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1. 发明授权

US09173759B2 Devices and methods for gastrointestinal bypass 有权
公开(公告)号：US09173759B2
公开(公告)日：2015-11-03
申请号：US13485898
申请日：2012-05-31
申请人： Jesse N. Nelson , Justin Schwab
发明人： Jesse N. Nelson , Justin Schwab
IPC分类号： A61M5/00 , A61F5/00 , A61B17/11 , A61F2/04 , A61B17/064 , A61B17/068 , A61B19/00 , A61B17/04 , A61B17/00 , A61B17/06
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/064 , A61B17/068 , A61B17/1114 , A61B90/39 , A61B2017/00818 , A61B2017/0404 , A61B2017/0409 , A61B2017/0419 , A61B2017/0464 , A61B2017/047 , A61B2017/06052 , A61B2017/0647 , A61B2090/3908 , A61B2090/395 , A61B2090/3966 , A61F2/04 , A61F5/0036 , A61F5/0079 , A61F5/0089 , A61F2002/045 , A61F2250/0097
摘要： Devices and methods for gastrointestinal bypass are described. A gastrointestinal bypass device includes a gastrointestinal cuff and a gastrointestinal sleeve. The cuff may be configured to be attached in the esophagus, and may be sufficiently flexible to expand and collapse to conform with the inside of the esophagus to allow the esophagus to function substantially normally. The sleeve is configured to be coupled to the cuff, and may be made of a material that is floppy or flaccid but does not substantially expand radially.

2. 发明授权

US09199069B2 Implantable injection port 有权
标题翻译：可植入注射口
公开(公告)号：US09199069B2
公开(公告)日：2015-12-01
申请号：US13277802
申请日：2011-10-20
申请人： Ethan Franklin , Justin Schwab , Zachary P. Dominguez
发明人： Ethan Franklin , Justin Schwab , Zachary P. Dominguez
IPC分类号： A61M39/04 , A61M39/02 , A61M39/00 , A61F5/00
CPC分类号： A61M39/0208 , A61F5/0056 , A61M2039/0063 , A61M2039/0072 , Y10T156/1005
摘要： Injection ports are disclosed for use with a gastric band for the treatment of obesity. An injection port may include a septum having a top surface, a bottom surface, and a side wall connecting the top surface to the bottom surface. The injection port may also include a housing including a first inner side wall being tapered inwards such that an opening defined at a first end is larger than an opening defined at a second end, the tapering of the first inner side wall being used to secure the septum within the housing. The housing may further include a second inner side wall having a first end and a second end, the first end of the second inner side wall joined to the second end of the first inner side wall, and a bottom surface joined to the second end of the second inner side wall.
摘要翻译：公开了与胃带一起用于治疗肥胖症的注射口。注射口可以包括具有顶表面，底表面和连接顶表面和底表面的侧壁的隔膜。注入口还可以包括壳体，其包括向内锥形的第一内侧壁，使得限定在第一端处的开口大于限定在第二端处的开口，第一内侧壁的锥形用于固定房屋内的隔膜壳体还可以包括具有第一端和第二端的第二内侧壁，第二内侧壁的第一端连接到第一内侧壁的第二端，并且底表面连接到第二端第二内侧壁。

3. 发明授权

US08864840B2 Intragastric implants with collapsible frames 有权
标题翻译：具有可折叠框架的内部植入物
公开(公告)号：US08864840B2
公开(公告)日：2014-10-21
申请号：US13272131
申请日：2011-10-12
申请人： Zachary Dominguez , Mitchell H. Babkes , Justin Schwab , Christopher S. Mudd , Jason Hoover
发明人： Zachary Dominguez , Mitchell H. Babkes , Justin Schwab , Christopher S. Mudd , Jason Hoover
IPC分类号： A61F2/04
CPC分类号： A61F5/0036 , A61F5/0033 , A61F5/0079 , A61F5/0086 , A61F5/0089
摘要： Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.
摘要翻译：描述了跨腹部肥胖症治疗装置及其相关操作方法，其占据胃内的空间和/或刺激胃壁。经腹肥胖治疗装置和相关方法旨在帮助患者保持健康的体重。器件的特征包括经皮插入和无侵入性手术，无相关患者的侵入性手术风险，无明显的患者不适。这些装置的使用寿命可能依赖于酸性胃内的长期生存能力，但意图持续一年或更长时间。这些装置具有在尺寸上变化的能力，并且希望是自动致动，因为它们使用内部电动机或致动器改变形状和/或体积。设备的变化特征有助于防止人的胃部补偿植入物，例如有时会发生静态胃内装置。

4. 发明授权

US08821373B2 Directionless (orientation independent) needle injection port 有权
标题翻译：无方向（取向独立）针头注射口
公开(公告)号：US08821373B2
公开(公告)日：2014-09-02
申请号：US13104260
申请日：2011-05-10
申请人： Justin Schwab , Sean Snow
发明人： Justin Schwab , Sean Snow
IPC分类号： A61F13/00 , A61B17/00
CPC分类号： A61F5/0056 , A61F5/0043 , A61M39/0208 , A61M2039/022 , A61M2039/0226 , A61M2039/0238
摘要： Generally described herein are certain embodiments directed to an orientation-independent injection port fluidly coupled to a gastric banding system. The injection port may be configured to simplify the port-targeting process when a medical professional attempts to penetrate the injection port with a needle during a gastric band-adjusting procedure. For example, the injection port may be orientation-independent with the entire outer shell acting as the needle access point. Alternatively, and/or in addition, the inner core of the injection port may be hard or firm, thereby allowing for easier locating (e.g., when the medical professional performs palpation). Furthermore, the hard inner core may prevent needle over-throws, and help stabilize pressure.
摘要翻译：本文通常描述的是针对流体耦合到胃束带系统的取向非依赖性注射端口的某些实施方案。注射端口可以被配置为当医疗专业人员在胃束带调整过程期间试图用针穿透注射端口时，简化端口定位过程。例如，注射口可以是取向独立的，整个外壳用作针入口点。或者，和/或另外，注射口的内芯可以是硬的或坚固的，从而允许更容易的定位（例如当医疗专业人员进行触诊时）。此外，硬内芯可以防止针头过度投掷，并有助于稳定压力。

5. 发明申请

US20120095494A1 INTRAGASTRIC IMPLANTS WITH COLLAPSIBLE FRAMES 有权
标题翻译：具有可拉框的INTRAGASTRIC植入物
公开(公告)号：US20120095494A1
公开(公告)日：2012-04-19
申请号：US13272131
申请日：2011-10-12
申请人： Zachary Dominguez , Mitchell H. Babkes , Justin Schwab , Christopher S. Mudd , Jason Hoover
发明人： Zachary Dominguez , Mitchell H. Babkes , Justin Schwab , Christopher S. Mudd , Jason Hoover
IPC分类号： A61M29/00 , A61M29/02
CPC分类号： A61F5/0036 , A61F5/0033 , A61F5/0079 , A61F5/0086 , A61F5/0089
摘要： Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.
摘要翻译：描述了跨腹部肥胖症治疗装置及其相关操作方法，其占据胃内的空间和/或刺激胃壁。经腹肥胖治疗装置和相关方法旨在帮助患者保持健康的体重。器件的特征包括经皮插入和无侵入性手术，无相关患者的侵入性手术风险，无明显的患者不适。这些装置的使用寿命可能依赖于酸性胃内的长期生存能力，但意图持续一年或更长时间。这些装置具有在尺寸上变化的能力，并且希望是自动致动，因为它们使用内部电动机或致动器改变形状和/或体积。设备的变化特征有助于防止人的胃部补偿植入物，例如有时会发生静态胃内装置。

6. 发明申请

US20120289769A1 DIRECTIONLESS (ORIENTATION INDEPENDENT) NEEDLE INJECTION PORT 有权
标题翻译：无方向性（独立方向）针头注射口
公开(公告)号：US20120289769A1
公开(公告)日：2012-11-15
申请号：US13104260
申请日：2011-05-10
申请人： Justin Schwab , Sean Snow
发明人： Justin Schwab , Sean Snow
IPC分类号： A61F2/04
CPC分类号： A61F5/0056 , A61F5/0043 , A61M39/0208 , A61M2039/022 , A61M2039/0226 , A61M2039/0238
摘要： Generally described herein are certain embodiments directed to an orientation-independent injection port fluidly coupled to a gastric banding system. The injection port may be configured to simplify the port-targeting process when a medical professional attempts to penetrate the injection port with a needle during a gastric band-adjusting procedure. For example, the injection port may be orientation-independent with the entire outer shell acting as the needle access point. Alternatively, and/or in addition, the inner core of the injection port may be hard or firm, thereby allowing for easier locating (e.g., when the medical professional performs palpation). Furthermore, the hard inner core may prevent needle over-throws, and help stabilize pressure.
摘要翻译：本文通常描述的是针对流体耦合到胃束带系统的取向非依赖性注射端口的某些实施方案。注射端口可以被配置为当医疗专业人员在胃束带调整过程期间试图用针穿透注射端口时，简化端口定位过程。例如，注射口可以是取向独立的，整个外壳用作针入口点。或者，和/或另外，注射口的内芯可以是硬的或坚固的，从而允许更容易的定位（例如当医疗专业人员进行触诊时）。此外，硬内芯可以防止针头过度投掷，并有助于稳定压力。

7. 发明授权

US08956380B2 Reactive intragastric implant devices 有权
标题翻译：反应性胃内植入装置
公开(公告)号：US08956380B2
公开(公告)日：2015-02-17
申请号：US13276182
申请日：2011-10-18
申请人： Zachary Dominguez , Justin Schwab , Mitchell H. Babkes
发明人： Zachary Dominguez , Justin Schwab , Mitchell H. Babkes
IPC分类号： A61M29/00 , A61F5/00
CPC分类号： A61F5/0033 , A61F5/0036
摘要： Transoral three-dimensionally orthogonal intragastric spring systems, devices, methods of operation and manufacture are provided. A transoral three-dimensionally orthogonal intragastric spring system and/or device (and related methods of manufacture and operation) may reduce obesity or weight by stimulating the stomach walls of the patient. The three-dimensionally orthogonal intragastric spring device may be a purely mechanical device comprising a flexible body which in response to an input force in one direction, may deform and cause a resultant displacement in an orthogonal direction, thereby exerting a pressure on the inner stomach walls of the patient. Alternatively, a three-dimensionally orthogonal intragastric spring device may include a variable size balloon configured to occupy volume in the patient's stomach, thereby reducing the amount of space in the patient's stomach.
摘要翻译：提供经口三维正交的胃内弹簧系统，装置，操作和制造方法。经口三维正交的胃内弹簧系统和/或装置（以及相关的制造和手术方法）可以通过刺激患者的胃壁来减轻肥胖或体重。三维正交的胃内弹簧装置可以是纯粹的机械装置，其包括柔性体，该弹性体响应于一个方向上的输入力而变形并引起在正交方向上的合成位移，从而对内壁壁施加压力的病人。或者，三维正交的胃内弹簧装置可以包括构造成占据患者胃中的体积的可变大小的气囊，从而减少患者胃中的空间量。

8. 发明申请

US20120095496A1 REACTIVE INTRAGASTRIC IMPLANT DEVICES 有权
标题翻译：反应性入口植入装置
公开(公告)号：US20120095496A1
公开(公告)日：2012-04-19
申请号：US13276182
申请日：2011-10-18
申请人： Zachary Dominguez , Justin Schwab , Mitchell H. Babkes
发明人： Zachary Dominguez , Justin Schwab , Mitchell H. Babkes
IPC分类号： A61M29/00
CPC分类号： A61F5/0033 , A61F5/0036
摘要： Transoral three-dimensionally orthogonal intragastric spring systems, devices, methods of operation and manufacture are provided. A transoral three-dimensionally orthogonal intragastric spring system and/or device (and related methods of manufacture and operation) may reduce obesity or weight by stimulating the stomach walls of the patient. The three-dimensionally orthogonal intragastric spring device may be a purely mechanical device comprising a flexible body which in response to an input force in one direction, may deform and cause a resultant displacement in an orthogonal direction, thereby exerting a pressure on the inner stomach walls of the patient. Alternatively, a three-dimensionally orthogonal intragastric spring device may include a variable size balloon configured to occupy volume in the patient's stomach, thereby reducing the amount of space in the patient's stomach.
摘要翻译：提供经口三维正交的胃内弹簧系统，装置，操作和制造方法。经口三维正交的胃内弹簧系统和/或装置（以及相关的制造和手术方法）可以通过刺激患者的胃壁来减轻肥胖或体重。三维正交的胃内弹簧装置可以是纯粹的机械装置，其包括柔性体，该弹性体响应于一个方向上的输入力而变形并引起在正交方向上的合成位移，从而对内壁壁施加压力的病人。或者，三维正交的胃内弹簧装置可以包括构造成占据患者胃中的体积的可变大小的气囊，从而减少患者胃中的空间量。

9. 发明申请

US20120095495A1 SPACE-FILLING INTRAGASTRIC IMPLANTS WITH FLUID FLOW 有权
标题翻译：带流体的空间填充入口植入物
公开(公告)号：US20120095495A1
公开(公告)日：2012-04-19
申请号：US13275211
申请日：2011-10-17
申请人： Mitchell H. Babkes , Zachary Dominguez , Justin Schwab
发明人： Mitchell H. Babkes , Zachary Dominguez , Justin Schwab
IPC分类号： A61M29/00
CPC分类号： A61F5/0033 , A61F5/0003 , A61F5/0013 , A61F5/003 , A61F5/0036 , A61F5/0079 , A61F5/0086
摘要： A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive devices do not autonomously change shape, but instead react within the stomach to induce satiety. The devices may take up volume within the stomach, thus reducing the intake capacity. Additionally, the devices may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, to stimulate satiety-inducing nerves. Also, certain devices slow gastric emptying by blocking or otherwise impeding flow through the pyloric sphincter. A number of devices combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the devices within a delivery tube and transorally advancing the devices through the esophagus to be deployed within the stomach. Removal of the devices occurs in the reverse.
摘要翻译：公开了用于肥胖症治疗的各种被动胃内植入装置。这种被动装置不会自主地改变形状，而是在胃内反应以引起饱腹感。这些装置可能占据胃内的体积，从而降低进气能力。此外，装置可以接触胃内的区域，例如围绕食管括约肌的贲门，以刺激饱腹引起的神经。此外，某些装置通过阻塞或阻碍通过幽门括约肌的流动来缓慢胃排空。许多装置组合了这些饱腹感特征中的两种或更多种。公开了植入物的方法，包括压缩输送管内的装置并且经由食道经过胃内部署的装置经过前进。相反的移除设备。

10. 发明授权

US09149383B2 Endolumenal esophageal restriction device 有权
标题翻译：腔内食管限制装置
公开(公告)号：US09149383B2
公开(公告)日：2015-10-06
申请号：US13356401
申请日：2012-01-23
申请人： Justin Schwab , Zachary P. Dominguez , Jason Hoover
发明人： Justin Schwab , Zachary P. Dominguez , Jason Hoover
IPC分类号： A61F5/00
CPC分类号： A61F5/0076 , A61F5/003 , A61F5/005 , A61F5/0079 , A61F2220/0016 , A61F2220/0083
摘要： Generally described herein are apparatus, systems and methods related to a novel esophageal device implantable in the patient's body and designed to replicate the restrictive and satiety mechanism associated with gastric banding systems known in the art. The device can be a compliant and tubular-shaped and fixated within the gastro-esophageal lumen using tissue anchors.
摘要翻译：本文通常描述的是与可植入患者体内的新型食管装置相关的设计，系统和方法，其被设计为复制与本领域已知的胃束带系统相关的限制性和饱腹感机制。该装置可以是柔顺的和管状的并且使用组织锚定件固定在胃食管腔内。

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