F2/02 , A61F2/28 , A61F2/30 , A61F2/46 , C12N5/08
CPC分类号： A61F2/28 , A61F2/4644 , A61F2002/30062 , A61F2002/3093 , A61F2002/4645 , A61F2210/0004 , A61F2310/00179
摘要： An implant including a cell conducting phase and a binder phase. At least a portion of the surface of the implant includes the cell conducting phase, and the cell conducting phase defines a path from the surface of the implant to an interior of the implant.
摘要翻译：包括细胞传导相和粘结相的植入物。植入物的表面的至少一部分包括细胞传导相，并且细胞传导相限定从植入物表面到植入物内部的路径。

3. 发明申请

US20070265537A1 METHOD AND SYSTEM FOR REAL-TIME DIGITAL FILTERING FOR ELECTROPHYSIOLOGICAL AND HEMODYNAMIC AMPLIFERS 有权
标题翻译：用于电生理和动力放大器的实时数字滤波的方法和系统
公开(公告)号：US20070265537A1
公开(公告)日：2007-11-15
申请号：US11467361
申请日：2006-08-25
申请人： Samuel Lee , Joel Q. Xue
发明人： Samuel Lee , Joel Q. Xue
IPC分类号： A61B5/04
CPC分类号： A61B5/04017 , A61B5/042 , A61B5/0432 , A61N1/3704
摘要： The present invention includes a method and system for real-time digital filtering for electrophysiological and hemodynamic amplifiers. The invention replaces the analog circuits currently used for signal filtering and conditioning in such systems with digital filters that may be implemented in a software application. The method and system includes digitizing the analog signal collected from the patient prior to performing the signal filtering and conditioning. The method and system also includes removing stimulus artifacts, as well as performing sample rate conversion and scaling on the digital signal. The processed digital signals may be used, displayed, saved and converted to analog signal thru digital-to-analog conversion.
摘要翻译：本发明包括用于电生理和血液动力学放大器的实时数字滤波的方法和系统。本发明用可在软件应用中实现的数字滤波器代替目前在这种系统中用于信号滤波和调理的模拟电路。所述方法和系统包括在执行信号过滤和调理之前数字化从患者收集的模拟信号。该方法和系统还包括去除刺激伪影，以及对数字信号执行采样率转换和缩放。经处理的数字信号可以通过数模转换使用，显示，保存并转换为模拟信号。

4. 发明申请

US20080255569A1 Bone support device, system, and method 审中-公开
标题翻译：骨支持装置，系统和方法
公开(公告)号：US20080255569A1
公开(公告)日：2008-10-16
申请号：US11713771
申请日：2007-03-02
申请人： Andrew Kohm , Janna Clark , Samuel Lee , Thomas A. Slater
发明人： Andrew Kohm , Janna Clark , Samuel Lee , Thomas A. Slater
IPC分类号： A61B17/58 , A61M29/00 , A61F2/44
CPC分类号： A61B17/7098 , A61B90/39 , A61B2017/00867
摘要： A bone support and/or barrier device, system, kit, and method can include an implantable structure having an outer surface, an inner surface, a first bone contact portion, and a second bone contact portion. The structure can be collapsible to an undeployed configuration capable of percutaneous insertion to the interior of a bone and expandable to a deployed configuration in the bone. In the deployed configuration, the first bone contact portion can contact a first portion of the bone, and the second bone contact portion can contact a second portion of the bone such that a load placed on the first portion of the bone can be transferred through the implantable structure to the second portion of the bone. The implantable structure can include a barrier material adapted to restrict a bone filler material inserted into the bone adjacent the inner surface of the structure from flowing to the outer surface of the structure.
摘要翻译：骨支撑和/或阻挡装置，系统，试剂盒和方法可以包括具有外表面，内表面，第一骨接触部分和第二骨接触部分的可植入结构。该结构可以折叠成能够经皮插入到骨骼内部并且可扩展到骨中部署构型的未部署构型。在所展开的构造中，第一骨接触部分可以接触骨的第一部分，并且第二骨接触部分可以接触骨的第二部分，使得放置在骨的第一部分上的负载可以通过可植入结构到骨的第二部分。可植入结构可以包括阻挡材料，该阻挡材料适于限制插入邻近结构的内表面的骨中的骨填充材料流入结构的外表面。

5. 发明申请

US20060133579A1 Distortion corrector for digital radiograph 审中-公开
标题翻译：数字射线照相变形矫正器
公开(公告)号：US20060133579A1
公开(公告)日：2006-06-22
申请号：US11012992
申请日：2004-12-16
申请人： Samuel Lee , Michael Kwon , Grace Lee
发明人： Samuel Lee , Michael Kwon , Grace Lee
IPC分类号： A61B6/14 , G03B42/02 , G03C5/16
CPC分类号： G03B42/02 , A61B5/1075 , A61B5/4547 , A61B6/14 , G03C11/02
摘要： A dental X-ray image sensor provided with a cross mark that is opaque to radio waves on the corner of a digital radiography sensor surface renders a computer program to recognize true dimension and to rescale any distortion due to angulational position error in a conventional X-ray digital radiograph system.
摘要翻译：具有对数字射线照相传感器表面的角落上的无线电波不透明的十字标记的牙科X射线图像传感器使得计算机程序能够识别真实的尺寸，并且在常规的X射线图像传感器表面中， ray数字射线照相系统。

6. 发明申请

US20080075788A1 DIAMMONIUM PHOSPHATE AND OTHER AMMONIUM SALTS AND THEIR USE IN PREVENTING CLOTTING 审中-公开
标题翻译：磷酸氢二铵和其他钠盐及其在预防衣服中的用途
公开(公告)号：US20080075788A1
公开(公告)日：2008-03-27
申请号：US11859291
申请日：2007-09-21
申请人： Samuel Lee , Stephanie Louie , Jeffrey D. Schwardt , Thomas A. Slater , Robert Wenz
发明人： Samuel Lee , Stephanie Louie , Jeffrey D. Schwardt , Thomas A. Slater , Robert Wenz
IPC分类号： A61K31/04 , A61F2/06 , A61K33/42
CPC分类号： A61L24/001 , A61L17/12 , A61L33/0041
摘要： The present invention relates to products, methods, and processes of various ammonium salts and their use as anti-coagulants.
摘要翻译：本发明涉及各种铵盐的产品，方法和方法及其作为抗凝剂的用途。

7. 发明授权

US09107951B2 Calcium particle-embedded, snap-to-dough, high-viscosity bone cement 有权
标题翻译：钙颗粒嵌入，咬合面团，高粘度骨水泥
公开(公告)号：US09107951B2
公开(公告)日：2015-08-18
申请号：US13812364
申请日：2011-07-26
申请人： Samuel Lee , Joerg Meyer , Robert Wenz , Thomas A Slater , Ann M. Heike
发明人： Samuel Lee , Joerg Meyer , Robert Wenz , Thomas A Slater , Ann M. Heike
IPC分类号： C08L33/12 , A61L24/02 , A61K47/32 , A61L24/04 , A61K9/14 , A61L24/00 , A61L24/06
CPC分类号： A61K47/32 , A61L24/0015 , A61L24/02 , A61L24/043 , A61L24/06 , A61L2300/252 , A61L2300/402 , A61L2300/406 , A61L2300/414 , A61L2300/416 , A61L2300/44 , A61L2300/442 , A61L2430/02 , C08L33/12
摘要： The present invention relates to a composition comprising: a) a first component comprising a poly(methyl met 5 hacrylate) (PMMA), a contrast agent, a radical donor and calcium based particles; and b) a second component comprising methyl methacrylate (MMA), a radical scavenger, and a polymerization accelerator; wherein the composition has an average setting time of about 13 minutes.
摘要翻译：本发明涉及一种组合物，其包含：a）包含聚（甲基甲基丙烯酸甲酯）（PMMA），造影剂，自由基供体和钙基颗粒的第一组分; 和b）包含甲基丙烯酸甲酯（MMA），自由基清除剂和聚合促进剂的第二组分; 其中所述组合物具有约13分钟的平均凝固时间。

8. 发明授权

US08608696B1 Rapid fluid cooling devices and methods for cooling fluids 失效
标题翻译：快速流体冷却装置和冷却流体的方法
公开(公告)号：US08608696B1
公开(公告)日：2013-12-17
申请号：US12711749
申请日：2010-02-24
申请人： Andrew J. DiMeo , Nathan M. Cox , Steven P. Grove , Samuel Lee , Luke D. Oltmans , Kathryn H. Sauer
发明人： Andrew J. DiMeo , Nathan M. Cox , Steven P. Grove , Samuel Lee , Luke D. Oltmans , Kathryn H. Sauer
IPC分类号： A61F7/12
CPC分类号： A61M5/44 , A61F7/0085 , A61F7/106 , A61F2007/0276 , A61M2202/04 , A61M2205/3606 , A61M2205/364 , F25D5/00
摘要： A cooling device includes a target fluid inlet, a target fluid outlet, an inner conduit, and a chamber surrounding the inner conduit. The inner conduit communicates with the target fluid inlet and the target fluid outlet, and provides a flow path for a target fluid to be cooled. The chamber contains a first endothermic reactant and includes a reactant inlet selectively alterable from a closed state to an open state. When the reactant inlet is in the closed state, the first endothermic reactant is isolated from a second endothermic reactant and no endothermic reaction occurs. When the reactant inlet is in the open state, the reactant inlet provides a flow path for enabling the second endothermic reactant to come into contact with the first endothermic reactant in the chamber for initiating the endothermic reaction and cooling the target fluid in the inner conduit.
摘要翻译：冷却装置包括目标流体入口，目标流体出口，内部导管和围绕内部导管的室。内部导管与目标流体入口和目标流体出口连通，并为待冷却的目标流体提供流动路径。该室包含第一吸热反应物并且包括可选择性地从关闭状态改变到打开状态的反应物入口。当反应物入口处于关闭状态时，第一吸热反应物与第二吸热反应物分离，并且不发生吸热反应。当反应物入口处于打开状态时，反应物入口提供流路，使第二吸热反应物与腔室中的第一吸热反应物接触，用于引发吸热反应并冷却内管道中的目标流体。

9. 发明申请

US20130210960A1 CALCIUM PARTICLE-EMBEDDED, SNAP-TO-DOUGH, HIGH-VISCOSITY BONE CEMENT 有权
标题翻译：钙颗粒嵌入式，SNAP-DOUGH，高粘度骨水泥
公开(公告)号：US20130210960A1
公开(公告)日：2013-08-15
申请号：US13812364
申请日：2011-07-26
申请人： Samuel Lee , Joerg Meyer , Robert Wenz , Thomas A. Slater , Ann M. Heike
发明人： Samuel Lee , Joerg Meyer , Robert Wenz , Thomas A. Slater , Ann M. Heike
IPC分类号： A61K47/32
CPC分类号： A61K47/32 , A61L24/0015 , A61L24/02 , A61L24/043 , A61L24/06 , A61L2300/252 , A61L2300/402 , A61L2300/406 , A61L2300/414 , A61L2300/416 , A61L2300/44 , A61L2300/442 , A61L2430/02 , C08L33/12
摘要： The present invention relates to a composition comprising: a) a first component comprising a poly(methyl met 5 hacrylate) (PMMA), a contrast agent, a radical donor and calcium based particles; and b) a second component comprising methyl methacrylate (MMA), a radical scavenger, and a polymerization accelerator; wherein the composition has an average setting time of about 13 minutes.
摘要翻译：本发明涉及一种组合物，其包含：a）包含聚（甲基甲基丙烯酸甲酯）（PMMA），造影剂，自由基供体和钙基颗粒的第一组分; 和b）包含甲基丙烯酸甲酯（MMA），自由基清除剂和聚合促进剂的第二组分; 其中所述组合物具有约13分钟的平均凝固时间。

10. 发明授权

US08372115B2 Bone support device, system and method 有权
标题翻译：骨支撑装置，系统和方法
公开(公告)号：US08372115B2
公开(公告)日：2013-02-12
申请号：US13231738
申请日：2011-09-13
申请人： Andrew Kohm , Janna Clark , Samuel Lee , Thomas A. Slater
发明人： Andrew Kohm , Janna Clark , Samuel Lee , Thomas A. Slater
IPC分类号： A61B2/44
CPC分类号： A61B17/7098 , A61B90/39 , A61B2017/00867
摘要： A bone support and/or barrier device and having an implantable structure including an outer surface, an inner surface, a first bone contact portion, and a second bone contact portion. The structure is collapsible to an undeployed configuration capable of percutaneous insertion to the interior of a bone and expandable to a deployed configuration in the bone. In the deployed configuration, the first bone contact portion contacts a first portion of the bone, and the second bone contact portion contacts a second portion of the bone such that a load placed on the first portion of the bone is transferred through the implantable structure to the second portion of the bone. The implantable structure includes a barrier material adapted to restrict bone filler material inserted into the bone adjacent the inner surface of the structure from flowing to the outer surface of the structure. A method is also disclosed.
摘要翻译：骨支撑和/或阻挡装置，并且具有包括外表面，内表面，第一骨接触部分和第二骨接触部分的可植入结构。该结构可折叠到能够经皮插入到骨骼内部并且可扩展到骨中部署构型的未部署构型。在展开构造中，第一骨接触部分接触骨的第一部分，并且第二骨接触部分接触骨的第二部分，使得放置在骨的第一部分上的载荷通过可植入结构转移到骨的第二部分。可植入结构包括阻挡材料，该阻挡材料适于限制插入邻近结构的内表面的骨中的骨填充材料流入结构的外表面。还公开了一种方法。

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