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1. 发明申请

US20060257285A1 Colormetric imaging array device 审中-公开
标题翻译：成像阵列设备
公开(公告)号：US20060257285A1
公开(公告)日：2006-11-16
申请号：US10966755
申请日：2004-10-14
申请人： Jeremy Burdon , Manuel Oliver , Peter Roberts
发明人： Jeremy Burdon , Manuel Oliver , Peter Roberts
IPC分类号： G01N31/22 , G01N21/00
CPC分类号： G01N31/22 , G01N21/78
摘要： An apparatus is provided for detecting an atmospheric component. The apparatus comprises one or more arrays, wherein each array comprises one or more colorimetric reagents. A material encapsulating the colorimetric reagents of each array is capable of being at least partially removed to expose the colorimetric reagents of a selected array to the atmosphere. An imager detects colors of the one or more colorimetric reagents in the selected array. Circuitry then determines changes in colors of the one or more colorimetric reagents within the selected array.
摘要翻译：提供了一种用于检测大气成分的装置。该装置包括一个或多个阵列，其中每个阵列包含一种或多种比色试剂。包封每个阵列的比色试剂的材料能够被至少部分去除以将选定阵列的比色试剂暴露于大气中。成像仪检测所选阵列中的一种或多种比色试剂的颜色。然后电路确定所选阵列内的一种或多种比色试剂的颜色变化。

2. 发明申请

US20070060970A1 Miniaturized co-fired electrical interconnects for implantable medical devices 审中-公开
标题翻译：用于可植入医疗器械的小型化共烧电互连
公开(公告)号：US20070060970A1
公开(公告)日：2007-03-15
申请号：US11227375
申请日：2005-09-15
申请人： Jeremy Burdon , Joyce Yamamoto
发明人： Jeremy Burdon , Joyce Yamamoto
IPC分类号： A61N1/00
CPC分类号： A61N1/3754 , H01L23/10 , H01L2924/0002 , H01L2924/01079 , H01L2924/09701 , H01L2924/15192 , H01L2924/16152 , H01L2924/16251 , H01L2924/3011 , H05K1/0306 , H05K1/115 , H05K3/4611 , H05K3/4629 , H05K2201/09627 , H05K2201/09709 , H01L2924/00
摘要： The invention includes a family of miniaturized, hermetic electrical feedthrough assemblies adapted for implantation within a biological system. An electrical feedthrough assembly according to the invention can be used as a component of an implantable medical device (IMD) such as an implantable pulse generator, cardioverter-defibrillator, physiologic sensor, drug-delivery system and the like. Such assemblies require biocompatibility and resistance to degradation under applied bias current or voltage. Such an assembly is fabricated by interconnected electrical pathways, or vias, of a conductive metallic paste disposed between ceramic green-state material. The layers are stacked together and sintered to form a substantially monolithic dielectric structure with at least one embedded metallization pathway extending through the structure. The metallization pathway reliably conducts electrical signals even when exposed to body fluids and tissue and providing electrical communication between internal IMD circuitry and active electrical components and/or circuitry coupled to the exterior of an IMD.
摘要翻译：本发明包括一系列适于植入生物系统的小型化，密封电气馈通组件。根据本发明的电馈通组件可以用作可植入医疗装置（IMD）的组件，例如可植入脉冲发生器，心律转复除颤器，生理传感器，药物递送系统等。这样的组件需要在施加的偏置电流或电压下的生物相容性和耐劣化性。这种组件由布置在陶瓷绿色材料之间的导电金属膏的互连电路或通路制成。层叠在一起并烧结以形成具有延伸穿过该结构的至少一个嵌入金属化路径的基本上单片的电介质结构。金属化路径即使暴露于体液和组织也可靠地传导电信号，并提供内部IMD电路与耦合到IMD外部的有源电气部件和/或电路之间的电气通信。

3. 发明申请

US20060247539A1 Implantable capacitive pressure sensor system and method 有权
标题翻译：可植入电容式压力传感器系统及方法
公开(公告)号：US20060247539A1
公开(公告)日：2006-11-02
申请号：US11116804
申请日：2005-04-28
申请人： Michael Schugt , Keith Miesel , Jeremy Burdon , Eric Bonde
发明人： Michael Schugt , Keith Miesel , Jeremy Burdon , Eric Bonde
IPC分类号： A61B5/02
CPC分类号： A61B5/0215 , H01L2224/48227 , H01L2924/15192
摘要： Embodiments of the invention provide systems and methods for an implantable capacitive pressure sensor. Some embodiments of the invention include a capacitive pressure sensor capsule comprising a substrate, a conductive plate functionally coupled to the substrate, a conductive diaphragm spaced from the conductive plate and functionally coupled to the substrate, a lid hermetically sealed against the substrate, and pressure sensing circuitry disposed within a volume generally defined by the lid and the substrate. Embodiments of the invention also include a lead provided with an implantable pressure sensor capsule and a method of manufacturing a capacitive pressure sensor capsule.
摘要翻译：本发明的实施例提供了一种用于可植入电容式压力传感器的系统和方法。本发明的一些实施例包括电容式压力传感器胶囊，其包括基底，功能性地连接到基底的导电板，与导电板隔开并功能耦合到基底的导电隔膜，密封地密封在基底上的盖，以及压力感测设置在通常由盖和基板限定的体积内的电路。本发明的实施例还包括具有可植入压力传感器胶囊的引线和制造电容式压力传感器胶囊的方法。

4. 发明申请

US20070236861A1 IMPLANTABLE CO-FIRED ELECTRICAL FEEDTHROUGHS 审中-公开
标题翻译：可植入式电动发电机
公开(公告)号：US20070236861A1
公开(公告)日：2007-10-11
申请号：US11278773
申请日：2006-04-05
申请人： Jeremy Burdon , Joyce Yamamoto , Lea Nygren , William Wolf
发明人： Jeremy Burdon , Joyce Yamamoto , Lea Nygren , William Wolf
IPC分类号： H01G4/35
CPC分类号： A61N1/3754
摘要： A hermetic interconnect for implantable medical devices is presented. In one embodiment, the hermetic interconnect includes a conductive material introduced to a via in a single layer. The conductive material includes a first end and a second end. A first bonding pad is coupled to the first end of the conductive material. A second bonding pad is coupled to the second end of the conductive material. The single layer and the conductive material undergo a co-firing process.
摘要翻译：介绍了可植入医疗器械的气密互连。在一个实施例中，气密互连包括在单层中引入通孔的导电材料。导电材料包括第一端和第二端。第一焊盘耦合到导电材料的第一端。第二接合焊盘耦合到导电材料的第二端。单层和导电材料经历共烧制过程。

5. 发明申请

US20070060969A1 Implantable co-fired electrical feedthroughs 审中-公开
标题翻译：可植入联合电气馈通
公开(公告)号：US20070060969A1
公开(公告)日：2007-03-15
申请号：US11227342
申请日：2005-09-15
申请人： Jeremy Burdon , Joyce Yamamoto , Lea Nygren , William Wolf
发明人： Jeremy Burdon , Joyce Yamamoto , Lea Nygren , William Wolf
IPC分类号： A61N1/375
CPC分类号： A61N1/3754 , A61N1/375 , H01G9/10
摘要： The invention includes a family of miniaturized, hermetic electrical feedthrough assemblies adapted for implantation within a biological system. An electrical feedthrough assembly according to the invention can be used as a component of an implantable medical device such as an implantable pulse generator, cardioverter-defibrillator, physiologic sensor, drug-delivery system and the like. Such assemblies require biocompatibility and resistance to degradation under applied bias current or voltage. Such an assembly is fabricated by interconnected electrical pathways, or vias, of a conductive metallic paste disposed between ceramic green-state material. The layers are stacked together and sintered to form a substantially monolithic dielectric structure with at least one embedded metallization pathway extending through the structure. The metallization pathway reliably conducts electrical signals even when exposed to body fluids and tissue and providing reliable electrical communication. After sintering the structure is hermetically diffusion bonded to a part of a ferrule and/or adjacent support member.
摘要翻译：本发明包括一系列适于植入生物系统的小型化，密封电气馈通组件。根据本发明的电馈通组件可以用作可植入医疗装置的组件，例如可植入脉冲发生器，心律转复除颤器，生理传感器，药物递送系统等。这样的组件需要在施加的偏置电流或电压下的生物相容性和耐劣化性。这种组件由布置在陶瓷绿色材料之间的导电金属膏的互连电路或通路制成。层叠在一起并烧结以形成具有延伸穿过该结构的至少一个嵌入金属化路径的基本上单片的电介质结构。即使暴露于体液和组织并且提供可靠的电通信，金属化路径也可靠地传导电信号。在烧结之后，结构气密地扩散粘合到套圈和/或相邻的支撑构件的一部分上。

6. 发明授权

US06605454B2 Microfluidic devices with monolithic microwave integrated circuits 有权
公开(公告)号：US06605454B2
公开(公告)日：2003-08-12
申请号：US09816512
申请日：2001-03-22
申请人： Barbara Foley Barenburg , Jeremy Burdon , Yuk-Tong Chan , Xunhu Dai , Sean Gallagher , Piotr Grodzinski , Robert Marrero , Vijay Nair , David Rhine , Thomas Smekal
发明人： Barbara Foley Barenburg , Jeremy Burdon , Yuk-Tong Chan , Xunhu Dai , Sean Gallagher , Piotr Grodzinski , Robert Marrero , Vijay Nair , David Rhine , Thomas Smekal
IPC分类号： C12N1300
CPC分类号： H05B6/806 , C12N1/066 , C12N13/00
摘要： A microwave device has a monolithic microwave integrated circuit (MMIC) disposed therein for applying microwave radiation to a microfluidic structure, such as a chamber, defined in the device. The microwave radiation from the MMIC is useful for heating samples introduced into the microfluidic structure and for effecting lysis of cells in the samples. Microfabrication techniques allow the fabrication of MMICs that perform heating and cell lysing of samples having volumes in the microliter to picoliter range.

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