专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US4638639A Gas refrigeration method and apparatus 失效
标题翻译：气体制冷方法及装置
公开(公告)号：US4638639A
公开(公告)日：1987-01-27
申请号：US758001
申请日：1985-07-23
申请人： John Marshall , John D. Oakey
发明人： John Marshall , John D. Oakey
IPC分类号： F25J1/00 , F25B9/10 , F25J1/02
CPC分类号： F25J1/004 , F25J1/0015 , F25J1/0022 , F25J1/0037 , F25J1/0045 , F25J1/0072 , F25J1/0208 , F25J2270/06 , F25J2270/90 , F25J2290/10
摘要： A method of liquefying a permanent gas stream, includes the steps of reducing the temperature of the permanent gas stream at elevated pressure to below its critical pressure and performing at least two working fluid cycles to provide at least part of the refrigeration necessary to reduce the temperature of the permanent gas to below its critical temperature. Each working fluid cycle comprises work-expanding the cooled working fluid in countercurrent heat exchange with the permanent gas stream and with the working fluid being cooled, refrigeration thereby being provided for the permanent gas stream. In at least one working fluid cycle, work-expanded working fluid is brought into countercurrent heat exchange relationship with the permanent gas stream at a temperature below the critical temperature of the permanent gas and in the or each such cycle on completion of the work expansion the working fluid is at a pressure of at least 10 atmospheres.
摘要翻译：一种液化永久性气体流的方法包括以下步骤：将永久气体流在升高的压力下降低至其临界压力以下，并执行至少两个工作流体循环以提供必要的至少一部分制冷以降低温度的永久气体低于其临界温度。每个工作流体循环包括使冷却的工作流体与永久气流逆流热交换并且工作流体被冷却的工作膨胀，由此为永久气流提供制冷。在至少一个工作流体循环中，工作膨胀的工作流体在低于永久气体的临界温度的温度下与永久性气体流形成逆流热交换关系，并且在工作膨胀完成时或每个这样的循环中工作流体处于至少10个大气压的压力。

2. 发明授权

US4638638A Refrigeration method and apparatus 失效
标题翻译：制冷方法及装置
公开(公告)号：US4638638A
公开(公告)日：1987-01-27
申请号：US758000
申请日：1985-07-23
申请人： John Marshall , John D. Oakey
发明人： John Marshall , John D. Oakey
IPC分类号： F25J1/00 , F25B9/10 , F25J1/02
CPC分类号： F25J1/0208 , F25J1/0015 , F25J1/0022 , F25J1/004 , F25J1/0045 , F25J2270/06 , F25J2270/90
摘要： A method of liquefying a permanent gas stream includes the step of reducing the temperature of the permanent gas stream at elevated pressure to below its critical temperature. The reduction in temperature is effected at least in part by countercurrent heat exchange with work expanded working fluid, at least some of which is at a temperature below the critical temperature of the permanent gas when it is brought into heat exchange relationship with the permanent gas stream. The permanent gas stream after being cooled to below its critical temperature is then subjected to at least three successive isenthalpic expansions. Resulting flash gas is separated from the resulting liquid. At least some of the flash gas is heat exchanged with the permanent gas stream at elevated pressure.
摘要翻译：液化永久性气流的方法包括将升高的压力下的永久气体流的温度降低到其临界温度以下的步骤。至少部分地通过与工作膨胀的工作流体进行逆流热交换来实现温度的降低，当工作膨胀的工作流体与永久气流成热交换关系时，其至少一些温度低于永久气体的临界温度。然后将冷却至其临界温度之后的永久气流经历至少三次连续的等焓膨胀。产生的闪蒸气体与所得液体分离。至少一些闪蒸气体在升高的压力下与永久气流热交换。

3. 发明申请

US20190008294A1 Adjustable Pillow 审中-公开
公开(公告)号：US20190008294A1
公开(公告)日：2019-01-10
申请号：US15642099
申请日：2017-07-05
申请人： John Marshall
发明人： John Marshall
IPC分类号： A47G9/10
摘要： An adjustable pillow comprises an outer wall, an interior cavity having a volume defined by the outer wall, a composition of fill material dispersed about and contained within the interior cavity, and a drawstring for adjusting and fixing the volume of the interior cavity. The drawstring is defined by a base end, a distal end, an interior portion, and an exterior portion. It further comprises a cinching mechanism adjustably affixed to its exterior portion. A user can manipulate the volume of the interior cavity of the adjustable pillow, and, thus, the firmness of the adjustable pillow, by altering the position of the cinching mechanism along the drawstring. The drawstring further comprises a plurality of notations that provide the user with an indication of the firmness of the adjustable pillow at various positions of the cinching mechanism along the drawstring.

4. 发明授权

US09403876B2 Cyclic-GluR6 analogs, methods of treatment and use 有权
标题翻译： Cyclic-GluR6类似物，治疗和使用方法
公开(公告)号：US09403876B2
公开(公告)日：2016-08-02
申请号：US13320848
申请日：2010-05-18
申请人： Mark Spaller , John Marshall , Dennis J. Goebel
发明人： Mark Spaller , John Marshall , Dennis J. Goebel
IPC分类号： A61K38/12 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , C07K7/56 , A61K38/00
CPC分类号： A61K38/12 , A61K9/0019 , A61K9/0034 , A61K9/006 , A61K9/0085 , A61K31/135 , A61K31/198 , A61K31/395 , A61K31/401 , A61K31/42 , A61K38/00 , A61K45/06 , C07K7/56 , Y10T428/2982 , A61K2300/00
摘要： A composition which is reversible inhibitor of at least one neuron-specific PDZ domain comprising wherein R is a molecular transporter with or without a linker amino acid; R1 is at least about one amino acid covalently bound; and, R2 is isoleucine, leucine, alanine, phenylalanine, or valine, and methods of use.
摘要翻译：一种组合物，其是至少一种神经元特异性PDZ结构域的可逆抑制剂，其包含其中R是具有或不具有连接体氨基酸的分子转运体; R1是共价结合的至少约一个氨基酸; 和R2是异亮氨酸，亮氨酸，丙氨酸，苯丙氨酸或缬氨酸，以及使用方法。

5. 发明申请

US20130212278A1 CONTROLLING DISTRIBUTION OF RESOURCES IN A NETWORK 有权
标题翻译：控制资源在网络中的分配
公开(公告)号：US20130212278A1
公开(公告)日：2013-08-15
申请号：US13396356
申请日：2012-02-14
申请人： John Marshall , Adam Rykowski , Erich Stuntebeck , Jyothiprakash Halebeed
发明人： John Marshall , Adam Rykowski , Erich Stuntebeck , Jyothiprakash Halebeed
IPC分类号： G06F15/16
CPC分类号： H04L47/70 , G06F21/31 , G06F21/6218 , H04L63/102
摘要： Disclosed are various embodiments for controlling distribution of data on a network. In one embodiment, a distribution service receives a request from a user on a client device to access the distribution service. In response, the distribution service determines whether the user and the client device are authorized to access the distribution service. The distribution service identifies which of the resources are accessible to the user and the client device pairing based on a plurality of resource grouping identifiers. The distribution service then determines whether the client device complies with a plurality of distribution rules associated with the identified resources. Upon determining that the client device is compliant, the distribution service transmits the resources related to the compliance.
摘要翻译：公开了用于控制网络上的数据分发的各种实施例。在一个实施例中，分发服务在客户端设备上接收来自用户的访问分发服务的请求。作为响应，分发服务确定用户和客户端设备是否被授权访问分发服务。分发服务基于多个资源分组标识符识别用户可访问哪些资源和客户端设备配对。然后，分发服务确定客户端设备是否符合与所识别的资源相关联的多个分发规则。在确定客户端设备是否兼容时，分发服务传输与合规性相关的资源。

6. 发明申请

US20130190737A1 APPLICATION OF ENERGY IN MEDICAL TREATMENTS 审中-公开
标题翻译：能源在医疗治疗中的应用
公开(公告)号：US20130190737A1
公开(公告)日：2013-07-25
申请号：US13738675
申请日：2013-01-10
申请人： David Muller , John Marshall
发明人： David Muller , John Marshall
IPC分类号： A61F9/007
CPC分类号： A61F9/0079 , A61F9/00736 , A61F9/008 , A61F2009/0087 , A61F2009/00887 , A61N5/062 , A61N2005/0661
摘要： Embodiments apply light energy in medical treatments. To enhance or control the effect of the light energy, embodiments apply the light energy after tissue has been treated, e.g., with a photosensitizing agent. For example, embodiments may treat target tissue with riboflavin before exposure to ultraviolet light. For example, a system for cataract surgery includes a removal system configured to remove a first lens from an eye, wherein a capsular bag remains in the eye after removal of the first lens. The system includes an application system configured to treat lenticular epithelial cells in the capsular bag with the photosensitizing agent. The system includes a delivery system with a light source and an optical device. The optical device delivers light to the treated lenticular epithelial cells. Energy from the light destroys the lenticular epithelial cells in the capsular bag to reduce the growth of epithelial cells that cause posterior capsule opacification.
摘要翻译：实施例在光疗中应用光能。为了增强或控制光能的效果，实施例在组织被处理后例如用光敏剂施加光能。例如，实施方案可以在暴露于紫外线之前用核黄素治疗靶组织。例如，用于白内障手术的系统包括被配置为从眼睛去除第一透镜的去除系统，其中在移除第一透镜之后，囊袋保留在眼睛中。该系统包括被配置成用光敏剂治疗囊袋中的透镜上皮细胞的应用系统。该系统包括具有光源和光学装置的传送系统。光学器件将光递送到经处理的透镜上皮细胞。来自光的能量破坏囊袋中的透镜上皮细胞以减少导致后囊不透明的上皮细胞的生长。

7. 发明授权

US08366689B2 Method for making structural changes in corneal fibrils 失效
标题翻译：角膜原纤维结构变化的方法
公开(公告)号：US08366689B2
公开(公告)日：2013-02-05
申请号：US12570959
申请日：2009-09-30
申请人： John Marshall , Ali Hussein , David Muller
发明人： John Marshall , Ali Hussein , David Muller
IPC分类号： A61M35/00 , A61B18/18
CPC分类号： A61F9/008 , A61F9/0079 , A61F9/009 , A61F2009/00853 , A61F2009/00872
摘要： In a system for stabilizing a pattern of structural changes in corneal fibrils, an eye treatment system causes corneal fibrils of a cornea of an eye to transition from a first structure to a second structure. An application device applies a cross-linking element to the corneal fibrils. An activating device applies an initiating element to the corneal fibrils and activates the cross-linking element. The cross-linking element causes cross-linking in the corneal fibrils to preserve the second structure of the corneal fibrils. Another application device may apply a cross-linking breaker to the corneal fibrils. The cross-linking breaker halts or reverses at least partially the cross-linking in the corneal fibrils. Another activating device applies an initiating element to the corneal fibrils and activates the cross-linking breaker. Advantageously, the cross-linking breaker provides greater control over the amount and progress of cross-linking that occurs in the corneal fibrils.
摘要翻译：在用于稳定角膜原纤维结构变化的模式的系统中，眼睛治疗系统使眼睛角膜的角膜原纤维从第一结构转变到第二结构。应用装置将交联元件应用于角膜原纤维。激活装置将起始元件施加到角膜原纤维并激活交联元件。交联元件引起角膜原纤维中的交联以保留角膜原纤维的第二结构。另一应用装置可以将交联断路器应用于角膜原纤维。交联断路器至少部分地停止或逆转角膜原纤维中的交联。另一激活装置将起始元件施加到角膜原纤维并激活交联断路器。有利地，交联断路器对角膜原纤维中发生的交联的量和进展提供更大的控制。

8. 发明申请

US20120215155A1 CONTROLLED CROSS-LINKING INITIATION AND CORNEAL TOPOGRAPHY FEEDBACK SYSTEMS FOR DIRECTING CROSS-LINKING 审中-公开
标题翻译：控制交叉引导和导向交叉连接的角度反射系统
公开(公告)号：US20120215155A1
公开(公告)日：2012-08-23
申请号：US13438705
申请日：2012-04-03
申请人： David Muller , John Marshall , Marc D. Friedman , Stephen Blinn , Ronald Scharf , Pavel Kamaev , Radha Pertaub
发明人： David Muller , John Marshall , Marc D. Friedman , Stephen Blinn , Ronald Scharf , Pavel Kamaev , Radha Pertaub
IPC分类号： A61M37/00
CPC分类号： A61F9/008 , A61B3/102 , A61B3/107 , A61B2018/00619 , A61F9/0079 , A61F2009/00844 , A61F2009/00851 , A61F2009/00872 , A61F2009/00882 , A61N5/062 , A61N2005/0659 , A61N2005/0661
摘要： Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller. The feedback system may include an interferometer system, a corneal polarimetry system, or other configurations for monitoring cross-linking activity within the cornea. The controller is adapted to analyze the feedback information and adjust treatment to the eye based on the information. Aspects of the feedback system may also be used to monitor and diagnose features of the eye. Methods of activating cross-linking according to information provided by a feedback system in order to improve accuracy and safety of a cross-linking therapy are also provided.
摘要翻译：用于激活角膜组织内的交联以在眼睛治疗治疗之后稳定和加强角膜组织的装置和方法。提供反馈系统以获取测量并将反馈信息传递给控制器。反馈系统可以包括干涉仪系统，角膜偏振仪系统或用于监测角膜内的交联活动的其它构型。该控制器适用于分析反馈信息，并根据信息调整眼睛治疗。反馈系统的方面也可用于监测和诊断眼睛的特征。还提供了根据反馈系统提供的信息激活交联的方法，以提高交联疗法的准确性和安全性。

9. 发明申请

US20120149646A1 LONG TERM POTENTIATION WITH CYCLIC-GLUR6 ANALOGS 有权
标题翻译：长期稳定与周期性GLUR6模拟
公开(公告)号：US20120149646A1
公开(公告)日：2012-06-14
申请号：US13389047
申请日：2010-08-27
申请人： John Marshall , Andrew Mallon
发明人： John Marshall , Andrew Mallon
IPC分类号： A61K38/12 , A61P25/00 , A61P25/28
CPC分类号： A61K38/12 , A61K47/645
摘要： This invention discloses CN2097-like compositions that facilitate the induction of long-term potentiation (LTP). In one embodiment the method comprises inducing long-term potentiation in a subject by the method of administering a therapeutically effective dose of a CN2907-like compound.
摘要翻译：本发明公开了促进长期增强（LTP）诱导的CN2097样组合物。在一个实施方案中，该方法包括通过施用治疗有效剂量的CN2907样化合物的方法在受试者中诱导长期增强作用。

10. 外观设计

USD652719S1 Smile creases for a container 有权
公开(公告)号：USD652719S1
公开(公告)日：2012-01-24
申请号：US29364521
申请日：2010-06-24
申请人： Craig Caldwell , John Marshall , William Rasile
设计人： Craig Caldwell , John Marshall , William Rasile

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式