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    • 1. 发明申请
    • EYE THERAPY SYSTEM
    • 眼睛治疗系统
    • US20100094197A1
    • 2010-04-15
    • US12570959
    • 2009-09-30
    • John MarshallAli HusseinDavid Muller
    • John MarshallAli HusseinDavid Muller
    • A61F9/013
    • A61F9/008A61F9/0079A61F9/009A61F2009/00853A61F2009/00872
    • In a system for stabilizing a pattern of structural changes in corneal fibrils, an eye treatment system causes corneal fibrils of a cornea of an eye to transition from a first structure to a second structure. An application device applies a cross-linking element to the corneal fibrils. An activating device applies an initiating element to the corneal fibrils and activates the cross-linking element. The cross-linking element causes cross-linking in the corneal fibrils to preserve the second structure of the corneal fibrils. Another application device may apply a cross-linking breaker to the corneal fibrils. The cross-linking breaker halts or reverses at least partially the cross-linking in the corneal fibrils. Another activating device applies an initiating element to the corneal fibrils and activates the cross-linking breaker. Advantageously, the cross-linking breaker provides greater control over the amount and progress of cross-linking that occurs in the corneal fibrils.
    • 在用于稳定角膜原纤维结构变化的模式的系统中,眼睛治疗系统使眼睛角膜的角膜原纤维从第一结构转变到第二结构。 应用装置将交联元件应用于角膜原纤维。 激活装置将起始元件施加到角膜原纤维并激活交联元件。 交联元件引起角膜原纤维中的交联以保留角膜原纤维的第二结构。 另一应用装置可以将交联断路器应用于角膜原纤维。 交联断路器至少部分地停止或逆转角膜原纤维中的交联。 另一激活装置将起始元件施加到角膜原纤维并激活交联断路器。 有利地,交联断路器对角膜原纤维中发生的交联的量和进展提供更大的控制。
    • 2. 发明授权
    • Method for making structural changes in corneal fibrils
    • 角膜原纤维结构变化的方法
    • US08366689B2
    • 2013-02-05
    • US12570959
    • 2009-09-30
    • John MarshallAli HusseinDavid Muller
    • John MarshallAli HusseinDavid Muller
    • A61M35/00A61B18/18
    • A61F9/008A61F9/0079A61F9/009A61F2009/00853A61F2009/00872
    • In a system for stabilizing a pattern of structural changes in corneal fibrils, an eye treatment system causes corneal fibrils of a cornea of an eye to transition from a first structure to a second structure. An application device applies a cross-linking element to the corneal fibrils. An activating device applies an initiating element to the corneal fibrils and activates the cross-linking element. The cross-linking element causes cross-linking in the corneal fibrils to preserve the second structure of the corneal fibrils. Another application device may apply a cross-linking breaker to the corneal fibrils. The cross-linking breaker halts or reverses at least partially the cross-linking in the corneal fibrils. Another activating device applies an initiating element to the corneal fibrils and activates the cross-linking breaker. Advantageously, the cross-linking breaker provides greater control over the amount and progress of cross-linking that occurs in the corneal fibrils.
    • 在用于稳定角膜原纤维结构变化的模式的系统中,眼睛治疗系统使眼睛角膜的角膜原纤维从第一结构转变到第二结构。 应用装置将交联元件应用于角膜原纤维。 激活装置将起始元件施加到角膜原纤维并激活交联元件。 交联元件引起角膜原纤维中的交联以保留角膜原纤维的第二结构。 另一应用装置可以将交联断路器应用于角膜原纤维。 交联断路器至少部分地停止或逆转角膜原纤维中的交联。 另一激活装置将起始元件施加到角膜原纤维并激活交联断路器。 有利地,交联断路器对角膜原纤维中发生的交联的量和进展提供更大的控制。