会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 4. 发明授权
    • Optical system
    • 光学系统
    • US08203702B1
    • 2012-06-19
    • US12287861
    • 2008-10-14
    • David M. KaneKelly HillmanChristopher HornbergJohn HuntAndrew E. Paul
    • David M. KaneKelly HillmanChristopher HornbergJohn HuntAndrew E. Paul
    • G01B11/26G01C1/00
    • G01J3/02B33Y80/00G01J3/0202G01J3/0208G01J3/021G01J3/0256G01J3/0289G01S7/4804G01S7/4817G01S7/495G01S17/023G01S17/89G02B13/04G02B26/0833G02B26/105G02B27/0075G02B27/644
    • Method/system locate external articles using source, detector (PSD), entrance aperture, and magnifying/reducing afocal element—expanding FOR>90°, or refining precision. Between (1) source or detector and (2) aperture, at least one plural-axis-rotatable mirror addresses source/detector throughout FOR. ½- to 15-centimeter mirror enables ˜25 to ˜45 μradian beam divergence. Aperture, afocal element, and mirror(s) define source-detector path. Mirror(s) rotate in refractory- (or air/magnetic-) bearing mount; or mirror array. Auxiliary optics illuminate mirror back, monitoring return to measure (null-balance feedback) angle. To optimize imaging, auxiliary radiation propagates via splitters toward array (paralleling measurement paths), then focusing on imaging detector. Focal quality is developed as a PSF, optimized vs. angle; stored results later recover optima. Mirror drive uses magnet(s) on mirror(s). “Piston” motion yields in-phase wavefronts, so array dimensions set diffraction limit. Also: destructive reply; scaling optimizes acceleration vs. thickness; passive systems.
    • 方法/系统使用源,检测器(PSD),入口孔径和放大/缩小焦点元件扩展FOR> 90°或提高精度定位外部物品。 在(1)源或检测器和(2)孔之间,至少一个多轴可旋转镜在FOR处寻址源/检测器。 ½到15厘米的镜子可以使〜25〜〜45微米的光束发散。 孔径,无焦点元件和反射镜定义了源 - 检测器路径。 镜子在耐火材料(或空气/磁性)轴承座中旋转; 或镜像阵列。 辅助光学镜照射反光镜,监视返回测量(零平衡反馈)角度。 为了优化成像,辅助辐射通过分离器传播到阵列(平行的测量路径),然后聚焦成像检测器。 焦点质量发展为PSF,优化与角度; 存储结果稍后恢复最佳。 镜面驱动器在镜子上使用磁铁。 “活塞”运动产生同相波前,因此阵列尺寸设定衍射极限。 还有:破坏性回复 缩放优化加速度与厚度; 被动系统。
    • 7. 发明授权
    • Printing compositions
    • 印刷组合物
    • US4426227A
    • 1984-01-17
    • US306392
    • 1981-09-28
    • Robert A. KeelingJohn Hunt
    • Robert A. KeelingJohn Hunt
    • B44C1/16B41M1/12B41M1/34B41M5/025B44C1/17C09D11/00C09D11/02
    • B44C1/1725B41M1/34C09D11/03Y10S260/38
    • A printing medium comprises a thermoplastic resin and a rheology-controlling diluent, the medium having a melting point of between 40.degree. and 80.degree. C., and being non-tacky at room temperature. The diluent is preferably selected from liquid resins, high molecular weight esters, fatty alcohols and saturated fatty acids. The medium is used in a method of decorating an article comprising forming an image of the decoration in a flowable ink composition on a heated support, picking up the image from the support on a silicone transfer member at a lower temperature to form a flexible film on the transfer member in a semi-fluid condition, and applying the film to an article to be decorated within a period of time during which the composition remains semi-fluid whereby the composition solidifies immediately on contact with the surface of the article to form a non-tacky coating thereon.
    • 印刷介质包括热塑性树脂和流变控制稀释剂,该介质的熔点在40℃至80℃之间,并且在室温下是非粘性的。 稀释剂优选选自液体树脂,高分子量酯,脂肪醇和饱和脂肪酸。 该介质用于装饰物品的方法,包括在加热的支撑件上的可流动的油墨组合物中形成装饰图像,在较低温度下从硅树脂转印构件上的载体上拾取图像,以形成柔性膜 所述转移构件处于半流体状态,并且在所述组合物保持半流体的时间期间内将所述膜施加到待装饰物品上,由此组合物在与所述制品的表面接触时立即固化以形成非 - 在其上涂层。
    • 10. 发明申请
    • Protein/Solubility Folding Assessed By Structural Complementation
    • 蛋白质/溶解度折叠由结构互补评估
    • US20070178498A1
    • 2007-08-02
    • US11617191
    • 2006-12-28
    • Philip ThomasJohn HuntWilliam WigleyRhesa Stidham
    • Philip ThomasJohn HuntWilliam WigleyRhesa Stidham
    • C12Q1/68G01N33/53
    • G01N33/502C07K1/113
    • Many proteins, when produced recombinantly, suffer from improper processing, folding and lack normal solubility. Modified proteins, including those indicative of disease states, also can have such defects. The present invention is directed to methods of identifying proper and improper protein folding, aberrant processing and/or insolubility. The method relies on the use of two components: a specialized fusion protein and structural complementation. The fusion protein contains sequences from the protein of interest and one portion of a marker protein that, by itself, is not active. A host cell then provides the remainder of the marker protein that serves to “complement” the function of the fused marker protein such that their association restores activity, permitting detection.
    • 当重组产生时,许多蛋白质经受不当的加工,折叠和缺乏正常的溶解度。 修饰的蛋白质,包括指示疾病状态的蛋白质,也可能具有这样的缺陷。 本发明涉及鉴定正确和不适当的蛋白质折叠,异常加工和/或不溶性的方法。 该方法依赖于两个组成部分的使用:一种专门的融合蛋白和结构互补。 融合蛋白包含来自目的蛋白质的序列和一部分本身不具有活性的标记蛋白质。 宿主细胞然后提供标记蛋白的其余部分,其用于“补充”融合标记蛋白的功能,使得它们的缔合恢复活性,允许检测。