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    • 1. 发明申请
    • PNA Probes, Probe Sets, Methods and Kits Pertaining to the Detection of Candida
    • PNA探针,探针组,与假丝酵母检测有关的方法和试剂盒
    • US20120082980A1
    • 2012-04-05
    • US13207283
    • 2011-08-10
    • Jens J. HYLDIG-NIELSENHenrik StenderKenneth M. OliveiraSusan Rigby
    • Jens J. HYLDIG-NIELSENHenrik StenderKenneth M. OliveiraSusan Rigby
    • C12Q1/68
    • C12Q1/6895C07K14/003C12Q1/689C12Q2525/107
    • This invention is related to novel PNA probes, probe sets, methods and kits pertaining to the detection of one or more species of Candida yeast. Non-limiting examples of probing nucleobase sequences that can be used for the probes of this invention can be selected from the group consisting of: AGA-GAG-CAG-CAT-GCA (Seq. Id. No. 1), AGA-GAG-CAA-CAT-GCA (Seq. Id. No. 2), ACA-GCA-GAA-GCC-GTG (Seq. Id. No. 3), CAT-AAA-TGG-CTA-CCA-GA (Seq. Id. No. 4), CAT-AAA-TGG-CTA-CCC-AG (Seq. Id. No. 5), ACT-TGG-AGT-CGA-TAG (Seq. Id. No. 6), CCA-AGG-CTT-ATA-CTC-GC (Seq. Id. No. 7), CCC-CTG-AAT-CGG-GAT (Seq. Id. No. 8), GAC-GCC-AAA-GAC-GCC (Seq. Id. No. 9), ATC-GTC-AGA-GGC-TAT-AA (Seq. Id. No. 10), TAG-CCA-GAA-GAA-AGG (Seq. Id. No. 11), CAT-AAA-TGG-CTA-GCC-AG (Seq. Id. No. 12), CTC-CGA-TGT-GAC-TGC-G (Seq. Id. No. 13), TCC-CAG-ACT-GCT-CGG (Seq. Id. No. 14), TCC-AAG-AGG-TCG-AGA (Seq. Id. No. 15), GCC-AAG-CCA-CAA-GGA (Seq. Id. No. 16), GCC-GCC-AAG-CCA-CA (Seq. Id. No. 17), GGA-CTT-GGG-GTT-AG (Seq. Id. No. 18), CCG-GGT-GCA-TTC-CA (Seq. Id. No. 19), ATG-TAG-AAC-GGA-ACT-A (Seq. Id. No. 20), GAT-TCT-CGG-CCC-CAT-G (Seq. Id. No. 21), CTG-GTT-CGC-CAA-AAA-G (Seq. Id. No. 22) and AGT-ACG-CAT-CAG-AAA (Seq. Id. No. 23).
    • 本发明涉及与一种或多种念珠菌酵母的检测有关的新型PNA探针,探针组,方法和试剂盒。 可用于本发明探针的探测核碱基序列的非限制性实例可以选自:AGA-GAG-CAG-CAT-GCA(Seq.Id。No.1),AGA-GAG- CAA-CAT-GCA(序列号2),ACA-GCA-GAA-GCC-GTG(序列号3),CAT-AAA-TGG-CTA-CCA-GA(Seq.Id。 第4号),CAT-AAA-TGG-CTA-CCC-AG(Seq.Id。No.5),ACT-TGG-AGT-CGA-TAG(Seq.Id。No.6),CCA-AGG-CTT -ATA-CTC-GC(Seq.Id。No.7),CCC-CTG-AAT-CGG-GAT(Seq.Id。No.8),GAC-GCC-AAA-GAC-GCC(Seq.Id.No ATC-GTC-AGA-GGC-TAT-AA(序列号10),TAG-CCA-GAA-GAA-AGG(序列号11),CAT-AAA-TGG- CTA-GCC-AG(序列号12),CTC-CGA-TGT-GAC-TGC-G(序列号13),TCC-CAG-ACT-GCT-CGG(Seq.Id。 第14号),TCC-AAG-AGG-TCG-AGA(序列号15),GCC-AAG-CCA-CAA-GGA(序列号16),GCC-GCC-AAG-CCA -CA(Seq.Id。No.17),GGA-CTT-GGG-GTT-AG(Seq.Id.18),CCG-GGT-GCA-TTC-CA(Seq.Id.No.19) ATG-TAG-AAC-GGA-ACT-A(序列号20),GAT-TCT-CGG-CCC-CAT-G(序列号21),CTG-GTT-CGC-CAA- AAA-G (Seq。 ID。 No.22)和AGT-ACG-CAT-CAG-AAA(Seq.Id。No.23)。
    • 2. 发明授权
    • PNA probes, probe sets, methods and kits pertaining to the detection of Candida
    • PNA探针,探针组,与念珠菌检测有关的方法和试剂盒
    • US08912312B2
    • 2014-12-16
    • US13207283
    • 2011-08-10
    • Jens J. Hyldig-NielsenHenrik StenderKenneth M. OliveiraSusan Rigby
    • Jens J. Hyldig-NielsenHenrik StenderKenneth M. OliveiraSusan Rigby
    • C12Q1/68C07K14/00
    • C12Q1/6895C07K14/003C12Q1/689C12Q2525/107
    • This invention is related to novel PNA probes, probe sets, methods and kits pertaining to the detection of one or more species of Candida yeast. Non-limiting examples of probing nucleobase sequences that can be used for the probes of this invention can be selected from the group consisting of: AGA-GAG-CAG-CAT-GCA (Seq. Id. No. 1), AGA-GAG-CAA-CAT-GCA (Seq. Id. No. 2), ACA-GCA-GAA-GCC-GTG (Seq. Id. No. 3), CAT-AAA-TGG-CTA-CCA-GA (Seq. Id. No. 4), CAT-AAA-TGG-CTA-CCC-AG (Seq. Id. No. 5), ACT-TGG-AGT-CGA-TAG (Seq. Id. No. 6), CCA-AGG-CTT-ATA-CTC-GC (Seq. Id. No. 7), CCC-CTG-AAT-CGG-GAT (Seq. Id. No. 8), GAC-GCC-AAA-GAC-GCC (Seq. Id. No. 9), ATC-GTC-AGA-GGC-TAT-AA (Seq. Id. No. 10), TAG-CCA-GAA-GAA-AGG (Seq. Id. No. 11), CAT-AAA-TGG-CTA-GCC-AG (Seq. Id. No. 12), CTC-CGA-TGT-GAC-TGC-G (Seq. Id. No. 13), TCC-CAG-ACT-GCT-CGG (Seq. Id. No. 14), TCC-AAG-AGG-TCG-AGA (Seq. Id. No. 15), GCC-AAG-CCA-CAA-GGA (Seq. Id. No. 16), GCC-GCC-AAG-CCA-CA (Seq. Id. No. 17), GGA-CTT-GGG-GTT-AG (Seq. Id. No. 18), CCG-GGT-GCA-TTC-CA (Seq. Id. No. 19), ATG-TAG-AAC-GGA-ACT-A (Seq. Id. No. 20), GAT-TCT-CGG-CCC-CAT-G (Seq. Id. No. 21), CTG-GTT-CGC-CAA-AAA-G (Seq. Id. No. 22) and AGT-ACG-CAT-CAG-AAA (Seq. Id. No. 23).
    • 本发明涉及与一种或多种念珠菌酵母的检测有关的新型PNA探针,探针组,方法和试剂盒。 可用于本发明探针的探测核碱基序列的非限制性实例可以选自:AGA-GAG-CAG-CAT-GCA(Seq.Id。No.1),AGA-GAG- CAA-CAT-GCA(序列号2),ACA-GCA-GAA-GCC-GTG(序列号3),CAT-AAA-TGG-CTA-CCA-GA(Seq.Id。 第4号),CAT-AAA-TGG-CTA-CCC-AG(Seq.Id。No.5),ACT-TGG-AGT-CGA-TAG(Seq.Id。No.6),CCA-AGG-CTT -ATA-CTC-GC(Seq.Id。No.7),CCC-CTG-AAT-CGG-GAT(Seq.Id。No.8),GAC-GCC-AAA-GAC-GCC(Seq.Id.No ATC-GTC-AGA-GGC-TAT-AA(序列号10),TAG-CCA-GAA-GAA-AGG(序列号11),CAT-AAA-TGG- CTA-GCC-AG(序列号12),CTC-CGA-TGT-GAC-TGC-G(序列号13),TCC-CAG-ACT-GCT-CGG(Seq.Id。 第14号),TCC-AAG-AGG-TCG-AGA(序列号15),GCC-AAG-CCA-CAA-GGA(序列号16),GCC-GCC-AAG-CCA -CA(Seq.Id。No.17),GGA-CTT-GGG-GTT-AG(Seq.Id.18),CCG-GGT-GCA-TTC-CA(Seq.Id.No.19) ATG-TAG-AAC-GGA-ACT-A(序列号20),GAT-TCT-CGG-CCC-CAT-G(序列号21),CTG-GTT-CGC-CAA- AAA-G (Seq。 ID。 No.22)和AGT-ACG-CAT-CAG-AAA(Seq.Id。No.23)。
    • 3. 发明授权
    • PNA probes, probe sets, methods and kits pertaining to the detection of Candida
    • PNA探针,探针组,与念珠菌检测有关的方法和试剂盒
    • US08026051B2
    • 2011-09-27
    • US10150045
    • 2002-05-17
    • Jens J. Hyldig-NielsenHenrik StenderKenneth M. OliveiraSusan Rigby
    • Jens J. Hyldig-NielsenHenrik StenderKenneth M. OliveiraSusan Rigby
    • C07H21/04C12Q1/68
    • C12Q1/6895C07K14/003C12Q1/689C12Q2525/107
    • This invention is related to novel PNA probes, probe sets, methods and kits pertaining to the detection of one or more species of Candida yeast. Non-limiting examples of probing nucleobase sequences that can be used for the probes of this invention can be selected from the group consisting of: AGA-GAG-CAG-CAT-GCA (Seq. Id. No. 1), AGA-GAG-CAA-CAT-GCA (Seq. Id. No. 2), ACA-GCA-GAA-GCC-GTG (Seq. Id. No. 3), CAT-AAA-TGG-CTA-CCA-GA (Seq. Id. No. 4), CAT-AAA-TGG-CTA-CCC-AG (Seq. Id. No. 5), ACT-TGG-AGT-CGA-TAG (Seq. Id. No. 6), CCA-AGG-CTT-ATA-CTC-GC (Seq. Id. No. 7), CCC-CTG-AAT-CGG-GAT (Seq. Id. No. 8), GAC-GCC-AAA-GAC-GCC (Seq. Id. No. 9), ATC-GTC-AGA-GGC-TAT-AA (Seq. Id. No. 10), TAG-CCA-GAA-GAA-AGG (Seq. Id. No. 11), CAT-AAA-TGG-CTA-GCC-AG (Seq. Id. No. 12), CTC-CGA-TGT-GAC-TGC-G (Seq. Id. No. 13), TCC-CAG-ACT-GCT-CGG (Seq. Id. No. 14), TCC-AAG-AGG-TCG-AGA (Seq. Id. No. 15), GCC-AAG-CCA-CAA-GGA (Seq. Id. No. 16), GCC-GCC-AAG-CCA-CA (Seq. Id. No. 17), GGA-CTT-GGG-GTT-AG (Seq. Id. No. 18), CCG-GGT-GCA-TTC-CA (Seq. Id. No. 19), ATG-TAG-AAC-GGA-ACT-A (Seq. Id. No. 20), GAT-TCT-CGG-CCC-CAT-G (Seq. Id. No. 21), CTG-GTT-CGC-CAA-AAA-G (Seq. Id. No. 22) and AGT-ACG-CAT-CAG-AAA (Seq. Id. No. 23).
    • 本发明涉及与一种或多种念珠菌酵母的检测有关的新型PNA探针,探针组,方法和试剂盒。 可用于本发明探针的探测核碱基序列的非限制性实例可以选自:AGA-GAG-CAG-CAT-GCA(Seq.Id。No.1),AGA-GAG- CAA-CAT-GCA(序列号2),ACA-GCA-GAA-GCC-GTG(序列号3),CAT-AAA-TGG-CTA-CCA-GA(Seq.Id。 第4号),CAT-AAA-TGG-CTA-CCC-AG(Seq.Id。No.5),ACT-TGG-AGT-CGA-TAG(Seq.Id。No.6),CCA-AGG-CTT -ATA-CTC-GC(Seq.Id。No.7),CCC-CTG-AAT-CGG-GAT(Seq.Id。No.8),GAC-GCC-AAA-GAC-GCC(Seq.Id.No ATC-GTC-AGA-GGC-TAT-AA(序列号10),TAG-CCA-GAA-GAA-AGG(序列号11),CAT-AAA-TGG- CTA-GCC-AG(序列号12),CTC-CGA-TGT-GAC-TGC-G(序列号13),TCC-CAG-ACT-GCT-CGG(Seq.Id。 第14号),TCC-AAG-AGG-TCG-AGA(序列号15),GCC-AAG-CCA-CAA-GGA(序列号16),GCC-GCC-AAG-CCA -CA(Seq.Id。No.17),GGA-CTT-GGG-GTT-AG(Seq.Id.18),CCG-GGT-GCA-TTC-CA(Seq.Id.No.19) ATG-TAG-AAC-GGA-ACT-A(序列号20),GAT-TCT-CGG-CCC-CAT-G(序列号21),CTG-GTT-CGC-CAA- AAA-G (Seq。 ID。 No.22)和AGT-ACG-CAT-CAG-AAA(Seq.Id。No.23)。