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1. 发明授权

US5627056A Method of synthesizing lipids and cosmetic composition comprising them 失效
标题翻译：合成脂质的方法和包含它们的化妆品组合物
公开(公告)号：US5627056A
公开(公告)日：1997-05-06
申请号：US386140
申请日：1995-02-09
申请人： John Casey , Peter S. Cheetham , Peter C. Harries , Della Hyliands , John T. Mitchell , Anthony V. Rawlings
发明人： John Casey , Peter S. Cheetham , Peter C. Harries , Della Hyliands , John T. Mitchell , Anthony V. Rawlings
IPC分类号： A61K8/00 , A61K8/14 , A61K8/30 , A61K8/31 , A61K8/42 , A61K8/46 , A61K8/49 , A61K8/68 , A61K8/89 , A61K8/891 , A61Q3/00 , A61Q3/02 , A61Q5/00 , A61Q7/00 , A61Q19/00 , C07C231/02 , C07C231/12 , C07C235/08 , C07C235/28 , C07H15/04 , C07H15/10 , C12P13/00 , C12R1/78 , C12P7/64 , C12N1/00 , C12N1/14
CPC分类号： C07H15/04 , A61K8/68 , A61Q19/00 , A61Q3/00 , A61Q5/00 , C07C231/02 , C07C235/08 , C07C235/28 , C07H15/10 , C12P13/001 , C12P13/02 , A61K2800/85 , A61Q19/007 , A61Q19/08 , Y10S435/93
摘要： An efficient method of producing phytosphingosine-containing ceramide one comprising: (a) obtaining a phytosphingosine base from tetraacetylphytosphingosine (TAPS) by a deacetylation reaction wherein the TAPS is produced by fermentation of cells of the F-60-10 mating type strain of Hansenula ciferrii using a fed-batch mode and a non-fermentable carbon source; and (b) coupling together the phytosphingosine base and a fatty acid/.omega.-hydroxy fatty acid component wherein the .omega.-hydroxy fatty acid component is prepared by a process which includes Kolbe synthesis.
摘要翻译：一种生产含有植物鞘氨醇的神经酰胺的有效方法，其特征在于：（a）通过脱乙酰化反应从四乙酰鞘氨醇（TAPS）获得植物鞘氨醇碱，其中TAPS是通过发酵F-60-10交配型汉逊酵母菌株使用补料分批模式和不可发酵碳源; 和（b）将植物鞘氨醇碱和脂肪酸/ω-羟基脂肪酸组分偶联在一起，其中ω-羟基脂肪酸组分通过包括Kolb + E，acu e + EE合成的方法制备。

2. 发明授权

US6162422A Method of reducing or preventing malodour 有权
标题翻译：降低或防止恶臭的方法
公开(公告)号：US6162422A
公开(公告)日：2000-12-19
申请号：US348607
申请日：1999-07-06
申请人： John Casey , Jayne Elizabeth Ellis , Della Hyliands , Alexander Gordon James , Gary Mycock , David Taylor
发明人： John Casey , Jayne Elizabeth Ellis , Della Hyliands , Alexander Gordon James , Gary Mycock , David Taylor
IPC分类号： A61K8/37 , A61K8/85 , A61Q15/00 , A61Q17/00 , A61K7/32 , A61K7/00
CPC分类号： A61Q17/005 , A61K8/375 , A61K8/85 , A61Q15/00
摘要： Cosmetic method for reducing or preventing malodour by topically applying to human skin an active agent capable of inactivating body malodour-causing microorganisms comprising corynebacteria, characterised in that the agent is capable of inactivating, of the corynebacteria, only those corynebacteria capable of catabolising fatty acids.
摘要翻译：用于通过向人体皮肤局部施用能够灭活包含棒杆菌的体内产生恶臭的微生物的活性剂的化妆方法，其特征在于所述试剂能够使所述棒杆菌只能够分解代谢脂肪酸的那些棒状杆菌失活。

3. 发明申请

US20110237660A1 ORAL COMPOSITION 有权
标题翻译：口腔组成
公开(公告)号：US20110237660A1
公开(公告)日：2011-09-29
申请号：US13132932
申请日：2009-12-03
申请人： John Casey , Gail Jenkins , Linda Wainwright
发明人： John Casey , Gail Jenkins , Linda Wainwright
IPC分类号： A61K31/352 , A61P29/00 , A61P17/00 , A61P17/10
CPC分类号： A61K36/45 , A61K31/352 , A61K36/48 , A61K45/06 , A61K2300/00
摘要： A composition which is adapted for oral consumption comprising daidzein and an anthocyanidin, wherein the weight ratio of daidzein to anthocyanidin is in the range of from 1:1 to 1:100, wherein the daidzein is in the form of a pre-prepared aqueous dispersion, and wherein the composition is free of soy protein, which can exhibit an anti-inflammatory effect in skin, the use of a composition containing daidzein and an anthocyanidin for obtaining an anti-inflammatory effect in the skin and a method of reducing skin inflammation through the oral consumption of the composition.
摘要翻译：适合于口服消耗的组合物，其包含黄豆苷原和花青素，其中黄豆苷原与花色素的重量比在1:1至1:100的范围内，其中黄豆苷原为预制的水分散体，并且其中所述组合物不含大豆蛋白，其可以在皮肤中表现出抗炎作用，使用含有黄豆苷原和花色素的组合物以获得皮肤中的抗炎作用，以及通过以下方法减少皮肤炎症口服消耗的组合物。

4. 发明申请

US20080200546A1 Oral Composition For Enhancing Skin Properties 审中-公开
标题翻译：用于增强皮肤性质的口服组合物
公开(公告)号：US20080200546A1
公开(公告)日：2008-08-21
申请号：US11791783
申请日：2005-10-28
申请人： John Casey , Gail Jenkins , Julia Sarah Rogers , Simon David Wantling
发明人： John Casey , Gail Jenkins , Julia Sarah Rogers , Simon David Wantling
IPC分类号： A61K8/36 , A61Q19/00
CPC分类号： A23L33/155 , A23L33/105 , A23L33/115 , A23L33/15 , A23V2002/00 , A23V2250/1868 , A23V2250/187 , A23V2250/708 , A23V2250/712 , A23V2250/1842 , A23V2250/213 , A23V2250/211 , A23V2250/2116
摘要： A stable consumable emulsion, comprising at least 50% water, 0.2 to 3 wt % of an oil comprising at least 12 wt % of docosahexaenoic acid and eicosapentaenoic acid, an antioxidant, a flavouring and at least 0.01 wt % food-grade phospholipid emulsifier is provided which provides noticeable improvements in skin when consumed regularly.
摘要翻译：稳定的消耗性乳液，包含至少50％的水，0.2至3重量％的包含至少12重量％的二十二碳六烯酸和二十碳五烯酸的油，抗氧化剂，调味剂和至少0.01重量％的食品级磷脂乳化剂提供了定期消费时皮肤的显着改善。

5. 发明申请

US20050195052A1 Methods and apparatus for printing conductive thickfilms over thickfilm dielectrics 失效
标题翻译：在厚膜电介质上印刷导电厚膜的方法和装置
公开(公告)号：US20050195052A1
公开(公告)日：2005-09-08
申请号：US10793022
申请日：2004-03-03
申请人： Lewis Dove , John Casey
发明人： Lewis Dove , John Casey
IPC分类号： H01L21/48 , H01L21/768 , H01L49/00 , H01P3/08 , H05K1/02 , H05K1/09 , H05K3/00 , H05K3/46
CPC分类号： H01P3/088 , H01L21/4857 , H01L21/4867 , H05K1/0221 , H05K1/092 , H05K3/4667 , H05K2201/09154 , H05K2201/09981 , Y10T29/49155 , Y10T29/49156
摘要： In one embodiment, a plurality of thickfilm dielectric layers are printed on a substrate, with each successive layer being printed over a previous layer, and with each layer having sloped walls. After printing a first subset of the plurality of thickfilm dielectric layers, a first conductive thickfilm is printed over at least the walls of the first subset of dielectric layers. Then, after printing a second subset of the plurality of thickfilm dielectric layers, a second conductive thickfilm is printed over the second subset of dielectric layers (with the first and second conductive thickfilms being electrically coupled).
摘要翻译：在一个实施例中，多个厚膜电介质层印刷在衬底上，其中每个连续层被印刷在先前的层上，并且每个层具有倾斜的壁。在打印多个厚膜电介质层的第一子集之后，在至少第一电介质层子集的壁上印刷第一导电厚膜。然后，在印刷多个厚膜电介质层的第二子集之后，将第二导电厚膜印刷在电介质层的第二子集上（第一和第二导电厚膜电耦合）。

6. 发明授权

US08546445B2 Oral composition 有权
标题翻译：口语构成
公开(公告)号：US08546445B2
公开(公告)日：2013-10-01
申请号：US13132932
申请日：2009-12-03
申请人： John Casey , Gail Jenkins , Linda Jane Wainwright
发明人： John Casey , Gail Jenkins , Linda Jane Wainwright
IPC分类号： A61K31/352
CPC分类号： A61K36/45 , A61K31/352 , A61K36/48 , A61K45/06 , A61K2300/00
摘要： A composition which is adapted for oral consumption comprising daidzein and an anthocyanidin, wherein the weight ratio of daidzein to anthocyanidin is in the range of from 1:1 to 1:100, wherein the daidzein is in the form of a pre-prepared aqueous dispersion, and wherein the composition is free of soy protein, which can exhibit an anti-inflammatory effect in skin, the use of a composition containing daidzein and an anthocyanidin for obtaining an anti-inflammatory effect in the skin and a method of reducing skin inflammation through the oral consumption of the composition.
摘要翻译：适合于口服消耗的组合物，其包含黄豆苷原和花青素，其中黄豆苷原与花色素的重量比在1:1至1:100的范围内，其中黄豆苷原为预制的水分散体，并且其中所述组合物不含大豆蛋白，其可以在皮肤中表现出抗炎作用，使用含有黄豆苷原和花色素的组合物以获得皮肤中的抗炎作用，以及通过以下方法减少皮肤炎症口服消耗的组合物。

7. 发明申请

US20130101701A1 REHYDRATABLE FOOD 失效
标题翻译：可食用的食物
公开(公告)号：US20130101701A1
公开(公告)日：2013-04-25
申请号：US13698680
申请日：2011-05-25
申请人： Mark John Berry , John Casey , Ravine Anthony Gungabissoon , Andrew Paul Ormerod , Sally Pamela Redfern , Jacqueline de Silva , Joy Elizabeth Wilkinson
发明人： Mark John Berry , John Casey , Ravine Anthony Gungabissoon , Andrew Paul Ormerod , Sally Pamela Redfern , Jacqueline de Silva , Joy Elizabeth Wilkinson
IPC分类号： A23L1/212 , C12N15/82
CPC分类号： A23L1/212 , A23B7/02 , A23B7/022 , A23L19/00 , A23L19/01 , A23L33/17 , C12N15/8242
摘要： Use of dried rehydratable food, such as in a dried soup, a dried beverage, a breakfast cereal, a yoghurt and a dried sauce, is widespread. However it has been observed that when the dried components are fruit and/or vegetable, the components, on rehydration, do not resemble the fruit and/or vegetable before desiccation. That is to say they no longer have a fresh appearance but are discoloured and lack firmness. This transformation is due to cellular damage which occurs during desiccation. In particular, it is thought that phospholipid membranes are destabilised by insertion of cellular amphiphiles, phase transition into the gel phase and membrane fusion. This invention seeks to solve the above-mentioned technical problem by providing, amongst other things, a dried rehydratable food which is a fruit, vegetable or part thereof which, on rehydration, has improved appearance, texture and rehydration properties. In particular, a dried rehydratable food is provided, the food comprising less than 10% w/w water and at least 0.02% w/w of a dehydrin protein and derivatives thereof, the dehydrin protein and derivatives thereof comprising an amino acid sequence selected from the group consisting of K,I,K,E,K,L,P,G; K,I,K,E/D,K,L/I,P,G; and K,I,K,E/D,K,L/I/TA/,P/H/S,G, and wherein the dried rehydratable food is unbroken tissue of a vegetable or part thereof and/or a fruit or part thereof, and not a seed, wherein the unbroken tissue has a shortest linear dimension of at least 0.5 millimetres, preferably a shortest linear dimension of 0.5 to 25, more preferably 0.5 to 10 millimetres. A food product comprising the dried rehydratable food and methods for manufacturing the dried rehydratable food are also provided.
摘要翻译：使用干燥的可再水化食物，例如干燥的汤，干燥饮料，早餐谷物，酸奶和干酱，是广泛的。然而，已经观察到，当干燥的组分是水果和/或蔬菜时，在脱水之前，组分在干燥之前不类似于水果和/或植物。也就是说，他们不再有新鲜的外观，而是变色，缺乏坚定。这种转变是由于在干燥期间发生的细胞损伤。特别地，认为磷脂膜通过插入细胞两亲物，相转变成凝胶相和膜融合而不稳定。本发明寻求解决上述技术问题，其中除其他之外提供了一种水果，蔬菜或其一部分的干可再充水食品，其在再水合时具有改善的外观，质地和再水合性能。特别地，提供干燥的可再水化食物，该食品包含小于10％w / w水和至少0.02％w / w的脱水蛋白及其衍生物，脱水蛋白及其衍生物包含选自以下的氨基酸序列：由K，I，K，E，K，L，P，G组成的组; K，I，K，E / D，K，L / I，P，G; 和K，I，K，E / D，K，L / I / TA /，P / H / S，G，其中干燥的可再水化的食物是植物或其部分和/或水果或部分的未破碎的组织而不是种子，其中未断裂的组织具有至少0.5毫米的最短线性尺寸，优选最小直线尺寸为0.5至25，更优选为0.5至10毫米。还提供了包含干可再水化食品的食品和用于制造干可再水化食品的方法。

8. 发明申请

US20100215762A1 EDIBLE COMPOSITION FOR TREATING CUTANEOUS SIGNS OF AGEING 有权
标题翻译：用于处理老化迹象的食用组合物
公开(公告)号：US20100215762A1
公开(公告)日：2010-08-26
申请号：US12707706
申请日：2010-02-18
申请人： John Casey , Gail Jenkins , Linda Jane Wainwright
发明人： John Casey , Gail Jenkins , Linda Jane Wainwright
IPC分类号： A61K35/20 , A61K31/352
CPC分类号： A61K8/97 , A23L33/105 , A23V2002/00 , A61K8/02 , A61K8/345 , A61K8/49 , A61K8/498 , A61K2800/92 , A61Q19/08 , A23V2200/318 , A23V2250/21
摘要： This invention relates to the provision of an edible composition for the treatment of cutaneous signs of ageing, in particular those associated with loss of skin elasticity, wrinkles and sagging. Thus the inventive composition provides skin benefits selected from the group consisting of enhancing collagen deposition in the skin, reducing the appearance of wrinkles and reducing sagging. Thus the invention provides an edible composition for treating aged skin, the composition comprising: (a) 2 to 1000, preferably 5 to 750, most preferably 10 to 500 mg anthocyanidin and derivatives thereof; and (b) 1 to 20, preferably 5 to 15, most preferably 2 to 10 mg lutein and derivatives thereof; wherein the weight ratio of anthocyanidin to lutein is at least 1:1, preferably at least 10:1 and more preferably at least 25:1, even more preferably at least 50:1, most preferably at least 100:1; wherein the composition excludes copper in the form of separately or in combination copper gluconate and copper oxide; and further excludes separately or in combination with the copper exclusion Nandina domestica or an extract thereof. The invention also relates to a cosmetic method for providing the aforesaid skin benefits using the inventive composition.
摘要翻译：本发明涉及提供用于治疗皮肤老化症状的可食用组合物，特别是与皮肤弹性丧失，皱纹和下垂相关的可食性组合物。因此，本发明的组合物提供选自由增强皮肤中的胶原沉积，减少皱纹的外观和减少下垂的皮肤的益处。因此，本发明提供了一种用于治疗老化皮肤的可食用组合物，所述组合物包含：（a）2至1000，优选5至750，最优选10至500mg花色素及其衍生物; 和（b）1至20，优选5至15，最优选2至10mg叶黄素及其衍生物; 其中花青素与叶黄素的重量比为至少1:1，优选至少10:1，更优选至少25:1，甚至更优选至少50:1，最优选至少100:1; 其中所述组合物以单独或组合的葡萄糖酸铜和氧化铜的形式排除铜; 并且进一步排除或者与铜排除Nandina domestica或其提取物组合。本发明还涉及使用本发明组合物提供上述皮肤益处的美容方法。

9. 发明申请

US20070113078A1 System and method for encrypting data without regard to application 有权
标题翻译：用于加密数据而不考虑应用的系统和方法
公开(公告)号：US20070113078A1
公开(公告)日：2007-05-17
申请号：US11406175
申请日：2006-04-18
申请人： Russell Witt , Timothy Bruce , David Helsley , Osvaldo Ridner , John Casey
发明人： Russell Witt , Timothy Bruce , David Helsley , Osvaldo Ridner , John Casey
IPC分类号： H04L9/00
CPC分类号： G06F21/78 , G06F21/602
摘要： Systems and methods are provided for encrypting data without regard to applications writing the data to, or reading the data from, encrypted data storage devices. An operating system intercept detects information indicating that a file will be encrypted and, in respond, sets device-level flags indicating encryption and also establishes one or more encryption keys to be used in the encryption process. A second intercept detects an input/output event and, in response, calls an encryption application to encrypt (or decrypt) the data before it is written to (or read from) the data storage device.
摘要翻译：提供用于加密数据的系统和方法，而不考虑将数据写入加密数据存储设备或从加密数据存储设备读取数据的应用。操作系统拦截检测指示文件将被加密的信息，并且在响应中设置指示加密的设备级标志，并且还建立要在加密过程中使用的一个或多个加密密钥。第二个拦截检测输入/输出事件，作为响应，调用加密应用程序在将数据写入数据存储设备（或从其读取）之前加密（或解密）数据。

10. 发明授权

US06908674B2 Jadeite and its production 失效
标题翻译：翡翠及其生产
公开(公告)号：US06908674B2
公开(公告)日：2005-06-21
申请号：US09799192
申请日：2001-03-05
申请人： Suresh Shankarappa Vagarali , Thomas Richard Anthony , John Casey , Robert Charles DeVries , Stephen Lee Dole , John William Lucek , Alan Cameron Smith , Biju Varghese , Steven William Webb
发明人： Suresh Shankarappa Vagarali , Thomas Richard Anthony , John Casey , Robert Charles DeVries , Stephen Lee Dole , John William Lucek , Alan Cameron Smith , Biju Varghese , Steven William Webb
IPC分类号： B01J3/06 , C01B33/20 , C01B33/26 , B32B5/16
CPC分类号： C01B33/26 , B01J3/062 , B01J2203/068 , C01B33/20 , Y10T428/2982 , Y10T428/2996
摘要： A jadeite material has a thickness in excess of about 1.0 mm and CIELAB indices of L*>42, a* +6. The grain size of the jadeite material is less than about 30 microns and is an equiaxed grain structure. The jadeite material has an optical transmission peak between 500 and 565 nm with an I/IO optical transmission ratio of over 40%. The first step in making the jadeite material is to wrap a glass block, convertible by HP/HT into jadeite and having a nominal composition of NaAlSi2O6, with a graphite or refractive metal sheet. The wrapped glass block is placed in an HP/HT apparatus, rapidly heated, and subjected therein to a pressure in excess of about 3 GPa and a temperature in excess of about 1000° C. for a time adequate to convert the glass block into jadeite. The jadeite material then is cooled and the pressure subsequently released.
摘要翻译：翡翠材料的厚度超过约1.0mm，CIELAB指数L *> 42，a * <-6和b *> + 6。翡翠材料的晶粒尺寸小于约30微米，是等轴晶粒结构。翡翠材料具有在500和565nm之间的光传输峰值，其中I / I / O光透射率超过40％。制造翡翠材料的第一步是将玻璃块包裹，由HP / HT转化为翡翠，并具有标称组成的NaAlSi 2 O 6 6，与石墨或折射金属片。将包裹的玻璃块放置在HP / HT装置中，快速加热，并在其中进行超过约3GPa的压力和超过约1000℃的温度，足以将玻璃块转化成翡翠。然后将翡翠材料冷却并随后释放压力。

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