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1. 发明授权

US08809395B2 Methods for making valerenic acid derivatives and their use 有权
标题翻译：制备戊酸衍生物的方法及其用途
公开(公告)号：US08809395B2
公开(公告)日：2014-08-19
申请号：US13138227
申请日：2010-01-22
申请人： Johann Mulzer , Jürgen Ramharter , Steffen Hering , Sophia Khom
发明人： Johann Mulzer , Jürgen Ramharter , Steffen Hering , Sophia Khom
IPC分类号： A61K31/16 , C07C233/02 , C07C233/10 , C07C233/16 , C07C243/32 , C07C231/02
CPC分类号： C07C69/608 , A61K31/16 , C07C29/42 , C07C57/26 , C07C69/732 , C07C231/02 , C07C233/02 , C07C233/10 , C07C233/16 , C07C243/32 , C07C2602/24 , C07D307/93
摘要： The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABAA receptor ligands.
摘要翻译：本发明涉及制备戊酰酸及其衍生物的化合物，中间体和方法以及这些化合物如GABA A受体配体的用途。

2. 发明申请

US20120022283A1 METHODS FOR MAKING VALERENIC ACID DERIVATIVES AND THEIR USE 有权
标题翻译：制备戊酸衍生物及其用途的方法
公开(公告)号：US20120022283A1
公开(公告)日：2012-01-26
申请号：US13138227
申请日：2010-01-22
申请人： Johann Mulzer , Jürgen Ramharter , Steffen Hering , Sophia Khom
发明人： Johann Mulzer , Jürgen Ramharter , Steffen Hering , Sophia Khom
IPC分类号： C07C57/26 , C07C69/732
CPC分类号： C07C69/608 , A61K31/16 , C07C29/42 , C07C57/26 , C07C69/732 , C07C231/02 , C07C233/02 , C07C233/10 , C07C233/16 , C07C243/32 , C07C2602/24 , C07D307/93
摘要： The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABAA receptor ligands.
摘要翻译：本发明涉及制备戊酰酸及其衍生物的化合物，中间体和方法以及这些化合物如GABA A受体配体的用途。

3. 发明申请

US20150045574A1 METHODS FOR MAKING VALERENIC ACID DERIVATIVES AND THEIR USE 审中-公开
标题翻译：制备戊酸衍生物及其用途的方法
公开(公告)号：US20150045574A1
公开(公告)日：2015-02-12
申请号：US14335229
申请日：2014-07-18
申请人： Johann Mulzer , Jurgen Ramharter , Steffen Hering , Sophia Khom
发明人： Johann Mulzer , Jurgen Ramharter , Steffen Hering , Sophia Khom
IPC分类号： C07C69/608 , C07C57/26 , C07D307/93 , C07C69/732 , C07C29/42
CPC分类号： C07C69/608 , A61K31/16 , C07C29/42 , C07C57/26 , C07C69/732 , C07C231/02 , C07C233/02 , C07C233/10 , C07C233/16 , C07C243/32 , C07C2602/24 , C07D307/93
摘要： The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABAA receptor ligands.
摘要翻译：本发明涉及制备戊酰酸及其衍生物的化合物，中间体和方法以及这些化合物如GABA A受体配体的用途。

4. 发明授权

US6146881A Device and method for handling objects in a liquid bath 失效
标题翻译：在液体浴中处理物体的装置和方法
公开(公告)号：US6146881A
公开(公告)日：2000-11-14
申请号：US160025
申请日：1998-09-24
申请人： Steffen Hering
发明人： Steffen Hering
IPC分类号： B01L3/02 , G01N1/34 , A01N1/00
CPC分类号： G01N1/34 , B01L3/0275 , B01L3/508 , C12M23/12 , C12M23/34 , C12M29/10 , C12M33/04 , B01L2200/026 , B01L2200/0689 , G01N2001/4016
摘要： In an apparatus used for perfusion-treating objects within a defined treatment area of a liquid bath, the apparatus having a ring having a lower edge which is sealingly placeable on the bottom of the liquid bath and an interior for connection to a liquid conveying device. The ring includes a holding member for receiving an inlet member of the liquid conveying device, or a wall having at least one wall chamber which communicates with the holding member on the ring and with the interior of the ring.
摘要翻译：在用于在液槽的限定处理区域内对物体进行灌注处理的设备中，所述设备具有环，所述环具有密封地放置在液槽底部的下边缘和用于连接到液体输送装置的内部。环包括用于接收液体输送装置的入口构件的保持构件或具有至少一个壁室的壁，该壁室与环上的保持构件和环的内部连通。

5. 发明申请

US20100041093A1 DEVICES AND METHOD FOR ELECTROPHYSICAL CELL ANALYSES 审中-公开
标题翻译：用于电生理细胞分析的装置和方法
公开(公告)号：US20100041093A1
公开(公告)日：2010-02-18
申请号：US12513683
申请日：2007-10-31
申请人： Steffen Hering
发明人： Steffen Hering
IPC分类号： C12Q1/02 , C12M1/00 , C12M1/34
CPC分类号： G01N33/48728
摘要： Disclosed is a liquid holder mechanism (10) which is designed to form a liquid environment at a capillary tip (22) of a patch clamp pipette (20) and includes a holding element (11.2) for retaining a liquid drop (1) and at least one rod (12.2, 12.3) for positioning the holding element (11.2) on the capillary tip (22). The at least one rod (12.2, 12.3) is designed such that the holding element (11.2) can be separated from the capillary (21) in a state in which the liquid holder mechanism (10) is connected to the patch clamp pipette (20). Also disclosed are a measuring instrument that is equipped with said liquid holder mechanism (10) as well as a method for electrophysically analyzing a biological cell with the help of the liquid holder mechanism (10).
摘要翻译：公开了一种液体保持器机构（10），其设计成在膜片钳移液管（20）的毛细管尖端（22）处形成液体环境，并且包括用于保持液滴（1）的保持元件（11.2）用于将保持元件（11.2）定位在毛细管尖端（22）上的至少一个杆（12.2,12.3）。至少一个杆（12.2,12.3）被设计成使得保持元件（11.2）可以在液体保持器机构（10）连接到膜片钳移液管（20）的状态下与毛细管（21）分离）。还公开了配备有所述液体保持器机构（10）的测量仪器以及借助于液体保持器机构（10）电生物分析生物细胞的方法。

6. 发明申请

US20070231879A1 Perfusion device for the treatment and examination of an object in a liquid 审中-公开
标题翻译：用于处理和检查液体中物体的灌注装置
公开(公告)号：US20070231879A1
公开(公告)日：2007-10-04
申请号：US11393226
申请日：2006-03-30
申请人： Steffen Hering , Sascha Hering
发明人： Steffen Hering , Sascha Hering
IPC分类号： C12M1/34
CPC分类号： C12M41/36 , C12M29/10
摘要： A perfusion device (10) is described, particularly for electro-physiological and/or optical examinations on biological objects (1) which comprises a chamber body (20) in which a perfusion chamber (21, 25) is formed with at least one input opening (22, 23) and at least one discharge (24), and a holding device (30) for holding at least one object (1) to be examined in the perfusion chamber, the holding device (30) comprising a projection that forms a seat (31) on its upper end for the object (1) to be examined and is level-adjustably arranged in the perfusion chamber (21, 25) and, if the holding device (30) protrudes into the perfusion chamber (21, 25), a circumferential perfusion gap (25) being formed laterally and relative to the chamber body (20), which gap is connected to the discharge (24).
摘要翻译：描述了一种灌注装置（10），特别是用于生物体（1）上的电生理和/或光学检查，其包括腔室主体（20），其中灌注腔室（21,25）形成有至少一个输入开口（22,23）和至少一个排出口（24）以及用于保持至少一个被检查物体（1）的灌注室中的保持装置（30），所述保持装置（30）包括形成位于其上端的用于被检查物体（1）的座（31），并且可调节地布置在灌注腔（21,25）中，并且如果保持装置（30）突出到灌注腔（21）中， 25），横向和相对于腔室主体（20）形成的周向灌注间隙（25），该间隙连接到排出口（24）。

7. 发明授权

US07811265B2 Ultrasonic probe with positioning device for examination devices and operation devices 有权
标题翻译：超声波探头具有检测装置和操作装置的定位装置
公开(公告)号：US07811265B2
公开(公告)日：2010-10-12
申请号：US10432642
申请日：2001-11-21
申请人： Steffen Hering , Rainer Marksteiner , Hannes Strasser
发明人： Steffen Hering , Rainer Marksteiner , Hannes Strasser
IPC分类号： A61M5/00
CPC分类号： A61B8/12
摘要： An ultrasonic probe with an ultrasonic head (K), which is arranged on or in a shaft (S) and is moveable with or in this shaft, and a positioning apparatus (P) for at least one examination or operating device is described, which is connected with the shaft. Also, medical operating apparatuses with examination probes and uses of the ultrasonic probe and the medical implements are described.
摘要翻译：一种具有超声波头（K）的超声波探头（K），其布置在轴（S）上或其中，并且可与该轴一起移动或在该轴中移动，以及用于至少一个检查或操作装置的定位装置（P）与轴连接。此外，还描述了具有检查探针和超声波探头和医疗器具的用途的医疗操作装置。

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