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1. 发明授权

US10478615B2 Implantable medical system 有权
公开(公告)号：US10478615B2
公开(公告)日：2019-11-19
申请号：US13128311
申请日：2009-11-04
申请人： Jeroen Jacob Arnold Tol , Ke Wang
发明人： Jeroen Jacob Arnold Tol , Ke Wang
IPC分类号： A61N1/36 , A61N1/05
摘要： This invention relates to an implantable medical system, where an implantable device including a power source operable connected to electrical components is adapted to generate electrical pulses, and a probe having a distal-end and a proximal-end. The distal-end has one or more electrodes adapted to be in electrical contact with a target tissue and wires for connecting the one or more electrodes to the implantable device. The wires conduct the electrical pulses from the implantable device to the one or more electrodes and into the target tissue. The probe has at least one capacitor and wires for connecting the at least one capacitor to the electrical components in the implantable device such that the at least one capacitor forms a part of the electrical components of the implantable device.

2. 发明申请

US20110184495A1 PROBE FOR IMPLANTABLE ELECTRO-STIMULATION DEVICE 有权
标题翻译：可植入电刺激装置的探针
公开(公告)号：US20110184495A1
公开(公告)日：2011-07-28
申请号：US13120758
申请日：2009-10-07
申请人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
发明人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/36
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0531 , A61N1/0551 , A61N1/056 , A61N1/086 , H05K9/002
摘要： The invention relates to a probe for an implantable electro-stimulation device. The probe (20) has a distal end (12) and a proximal end (13), and moreover comprises: one or more electrodes (11) a shield (21) of conducting material covering a major part of the probe, said shield extending from the vicinity of at least one of the one or more electrodes (11) towards the proximal end (13) or towards the distal end (12) of the probe (20); and a layer (22a, 22b) of insulating material covering part of the shield (21) in the vicinity of the at least one of the one or more electrodes. The shield protects wires (14), extending from electrodes to the proximal end of the probe, from undesired interference of external RF fields. The exposed part of the shield not covered by the layer of insulating material serves as a return electrode for the electrostimulation signal path.
摘要翻译：本发明涉及可植入电刺激装置的探针。探针（20）具有远端（12）和近端（13），并且还包括：一个或多个电极（11）覆盖探针的主要部分的导电材料的屏蔽件（21），所述屏蔽件延伸从所述一个或多个电极（11）中的至少一个朝向所述近端（13）或所述探针（20）的远端（12）的附近; 以及覆盖所述一个或多个电极中的至少一个电极附近的所述屏蔽体（21）的一部分的绝缘材料层（22a，22b）。屏蔽保护从电极延伸到探针近端的电线（14）免受外部RF场的不期望的干扰。未被绝缘材料层覆盖的屏蔽件的暴露部分用作电刺激信号路径的返回电极。

3. 发明授权

US09421359B2 Probe for implantable electro-stimulation device 有权
标题翻译：探针用于植入式电刺激装置
公开(公告)号：US09421359B2
公开(公告)日：2016-08-23
申请号：US13120758
申请日：2009-10-07
申请人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
发明人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/05 , H05K9/00 , A61N1/08
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0531 , A61N1/0551 , A61N1/056 , A61N1/086 , H05K9/002
摘要： The invention relates to a probe for an implantable electro-stimulation device. The probe (20) has a distal end (12) and a proximal end (13), and moreover comprises: one or more electrodes (11) a shield (21) of conducting material covering a major part of the probe, said shield extending from the vicinity of at least one of the one or more electrodes (11) towards the proximal end (13) or towards the distal end (12) of the probe (20); and a layer (22a, 22b) of insulating material covering part of the shield (21) in the vicinity of the at least one of the one or more electrodes. The shield protects wires (14), extending from electrodes to the proximal end of the probe, from undesired interference of external RF fields. The exposed part of the shield not covered by the layer of insulating material serves as a return electrode for the electrostimulation signal path.
摘要翻译：本发明涉及可植入电刺激装置的探针。探针（20）具有远端（12）和近端（13），并且还包括：一个或多个电极（11）覆盖探针的主要部分的导电材料的屏蔽件（21），所述屏蔽件延伸从所述一个或多个电极（11）中的至少一个朝向所述近端（13）或所述探针（20）的远端（12）的附近; 以及覆盖所述一个或多个电极中的至少一个电极附近的所述屏蔽体（21）的一部分的绝缘材料层（22a，22b）。屏蔽保护从电极延伸到探针近端的电线（14）免受外部RF场的不期望的干扰。未被绝缘材料层覆盖的屏蔽件的暴露部分用作电刺激信号路径的返回电极。

4. 发明授权

US08688230B2 System comprising a box for implanting in a body part 有权
标题翻译：系统包括用于植入身体部位的盒子
公开(公告)号：US08688230B2
公开(公告)日：2014-04-01
申请号：US13265408
申请日：2010-04-21
申请人： Michel Gerardus Pardoel , Michel Marcel Jose Decre , Hubert Cécile François Martens , Franciscus Paulus Maria Budzelaar , Jozef Elisabeth Franciscus Gootzen , Jeroen Jacob Arnold Tol
发明人： Michel Gerardus Pardoel , Michel Marcel Jose Decre , Hubert Cécile François Martens , Franciscus Paulus Maria Budzelaar , Jozef Elisabeth Franciscus Gootzen , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/08
CPC分类号： A61N1/375 , A61N1/0529 , A61N1/0539 , A61N1/37229
摘要： A system (102) comprising a box (104) for implanting in a mammal body part (106), which box is provided with a first electrical contact (110, 121, 114, 116, 118, 120), and a module (108) for accommodating in the box, which module is provided with a second electrical contact (122, 124, 126) for cooperation with said first electrical contact. The first electrical contact and the second electrical contact are mutually movable, at least in a stationary accommodation of the module in the box, between a contact position in which said first and second electrical contacts are electrically connected, and a non-contact position in which said first and second electrical contacts are separated from each other.
摘要翻译：一种系统（102），包括用于植入哺乳动物体部分（106）中的盒（104），所述盒设置有第一电触头（110,121,114,116,118,120）和模块（108 ），用于容纳在盒中，该模块设置有用于与所述第一电触点配合的第二电触点（122,124,126）。所述第一电触点和所述第二电接触件至少在所述模块在所述模块的静态容纳部中，在所述第一和第二电触点电连接的触点位置和非接触位置之间，所述第一和第二电触点彼此分离。

5. 发明授权

US08390416B2 Reuse of screw thread 有权
标题翻译：螺纹重复使用
公开(公告)号：US08390416B2
公开(公告)日：2013-03-05
申请号：US13125091
申请日：2009-10-21
申请人： Jacobus Josephus Leijssen , Jeroen Jacob Arnold Tol
发明人： Jacobus Josephus Leijssen , Jeroen Jacob Arnold Tol
IPC分类号： H01F27/28 , H01F27/02 , A61N1/00
CPC分类号： H01F5/00 , A61N1/37229 , A61N1/3787 , H01F38/14 , H01Q1/22 , H01Q7/00
摘要： Components having a screw thread useful for mechanical fixation of the component to a corresponding component may be equipped with electrical wire following at least part of the turns of the screw thread and thereby forming at least a part of a coil. The corresponding component may have a matching screw thread, or the component of the invention may be self-tapping, in which case a matching screw thread in the corresponding component would be superfluous. The coil may be used as charging and/or power-conversion coil and/or communication antenna. The reuse of the screw thread for a coil maximizes the coil area without consuming extra space of the component. This is in particular useful in medical electrical implant devices, such as a pace maker or a neuron pace maker in deep brain stimulation, in that the maximum size of such a pace maker is very limited. Moreover, the screw thread of such components may additionally comprise connectors for providing electrical connection to other electrical parts in a matching component.
摘要翻译：具有用于将部件机械固定到相应部件的螺纹的部件可以配备有沿着螺纹的至少一部分匝的电线，从而形成线圈的至少一部分。相应的部件可以具有匹配的螺纹，或者本发明的部件可以是自攻丝的，在这种情况下，相应部件中的匹配螺纹将是多余的。线圈可以用作充电和/或功率转换线圈和/或通信天线。用于线圈的螺纹的再利用使线圈面积最大化，而不消耗部件的额外空间。这在医疗电植入装置中尤其有用，例如在深部脑刺激中的起搏器或神经元起搏器，因为这种起搏器的最大尺寸非常有限。此外，这些部件的螺纹还可以包括用于提供与匹配部件中的其它电气部件的电连接的连接器。

6. 发明申请

US20110184492A1 SYSTEM AND METHOD FOR COMMUNICATING INFORMATION BETWEEN IMPLANTABLE DEVICES 有权
标题翻译：用于在可移植设备之间传递信息的系统和方法
公开(公告)号：US20110184492A1
公开(公告)日：2011-07-28
申请号：US13054857
申请日：2009-07-22
申请人： Hubert Cécile François Martens , Franciscus Paulus Maria Budzelaar , Jeroen Jacob Arnold Tol
发明人： Hubert Cécile François Martens , Franciscus Paulus Maria Budzelaar , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/36
CPC分类号： A61N1/37288 , A61N1/362 , A61N1/37252
摘要： A system for communicating information between at least two medical devices implanted within the body of a subject using volume conduction of electrical signals as a means of communication and wherein one of the implanted medical devices is configured to provide electrical stimulation to the tissue is disclosed. The system comprises a first implant device having at least two transmit electrodes configured to transmit electrical stimulation pulses, wherein one of the electrodes may be a common return electrode, an encoding means configured to employ a channel as a transmitter transmission medium for stimulation pulses and encoding the information into the stimulation pulses, a second implant device having at least two receive electrodes configured to receive the transmitted stimulation pulses with encoded information, and a decoding means configured to decode the information encoded into the stimulation pulses. The disclosed system provides reliable and efficient communication between implantable receiver devices.
摘要翻译：公开了一种系统，用于在作为通信手段的电信号的体积传导之间在植入物体内的至少两个医疗设备之间传送信息，并且其中植入的医疗设备中的一个被配置为向组织提供电刺激。所述系统包括具有至少两个发射电极的第一注入装置，所述至少两个发射电极被配置为传输电刺激脉冲，其中所述电极中的一个可以是公共返回电极，编码装置被配置为使用通道作为用于刺激脉冲的发射器传输介质和编码将信息输入到刺激脉冲中，具有至少两个接收电极的第二植入装置，所述接收电极被配置为用编码信息接收所发送的刺激脉冲;以及解码装置，被配置为对编码为刺激脉冲的信息进行解码。所公开的系统在可植入接收器设备之间提供可靠和有效的通信。

7. 发明申请

US20130009691A1 Control Circuitry And Method For Controlling A Bi-Directional Switch System, A Bi-Directional Switch, A Switching Matrix And A Medical Stimulator 有权
标题翻译：用于控制双向开关系统的控制电路和方法，双向开关，开关矩阵和医疗刺激器
公开(公告)号：US20130009691A1
公开(公告)日：2013-01-10
申请号：US13636137
申请日：2011-04-05
申请人： Pieter Gerrit Blanken , Jeroen Jacob Arnold Tol , Franciscus Adrianus Cornelis Maria Schoofs , Dave Willem Van Goor
发明人： Pieter Gerrit Blanken , Jeroen Jacob Arnold Tol , Franciscus Adrianus Cornelis Maria Schoofs , Dave Willem Van Goor
IPC分类号： H03K17/66
CPC分类号： H02J7/008 , A61N1/05 , A61N1/36185 , H02J7/0052 , H02J7/345 , H03K17/063 , H03K17/687
摘要： A control circuitry (134) and a method for controlling a bi-directional switch (132) is provided. The bi-directional switch (132) having a control terminal (130) for receiving a control voltage (124) to control an on state and an off state of the bi-directional switch (132) and at least one semiconductor switch in a bi-directional main current path. The control circuitry (134) comprises an energy storage element (102), a coupling means (101) to couple the energy storage element (102) to a supply voltage to charge the energy storage element (102), and a control circuit (108) configured to receive power from the energy storage element (102) and configured to supply the control voltage having a voltage level being independent of the supply voltage when the energy storage element (102) is not coupled to the supply voltage. The coupling means (101) is configured for only coupling the 132 energy storage element (102) to the supply voltage when the bi-directional switch (132) is in the off state.
摘要翻译：提供了控制电路（134）和用于控制双向开关（132）的方法。双向开关（132）具有用于接收控制电压（124）以控制双向开关（132）的导通状态和断开状态的控制端子（130）和双向开关（132）中的至少一个半导体开关双向主电流路径。控制电路（134）包括能量存储元件（102），将能量存储元件（102）耦合到电源电压以对能量存储元件（102）充电的耦合装置（101）和控制电路（108）），其被配置为从所述能量存储元件（102）接收电力，并且被配置为当所述能量存储元件（102）未耦合到所述电源电压时，提供具有与所述电源电压无关的电压电平的所述控制电压。耦合装置（101）被配置为当双向开关（132）处于关闭状态时，仅将132能量存储元件（102）耦合到电源电压。

8. 发明申请

US20120065458A1 IMPLANTABLE DEVICE WITH COMMUNICATION MEANS 审中-公开
标题翻译：具有通信手段的可植入设备
公开(公告)号：US20120065458A1
公开(公告)日：2012-03-15
申请号：US13320614
申请日：2010-05-04
申请人： Jeroen Jacob Arnold Tol
发明人： Jeroen Jacob Arnold Tol
IPC分类号： H04R25/00
CPC分类号： A61N1/37217 , A61N1/36082 , A61N1/372
摘要： The invention relates to an implantable device, e.g. a Deep Brain Stimulation device (10), and to a method for communicating information from such an implantable device (10) to its carrier. The communication is achieved by the emission of sound from a transmitter (16) into the body material surrounding the implantable device (10), wherein said sound yields signals that are audible for the carrier of the implantable device (10). In particular, the emitted sound may comprise audible frequencies or modulated ultrasonic frequencies. According to a further development, the implantable device (10) may additionally comprise a receiver (16) for receiving sound from the surrounding body material, wherein said received sound may encode information for the implantable device (10).
摘要翻译：本发明涉及可植入装置，例如，深脑刺激装置（10），以及用于将信息从这种可植入装置（10）传送到其载体的方法。通信是通过从发射机（16）发射声音到围绕可植入装置（10）的主体材料中实现的，其中所述声音产生对可植入装置（10）的载体是可听见的信号。特别地，发射的声音可以包括可听频率或调制的超声波频率。根据进一步的发展，可植入装置（10）可另外包括用于从周围主体材料接收声音的接收器（16），其中所述接收的声音可以编码可植入装置（10）的信息。

9. 发明申请

US20120120684A1 APPARATUS WITH INTERNAL POWER TRANSFER 有权
标题翻译：具有内部电力传输的装置
公开(公告)号：US20120120684A1
公开(公告)日：2012-05-17
申请号：US13383601
申请日：2010-06-30
申请人： Jeroen Jacob Arnold Tol , Franciscus Paulus Maria Budzelaar
发明人： Jeroen Jacob Arnold Tol , Franciscus Paulus Maria Budzelaar
IPC分类号： H02M3/335
CPC分类号： A61N1/378 , A61N1/08 , H02J7/0065 , H02J2001/002 , H02M7/48
摘要： The invention relates to an electronic apparatus (I) with a DC power source (B) and power-consuming electronic circuits (EC) and to a method of transferring power between these components. The DC voltage of the power source (B) is converted into an AC voltage which is then transferred via a connector (C) to the electronic circuits (EC). Negative effects due to a contamination of the connector (C) with moisture from the environment can hence be minimized The invention is particularly suited for implantable devices as it allows to couple a replaceable battery (B) with electronic circuits (EC) via a non-sealed connector (C).
摘要翻译：本发明涉及一种具有直流电源（B）和耗电量电子电路（EC）的电子设备（I）以及一种在这些组件之间传送电能的方法。电源（B）的直流电压被转换为交流电压，然后经由连接器（C）传送到电子电路（EC）。因此，由于连接器（C）与来自环境的水分的污染导致的负面影响因此可以最小化本发明特别适用于可植入装置，因为它允许通过非易失性存储器将可更换电池（E）与电子电路（EC）密封连接器（C）。

10. 发明申请

US20110199173A1 REUSE OF SCREW THREAD 有权
标题翻译：螺丝螺纹的重新使用
公开(公告)号：US20110199173A1
公开(公告)日：2011-08-18
申请号：US13125091
申请日：2009-10-21
申请人： Jacobus Josephus Leijssen , Jeroen Jacob Arnold Tol
发明人： Jacobus Josephus Leijssen , Jeroen Jacob Arnold Tol
IPC分类号： H01F27/06
CPC分类号： H01F5/00 , A61N1/37229 , A61N1/3787 , H01F38/14 , H01Q1/22 , H01Q7/00
摘要： Components having a screw thread useful for mechanical fixation of the component to a corresponding component may be equipped with electrical wire following at least part of the turns of the screw thread and thereby forming at least a part of a coil. The corresponding component may have a matching screw thread, or the component of the invention may be self-tapping, in which case a matching screw thread in the corresponding component would be superfluous. The coil may be used as charging and/or power-conversion coil and/or communication antenna. The reuse of the screw thread for a coil maximizes the coil area without consuming extra space of the component. This is in particular useful in medical electrical implant devices, such as a pace maker or a neuron pace maker in deep brain stimulation, in that the maximum size of such a pace maker is very limited. Moreover, the screw thread of such components may additionally comprise connectors for providing electrical connection to other electrical parts in a matching component.
摘要翻译：具有用于将部件机械固定到相应部件的螺纹的部件可以配备有沿着螺纹的至少一部分匝的电线，从而形成线圈的至少一部分。相应的部件可以具有匹配的螺纹，或者本发明的部件可以是自攻丝的，在这种情况下，相应部件中的匹配螺纹将是多余的。线圈可以用作充电和/或功率转换线圈和/或通信天线。用于线圈的螺纹的再利用使线圈面积最大化，而不消耗部件的额外空间。这在医疗电植入装置中尤其有用，例如在深部脑刺激中的起搏器或神经元起搏器，因为这种起搏器的最大尺寸非常有限。此外，这些部件的螺纹还可以包括用于提供与匹配部件中的其它电气部件的电连接的连接器。

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