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1. 发明授权

US06540734B1 Multi-lumen extrusion tubing 有权
标题翻译：多腔挤出管
公开(公告)号：US06540734B1
公开(公告)日：2003-04-01
申请号：US09505616
申请日：2000-02-16
申请人： Jessica Chiu , Paul Reiss , Mark Newton , Eric D. Peterson
发明人： Jessica Chiu , Paul Reiss , Mark Newton , Eric D. Peterson
IPC分类号： A61M2500
CPC分类号： A61M25/1011 , A61M25/0029 , A61M25/1027 , A61M25/1029 , A61M25/1034 , A61M25/1038 , A61M2025/0036 , A61M2025/004 , A61M2025/1047 , A61M2025/1097 , A61N5/1002 , A61N2005/1003
摘要： A multi-lumen balloon for use in a fluted balloon centering catheter and method for providing the same. The multi-lumen balloon maintains a radiation source at the center of a cardiovascular artery, has improved blood perfusion capability, and has improved balloon refolding characteristics. The method of fabricating a multi-lumen balloon designed for a radiation centering catheter uses an improved extrusion process that allows the manufacture of the multi-lumen balloon sub-assembly to be done separately from the catheter shaft assembly.
摘要翻译：用于槽纹气球定心导管的多腔气囊及其提供方法。多腔气球在心血管动脉中心保持辐射源，具有改善的血液灌注能力，并且具有改善的气球重折叠特性。制造针对放射定心导管设计的多腔气囊的方法使用改进的挤出方法，其允许制造与导管轴组件分离的多腔气囊子组件。

2. 发明授权

US07163504B1 Multi-lumen fluted balloon radiation centering catheter 有权
标题翻译：多腔凹槽气球辐射定心导管
公开(公告)号：US07163504B1
公开(公告)日：2007-01-16
申请号：US09506081
申请日：2000-02-16
申请人： Jessica Chiu , Manolo F. Lumauig , Eric D. Peterson
发明人： Jessica Chiu , Manolo F. Lumauig , Eric D. Peterson
IPC分类号： A61N5/00
CPC分类号： A61M25/1011 , A61M25/0029 , A61M25/1027 , A61M25/1029 , A61M25/1034 , A61M25/1038 , A61M2025/0036 , A61M2025/004 , A61M2025/1047 , A61M2025/1097 , A61N5/1002 , A61N2005/1003
摘要： A multi-lumen balloon for use in a fluted balloon centering catheter and method for providing the same. The multi-lumen balloon maintains a radiation source at the center of a cardiovascular artery, has improved blood perfusion capability, and has improved balloon refolding characteristics. The method of fabricating a multi-lumen balloon designed for a radiation centering catheter uses an improved extrusion process that allows the manufacture of the multi-lumen balloon sub-assembly to be done separately from the catheter shaft assembly.
摘要翻译：用于槽纹气球定心导管的多腔气囊及其提供方法。多腔气球在心血管动脉的中心保持辐射源，具有改善的血液灌注能力，并且具有改善的气球重折叠特性。制造针对放射定心导管设计的多腔气囊的方法使用改进的挤出方法，其允许制造与导管轴组件分离的多腔气囊子组件。

3. 发明授权

US08182463B2 Retrograde pressure regulated infusion 有权
标题翻译：逆行压力调节输液
公开(公告)号：US08182463B2
公开(公告)日：2012-05-22
申请号：US11609143
申请日：2006-12-11
申请人： Jessica Chiu , Gregory Waimong Chan , Hongzhi Bai , Nianjiong J. Bei , Mark J. Bly , Srinivasan Sridharan , Tom Hatten
发明人： Jessica Chiu , Gregory Waimong Chan , Hongzhi Bai , Nianjiong J. Bei , Mark J. Bly , Srinivasan Sridharan , Tom Hatten
IPC分类号： A61M31/00
CPC分类号： A61M25/10 , A61M25/1002 , A61M2025/1052
摘要： A delivery catheter that includes a flexible shaft having a proximal end and a distal end, the distal end having an outer diameter less than about 13 mm; a delivery lumen having a proximal end and a distal end, the delivery lumen within the flexible shaft, the delivery lumen having at least an outlet port or at least one side hole at the distal end of the delivery lumen, the delivery lumen having a cross-sectional area at least about 5 mm2; a pressure monitoring lumen having a proximal end and a distal end, the pressure monitoring lumen within the flexible shaft; a pressure port adjacent to and connected to the distal end of the pressure monitoring lumen; a balloon inflation lumen having a proximal end and a distal end, the balloon inflation lumen within the flexible shaft; a soft tip at the distal end of the flexible shaft; a balloon at the distal end of the flexible shaft, the balloon connected to the distal end of the balloon inflation lumen, the balloon includes at least one of the following materials, polyether block amide resin, polyetheramide, polyurethane, silicone, natural latex, or synthetic latex; wherein the balloon is adapted to inflate to a diameter range of about 4 to about 15 mm.
摘要翻译：输送导管，其包括具有近端和远端的柔性轴，所述远端具有小于约13mm的外径; 输送腔，其具有近端和远端，所述输送腔在所述柔性轴内，所述输送腔至少具有出口端口或至少一个在所述输送腔的远端处的侧孔，所述输送腔具有交叉截面面积至少约5 mm2; 具有近端和远端的压力监测管腔，所述柔性轴内的所述压力监测腔; 与所述压力监视管腔的远端相邻并连接的压力口; 具有近端和远端的球囊充气腔，所述气囊膨胀腔在所述柔性轴内; 在柔性轴的远端处的软尖端; 在柔性轴的远端处的气囊，气囊连接到球囊充气腔的远端，气囊包括以下材料中的至少一种：聚醚嵌段酰胺树脂，聚醚酰胺，聚氨酯，硅氧烷，天然胶乳或合成胶乳其中所述气囊适于膨胀至约4至约15mm的直径范围。

4. 发明授权

US07250041B2 Retrograde pressure regulated infusion 有权
标题翻译：逆行压力调节输液
公开(公告)号：US07250041B2
公开(公告)日：2007-07-31
申请号：US10387048
申请日：2003-03-12
申请人： Jessica Chiu , Gregory Waimong Chan , Hongzhi Bai , Nianjiong J. Bei , Mark J. Bly , Srinivasan Sridharan , Tom Hatten
发明人： Jessica Chiu , Gregory Waimong Chan , Hongzhi Bai , Nianjiong J. Bei , Mark J. Bly , Srinivasan Sridharan , Tom Hatten
IPC分类号： A61M25/00
CPC分类号： A61M25/10 , A61M25/1002 , A61M2025/1052
摘要： A delivery catheter that includes a flexible shaft having a proximal end and a distal end, the distal end having an outer diameter less than about 13 mm; a delivery lumen having a proximal end and a distal end, the delivery lumen within the flexible shaft, the delivery lumen having at least an outlet port or at least one side hole at the distal end of the delivery lumen, the delivery lumen having a cross-sectional area at least about 5 mm2; a pressure monitoring lumen having a proximal end and a distal end, the pressure monitoring lumen within the flexible shaft; a pressure port adjacent to and connected to the distal end of the pressure monitoring lumen; a balloon inflation lumen having a proximal end and a distal end, the balloon inflation lumen within the flexible shaft; a soft tip at the distal end of the flexible shaft; a balloon at the distal end of the flexible shaft, the balloon connected to the distal end of the balloon inflation lumen, the balloon includes at least one of the following materials, polyether block amide resin, polyetheramide, polyurethane, silicone, natural latex, or synthetic latex; wherein the balloon is adapted to inflate to a diameter range of about 4 to about 15 mm.
摘要翻译：输送导管，其包括具有近端和远端的柔性轴，所述远端具有小于约13mm的外径; 输送腔，其具有近端和远端，所述输送腔在所述柔性轴内，所述输送腔至少具有出口端口或至少一个在所述输送腔的远端处的侧孔，所述输送腔具有交叉至少约5毫米2的截面积; 具有近端和远端的压力监测管腔，所述柔性轴内的所述压力监测腔; 与所述压力监视管腔的远端相邻并连接的压力口; 具有近端和远端的球囊充气腔，所述气囊膨胀腔在所述柔性轴内; 在柔性轴的远端处的软尖端; 在柔性轴的远端处的气囊，气囊连接到球囊充气腔的远端，气囊包括以下材料中的至少一种：聚醚嵌段酰胺树脂，聚醚酰胺，聚氨酯，硅氧烷，天然胶乳或合成胶乳其中所述气囊适于膨胀至约4至约15mm的直径范围。

5. 发明授权

US06666880B1 Method and system for securing a coated stent to a balloon catheter 有权
标题翻译：用于将涂覆的支架固定到球囊导管的方法和系统
公开(公告)号：US06666880B1
公开(公告)日：2003-12-23
申请号：US09885594
申请日：2001-06-19
申请人： Jessica Chiu , Keith Edward Fong
发明人： Jessica Chiu , Keith Edward Fong
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2002/9583 , A61F2250/0067
摘要： A method for mounting coated stents on balloon catheters uses a sheath and a pressurized fluid to expand the balloon. Heat is applied only at the ends of the balloon. An insulating disk and a chill block prevent overheating of the temperature sensitive stent coatings.
摘要翻译：将涂覆的支架安装在球囊导管上的方法使用护套和加压流体来膨胀气囊。仅在气球的末端施加热量。绝缘盘和冷却块可防止温度敏感的支架涂层过热。

6. 发明申请

US20080103523A1 INFUSION TREATMENT AGENTS, CATHETERS, FILTER DEVICES, AND OCCLUSION DEVICES, AND USE THEREOF 审中-公开
公开(公告)号：US20080103523A1
公开(公告)日：2008-05-01
申请号：US11923332
申请日：2007-10-24
申请人： Jessica Chiu , Gregory Chan , Gabriel Asongwe , Robert Esselstein , Douglas Gesswein , Srinivasan Sridharan , Nianjiong Bei , William Webler , Stephen Schaible , Mina Chow , Yan Shen , Hongzhi Bai , Mark Bly , Thomas Hatten
发明人： Jessica Chiu , Gregory Chan , Gabriel Asongwe , Robert Esselstein , Douglas Gesswein , Srinivasan Sridharan , Nianjiong Bei , William Webler , Stephen Schaible , Mina Chow , Yan Shen , Hongzhi Bai , Mark Bly , Thomas Hatten
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61M25/1002 , A61M2025/1052
摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

7. 发明申请

US20050211679A1 Square-wave laser bonding 有权
标题翻译：方波激光键合
公开(公告)号：US20050211679A1
公开(公告)日：2005-09-29
申请号：US11137869
申请日：2005-05-25
申请人： Jessica Chiu , Lara Suh , Arthur Wen
发明人： Jessica Chiu , Lara Suh , Arthur Wen
IPC分类号： A61M25/00 , B23K26/00 , B23K26/08
CPC分类号： B23K26/083 , A61M25/1034 , A61M25/1036 , B23K26/0823
摘要： The present invention provides a square-wave laser seal pattern made by first directing a laser beam onto an shaft while the shaft is moving in a horizontal direction relative to a laser device so as to create a horizontal laser seal bond segment. Next, with the shaft rotating about a shaft longitudinal axis, the laser beam is directed onto the shaft so as to create a vertical laser seal bond segment. By alternately creating and coupling together a plurality of horizontal and vertical laser seal bond segments, a square-wave laser seal is formed around a circumference of the shaft. The shaft's movement in a horizontal direction relative to a laser beam may be either at a constant speed or a variable speed so as to control the amount of laser energy heat impacting the shaft material.
摘要翻译：本发明提供了一种方波激光密封图案，其通过首先将激光束引导到轴上，同时轴相对于激光装置沿水平方向移动，以便产生水平的激光密封接合段。接下来，随着轴围绕轴纵向轴线旋转，激光束被引导到轴上，以便产生垂直激光密封接合段。通过交替地将多个水平和垂直的激光密封接合段相互创建和耦合在一起，在轴的圆周周围形成方波激光密封。轴相对于激光束在水平方向的移动可以是恒定速度或可变速度，以便控制冲击轴材料的激光能量的热量。

8. 发明申请

US20050070844A1 Deflectable catheter assembly and method of making same 有权
标题翻译：可挠性导管组件及其制作方法
公开(公告)号：US20050070844A1
公开(公告)日：2005-03-31
申请号：US10676616
申请日：2003-09-30
申请人： Mina Chow , Barbara Stamberg , William Webler , John Simpson , August Yambao , Gabriel Asongwe , Jessica Chiu , Lili Liu , Dagmar Beyerlein
发明人： Mina Chow , Barbara Stamberg , William Webler , John Simpson , August Yambao , Gabriel Asongwe , Jessica Chiu , Lili Liu , Dagmar Beyerlein
IPC分类号： A61M25/00 , A61M25/01 , A61M31/00
CPC分类号： A61M25/0136 , A61M25/0012 , A61M25/0013 , A61M25/0029 , A61M25/005 , A61M25/0051 , A61M25/0054 , A61M25/0138 , A61M25/0147 , A61M25/0152 , A61M2025/004 , A61M2025/0063 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/015
摘要： A deflectable catheter assembly is disclosed. The assembly comprises a catheter shaft having a catheter proximal section and a catheter distal section, and at least one lumen extending therethrough. The catheter distal section is more flexible than the catheter proximal section. A tendon is disposed within a first lumen of said catheter shaft. The first lumen is approximately centrally located within the catheter shaft at the catheter proximal section. The first lumen is located off-center of the catheter shaft at the catheter distal section. The tendon is able to deflect the catheter distal section when being pulled on. A catheter handle is coupled to the catheter shaft at the catheter proximal section, the catheter handle includes a control mechanism to control the tendon.
摘要翻译：公开了一种可偏转导管组件。组件包括具有导管近端部分和导管远端部分的导管轴和延伸穿过其中的至少一个内腔。导管远端部分比导管近端部分更灵活。腱设置在所述导管轴的第一内腔内。导管近端部分处的第一管腔大致位于导管轴的中心。第一管腔位于导管远端部处的导管轴的中心。当被拉扯时，肌腱能够使导管远端部分偏转。导管手柄在导管近端部分处联接到导管轴，导管手柄包括用于控制腱的控制机构。

9. 发明授权

US07994449B2 Square-wave laser bonding 有权
标题翻译：方波激光键合
公开(公告)号：US07994449B2
公开(公告)日：2011-08-09
申请号：US11137869
申请日：2005-05-25
申请人： Jessica Chiu , Lara K. Suh , Arthur Wen
发明人： Jessica Chiu , Lara K. Suh , Arthur Wen
IPC分类号： B23K26/00
CPC分类号： B23K26/083 , A61M25/1034 , A61M25/1036 , B23K26/0823
摘要： The present invention provides a square-wave laser seal pattern made by first directing a laser beam onto an shaft while the shaft is moving in a horizontal direction relative to a laser device so as to create a horizontal laser seal bond segment. Next, with the shaft rotating about a shaft longitudinal axis, the laser beam is directed onto the shaft so as to create a vertical laser seal bond segment. By alternately creating and coupling together a plurality of horizontal and vertical laser seal bond segments, a square-wave laser seal is formed around a circumference of the shaft. The shaft's movement in a horizontal direction relative to a laser beam may be either at a constant speed or a variable speed so as to control the amount of laser energy heat impacting the shaft material.
摘要翻译：本发明提供了一种方波激光密封图案，其通过首先将激光束引导到轴上，同时轴相对于激光装置沿水平方向移动，以便产生水平的激光密封接合段。接下来，随着轴围绕轴纵向轴线旋转，激光束被引导到轴上，以便产生垂直激光密封接合段。通过交替地将多个水平和垂直的激光密封接合段相互创建和耦合在一起，在轴的圆周周围形成方波激光密封。轴相对于激光束在水平方向的移动可以是恒定速度或可变速度，以便控制冲击轴材料的激光能量的热量。

10. 发明申请

US20080103478A1 INFUSION TREATMENT AGENTS, CATHETERS, FILTER DEVICES, AND OCCLUSION DEVICES, AND USE THEREOF 审中-公开
公开(公告)号：US20080103478A1
公开(公告)日：2008-05-01
申请号：US11923068
申请日：2007-10-24
申请人： Jessica Chiu , Gregory Chan , Gabriel Asongwe , Robert Esselstein , Douglas Gesswein , Srinivasan Sridharan , Nianjiong Bei , William Webler , Stephen Schaible , Mina Chow , Yan Shen , Hongzhi Bai , Mark Bly , Thomas Hatten
发明人： Jessica Chiu , Gregory Chan , Gabriel Asongwe , Robert Esselstein , Douglas Gesswein , Srinivasan Sridharan , Nianjiong Bei , William Webler , Stephen Schaible , Mina Chow , Yan Shen , Hongzhi Bai , Mark Bly , Thomas Hatten
IPC分类号： A61M31/00 , A61M25/10
CPC分类号： A61M25/10 , A61M25/1002 , A61M2025/1052
摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

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