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    • 4. 发明授权
      US5468747A Fungicidal compositions and methods of use employing pyrimidine derivatives 失效
    • Fungicidal compositions and methods of use employing pyrimidine derivatives
    • 杀真菌组合物和使用嘧啶衍生物的使用方法
    • US5468747A
    • 1995-11-21
    • US352858
    • 1994-12-02
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting , Rex Cheetham
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting , Rex Cheetham
    • A01N43/54 , C07D239/52 , C07D401/12 , A61K31/535 , A01N59/02 , A01N59/20
    • C07D401/12 , A01N43/54 , C07D239/52
    • Compounds having the formula (I): ##STR1## in which any two of K, L and M are nitrogen and the other is CE; X and Y are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.3-6 cycloalkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, C.sub.2-4 alkynyloxy, phenyl, benzyloxy, cyano, isocyano, isothiocyanato, nitro, NR.sup.1 R.sup.2, NR.sup.1 OR.sup.2,N.sub.3, NHCOR.sup.1, NR.sup.1 CO.sub.2 R.sup.2, NHCONR.sup.1 R.sup.2, N.dbd.CHNR.sup.1 R.sup.2, NHSO.sub.2 R.sup.1, OR.sup.1, OCOR.sup.1, OSO.sub.2 R.sup.1, SR.sup.1, SOR.sup.1, SO.sub.2 R.sup.1, SO.sub.2 OR.sup.1, SO.sub.2 NR.sup.1 R.sup.2, COR.sup.1, CR.sup.1 .dbd.NOR.sup.2, CHR.sup.1 CO.sub.2 R.sup.2, CO.sub.2 R.sup.1, CONR.sup.1 R.sup.2, CSNR.sup.1 R.sup.2, CH.sub.3 O.sub.2 C.C:CH.OCH.sub.3, 1-(imidazol-1-yl)vinyl, a 5-membered heterocyclic ring containing one, two or three nitrogen heteroatoms, or a 5- or 6-membered heterocyclic ring containing one or two oxygen or sulphur hetero-atoms, optionally a nitrogen heteroatom and optionally one or two oxo or thioxo substituents; or X and Y, when ortho to one another, join to form a 5- or 6-membered aliphatic or aromatic ring optionally containing one or two oxygen, sulphur or nitrogen atoms or one, two or three nitrogen atoms; A, B, D, E, G, U and V are independently hydrogen, halogen, C.sub.1-4 alkyl C.sub.1-4 alkoxy, cyano, nitro or trifluoromethyl; and R.sup.1 and R.sup.2 are independently hydrogen, C.sub.1-4 alkyl, C.sub.2-4 alkenyl or phenyl; the aliphatic moieties of any of theforegoing being optionally substituted with one or more of halogen, cyano, OR.sup.1, SR.sup.1, NR.sup.1 R.sup.2, SiR.sup.1.sub.3 or OCOR.sup.1 and the phenyl moieties of any of the foregoing being optionally substituted with one or more of halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro or cyano. The compounds are useful as fungicides.
    • 具有式（I）的化合物：其中K，L和M中的任一个为氮，另一个为CE; X和Y独立地是氢，卤素，C 1-4烷基，C 3-6环烷基，C 2-4烯基，C 2-4炔基，C 2-4炔氧基，苯基，苄氧基，氰基，异氰基，异硫氰酸酯基，硝基，NR1R2，NR1OR2， N3，NHCOR1，NR1CO2R2，NHCONR1R2，N = CHNR1R2，NHSO2R1，OR1，OCOR1，OSO2R1，SR1，SOR1，SO2R1，SO2OR1，SO2NR1R2，COR1，CR1 = NOR2，CHR1CO2R2，CO2R1，CONR1R2，CSNR1R2，CH3O2C.C：CH。 OCH 3，1-（咪唑-1-基）乙烯基，含有一个，两个或三个氮杂原子的5元杂环，或含有一个或两个氧或硫杂原子的5或6元杂环，任选地 氮杂原子和任选的一个或两个氧代或硫代取代基; 或X和Y，当彼此邻接时，连接形成任选地含有一个或两个氧，硫或氮原子或一个，两个或三个氮原子的5-或6-元脂族或芳族环; A，B，D，E，G，U和V独立地为氢，卤素，C 1-4烷基C 1-4烷氧基，氰基，硝基或三氟甲基; 并且R 1和R 2独立地是氢，C 1-4烷基，C 2-4链烯基或苯基; 任何前述的脂族部分任选被一个或多个卤素，氰基，OR 1，SR 1，NR 1 R 2，SiR 13或OCOR 1取代，任何前述的苯基部分任选被一个或多个卤素，C 1-4 烷基，C 1-4烷氧基，硝基或氰基。 这些化合物可用作杀真菌剂。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 7. 发明授权
      US5059605A Pyrimidine derivatives useful as fungicides 失效
    • Pyrimidine derivatives useful as fungicides
    • 吡咯烷酮衍生物有效用作杀真菌剂
    • US5059605A
    • 1991-10-22
    • US506790
    • 1990-04-10
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting
    • A01N43/54 , C07D20060101 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14
    • C07D401/12 , A01N43/54
    • Fungicidal compounds having the formula (I): ##STR1## in which any two of K, L and M are nitrogen and the other is CE; X and Y are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.3-6 cycloalkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, C.sub.2-4 alkenyloxy, C.sub.2-4 alkynyloxy, phenyl, benzyloxy, cyano, isocyano, isothiocyanato, nitro, NR.sup.1 R.sup.2, NR.sup.1 OR.sup.2, N.sub.3, NHCOR.sup.1, NR.sup.1 CO.sub.2 R.sup.2, NHCONR.sup.1 R.sup.2, N.dbd.CHNR.sup.1 R.sup.2, NHSO.sub.2 R.sup.1, OR.sup.1, OCOR.sup.1, OSO.sub.2 R.sup.1, SR.sup.1, SOR.sup.1, SO.sub.2 R.sup.1, SO.sub.2 OR.sup.1, SO.sub.2 NR.sup.1 R.sup.2, COR.sup.1, CR.sup.1 .dbd.NOR.sup.2, CHR.sup.1 CO.sub.2 R.sup.2, CO.sub.2 R.sup.2, CO.sub.2 R.sup.1, CONR.sup.1 R.sup.2, CSNR.sup.1 R.sup.2, CH.sub.3 O.sub.2 C.C:CH.OCH.sub.3, 1-(imidazol-1-yl)vinyl, a 5-membered heterocyclic ring containing one, two or three nitrogen heteroatoms, or a 5- or 6-membered heterocyclic ring containing one or two oxygen or sulphur heteroatoms, optionally a nitrogen heteroatom and optionally one or two oxo or thioxo substituents; or X and Y, when ortho to one another, join to form a 5- or 6-membered aliphatic or aromatic ring optionally containing one or two oxygen, sulphur or nitrogen atoms or one, two or three nitrogen or sulphur atoms; A, B, E, G and U are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, cyano, nitro or trifluoromethyl; and R.sup.1 and R.sup.2 are independently hydrogen, C.sub.1-4 alkyl, C.sub.2-4 alkenyl or phenyl; the aliphatic moieties of any of the foregoing being optionally substituted with one or more of halogen, cyano, OR.sup.1, SR.sup.1, NR.sup.1 R.sup.2, SiR.sup.1.sub.3 or OCOR.sup.1 and the phenyl moieties of any of the foregoing being optionally substituted with one or more of halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro or cyano; and their pyridine N-oxides and N-alkyl pyridinium salts.
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 8. 发明授权
      US5264440A Fungicides 失效
    • Fungicides
    • 杀菌剂
    • US5264440A
    • 1993-11-23
    • US900267
    • 1992-07-20
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting , Rex Cheetham
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting , Rex Cheetham
    • A01N43/54 , C07D239/52 , C07D401/12 , C07D413/12 , C07D417/12
    • C07D401/12 , A01N43/54 , C07D239/52
    • Compounds having the formula (I): ##STR1## in which any two of K, L and M are nitrogen and the other is CE; X and Y are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.3-6 cycloalkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, C.sub.2-4 alkynyloxy, phenyl, benzyloxy, cyano, isocyano, isothiocyanato, nitro, NR.sup.1 R.sup.2, NR.sup.1 OR.sup.2,N.sub.3, NHCOR.sup.1, NR.sup.1 CO.sub.2 R.sup.2, NHCONR.sup.1 R.sup.2, N.dbd.CHNR.sup.1 R.sup.2, NHSO.sub.2 R.sup.1, OR.sup.1, OCOR.sup.1, OSO.sub.2 R.sup.1, SR.sup.1, SOR.sup.1, SO.sub.2 R.sup.1, SO.sub.2 OR.sup.1, SO.sub.2 NR.sup.1 R.sup.2, COR.sup.1, CR.sup.1 .dbd.NOR.sup.2, CHR.sup.1 CO.sub.2 R.sup.2, CO.sub.2 R.sup.1, CONR.sup.1 R.sup.2, CSNR.sup.1 R.sup.2, CH.sub.3 O.sub.2 C.C:CH.OCH.sub.3, 1-(imidazol-1-yl)vinyl, a 5-membered heterocyclic ring containing one, two or three nitrogen heteroatoms, or a 5- or 6-membered heterocyclic ring containing one or two oxygen or sulphur hetero-atoms, optionally a nitrogen heteroatom and optionally one or two oxo or thioxo substituents; or X and Y, when ortho to one another, join to form a 5- or 6-membered aliphatic or aromatic ring optionally containing one or two oxygen, sulphur or nitrogen atoms or one, two or three nitrogen atoms; A, B, D, E, G, U and V are independently hydrogen, halogen, C.sub.1-4 alkyl C.sub.1-4 alkoxy, cyano, nitro or trifluoromethyl; and R.sup.1 and R.sup.2 are independently hydrogen, C.sub.1-4 alkyl, C.sub.2-4 alkenyl or phenyl; the aliphatic moieties of any of the foregoing being optionally substituted with one or more of halogen, cyano, OR.sup.1, SR.sup.1, NR.sup.1 R.sup.2, SiR.sup.1.sub.3 or OCOR.sup.1 and the phenyl moieties of any of the foregoing being optionally substituted with one or more of halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro or cyano. The compounds are useful as fungicides.
    • 具有式（I）的化合物：其中K，L和M中的任一个为氮，另一个为CE; X和Y独立地是氢，卤素，C 1-4烷基，C 3-6环烷基，C 2-4烯基，C 2-4炔基，C 2-4炔氧基，苯基，苄氧基，氰基，异氰基，异硫氰酸酯基，硝基，NR1R2，NR1OR2， N3，NHCOR1，NR1CO2R2，NHCONR1R2，N = CHNR1R2，NHSO2R1，OR1，OCOR1，OSO2R1，SR1，SOR1，SO2R1，SO2OR1，SO2NR1R2，COR1，CR1 = NOR2，CHR1CO2R2，CO2R1，CONR1R2，CSNR1R2，CH3O2C.C：CH。 OCH 3，1-（咪唑-1-基）乙烯基，含有一个，两个或三个氮杂原子的5元杂环，或含有一个或两个氧或硫杂原子的5或6元杂环，任选地 氮杂原子和任选的一个或两个氧代或硫代取代基; 或X和Y，当彼此邻接时，连接形成任选地含有一个或两个氧，硫或氮原子或一个，两个或三个氮原子的5-或6-元脂族或芳族环; A，B，D，E，G，U和V独立地为氢，卤素，C 1-4烷基C 1-4烷氧基，氰基，硝基或三氟甲基; 并且R 1和R 2独立地是氢，C 1-4烷基，C 2-4链烯基或苯基; 前述任何一个的脂肪族部分任选被一个或多个卤素，氰基，OR 1，SR 1，NR 1 R 2，SiR 13或OCOR 1取代，并且前述任何一个的苯基部分任选被一个或多个卤素， C4烷基，C1-4烷氧基，硝基或氰基。 这些化合物可用作杀真菌剂。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 9. 发明授权
      US5145856A Fungicides 失效
    • Fungicides
    • 杀菌剂
    • US5145856A
    • 1992-09-08
    • US818431
    • 1991-12-27
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting , Rex Cheetham
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting , Rex Cheetham
    • A01N43/54 , C07D239/52 , C07D401/12
    • C07D401/12 , A01N43/54 , C07D239/52
    • Compounds having the formula (I): ##STR1## in which any two of K, L and M are nitrogen and the other is CE; X and Y are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.3-6 cycloalkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, C.sub.2-4 alkynyloxy, phenyl, benzyloxy, cyano, isocyano, isothiocyanato, nitro, NR.sup.1 R.sup.2, NR.sup.1 OR.sup.2, N.sub.3, NHCOR.sup.1, NR.sup.1 CO.sub.2 R.sup.2, NHCONR.sup.1 R.sup.2, N.dbd.CHNR.sup.1 R.sup.2, NHSO.sub.2 R.sup.1, OR.sup.1, OCOR.sup.1, OSO.sub.2 R.sup.1, SR.sup.1, SOR.sup.1, SO.sub.2 R.sup.1, SO.sub.2 OR.sup.1, SO.sub.2 NR.sup.1 R.sup.2, COR.sup.1, CR.sup.1 .dbd.NOR.sup.2, CHR.sup.1 CO.sub.2 R.sup.2, CO.sub.2 R.sup.1, CONR.sup.1 R.sup.2, CSNR.sup.1 R.sup.2, CH.sub.3 O.sub.2 C.C:CH.OCH.sub.3, 1-(imidazol-1-yl)vinyl, a 5-membered heterocyclic ring containing one, two or three nitrogen heteroatoms, or a 5- or 6-membered heterocyclic ring containing one or two oxygen or sulphur hetero-atoms, optionally a nitrogen heteroatom and optionally one or two oxo or thioxo substituents; or X and Y, when ortho to one another, join to form a 5- or 6-membered aliphatic or aromatic ring optionally containing one or two oxygen, sulphur or nitrogen atoms or one, two or three nitrogen atoms; A, B, D, E, G, U and V are independently hydrogen, halogen, C.sub.1-4 alkyl C.sub.1-4 alkoxy, cyano, nitro or trifluoromethyl; and R.sup.1 and R.sup.2 are independently hydrogen, C.sub.1-4 alkyl, C.sub.2-4 alkenyl or phenyl; the aliphatic moieties of any of the foregoing being optionally substituted with one or more of halogen, cyano, OR.sup.1, SR.sup.1, NR.sup.1 R.sup.2, SiR.sup.1.sub.3 or OCOR.sup.1 and the phenyl moieties of any of the foregoing being optionally substituted with one or more of halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro or cyano. The compounds are useful as fungicides.
    • 具有式（I）的化合物：其中K，L和M中的任一个为氮，另一个为CE; X和Y独立地是氢，卤素，C 1-4烷基，C 3-6环烷基，C 2-4烯基，C 2-4炔基，C 2-4炔氧基，苯基，苄氧基，氰基，异氰基，异硫氰酸酯基，硝基，NR1R2，NR1OR2， N3，NHCOR1，NR1CO2R2，NHCONR1R2，N = CHNR1R2，NHSO2R1，OR1，OCOR1，OSO2R1，SR1，SOR1，SO2R1，SO2OR1，SO2NR1R2，COR1，CR1 = NOR2，CHR1CO2R2，CO2R1，CONR1R2，CSNR1R2，CH3O2C.C：CH。 OCH 3，1-（咪唑-1-基）乙烯基，含有一个，两个或三个氮杂原子的5元杂环，或含有一个或两个氧或硫杂原子的5或6元杂环，任选地 氮杂原子和任选的一个或两个氧代或硫代取代基; 或X和Y，当彼此邻接时，连接形成任选地含有一个或两个氧，硫或氮原子或一个，两个或三个氮原子的5-或6-元脂族或芳族环; A，B，D，E，G，U和V独立地为氢，卤素，C 1-4烷基C 1-4烷氧基，氰基，硝基或三氟甲基; 并且R 1和R 2独立地是氢，C 1-4烷基，C 2-4链烯基或苯基; 前述任何一个的脂肪族部分任选被一个或多个卤素，氰基，OR 1，SR 1，NR 1 R 2，SiR 13或OCOR 1取代，并且前述任何一个的苯基部分任选被一个或多个卤素， C4烷基，C1-4烷氧基，硝基或氰基。 这些化合物可用作杀真菌剂。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 10. 发明授权
      US5229391A Pyrimidine derivatives and their use as fungicidal agents 失效
    • Pyrimidine derivatives and their use as fungicidal agents
    • 嘧啶衍生物及其作为杀真菌剂的用途
    • US5229391A
    • 1993-07-20
    • US739468
    • 1991-08-02
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting
    • John M. Clough , Christopher R. A. Godfrey , Ian T. Streeting
    • A01N43/54 , C07D401/12
    • C07D401/12 , A01N43/54
    • Fungicidal compounds having the formula (I): ##STR1## in which any two of K, L and M are nitrogen and the other is CE; X and Y are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.3-6 cycloalkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, C.sub.2-4 alkenyloxy, C.sub.2-4 alkynyloxy, phenyl, benzyloxy, cyano, isocyano, isothiocyanato, nitro, NR.sup.1 R.sup.2, NR.sup.1 OR.sup.2, N.sub.3, NHCOR.sup.1, NR.sup.1 CO.sub.2 R.sup.2, NHCONR.sup.1 R.sup.2, N.dbd.CHNR.sup.1 R.sup.2, NHSO.sub.2 R.sup.1, OR.sup.1, OCOR.sup.1, OSO.sub.2 R.sup.1, SR.sup.1, SOR.sup.1, SO.sub.2 R.sup.1, SO.sub.2 OR.sup.1, SO.sub.2 NR.sup.1 R.sup.2, COR.sup.1, CR.sup.1 .dbd.NOR.sup.2, CHR.sup.1 CO.sub.2 R.sup.2, CO.sub.2 R.sup.1, CONR.sup.1 R.sup.2, CSNR.sup.1 R.sup.2, CH.sub.3 O.sub.2 C.C:CH.OCH.sub.3, 1-(imidazol-1-yl)vinyl, a 5-membered heterocyclic ring containing one, two or three nitrogen heteroatoms, or a 5- or 6-membered heterocyclic ring containing one or two oxygen or sulphur heteroatoms, optionally a nitrogen heteroatom and optionally one or two oxo or thioxo substituents; or X and Y, when ortho to one another, join to form a 5- or 6-membered aliphatic or aromatic ring optionally containing one or two oxygen, sulphur or nitrogen atoms or one, two or three nitrogen or sulphur atoms; A, B, E, G and U are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, cyano, nitro or trifluoromethyl; and R.sup.1 and R.sup.2 are independently hydrogen, C.sub.1-4 alkyl, C.sub.2-4 alkenyl or phenyl; the aliphatic moieties of any of the foregoing being optionally substituted with one or more of halogen, cyano, OR.sup.1, SR.sup.1, NR.sup.1 R.sup.2, SiR.sup.1.sub.3 or OCOR.sup.1 and the phenyl moieties of any of the foregoing being optionally substituted with one or more of halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro or cyano; and their pyridine N-oxides and N-alkyl pyridinium salts.
    • 具有式（I）的杀真菌化合物：其中K，L和M中的任一个为氮，另一个为CE; X和Y独立地是氢，卤素，C 1-4烷基，C 3-6环烷基，C 2-4烯基，C 2-4炔基，C 2-4链烯氧基，C 2-4炔氧基，苯基，苄氧基，氰基，异氰基，异硫氰酸根合，硝基 ，NR1R2，NR1OR2，N3，NHCOR1，NR1CO2R2，NHCONR1R2，N = CHNR1R2，NHSO2R1，OR1，OCOR1，OSO2R1，SR1，SOR1，SO2R1，SO2OR1，SO2NR1R2，COR1，CR1 = NOR2，CHR1CO2R2，CO2R1，CONR1R2，CSNR1R2，CH3O2C C：CH.OCH 3，1-（咪唑-1-基）乙烯基，含有一个，两个或三个氮杂原子的5元杂环，或含有一个或两个氧或硫的5-或6-元杂环 杂原子，任选的氮杂原子和任选的一个或两个氧代或硫代取代基; 或X和Y，当彼此邻接时，连接形成任选地含有一个或两个氧，硫或氮原子或一个，两个或三个氮或硫原子的5-或6-元脂族或芳族环; A，B，E，G和U独立地为氢，卤素，C 1-4烷基，C 1-4烷氧基，氰基，硝基或三氟甲基; 并且R 1和R 2独立地是氢，C 1-4烷基，C 2-4链烯基或苯基; 前述任何一个的脂肪族部分任选被一个或多个卤素，氰基，OR 1，SR 1，NR 1 R 2，SiR 13或OCOR 1取代，并且前述任何一个的苯基部分任选被一个或多个卤素， 4烷基，C 1-4烷氧基，硝基或氰基; 和它们的吡啶N-氧化物和N-烷基吡啶鎓盐。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
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