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    • 2. 发明授权
    • Radially expandable tape-reinforced vascular grafts
    • 径向扩张带状血管移植物
    • US06863686B2
    • 2005-03-08
    • US09912006
    • 2001-07-24
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • A61F2/06B29D23/00B65B57/14B65G47/31
    • B29D23/001A61F2/06B65B57/14B65G47/31Y10T428/1328Y10T428/1352
    • A tape-reinforced tubular vascular graft formed of sintered fluoropolymer(s), such as expanded, sintered PTFE. The graft includes a base graft and a reinforcing tape applied thereto. The tape may be spirally wrapped about the graft or spirally wrapped into a tube about a cylindrical mandrel and then applied to the exterior of The graft. Radial shrinkage of the combined base graft and tape, or of the reinforcing tape tube, renders the vascular graft subsequently radially enlargeable by more than 5%, without tearing or breaking of the reinforcement tape layer of the graft. Radially enlargeable grafts of the present invention may be combined with various types of stents or anchoring systems, to form endovascular graft devices which are transluminally insertable and implantable within the lumen of a host blood vessel. Alternatively, radially enlargeable grafts of the present invention may be implanted by way of traditional surgical graft implantation techniques, without any radial enlargement of the graft at the time of implantation, so as to take advantage of the improved strength properties and suture-holding properties of the radially-shrunken tape-reinforced grafts of the present invention.
    • 由烧结的含氟聚合物形成的带状增强的管状血管移植物,例如膨胀的烧结PTFE。 移植物包括基底移植物和施加于其上的加强带。 胶带可以螺旋地缠绕在移植物周围或螺旋地缠绕在围绕圆柱形心轴的管中,然后施加到移植物的外部。 组合的基底移植物和带或增强带管的径向收缩使血管移植物随后径向放大超过5%,而不会撕裂或破坏移植物的加强带层。 本发明的可径向扩大的移植物可以与各种类型的支架或锚定系统组合,以形成血管内移植装置,其可平移插入并且可植入主体血管的腔内。 或者,本发明的径向可放大的移植物可以通过传统的手术移植物植入技术植入,而在植入时没有移植物的任何径向扩大,以便利用改进的强度性质和缝线保持性能 本发明的径向缩小的带状增强移植物。
    • 3. 发明授权
    • Radially-expandable PTFE tape-reinforced vascular grafts
    • 径向可膨胀PTFE带增强血管移植物
    • US08062354B2
    • 2011-11-22
    • US11009196
    • 2004-12-10
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • A61F2/06
    • B29D23/001A61F2/06B65B57/14B65G47/31Y10T428/1328Y10T428/1352
    • A tape-reinforced tubular vascular graft formed of sintered fluoropolymer(s), such as expanded, sintered PTFE. The graft includes a base graft and a reinforcing tape applied thereto. The tape may be spirally wrapped about the graft or spirally wrapped into a tube about a cylindrical mandrel and then applied to the exterior of the graft. Radial shrinkage of the combined base graft and tape, or of the reinforcing tape tube, renders the vascular graft subsequently radially enlargeable by more than 5%, without tearing or breaking of the reinforcement tape layer of the graft. Radially enlargeable grafts of the present invention may be combined with various types of stents or anchoring systems, to form endovascular graft devices which are transluminally insertable and implantable within the lumen of a host blood vessel. Alternatively, radially enlargeable grafts of the present invention may be implanted by way of traditional surgical graft implantation techniques, without any radial enlargement of the graft at the time of implantation, so as to take advantage of the improved strength properties and suture-holding properties of the radially-shrunken tape-reinforced grafts of the present invention.
    • 由烧结的含氟聚合物形成的带状增强的管状血管移植物,例如膨胀的烧结PTFE。 移植物包括基底移植物和施加于其上的加强带。 胶带可以围绕移植物螺旋地包裹或螺旋地缠绕在围绕圆柱形心轴的管中,然后施加到移植物的外部。 组合的基底移植物和带或增强带管的径向收缩使血管移植物随后径向放大超过5%,而不会撕裂或破坏移植物的加强带层。 本发明的可径向扩大的移植物可以与各种类型的支架或锚定系统组合,以形成血管内移植装置,其可平移插入并且可植入主体血管的腔内。 或者,本发明的径向可放大的移植物可以通过传统的手术移植物植入技术植入,而在植入时没有移植物的任何径向扩大,以便利用改进的强度性质和缝线保持性能 本发明的径向缩小的带状增强移植物。
    • 4. 发明申请
    • Radially-expandable PTFE tape-reinforced vascular grafts
    • 径向可膨胀PTFE带增强血管移植物
    • US20050096737A1
    • 2005-05-05
    • US11009196
    • 2004-12-10
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • A61F2/06B29D23/00B65B57/14B65G47/31
    • B29D23/001A61F2/06B65B57/14B65G47/31Y10T428/1328Y10T428/1352
    • A tape-reinforced tubular vascular graft formed of sintered fluoropolymer(s), such as expanded, sintered PTFE. The graft includes a base graft and a reinforcing tape applied thereto. The tape may be spirally wrapped about the graft or spirally wrapped into a tube about a cylindrical mandrel and then applied to the exterior of the graft. Radial shrinkage of the combined base graft and tape, or of the reinforcing tape tube, renders the vascular graft subsequently radially enlargeable by more than 5%, without tearing or breaking of the reinforcement tape layer of the graft. Radially enlargeable grafts of the present invention may be combined with various types of stents or anchoring systems, to form endovascular graft devices which are transluminally insertable and implantable within the lumen of a host blood vessel. Alternatively, radially enlargeable grafts of the present invention may be implanted by way of traditional surgical graft implantation techniques, without any radial enlargement of the graft at the time of implantation, so as to take advantage of the improved strength properties and suture-holding properties of the radially-shrunken tape-reinforced grafts of the present invention.
    • 由烧结的含氟聚合物形成的带状增强的管状血管移植物,例如膨胀的烧结PTFE。 移植物包括基底移植物和施加于其上的加强带。 胶带可以围绕移植物螺旋地包裹或螺旋地缠绕在围绕圆柱形心轴的管中,然后施加到移植物的外部。 组合的基底移植物和带或增强带管的径向收缩使血管移植物随后径向放大超过5%,而不会撕裂或破坏移植物的加强带层。 本发明的可径向扩大的移植物可以与各种类型的支架或锚定系统组合,以形成血管内移植装置,其可平移插入并且可植入主体血管的腔内。 或者,本发明的径向可放大的移植物可以通过传统的手术移植物植入技术植入,而在植入时没有移植物的任何径向扩大,以便利用改进的强度性质和缝线保持性能 本发明的径向缩小的带状增强移植物。
    • 5. 发明授权
    • Process of manufacturing a radially expandable PTFE tape-reinforced vascular graft
    • 制造可扩张的PTFE带增强血管移植物的方法
    • US06267834B1
    • 2001-07-31
    • US09201953
    • 1998-12-01
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • B32B3126
    • B29D23/001A61F2/06Y10S623/901
    • A method for improving the radial enlargeability and other properties of tape-reinforced tubular vascular graft formed of sintered fluoropolymer(s), such as expanded, sintered PTFE. Broadly, the method comprises the step of radially shrinking the reinforcement tape layer of the graft, or the entire tape-reinforced graft, after sintering thereof. Such radial shrinkage of the reinforcement tape layer, or of the entire graft, renders the graft subsequently radially enlargeable by more than 5%, without tearing or breaking of the reinforcement tape layer of the graft. Radially enlargeable grafts of the present invention may be combined with various types of stents or anchoring systems, to form endovascular graft devices which are transluminally insertable and implantable within the lumen of a host blood vessel. Alternatively, radially enlargeable grafts of the present invention may be implanted by way of traditional surgical graft implantation techniques, without any radial enlargement of the graft at the time of implantation, so as to take advantage of the improved strength properties and suture-holding properties of the radially-shrunken tape-reinforced grafts of the present invention.
    • 一种用于改善由烧结的氟聚合物形成的带状增强的管状血管移植物的径向扩大性等的方法,例如膨胀的烧结PTFE。 广泛地,该方法包括在烧结之后径向收缩移植物的加强带层或整个带增强移植物的步骤。 增强带层或整个移植物的这种径向收缩使得移植物随后可以径向放大超过5%,而不会撕裂或破坏移植物的加强带层。 本发明的可径向扩大的移植物可以与各种类型的支架或锚定系统组合,以形成血管内移植装置,其可平移插入并且可植入主体血管的腔内。 或者,本发明的径向可放大的移植物可以通过传统的手术移植物植入技术植入,而在植入时没有移植物的任何径向扩大,以便利用改进的强度性质和缝线保持性能 本发明的径向缩小的带状增强移植物。
    • 6. 发明授权
    • Radially-enlargeable PTFE tape-reinforced vascular grafts and their
methods of manufacture
    • 可径向扩张的PTFE带增强血管移植物及其制造方法
    • US5843173A
    • 1998-12-01
    • US844482
    • 1997-04-18
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • A61F2/06B29D23/00
    • B29D23/001A61F2/06Y10S623/901
    • A method for improving the radial enlargeability and other properties of tape-reinforced tubular vascular graft formed of sintered fluoropolymer(s), such as expanded, sintered PTFE. Broadly, the method comprises the step of radially shrinking the reinforcement tape layer of the graft, or the entire tape-reinforced graft, after sintering thereof. Such radial shrinkage of the reinforcement tape layer, or of the entire graft, renders the graft subsequently radially enlargeable by more than 5%, without tearing or breaking of the reinforcement tape layer of the graft. Radially enlargeable grafts of the present invention may be combined with various types of stents or anchoring systems, to form endovascular graft devices which are transluminally insertable and implantable within the lumen of a host blood vessel. Alternatively, radially enlargeable grafts of the present invention may be implanted by way of traditional surgical graft implantation techniques, without any radial enlargement of the graft at the time of implantation, so as to take advantage of the improved strength properties and suture-holding properties of the radially-shrunken tape-reinforced grafts of the present invention.
    • 一种用于改善由烧结的氟聚合物形成的带状增强的管状血管移植物的径向扩大性等的方法,例如膨胀的烧结PTFE。 广泛地,该方法包括在烧结之后径向收缩移植物的加强带层或整个带增强移植物的步骤。 增强带层或整个移植物的这种径向收缩使得移植物随后可以径向放大超过5%,而不会撕裂或破坏移植物的加强带层。 本发明的可径向扩大的移植物可以与各种类型的支架或锚定系统组合,以形成血管内移植装置,其可平移插入并且可植入主体血管的腔内。 或者,本发明的径向可放大的移植物可以通过传统的手术移植物植入技术植入,而在植入时没有移植物的任何径向扩大,以便利用改进的强度性质和缝线保持性能 本发明的径向缩小的带状增强移植物。
    • 7. 发明授权
    • Methods of manufacture of multiaxially oriented fluoropolymer films
    • 多轴取向氟聚合物膜的制造方法
    • US6099791A
    • 2000-08-08
    • US612742
    • 1996-03-08
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • B29C55/04B29C55/10B29C55/18B29C55/14
    • B29C55/045B29C55/10B29C55/18B29K2027/18
    • Porous fluoropolymer films, such as PTFE films, formed by a method including the steps of (a) forming a fluoropolymer (e.g., PTFE) paste, (b) extruding, calendaring, or otherwise processing the paste to form a film extrudate, (c) causing the film extrudate to be calendared in a first directional axis, (d) subsequently calendaring the film extrudate in a second directional axis which is different from the first directional axis, (e) subsequently calendaring the film extrudate in at least one additional directional axis which is different from said first and second directional axes, thereby forming a multiaxially calendared film extrudate, (f) drying the multiaxially calendared film extrudate, and (g) radially expanding the multiaxially calendared film extrudate to form a radially oriented fluoropolymer (e.g., PTFE) film. The porous fluoropolymer films formed by this method are multiaxially oriented and exhibit isotropic strength properties.
    • (a)形成含氟聚合物(例如,PTFE)糊剂的方法形成PTFE多孔膜等多孔含氟聚合物膜,(b)挤压,压延或以其他方式加工糊料以形成膜挤出物,(c )使得所述膜挤出物在第一方向轴上压延,(d)随后在不同于所述第一方向轴的第二方向轴上压延所述膜挤出物,(e)随后在至少一个另外的方向上压延所述膜挤出物 轴向不同于所述第一和第二方向轴,由此形成多轴压延膜挤出物,(f)干燥所述多轴压延膜挤出物,和(g)使所述多轴压延膜挤出物径向膨胀以形成径向取向的含氟聚合物(例如, PTFE)膜。 通过该方法形成的多孔含氟聚合物膜是多轴取向的并且具有各向同性的强度特性。
    • 8. 发明授权
    • Method of manufacturing a radially-enlargeable PTFE tape-reinforced
vascular graft
    • 制造可径向扩张的PTFE带增强血管移植物的方法
    • US5641373A
    • 1997-06-24
    • US423762
    • 1995-04-17
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • Donald ShannonJohn McIntyreChris KuoChris McCollamRobert Peterson
    • A61F2/06B29D23/00B29C61/04
    • B29D23/001A61F2/06Y10S623/901
    • A method for improving the radial enlargeability and other properties of tape-reinforced tubular vascular graft formed of sintered fluoropolymer(s), such as expanded, sintered PTFE. Broadly, the method comprises the step of radially shrinking the reinforcement tape layer of the graft, or the entire tape-reinforced graft, after sintering thereof. Such radial shrinkage of the reinforcement tape layer, or of the entire graft, renders the graft subsequently radially enlargeable by more than 5%, without tearing or breaking of the reinforcement tape layer of the graft. Radially enlargeable grafts of the present invention may be combined with various types of stents or anchoring systems, to form endovascular graft devices which are transluminally insertable and implantable within the lumen of a host blood vessel. Alternatively, radially enlargeable grafts of the present invention may be implanted by way of traditional surgical graft implantation techniques, without any radial enlargement of the graft at the time of implantation, so as to take advantage of the improved strength properties and suture-holding properties of the radially-shrunken tape-reinforced grafts of the present invention.
    • 一种用于改善由烧结的氟聚合物形成的带状增强的管状血管移植物的径向扩大性等的方法,例如膨胀的烧结PTFE。 广泛地,该方法包括在烧结之后径向收缩移植物的加强带层或整个带增强移植物的步骤。 增强带层或整个移植物的这种径向收缩使得移植物随后可以径向放大超过5%,而不会撕裂或破坏移植物的加强带层。 本发明的可径向扩大的移植物可以与各种类型的支架或锚定系统组合,以形成血管内移植装置,其可平移插入并且可植入主体血管的腔内。 或者,本发明的径向可放大的移植物可以通过传统的手术移植物植入技术植入,而在植入时没有移植物的任何径向扩大,以便利用改进的强度性质和缝线保持性能 本发明的径向缩小的带状增强移植物。