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1. 发明授权

US06805865B1 Compositions and methods for treating cancer and hyperproliferative disorders 失效
标题翻译：用于治疗癌症和过度增殖性疾病的组合物和方法
公开(公告)号：US06805865B1
公开(公告)日：2004-10-19
申请号：US09266543
申请日：1999-03-11
申请人： John W. Holaday , Antonio Ruiz , John Madsen , Stacy M. Plum
发明人： John W. Holaday , Antonio Ruiz , John Madsen , Stacy M. Plum
IPC分类号： A61K39395
CPC分类号： A61K39/0005 , A61K9/127 , A61K38/00 , A61K39/0011 , A61K2039/5258 , A61K2039/55555 , C07K16/22
摘要： Compositions and methods effective for eliciting an immune response for inhibiting abnormal or undesirable cell proliferation, particularly endothelial cell proliferation and angiogenesis related to neovascularization and tumor growth are provided. The compositions comprise a naturally occurring or synthetic protein, peptide, or protein fragment containing all or an active portion of a growth factor in a pharmaceutically acceptable carrier. The preferred growth factors comprise basic fibroblast growth factor and vascular endothelial growth factor. The methods involve administering to a human or animal the compositions described herein in a dosage sufficient to elicit an- immune response. The methods are useful for treating diseases and processes mediated by undesired and uncontrolled cell proliferation, such as cancer, particularly where uncontrolled cell proliferation is influenced by the presence of growth factors. Administration of the composition to a human or animal having metastasized tumors is useful for preventing the growth or expansion of such tumors.
摘要翻译：提供了有效地引发用于抑制异常或不期望的细胞增殖的免疫应答的组合物和方法，特别是与新生血管形成和肿瘤生长相关的内皮细胞增殖和血管生成。组合物包含在药学上可接受的载体中含有生长因子的全部或活性部分的天然存在或合成的蛋白质，肽或蛋白质片段。优选的生长因子包括碱性成纤维细胞生长因子和血管内皮生长因子。所述方法包括以足以引发免疫应答的剂量向人或动物施用本文所述的组合物。该方法可用于治疗由不期望的和不受控制的细胞增殖如癌症介导的疾病和过程，特别是在不受控制的细胞增殖受生长因子的存在影响的情况下。向具有转移性肿瘤的人或动物施用组合物可用于预防这种肿瘤的生长或扩增。

2. 发明授权

US06343319B1 Method and system for curriculum delivery 失效
标题翻译：课程交付的方法和系统
公开(公告)号：US06343319B1
公开(公告)日：2002-01-29
申请号：US09478695
申请日：2000-01-06
申请人： Daniel Abensour , Antonio Ruiz
发明人： Daniel Abensour , Antonio Ruiz
IPC分类号： G06F1516
CPC分类号： H04N21/8586 , G09B5/00 , H04N7/17318 , H04N21/235 , H04N21/23617 , H04N21/435 , H04N21/4622 , H04N21/4782
摘要： A computerized curriculum capture, organization and delivery system and method are provided, includes a data gathering mechanism for defining and downloading a quantity of data from a data source; a data retaining mechanism in communication with the data gathering mechanism for storing the quantity of data; a data organizing mechanism in communication with the data retaining mechanism for organizing the quantity of data into a cohesive and interactive lesson; a server in communication with the data retaining mechanism; a data delivery mechanism in communication with the server; and a user receiver with an input mechanism in communication with the server for operation by an end user; so that the data gathering mechanism defines and downloads a quantity of data from the data source pertaining to a selected curriculum topic, whereupon the data organizing mechanism partitions the data into curriculum units and arranges and interlinks the curriculum units into a lesson web having an interactive format; the server delivers the quantity of data to the data delivery mechanism and the data delivery mechanism delivers the quantity of data to the receiver in interactively accessible segments, and the data delivery mechanism and server deliver commands input into the end user receiver input mechanism to the data storage mechanism in a continuing interactive pattern.
摘要翻译：提供计算机化的课程表，组织和交付系统和方法，包括用于从数据源定义和下载数量的数据收集机制; 与数据收集机构通信的用于存储数据量的数据保持机构; 与数据保留机制通信的数据组织机构，用于将数据量组织成一个内聚和互动的课程; 与数据保持机制通信的服务器; 与服务器通信的数据传送机制; 以及具有与服务器通信的输入机构用于由最终用户操作的用户接收器; 使得数据收集机制从与所选择的课程主题相关的数据源定义并下载数量的数据，由此数据组织机构将数据分成课程单元，并将课程单元布置和互连到具有交互格式的课程网络 ; 服务器将数据量传送到数据传送机制，数据传送机制将数据量传送到交互可访问的段中的接收者，数据传送机制和服务器将输入到最终用户接收机输入机制的命令传递给数据存储机制以持续的交互模式。

3. 发明授权

US5666383A Variable rate discrete multiple tone bidirectional transmission 失效
标题翻译：可变速率离散多音双向传输
公开(公告)号：US5666383A
公开(公告)日：1997-09-09
申请号：US643443
申请日：1996-05-08
申请人： Kung-Shiuh Huang , Steven Peter Monti , Antonio Ruiz
发明人： Kung-Shiuh Huang , Steven Peter Monti , Antonio Ruiz
IPC分类号： G06F13/00 , H04J11/00 , H04L27/26 , H04L29/08 , H04K1/10 , H04L27/28
CPC分类号： H04L27/2608
摘要： This invention provides a method and apparatus for providing easily adaptable and select transmission and reception rates between a number of clients and a server. With this invention a broadband signal is transmitted/received from the server to the clients, who individually may need to receive/transmit only a small portion of the composite signal. More specifically, this invention uses discrete multiple tone coding to provide the easily adaptable and selected transmission rates to the clients.
摘要翻译：本发明提供一种用于在多个客户端和服务器之间提供容易适应和选择传输和接收速率的方法和装置。利用本发明，从服务器向客户端发送/接收宽带信号，客户端单独可能仅需要接收/发送复合信号的一小部分。更具体地，本发明使用离散多音调编码来向客户端提供易于适应和选择的传输速率。

4. 发明申请

US20070130876A1 Structural element for the construction of buildings 失效
标题翻译：建筑物结构要素
公开(公告)号：US20070130876A1
公开(公告)日：2007-06-14
申请号：US10583325
申请日：2004-12-17
申请人： Antonio Ruiz
发明人： Antonio Ruiz
IPC分类号： E04F13/04 , E04C3/30 , E04B1/18 , E04B1/16
CPC分类号： E04C3/09 , E04C5/04 , E04C2003/0473
摘要： A structural element for the construction of any type of buildings, comprising a first “C”-shaped element with equidistant cavities at least on one of its faces and a second element in the shape of a continuous strip with equidistant angular folds, whereby once both structural elements are assembled to each other, the angular folds of the metallic strip are projected through the cavities of the “C”-shaped structural element.
摘要翻译：用于构造任何类型的建筑物的结构元件，包括具有至少在其一个面上的等距空腔的第一“C”形元件和具有等距角度折叠的连续条带形状的第二元件，由此一旦两者结构元件彼此组装，金属带的角折叠通过“C”形结构元件的空腔突出。

5. 发明授权

US06945573B2 Externally adjustable latch 失效
标题翻译：外部可调闩锁
公开(公告)号：US06945573B2
公开(公告)日：2005-09-20
申请号：US10404172
申请日：2003-04-01
申请人： Antonio Ruiz , Braskel Elmer Phillips
发明人： Antonio Ruiz , Braskel Elmer Phillips
IPC分类号： B64D29/06 , E05B15/04 , E05B63/00 , E05B65/00 , E05C3/04 , E05C5/00
CPC分类号： E05B65/006 , B64D29/06 , E05B63/0056 , E05B2015/0441 , E05C3/048 , Y10S292/60 , Y10T292/0887 , Y10T292/0913
摘要： The present disclosure envisions an externally controllable adjustment assembly which is carried on the bolt of a latch assembly. The externally controllable adjustment assembly is generally flush-mounted relative to the exterior surfaces of a corresponding panel and structure. A small access opening is provided to access the adjustment assembly so as to help maintain the aerodynamic design of the latch. The externally controllable adjustment assembly includes an adjuster which works with an adjuster body. An external force is applied by the adjuster to one end of the adjuster body to transfer forces to a plunger positioned at the opposite end of the adjuster body. Adjustment of the plunger helps to adjust the latching force of the latch on the structure. The present disclosure allows for controllable external adjustment as well as controllable preloading of the forces on the latch. The adjuster can be controllably preloaded by using a torque-wrench or torque measuring device to make adjustments to a desired level of force.
摘要翻译：本公开设想一种外部可控的调节组件，该组件承载在闩锁组件的螺栓上。外部可控的调节组件通常相对于相应面板和结构的外表面嵌入安装。提供小的进入开口以进入调节组件，以帮助保持闩锁的空气动力学设计。外部可调的调节组件包括与调节器主体一起工作的调节器。通过调节器将外力施加到调节器主体的一端以将力传递到位于调节器主体的相对端的柱塞。柱塞的调节有助于调整结构上的闩锁的锁定力。本公开允许可控的外部调节以及力在锁闩上的可控的预加载。调节器可以通过使用扭矩扳手或扭矩测量装置来可控地预加载，以调节所需的力水平。

6. 发明授权

US5515511A Hybrid digital/analog multimedia hub with dynamically allocated/released channels for video processing and distribution 失效
标题翻译：混合数字/模拟多媒体集线器，具有动态分配/释放的视频处理和分配通道
公开(公告)号：US5515511A
公开(公告)日：1996-05-07
申请号：US254201
申请日：1994-06-06
申请人： Tam M. Nguyen , Deepak Rana , Antonio Ruiz , Barry E. Willner
发明人： Tam M. Nguyen , Deepak Rana , Antonio Ruiz , Barry E. Willner
IPC分类号： H04L12/28 , H04L12/64 , H04L29/06 , H04J3/17
CPC分类号： H04L65/605 , H04L12/2856 , H04L12/2874 , H04L12/6418 , H04L29/06 , H04L65/4084 , H04L2012/6456 , H04L2012/6483 , H04L2012/6486 , H04L29/06027
摘要： A multimedia distribution network combines the flexibility of digital video and digital networks with the low cost, high bandwidth, and isochronous capabilities of analog video distribution. At the heart of the network is a hybrid digital/analog multimedia hub, called a C-box, which provides connectivity to digital networks, both local area and wide area, with the necessary video compression and decompression, composition engines for multiple video streams and analog/digital conversions of the multiple video streams for connectivity to an analog video distribution network for delivery to end user workstations. The C-box receives multiple compressed digital video streams, decompresses the video streams, converts the decompressed video streams to analog, and delivers the converted analog signals to workstations via an analog cable television (CATV) network. The amount of video processing (e.g., compression and decompression) power required is proportional to the number of active video streams instead of the number of attached end user workstations. The analog channels over which the converted analog signals are transmitted are dynamically allocated, and once the analog signals have been transmitted to a requesting client terminal, the channels are released for reuse.
摘要翻译：多媒体分发网络将数字视频和数字网络的灵活性与模拟视频分发的低成本，高带宽和同步功能相结合。网络的核心是混合数字/模拟多媒体集线器，称为C盒，它提供与数字网络（包括局域和广域）的连接，具有必要的视频压缩和解压缩，用于多个视频流的组合引擎，用于连接到模拟视频分配网络的多个视频流的模拟/数字转换，以传送到最终用户工作站。 C盒接收多个压缩数字视频流，解压缩视频流，将解压缩的视频流转换为模拟，并通过模拟有线电视（CATV）网络将转换的模拟信号传送到工作站。所需的视频处理量（例如，压缩和解压缩）的功率与活动视频流的数量成比例，而不是连接的最终用户工作站的数量。转换的模拟信号被传输的模拟通道被动态地分配，一旦模拟信号已被发送到请求客户终端，则信道被释放以供重用。

7. 发明申请

US20060203719A1 Method and apparatus for protection switching in virtual private networks 有权
公开(公告)号：US20060203719A1
公开(公告)日：2006-09-14
申请号：US11352606
申请日：2006-02-13
申请人： Dongsoo Kim , Antonio Ruiz , Dhadesugoor Vaman , Joonbum Byun
发明人： Dongsoo Kim , Antonio Ruiz , Dhadesugoor Vaman , Joonbum Byun
IPC分类号： H04J3/14
CPC分类号： H04L12/14 , H04L2012/5627 , H04L2012/5636 , H04L2012/5651 , H04Q11/0478
摘要： Protection switching of a virtual private network is provided whereby working VPN paths and protection VPN paths are defined. The working VPN path is monitored for increased data traffic and failures, and in response, data is switched from the working VPN path to the protection VPN path. The working VPN path is monitored for a return to proper functioning and normal data conditions, and data is then switched back from the protection VPN path to the working VPN path. Additionally, data capacity is managed through virtual bandwidth classes, and different classes of qualities of service are provided.

8. 发明授权

US06177930B1 System and method for enabling a user to move between cyclically transmitted image streams 失效
标题翻译：使用户能够在循环传输的图像流之间移动的系统和方法
公开(公告)号：US06177930B1
公开(公告)日：2001-01-23
申请号：US08825326
申请日：1997-03-28
申请人： Richard Chernock , Paolo Dettori , Milan Milenkovic , Antonio Ruiz
发明人： Richard Chernock , Paolo Dettori , Milan Milenkovic , Antonio Ruiz
IPC分类号： H04N7173
CPC分类号： H04N21/482 , H04N5/4401 , H04N5/44543 , H04N5/50 , H04N7/165 , H04N21/26266 , H04N21/2665 , H04N21/2668 , H04N21/443 , H04N21/4722 , H04N21/643 , H04N21/8586
摘要： An interactive presentation system receives a plurality of series of digital data segments (e.g., image frames), each series of digital data segments appearing at the video presentation system on a repetitive, cyclic basis. Each digital data segment includes a first data portion from which an image can be constructed and a second data portion which includes information relating to the image and further includes, if required, information which links an active area of the image to another data source. The system includes an interface for receiving the repetitively transmitted series of digital data segments and a switch for selecting at least one of the received series of digital data segments. A display presents an image that is constructed from the first data portion of a data segment that is included in a series of digital data segments. A processor is responsive to a user's selection of an active area on a displayed image to employ information from the second data portion that is associated with the displayed image to operate the switch to access another data source. The other data source can be another data segment, a video presentation, or an audio presentation. The video presentation system is operable without requiring a reverse channel for communications with the transmission head end.
摘要翻译：交互式呈现系统接收多个数字数据段（例如，图像帧）系列，每一系列数字数据段以重复的循环方式出现在视频呈现系统中。每个数字数据段包括可从其构造图像的第一数据部分和包括与图像相关的信息的第二数据部分，并且如果需要，还包括将图像的活动区域链接到另一数据源的信息。该系统包括用于接收重复发送的数字数据段的接口和用于选择所接收的一系列数字数据段中的至少一个的开关。显示器呈现由包括在一系列数字数据段中的数据段的第一数据部分构成的图像。处理器响应于用户对显示的图像上的活动区域的选择，以采用与所显示的图像相关联的来自第二数据部分的信息来操作切换器以访问另一数据源。另一数据源可以是另一数据段，视频呈现或音频呈现。视频呈现系统可操作而不需要用于与传输头端通信的反向信道。

9. 发明授权

US6047317A System and method for enabling a user to rapidly access images in cyclically transmitted image streams 失效
标题翻译：用于使用户能够快速地访问循环传输的图像流中的图像的系统和方法
公开(公告)号：US6047317A
公开(公告)日：2000-04-04
申请号：US825325
申请日：1997-03-28
申请人： Chatschik Bisdikian , Richard Chernock , Milan Milenkovic , Antonio Ruiz , Frank Schaffa
发明人： Chatschik Bisdikian , Richard Chernock , Milan Milenkovic , Antonio Ruiz , Frank Schaffa
IPC分类号： H04N21/2362 , H04N21/262 , H04N21/4728 , H04N7/14
CPC分类号： H04N21/26266 , H04H20/16 , H04N21/2362 , H04N21/4728
摘要： A video presentation system receives a plurality of series of digital data segments (e.g., image frames) that are cyclically transmitted, wherein certain of the digital data segments manifest a higher priority and are present in the form of plural, time-spaced copies during a series of the digital data segments. The system includes an interface for receiving the repetitively transmitted series of digital data segments and a switch for selecting at least one of the received series of digital data segments. A display presents an image that is constructed from a digital data segment that is selected by a user. By providing plural copies of higher priority digital data segments in each series, a reduction in image access time results when the user selects one of the higher priority digital data segments. A set-top box which serves as the receiver can also be provided with sufficient memory to buffer a certain number of the higher priority digital data segments.
摘要翻译：视频呈现系统接收循环地发送的多个数字数据段（例如，图像帧），其中某些数字数据段表现出较高的优先级，并且在一段时间间隔的复制形式中存在系列数字数据段。该系统包括用于接收重复发送的数字数据段的接口和用于选择所接收的一系列数字数据段中的至少一个的开关。显示器呈现由用户选择的数字数据段构建的图像。通过在每个系列中提供更高优先级的数字数据段的多个副本，当用户选择较高优先级的数字数据段之一时，导致图像访问时间的减少。用作接收机的机顶盒还可以具有足够的存储器来缓冲一定数量的较高优先级的数字数据段。

10. 发明授权

US5282199A Method and apparatus for interoperation of FDDI-I and FDDI-II networks 失效
标题翻译： FDDI-I和FDDI-II网络互操作的方法和装置
公开(公告)号：US5282199A
公开(公告)日：1994-01-25
申请号：US997795
申请日：1992-12-29
申请人： Louis P. Herzberg , Baiju V. Patel , Antonio Ruiz , Frank A. Schaffa , Marc H. Willebeek-LeMair
发明人： Louis P. Herzberg , Baiju V. Patel , Antonio Ruiz , Frank A. Schaffa , Marc H. Willebeek-LeMair
IPC分类号： H04L12/433 , H04L12/46 , H04L12/64 , H04J3/00 , H04J3/16
CPC分类号： H04L12/4637 , H04L12/433 , H04L12/6418 , H04L2012/6437 , H04L2012/6451 , H04L2012/6459
摘要： A method and apparatus allow the interoperability of a token ring packet data network managed by the timed-token protocol (FDDI-I) and a TDM network (FDDI-II) with a given bandwidth allocation assigned to the packet data timed-token protocol. Only a single token is used, and the delay and loss of packets which cannot be transmitted on account of limited bandwidth is reduced. The flow of packets into the slots of the communications ring following the TDM protocol is controlled by varying the amount of time in which the token is held by the interface between the two communication rings. That is, the time in which the token is held by the interface is a function of the number TDM slots allocated to the transmission of packet data.
摘要翻译：一种方法和装置允许由定时令牌协议（FDDI-I）和TDM网络（FDDI-II）管理的令牌环分组数据网络的互操作性，其中分配给分组数据定时令牌协议的给定带宽分配。仅使用单个令牌，并且减少了由于有限带宽而无法发送的分组的延迟和丢失。通过改变由两个通信环之间的接口保持令牌的时间量来控制分组到TDM协议之后的通信环的时隙中的分组流。也就是说，由接口保存令牌的时间是分配给分组数据的传输的TDM时隙的数量的函数。

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