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1. 发明授权

US06310260B1 Separation processes 有权
标题翻译：分离过程
公开(公告)号：US06310260B1
公开(公告)日：2001-10-30
申请号：US09526191
申请日：2000-03-15
申请人： John Nicholas Argyropoulos , Jeffrey Scott Kanel , Michael Leo Tulchinsky , David James Miller , Donald Lee Morrison , Paul Foley , David Robert Bryant , Ailene Gardner Phillips , Brian Michael Roesch , John Robert Briggs , Max Min Lee , John Michael Maher
发明人： John Nicholas Argyropoulos , Jeffrey Scott Kanel , Michael Leo Tulchinsky , David James Miller , Donald Lee Morrison , Paul Foley , David Robert Bryant , Ailene Gardner Phillips , Brian Michael Roesch , John Robert Briggs , Max Min Lee , John Michael Maher
IPC分类号： C07C4550
CPC分类号： C07C45/50 , C07B63/00 , Y02P20/582 , C07C47/02
摘要： This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more products from a continuously generated reaction product fluid comprising one or more unreacted reactants, a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more organophosphorus ligand degradation products, said one or more reaction byproducts, said one or more products, one or more polar solvents and one or more nonpolar solvents by phase separation wherein (i) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more products is expressed by a partition coefficient ratio Ef1 which is a value greater than about 2.5, (ii) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more organophosphorus ligand degradation products is expressed by a partition coefficient ratio Ef2 which is a value greater than about 2.5, and (iii) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more reaction byproducts is expressed by a partition coefficient ratio Ef3 which is a value greater than about 2.5.
摘要翻译：本发明涉及从连续生成的反应产物流体中分离一种或多种有机磷配体降解产物，一种或多种反应副产物和一种或多种产物，所述反应产物流体包含一种或多种未反应的反应物，金属 - 有机磷配体络合物催化剂，有机磷配体，所述一种或多种有机磷配体降解产物，所述一种或多种反应副产物，所述一种或多种产物，一种或多种极性溶剂和一种或多种非极性溶剂通过相分离，其中（i）极性相的选择性为相对于一种或多种产物的有机磷配体由分配系数比Ef1表示，分配系数比Ef1大于约2.5，（ii）有机磷配体的极性相对于一种或多种有机磷配体的选择性降解产物由分配系数比Ef2表示，该分配系数比Ef2是大于th的值约为2.5，和（iii）极性相对于一种或多种反应副产物的有机磷配体的选择性由分配系数比Ef3表示，该分配系数比Ef3是大于约2.5的值。

2. 发明授权

US06307110B1 Separation processes 有权
标题翻译：分离过程
公开(公告)号：US06307110B1
公开(公告)日：2001-10-23
申请号：US09526337
申请日：2000-03-15
申请人： John Nicholas Argyropoulos , Jeffrey Scott Kanel , Michael Leo Tulchinsky , David James Miller , Donald Lee Morrison , Paul Foley , David Robert Bryant , Ailene Gardner Phillips , Brian Michael Roesch , John Robert Briggs , Max Min Lee , John Michael Maher
发明人： John Nicholas Argyropoulos , Jeffrey Scott Kanel , Michael Leo Tulchinsky , David James Miller , Donald Lee Morrison , Paul Foley , David Robert Bryant , Ailene Gardner Phillips , Brian Michael Roesch , John Robert Briggs , Max Min Lee , John Michael Maher
IPC分类号： C07C4550
CPC分类号： C07C45/50 , C07B63/00 , Y02P20/582 , C07C47/02
摘要： This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more products from a continuously generated reaction product fluid comprising one or more unreacted reactants, a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more organophosphorus ligand degradation products, said one or more reaction byproducts, said one or more products, one or more nonpolar solvents and one or more polar solvents by phase separation wherein (i) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more products is expressed by a partition coefficient ratio Ef1which is a value greater than about 2.5, (ii) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more organophosphorus ligand degradation products is expressed by a partition coefficient ratio Ef2 which is a value greater than about 2.5, and (iii) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more reaction byproducts is expressed by a partition coefficient ratio Ef3 which is a value greater than about 2.5.
摘要翻译：本发明涉及从连续生成的反应产物流体中分离一种或多种有机磷配体降解产物，一种或多种反应副产物和一种或多种产物，所述反应产物流体包含一种或多种未反应的反应物，金属 - 有机磷配体络合物催化剂，有机磷配体，所述一种或多种有机磷配体降解产物，所述一种或多种反应副产物，所述一种或多种产物，一种或多种非极性溶剂和一种或多种极性溶剂通过相分离，其中（i）非极性相的选择性为相对于一种或多种产物的有机磷配体由分配系数比Ef1表示，分配系数比Ef1大于约2.5，（ii）非极性相对于有机磷配体相对于一种或多种有机磷配体降解的选择性产品由分配系数比Ef2表示，该分配系数比Ef2是一个很大的值（iii）非极性相对于一种或多种反应副产物对有机磷配体的选择性由分配系数比Ef3表示，该分配系数比Ef3是大于约2.5的值。

3. 发明授权

US06303830B1 Metal-ligand complex catalyzed processes 有权
标题翻译：金属 - 配体络合物催化方法
公开(公告)号：US06303830B1
公开(公告)日：2001-10-16
申请号：US09526638
申请日：2000-03-15
申请人： John Nicholas Argyropoulos , Jeffrey Scott Kanel , Michael Leo Tulchinsky , David James Miller , Donald Lee Morrison , Paul Foley , David Robert Bryant
发明人： John Nicholas Argyropoulos , Jeffrey Scott Kanel , Michael Leo Tulchinsky , David James Miller , Donald Lee Morrison , Paul Foley , David Robert Bryant
IPC分类号： C07C4550
CPC分类号： C07B63/00 , C07C67/58 , Y02P20/582 , C07C69/716
摘要： This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more formylester products from a reaction product fluid comprising one or more unreacted unsaturated ester reactants, a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more organophosphorus ligand degradation products, said one or more reaction byproducts, said one or more products, a polar solvent and a nonpolar solvent by phase separation wherein(i) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more products is expressed by a partition coefficient ratio Ef1 which is a value greater than about 2.5, (ii) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more organophosphorus ligand degradation products is expressed by a partition coefficient ratio Ef2 which is a value greater than about 2.5, and (iii) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more reaction byproducts is expressed by a partition coefficient ratio Ef3 which is a value greater than about 2.5.
摘要翻译：本发明涉及一种从包含一种或多种未反应的不饱和酯反应物，金属 - 有机磷配位体配合物催化剂，任选的一种或多种反应产物流体的反应产物流体中分离一种或多种有机磷配体降解产物，一种或多种反应副产物和一种或多种甲酰酯产物的方法所述一种或多种有机磷配体降解产物，所述一种或多种反应副产物，所述一种或多种产物，极性溶剂和非极性溶剂通过相分离，其中（i）极性相对于有机磷配体的选择性对于一种或多种产物，由分配系数比Ef1表示，该分配系数比Ef1大于约2.5，（ii）极性相对于一种或多种有机磷配体降解产物的有机磷配体的选择性为由大于约2.5的值的分配系数比Ef2表示，a d（iii）极性相对于一种或多种反应副产物的有机磷配体的选择性由分配系数比Ef3表示，该分配系数比Ef3是大于约2.5的值。

4. 发明授权

US06307108B1 Metal-ligand complex catalyzed processes 有权
标题翻译：金属 - 配体络合物催化方法
公开(公告)号：US06307108B1
公开(公告)日：2001-10-23
申请号：US09525651
申请日：2000-03-15
申请人： John Nicholas Argyropoulos , Jeffrey Scott Kanel , Michael Leo Tulchinsky , David James Miller , Donald Lee Morrison , Paul Foley , David Robert Bryant
发明人： John Nicholas Argyropoulos , Jeffrey Scott Kanel , Michael Leo Tulchinsky , David James Miller , Donald Lee Morrison , Paul Foley , David Robert Bryant
IPC分类号： C07C4550
CPC分类号： C07C227/08 , C07C67/347 , C07C67/58 , Y02P20/582 , C07C69/716 , C07C229/08
摘要： This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more formylester products from a reaction product fluid comprising one or more unreacted unsaturated ester reactants, a metal-organophoshorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more organophosphorus ligand degradation products, said one or more reaction byproducts, said one or more products, a nonpolar solvent and a polar solvent by phase separation wherein (i) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more products is expressed by a partition coefficient ratio Ef1 which is a value greater than about 2.5 (ii) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more organophosphorus ligand degradation products is expressed by a partition coefficient ratio Ef2 which is a value greater than about 2.5, and (iii) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more reaction byproducts is expressed by a partition coefficient ratio Ef3 which is a value greater than about 2.5.
摘要翻译：本发明涉及一种从包含一种或多种未反应的不饱和酯反应物，金属有机磷配体配合物催化剂的反应产物流体中分离一种或多种有机磷配体降解产物，一种或多种反应副产物和一种或多种甲酰酯产物的方法，所述一种或多种有机磷配体降解产物，所述一种或多种反应副产物，所述一种或多种产物，非极性溶剂和极性溶剂通过相分离，其中（i）所述非极性相对于所述有机磷配体的选择性对于一种或多种产物，通过分配系数比Ef1表示，该分配系数比Ef1是大于约2.5的值（ii）表示非极性相对于一种或多种有机磷配体降解产物的非极性相对于有机磷配体的选择性通过大于约2的值的分配系数比Ef2。 5，和（iii）非极性相对于有机磷配体相对于一种或多种反应副产物的选择性由分配系数比Ef3表示，该分配系数比Ef3是大于约2.5的值。

5. 发明授权

US06525143B2 Dendritic macromolecules for metal-ligand catalyzed processes 有权
公开(公告)号：US06525143B2
公开(公告)日：2003-02-25
申请号：US09991572
申请日：2001-11-16
申请人： Michael Leo Tulchinsky , David James Miller
发明人： Michael Leo Tulchinsky , David James Miller
IPC分类号： C08F840
CPC分类号： C08G83/003 , C07C45/50 , C07F9/65744 , C07F9/65746 , C08G79/04 , Y02P20/582 , C07C47/02
摘要： This invention relates to dendritic macromolecules and their use in metal-dendritic macroligand complex catalyzed processes, e.g., hydroformylation. The use of metal-dendritic macroligand complex catalysts in such processes facilitates the separation of desired product from catalyst, for example, by membrane filtration.

6. 发明授权

US06350819B1 Dendritic macromolecules for metal-ligand catalyzed processes 失效
标题翻译：树枝状大分子用于金属 - 配体催化过程
公开(公告)号：US06350819B1
公开(公告)日：2002-02-26
申请号：US09697837
申请日：2000-10-27
申请人： Michael Leo Tulchinsky , David James Miller
发明人： Michael Leo Tulchinsky , David James Miller
IPC分类号： C08F840
CPC分类号： C08G83/003 , C07C45/50 , C07F9/65744 , C07F9/65746 , C08G79/04 , Y02P20/582 , C07C47/02
摘要： This invention relates to dendritic macromolecules and their use in metal-dendritic macroligand complex catalyzed processes, e.g., hydroformylation. The use of metal-dendritic macroligand complex catalysts in such processes facilitates the separation of desired product from catalyst, for example, by membrane filtration.
摘要翻译：本发明涉及树枝状大分子及其在金属树枝状大孔穴状配合物催化方法中的应用，例如加氢甲酰化。在这样的方法中使用金属 - 树枝状大环内酯类复合催化剂有助于将所需产物与催化剂分离，例如通过膜过滤。

7. 发明授权

US06362367B1 Preparation of organic acids 失效
公开(公告)号：US06362367B1
公开(公告)日：2002-03-26
申请号：US09063675
申请日：1998-04-21
申请人： John Braithwaite , David Robert Bryant , David James Miller , John Earl Logsdon
发明人： John Braithwaite , David Robert Bryant , David James Miller , John Earl Logsdon
IPC分类号： C07C5121
摘要： This invention relates to a process for producing one or more organic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen-enriched air containing at least about 50% oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperature is preferably controlled to within about ±3° C. of a target temperature. The organic acids described herein is useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.

8. 发明授权

US07689546B2 Point of law search system and method 有权
标题翻译：法律搜索系统和方法
公开(公告)号：US07689546B2
公开(公告)日：2010-03-30
申请号：US11204993
申请日：2005-08-17
申请人： David James Miller , Harry R. Silver , Andrew L. Freisthler
发明人： David James Miller , Harry R. Silver , Andrew L. Freisthler
IPC分类号： G06F17/30
CPC分类号： G06F17/30646 , G06F17/30634 , G06F17/30672 , Y10S707/99933
摘要： A “More Like This Headnote” search relates online headnotes intelligently so that users have the means to retrieve related headnotes quickly and easily. This is achieved by using a tailored search type in the search engine, which is designed to handle the text of a headnote as a search string. Retrieval logic then presents the search results to the user in a “Virtual Digest” view comprising related headnotes and case materials, sorted by user-selected options.
摘要翻译： “更像这个头脑”搜索智能地联系在线头脑，以便用户能够快速方便地检索相关的头条。这通过在搜索引擎中使用定制的搜索类型来实现，该搜索引擎旨在将头文本作为搜索字符串来处理。检索逻辑然后在“虚拟摘要”视图中向用户呈现搜索结果，该视图包括用户选择的选项排序的相关头条和案例资料。

9. 发明授权

US5926811A Statistical thesaurus, method of forming same, and use thereof in query expansion in automated text searching 失效
标题翻译：统计词库，形成方法，以及在自动文本搜索中的查询扩展中的使用
公开(公告)号：US5926811A
公开(公告)日：1999-07-20
申请号：US616883
申请日：1996-03-15
申请人： David James Miller , Xin Allan Lu , John David Holt
发明人： David James Miller , Xin Allan Lu , John David Holt
IPC分类号： G06F17/30 , G06F17/21
CPC分类号： G06F17/30737 , Y10S707/917 , Y10S707/99933 , Y10S707/99934 , Y10S707/99935 , Y10S707/99937
摘要： A statistical thesaurus is built dynamically, from the same text collection that is being searched, allowing improved generation of expanded query terms. The thesaurus is dynamic in that thesaurus records are collected, ranked, accessed, and applied dynamically. Thesaurus "records" are actually formed as indexed documents arranged in "collections". The collections are preferably distinguished based on text source (court cases versus news wires versus patents, and so forth). Each record has terms assembled in indexed groups (or segments) which inherently reflect a ranking based on relevance to an initial query. After an initial query is received, the appropriate collection(s) of records may be searched by a conventional search and retrieval engine, the searches inherently returning records ranked by degree of relevance due to the record indexing scheme. A record ranking scheme avoids contamination of relevant records by less relevant records. The record selection and the expansion query term generation processes are each divided into parallel threads. The separate threads correspond to respective text sources to enable the improved expansion query term generation to be provided in real time.
摘要翻译：统计词库是从正在搜索的相同文本集合中动态构建的，允许改进扩展查询词的生成。词库是动态的，因为词典记录被收集，排序，访问和动态应用。词典“记录”实际上是作为“集合”中排列的索引文档形成的。收藏品最好根据文本来源（法庭案件与新闻线对专利等）区分开来。每个记录都有汇编在索引组（或分段）中的条款，这些组根据初始查询的相关性固有地反映排名。在接收到初始查询之后，可以通过常规搜索和检索引擎来搜索适当的记录集合，由于记录索引方案，搜索本质上返回由相关程度排列的记录。记录排名计划避免相关记录的污染较少相关记录。记录选择和扩展查询项生成过程分为并行线程。单独的线程对应于相应的文本源，以使实时地提供改进的扩展查询词生成。

10. 发明授权

US08849789B2 System and method for searching for documents 有权
标题翻译：用于搜索文件的系统和方法
公开(公告)号：US08849789B2
公开(公告)日：2014-09-30
申请号：US13612477
申请日：2012-09-12
申请人： Ronald J. Meyer , Richard Ainsworth , Andrew Freisthler , Zachary W. Bennett , Mark C. Stiver , Jason Calton , Narasimha R. Edala , David James Miller , Donald Loritz
发明人： Ronald J. Meyer , Richard Ainsworth , Andrew Freisthler , Zachary W. Bennett , Mark C. Stiver , Jason Calton , Narasimha R. Edala , David James Miller , Donald Loritz
IPC分类号： G06F17/30
CPC分类号： G06F17/30867
摘要： A computer system is disclosed. The computer system includes one or more processors, and a memory storage storing one or more instructions for implementing a search tool. The instructions, when executed, instruct the computer system to perform a set of steps. The steps include receiving a search query from a user computer, the search query including one or more search terms to use to perform a first search. The steps further include, based on the one or more search terms, performing the first search, and providing for display at the user computer a list of one or more law-related documents responsive to the search query, a list of one or more recommended sources in which to perform a second search for documents, and a list of legal topics associated with the responsive documents.
摘要翻译：公开了一种计算机系统。计算机系统包括一个或多个处理器，以及存储用于实现搜索工具的一个或多个指令的存储器存储器。指令执行时，指示计算机系统执行一组步骤。所述步骤包括从用户计算机接收搜索查询，所述搜索查询包括用于执行第一搜索的一个或多个搜索词。所述步骤还包括基于所述一个或多个搜索术语执行所述第一搜索，并且在所述用户计算机上提供响应于所述搜索查询的一个或多个法律相关文档的列表，一个或多个推荐的列表执行第二次搜索文档的来源以及与响应文档相关联的法律主题列表。

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