专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070191963A1 INJECTABLE AND MOLDABLE BONE SUBSTITUTE MATERIALS 有权
标题翻译：可注射和可修复的骨代替材料
公开(公告)号：US20070191963A1
公开(公告)日：2007-08-16
申请号：US11625119
申请日：2007-01-19
申请人： John Winterbottom , David Kaes , Deger Tunc , Todd Boyce , David Knaack , James Russell , Subhabrata Bhattacharyya
发明人： John Winterbottom , David Kaes , Deger Tunc , Todd Boyce , David Knaack , James Russell , Subhabrata Bhattacharyya
IPC分类号： A61F2/28
CPC分类号： A61F2/28 , A61F2002/2835 , A61F2002/30062 , A61F2002/30677 , A61F2210/0004 , A61F2310/00293 , A61F2310/00359 , A61F2310/00365 , A61L27/446 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L2400/06 , A61L2400/08 , A61L2430/02
摘要： An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.
摘要翻译：一种植物复合材料，其包含多种无机材料颗粒，骨替代材料，骨衍生材料或其任何组合; 以及与颗粒结合的聚合物材料。复合材料可以自然地模塑或流动，或者它可以是可模制的或可设定的。植入后，可以将复合材料设置成为植入物提供机械强度。本发明的复合材料具有能够填充不规则形状的植入部位的优点，同时可设置为提供大多数矫形应用所需的机械强度。本发明还提供了使用和制备可模制和可流动的复合材料的方法。

2. 发明授权

US09107751B2 Injectable and moldable bone substitute materials 有权
标题翻译：注射成型骨替代材料
公开(公告)号：US09107751B2
公开(公告)日：2015-08-18
申请号：US11625119
申请日：2007-01-19
申请人： John Winterbottom , David R. Kaes , Deger C. Tunc , Todd M. Boyce , David Knaack , James Russell , Subhabrata Bhattacharyya
发明人： John Winterbottom , David R. Kaes , Deger C. Tunc , Todd M. Boyce , David Knaack , James Russell , Subhabrata Bhattacharyya
IPC分类号： A61K9/00 , A61F2/28 , A61L27/44 , A61L27/46 , A61F2/30
CPC分类号： A61F2/28 , A61F2002/2835 , A61F2002/30062 , A61F2002/30677 , A61F2210/0004 , A61F2310/00293 , A61F2310/00359 , A61F2310/00365 , A61L27/446 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L2400/06 , A61L2400/08 , A61L2430/02
摘要： An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.
摘要翻译：一种植物复合材料，其包含多种无机材料颗粒，骨替代材料，骨衍生材料或其任何组合; 以及与颗粒结合的聚合物材料。复合材料可以自然地模塑或流动，或者它可以是可模制的或可设定的。植入后，可以将复合材料设置成为植入物提供机械强度。本发明的复合材料具有能够填充不规则形状的植入部位的优点，同时可设置为提供大多数矫形应用所需的机械强度。本发明还提供了使用和制备可模制和可流动的复合材料的方法。

3. 发明授权

US08734525B2 Osteoinductive demineralized cancellous bone 有权
标题翻译：骨诱导软骨松质骨
公开(公告)号：US08734525B2
公开(公告)日：2014-05-27
申请号：US12140025
申请日：2008-06-16
申请人： Keyvan Behnam , Nanette Forsyth , James Russell , John Winterbottom , Todd Boyce
发明人： Keyvan Behnam , Nanette Forsyth , James Russell , John Winterbottom , Todd Boyce
IPC分类号： A61K35/32
CPC分类号： A61K35/32 , A61F2/28 , A61F2002/2817 , A61F2002/30059 , A61F2310/00359 , A61L27/3608 , A61L27/3641 , A61L27/3645 , A61L27/3683 , A61L27/3687 , A61L27/3691 , A61L27/3695 , A61L27/3878 , A61L2430/02
摘要： An osteoinductive demineralized bone matrix, corresponding osteoimplants, and methods for making the osteoinductive demineralized bone matrix are disclosed. The osteoinductive demineralized bone matrix may be prepared by providing demineralized bone and altering the collagenous structure of the bone. The osteoinductive demineralized bone matrix may also be prepared by providing demineralized bone and compacting the bone, for example via mechanical compaction, grinding into a particulate, or treatment with a chemical. Additives such as growth factors or bioactive agents may be added to the osteoinductive demineralized bone matrix. The osteoinductive demineralized bone matrix may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, may induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. The osteoinductive demineralized bone matrix may also be used as a delivery device to administer bioactive agents.
摘要翻译：公开了一种骨诱导的软骨骨架，相应的骨关节植入物以及用于制造骨诱导性软骨骨架的方法。可以通过提供软化骨和改变骨的胶原结构来制备骨诱导的软骨骨架。还可以通过提供脱矿质骨和压实骨，例如通过机械压实，研磨成颗粒或用化学品处理来制备骨诱导的软化骨基质。添加剂如生长因子或生物活性剂可以加入到骨诱导的软化骨基质中。骨诱导的骨质疏松骨质可形成成骨植骨。当植入植入哺乳动物体内的植骨植入物可能在植入物的位置诱导软骨内骨形成的完全发育级联，包括血管化，矿化和骨髓分化。骨诱导的软化骨基质也可以用作施用生物活性剂的递送装置。

4. 发明申请

US20070168030A1 Osteoimplant and Method for Making Same 有权
标题翻译：植骨及其制作方法
公开(公告)号：US20070168030A1
公开(公告)日：2007-07-19
申请号：US11676429
申请日：2007-02-19
申请人： Jean Edwards , Lawrence Shimp , Michele Diegmann , Todd Boyce , Nelson Scarborough , James Russell
发明人： Jean Edwards , Lawrence Shimp , Michele Diegmann , Todd Boyce , Nelson Scarborough , James Russell
IPC分类号： A61F2/28 , A61F2/44
CPC分类号： A61L27/3683 , A61L27/3608 , A61L27/365 , A61L2430/02
摘要： A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a depth of at least about 100 microns; and, configuring the monolithic section of cortical bone to provide an osteoimplant possessing an outer surface possessing at least one demineralized zone and a non-demineralized zone. An implant produced according to the above method demonstrates improved osteoinduction without producing any clinically significant reduction of strength in critical regions of the osteoimplant.
摘要翻译：提供了一种制造骨诱导性骨植入物的方法，其包括以下步骤：将至少一个皮质骨整体部分的至少一个表面的部分或全部软化至至少约100微米的深度; 以及配置皮质骨的整体部分以提供具有外表面的骨植入物，所述外表面具有至少一个脱矿质区和非脱矿质区。根据上述方法制备的植入物表现出改善的骨诱导，而不会在骨植入物的临界区域中产生任何临床显着的强度降低。

5. 发明公开

US20230383555A1 Scaffolding 审中-公开
公开(公告)号：US20230383555A1
公开(公告)日：2023-11-30
申请号：US18448892
申请日：2023-08-11
申请人： James Russell
发明人： James Russell
IPC分类号： E04G3/24 , E04G5/04 , E04G5/06
CPC分类号： E04G3/24 , E04G5/045 , E04G5/061 , E04G5/067 , E04G7/02
摘要： A scaffolding assembly adapted to be releasably attached to an elongate support member such as an overhead pipe. The scaffolding assembly has a split collar and a platform assembly adapted to be releasably attached to the split collar. The split collar comprises at least two segments which can encircle the pipe and be secured to one another. The platform assembly which includes a platform deck has a connector formation which extends laterally outwardly from the deck to an extent that it can engage a receiving formation on the collar assembly and thereby attach the platform assembly to the collar assembly.

6. 发明授权

US09962898B1 Method of manufacturing a bottom gusseted pouch 有权
公开(公告)号：US09962898B1
公开(公告)日：2018-05-08
申请号：US14854697
申请日：2015-09-15
申请人： James Russell , John Ferber
发明人： James Russell , John Ferber
IPC分类号： B31B49/04 , B31B37/00 , B31B23/00
CPC分类号： B31B37/00 , B31B23/00 , B31B70/00 , B31B70/10 , B31B70/262 , B31B70/8133 , B31B70/94 , B31B2155/0012 , B31B2160/10 , B31B2160/20 , B31B2170/20 , B31B2237/10 , B31B2237/20 , B31B2237/403 , B65D33/02 , B65D75/008
摘要： A method of manufacturing a bottom gusseted pouch is provided. The method comprises unwinding a pouch webbing in a first flow direction, the pouch webbing defining front and back panels; inserting a gusset webbing between the panels in a second flow direction; attaching the gusset webbing to the panels to form a bottom gusseted end; optionally inserting a closure mechanism between the panels in a third flow direction; attaching the closure mechanism to the panels to form the resealable top end of the pouch; sealing the side edges of the panels to complete the pouch; and optionally cutting the completed pouch from the pouch webbing. At least one of the pouch webbing and the gusset webbing is formed of a supported film.

7. 发明授权

US09371556B2 Solutions, methods and kits for deactivating nucleic acids 有权
标题翻译：用于灭活核酸的解决方案，方法和试剂盒
公开(公告)号：US09371556B2
公开(公告)日：2016-06-21
申请号：US11073085
申请日：2005-03-04
申请人： Norman C. Nelson , Kenneth A. Browne , Lizhong Dai , James Russell , Mark E. Filipowsky , Margarita B. Kaminsky , Daniel L. Kacian
发明人： Norman C. Nelson , Kenneth A. Browne , Lizhong Dai , James Russell , Mark E. Filipowsky , Margarita B. Kaminsky , Daniel L. Kacian
IPC分类号： C12Q1/68 , A61L2/18 , C11D3/395
CPC分类号： C12Q1/68 , A61L2/186 , C11D3/3956 , C12Q1/6848
摘要： The present invention relates to reagents for use in deactivating nucleic acids and methods of making and using the same.
摘要翻译：本发明涉及用于失活核酸的试剂及其制备和使用方法。

8. 发明申请

US20100123627A1 APPARATUS AND METHOD FOR DETERMINING SIGNAL QUALITY IN A GEOLOCATION SYSTEM 有权
标题翻译：用于确定地质系统信号质量的装置和方法
公开(公告)号：US20100123627A1
公开(公告)日：2010-05-20
申请号：US12547345
申请日：2009-08-25
申请人： Tim Reynolds , Shane McLeod , James Russell
发明人： Tim Reynolds , Shane McLeod , James Russell
IPC分类号： G01S3/02
CPC分类号： G01S5/06 , G01S5/021
摘要： In a geolocation system for determining a geolocation of a target emitter, a method for determining the geolocation. The method comprises receiving a signal transmitted from the target emitter at each one of a plurality of sensors; determining whether signals received at n sensors, from among the plurality of sensors, satisfy one or more threshold values related to a condition of the received signals; if signals received at n sensors satisfy the threshold value, commanding m of the n sensors to transmit the signal received thereat or information related to the signal received thereat to a processor; at the processor, determining time difference estimates for the m received signals and determining the geolocation of the target emitter from the time difference estimates.
摘要翻译：在用于确定目标发射器的地理位置的地理定位系统中，确定地理位置的方法。该方法包括在多个传感器中的每一个处接收从目标发射器发送的信号; 确定在所述多个传感器中从n个传感器接收的信号是否满足与所接收的信号的条件相关的一个或多个阈值; 如果在n个传感器处接收的信号满足阈值，则命令m个传感器将其上接收到的信号或与其上接收的信号有关的信息发送到处理器; 在处理器处，确定m个接收信号的时间差估计，并根据时间差估计确定目标发射器的地理位置。

9. 发明申请

US20090148458A1 COAGULATION FACTOR III POLYMORPHISMS ASSOCIATED WITH PREDICTION OF SUBJECT OUTCOME AND RESPONSE TO THERAPY 审中-公开
标题翻译：凝血因子III多态性与预测受试者的预后和治疗反应
公开(公告)号：US20090148458A1
公开(公告)日：2009-06-11
申请号：US12090613
申请日：2006-06-23
申请人： James Russell , Keith R. Walley
发明人： James Russell , Keith R. Walley
IPC分类号： A61K39/395 , C12Q1/68 , C07H21/04 , C07K2/00 , A61K38/16
CPC分类号： C07K14/745 , C07K14/70596 , C12Q1/6883 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156 , C12Q2600/172
摘要： The invention provides methods and kits for obtaining a prognosis for a subject having or at risk of developing an inflammatory condition or hypertension. The method generally comprises determining a coagulation factor III genotype(s) of a subject for one or more SNPs, comparing the determined genotype with known genotypes for the polymorphism that correspond with the ability of the subject to recover from the inflammatory condition and identifying subjects based on their prognosis. The invention also provides for methods of identifying potential subjects having an inflammatory condition who are more likely to benefit from treatment with an anti-inflammatory agent or anti-coagulant agent and subsequent to treatment recover from the inflammatory condition. The invention also provides for methods of treating such subjects with an anti-inflammatory agent or anti-coagulant agent based on the subject's genotype.
摘要翻译：本发明提供了获得具有发展为炎症性或高血压风险的受试者的预后的方法和试剂盒。该方法通常包括确定一个或多个SNP的受试者的凝血因子III基因型，将确定的基因型与已知基因型与多态性相对应，所述多态性与受试者从炎性病症恢复的能力相符合并鉴定受试者对他们的预后。本发明还提供了鉴定潜在受试者的方法，所述潜在受试者具有更可能受益于用抗炎剂或抗凝血剂治疗并且随后治疗从炎症状态恢复的炎性病症。本发明还提供了基于受试者的基因型用抗炎剂或抗凝血剂治疗这些受试者的方法。

10. 发明申请

US20070281300A1 Thrombomodulin (Thbd) Haplotypes Predict Outcome 审中-公开
标题翻译：血栓调节素（Thbd）单倍型预测结果
公开(公告)号：US20070281300A1
公开(公告)日：2007-12-06
申请号：US10591325
申请日：2005-03-04
申请人： James Russell , Keith Walley
发明人： James Russell , Keith Walley
IPC分类号： C12Q1/68 , C07H21/02 , C07H21/04
CPC分类号： C12Q1/6883 , C12Q2600/118 , C12Q2600/156 , C12Q2600/172
摘要： The invention provides methods and kits for obtaining a prognosis for a subject having or at risk of developing an inflammatory condition. The method generally comprises determining a thrombomodulin genotype(s) of a subject for one or more SNPs, comparing the determined genotype with known genotypes for the polymorphism that correspond with the ability of the subject to recover from the inflammatory condition and identifying subjects based on their prognosis.
摘要翻译：本发明提供了用于获得具有或具有发展炎性病症风险的受试者的预后的方法和试剂盒。该方法通常包括确定一个或多个SNP的受试者的血栓调节蛋白基因型，将确定的基因型与已知基因型与多态性的已知基因型进行比较，所述基因型与受试者从炎性病症恢复的能力相对应，并基于它们鉴别受试者预后。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式