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1. 发明申请

US20060253079A1 Stratum corneum piercing device 审中-公开
标题翻译：角质层刺穿装置
公开(公告)号：US20060253079A1
公开(公告)日：2006-11-09
申请号：US11113952
申请日：2005-04-25
申请人： Justin McDonough , Jue-Chen Liu , Ying Sun , Danilo Lambino , Jeffrey Wu , Mariam Maghribi
发明人： Justin McDonough , Jue-Chen Liu , Ying Sun , Danilo Lambino , Jeffrey Wu , Mariam Maghribi
IPC分类号： A61M5/00
CPC分类号： A61M37/0015 , A61B2017/00765 , A61M37/00 , A61M2037/0023 , A61M2037/0046 , A61N1/306 , A61N1/325
摘要： The present invention features a stratum corneum-piercing device including a microprotrusion member having a skin-contacting surface and plurality of stratum corneum piercing microprotrusions thereon, the device being adapted to move the microprotrusion member lateral to the surface of the skin surface upon contact with the skin.
摘要翻译：本发明的特征在于一种角质层穿刺装置，其包括具有皮肤接触表面和多个角质层穿孔微突起的微突出物构件，该装置适于在接触到皮肤表面时将微突出物横向移动到皮肤表面的表面皮肤。

2. 发明申请

US20080009802A1 Method of treating acne with stratum corneum piercing device 审中-公开
标题翻译：用角质层穿刺装置治疗痤疮的方法
公开(公告)号：US20080009802A1
公开(公告)日：2008-01-10
申请号：US11113937
申请日：2005-04-25
申请人： Danilo Lambino , Jue-Chen Liu , Ying Sun , Justin McDonough , Jeffrey Wu , Mariam Maghribi
发明人： Danilo Lambino , Jue-Chen Liu , Ying Sun , Justin McDonough , Jeffrey Wu , Mariam Maghribi
IPC分类号： A61M5/00
CPC分类号： A61N1/30 , A61B17/205 , A61B2017/00747 , A61B2017/00765 , A61M37/0015 , A61M2037/0023 , A61M2037/0046 , A61N1/205 , A61N1/328
摘要： The invention features a method of treating acne by piercing the stratum corneum of skin in need of such treatment with a stratum corneum-piercing device including a microprotrusion member having a skin-contacting surface and plurality of stratum corneum-piercing microprotrusions thereon.
摘要翻译：本发明的特征在于一种通过用角质层刺穿装置刺穿需要这种治疗的皮肤角质层来治疗痤疮的方法，所述角质层穿刺装置包括具有皮肤接触表面的微量输注构件和在其上的多个角质层穿孔微突起。

3. 发明申请

US20060253078A1 Method of treating skin disorders with stratum corneum piercing device 审中-公开
标题翻译：用角质层穿刺装置治疗皮肤病的方法
公开(公告)号：US20060253078A1
公开(公告)日：2006-11-09
申请号：US11113890
申请日：2005-04-25
申请人： Jeffrey Wu , Jue-Chen Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
发明人： Jeffrey Wu , Jue-Chen Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
IPC分类号： A61M5/00
CPC分类号： A61M37/0015 , A61B2017/00765 , A61M37/00 , A61M2037/0023 , A61M2037/0046 , A61N1/306 , A61N1/325
摘要： The present invention features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode; a second conductive electrode; and a reservoir; wherein said power source is in electric communication with said first conductive electrode and said second conductive electrode, wherein said first conductive electrode and said second conductive electrode are arranged such that they are both capable of being in ionic communication with a carrier upon the inclusion of said carrier to said reservoir; and the use thereof.
摘要翻译：本发明的特征在于具有阻挡膜接触表面的装置，该装置包括：电源; 第一导电电极; 第二导电电极; 和一个水库; 其中所述电源与所述第一导电电极和所述第二导电电极电连通，其中所述第一导电电极和所述第二导电电极被布置成使得它们能够在包含所述第一导电电极和所述第二导电电极时能够与载体离子连通载体到所述储存器; 及其用途。

4. 发明申请

US20070049901A1 Method of treating acne with stratum corneum piercing device 审中-公开
标题翻译：用角质层穿刺装置治疗痤疮的方法
公开(公告)号：US20070049901A1
公开(公告)日：2007-03-01
申请号：US11409454
申请日：2006-04-21
申请人： Jeffrey Wu , Jue Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
发明人： Jeffrey Wu , Jue Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
IPC分类号： A61M31/00
CPC分类号： A61M37/0015 , A61B2017/00765 , A61M37/00 , A61M2037/0023 , A61M2037/0046 , A61N1/306 , A61N1/325
摘要： The invention features a method of treating acne by piercing the stratum corneum of skin in need of such treatment with a stratum corneum-piercing device that contains at east one stratum corneum-piercing microprotrusion and a compressible cover such that the compressible cover substantially encases the at least one stratum corneum-piercing microprotrusion, and wherein upon contacting the skin with the compressible cover, the at least one stratum corneum-piercing microprotrusion protrudes from the compressible cover and pierces the stratum corneum of the skin.
摘要翻译：本发明的特征在于一种通过用东方一角质层穿刺微灌注的角质层刺穿装置刺穿需要这种治疗的皮肤角质层来治疗痤疮的方法，使得可压缩盖基本上包围在至少一个角质层刺穿微灌注，并且其中当使皮肤与可压缩覆盖层接触时，至少一个角质层刺穿的微量突出从可压缩盖突出并刺穿皮肤的角质层。

5. 发明申请

US20070270738A1 Method of treating ACNE with stratum corneum piercing patch 审中-公开
标题翻译：用角质层刺穿补片处理ACNE的方法
公开(公告)号：US20070270738A1
公开(公告)日：2007-11-22
申请号：US11690960
申请日：2007-03-26
申请人： Jeffrey Wu , Jue Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
发明人： Jeffrey Wu , Jue Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
IPC分类号： A61B17/20 , A61B17/00
CPC分类号： A61B17/205 , A61B2017/00747
摘要： The invention features a method of treating acne by piercing the stratum corneum of skin in need of such treatment with a stratum corneum-piercing device that contains at least one stratum corneum-piercing microprotrusion and a compressible cover such that the compressible cover substantially encases the at least one stratum corneum-piercing microprotrusion, and wherein upon contacting the skin with the compressible cover, the at least one stratum corneum-piercing microprotrusion protrudes from the compressible cover and pierces the stratum corneum of the skin.
摘要翻译：本发明的特征在于一种通过用包含至少一种角质层穿孔微灌注的角质层刺穿装置刺穿需要这种治疗的皮肤角质层来治疗痤疮的方法，使得可压缩盖基本上包围在至少一个角质层刺穿微灌注，并且其中当使皮肤与可压缩覆盖层接触时，至少一个角质层刺穿的微量突出从可压缩盖突出并刺穿皮肤的角质层。

6. 发明申请

US20060008538A1 Methods of treating the skin 审中-公开
标题翻译：治疗皮肤的方法
公开(公告)号：US20060008538A1
公开(公告)日：2006-01-12
申请号：US11156404
申请日：2005-06-20
申请人： Jeffrey Wu , Jue-Chen Liu , Jeannette Chantalat , Ying Sun , Stefanie Johnsen , Hanuman Jampani
发明人： Jeffrey Wu , Jue-Chen Liu , Jeannette Chantalat , Ying Sun , Stefanie Johnsen , Hanuman Jampani
IPC分类号： A61K33/04
CPC分类号： A61K45/06 , A61K8/368 , A61K8/37 , A61K8/416 , A61K8/42 , A61K31/14 , A61K31/22 , A61K31/23 , A61K31/60 , A61Q19/00 , A61Q19/02 , A61K2300/00
摘要： The invention features a method of (i) reducing the appearance of pores or oil on the skin and (ii) evening skin tone or smoothing skin by applying to an area of skin in need of such treatment a composition including an anti-acne agent, an antimicrobial agent, and a lactate.
摘要翻译：本发明的特征在于：（i）通过施用于需要这种治疗的皮肤区域，减少皮肤上的孔或油的外观和（ii）晚上的肤色或平滑的皮肤，包括抗痤疮剂，抗微生物剂和乳酸盐。

7. 发明授权

US07479133B2 Methods of treating acne and rosacea with galvanic generated electricity 有权
标题翻译：用电生电处理痤疮和酒渣鼻的方法
公开(公告)号：US07479133B2
公开(公告)日：2009-01-20
申请号：US10874917
申请日：2004-06-23
申请人： Ying Sun , Jeffrey Wu , Jue-Chen Liu , Jeannette Chantalat , Aliya Omer
发明人： Ying Sun , Jeffrey Wu , Jue-Chen Liu , Jeannette Chantalat , Aliya Omer
IPC分类号： A61M31/00 , A61N1/30
CPC分类号： A61N1/0492 , A61N1/0428 , A61N1/0436 , A61N1/044 , A61N1/0448 , A61N1/205 , A61N1/325
摘要： The present invention features a method of treating acne or rosacea on the skin by applying electricity to skin in need of such treatment wherein said electricity is generated by a first conductive electrode in electric communication with a second conductive electrode, wherein both the first conductive electrode and the second conductive electrode are in ionic communication with the skin, wherein the difference of the standard potentials of the first conductive electrode and the second conductive electrode is at least 0.2 V and wherein the electrons that pass between the first conductive electrode and the second conductive electrode are generated as a result of such difference of the standard potentials.
摘要翻译：本发明的特征在于一种通过向需要这种治疗的皮肤施加电力来治疗皮肤上的痤疮或红斑痤的方法，其中所述电由与第二导电电极电连通的第一导电电极产生，其中第一导电电极和所述第二导电电极与皮肤离子连通，其中所述第一导电电极和所述第二导电电极的标准电位的差异为至少0.2V，并且其中在所述第一导电电极和所述第二导电电极之间通过的电子是由于这些标准电位的差异而产生的。

8. 发明授权

US07477941B2 Methods of exfoliating the skin with electricity 有权
标题翻译：用电去角质皮肤的方法
公开(公告)号：US07477941B2
公开(公告)日：2009-01-13
申请号：US10874918
申请日：2004-06-23
申请人： Ying Sun , Jeffrey Wu , Jue-Chen Liu
发明人： Ying Sun , Jeffrey Wu , Jue-Chen Liu
IPC分类号： A61N1/30
CPC分类号： A61N1/30 , A61N1/0428 , A61N1/0492 , A61N1/205 , A61N1/325
摘要： The present invention features a method of exfoliating the skin by applying to skin in need of such exfoliating a device including a housing having a skin contacting surface, a first conductive electrode, a second conductive electrode, and a carrier including an agent selected from an alpha-hydroxy acid, beta-hydroxy acid, and salts thereof; wherein the first conductive electrode is in electric communication with the second conductive electrode, wherein the first conductive electrode is in ionic communication with the carrier, wherein the carrier is in communication with the skin contacting surface, and wherein the skin contacting surface is placed in contact with the skin.
摘要翻译：本发明的特征在于一种通过施用于需要这种去角质的装置来剥离皮肤的方法，所述装置包括具有皮肤接触表面的壳体，第一导电电极，第二导电电极和载体，所述载体包括选自α - 羟基酸，β-羟基酸及其盐; 其中所述第一导电电极与所述第二导电电极电连通，其中所述第一导电电极与所述载体离子连通，其中所述载体与所述皮肤接触表面连通，并且其中所述皮肤接触表面接触与皮肤。

9. 发明授权

US07477939B2 Methods of treating a wound with galvanic generated electricity 有权
标题翻译：用电生电处理伤口的方法
公开(公告)号：US07477939B2
公开(公告)日：2009-01-13
申请号：US10874860
申请日：2004-06-23
申请人： Ying Sun , Jeffrey Wu , Jue-Chen Liu , Aliya Omer
发明人： Ying Sun , Jeffrey Wu , Jue-Chen Liu , Aliya Omer
IPC分类号： A61N1/30
CPC分类号： A61N1/30 , A61N1/205 , A61N1/325
摘要： The present invention features a method of treating a wound by applying electricity to a barrier membrane in need of such treatment wherein said electricity is generated by a first conductive electrode in electric communication with a second conductive electrode, wherein both the first conductive electrode and the second conductive electrode are in ionic communication with the barrier membrane, wherein the difference of the standard potentials of the first conductive electrode and the second conductive electrode is at least 0.2 V and wherein the electrons that pass between the first conductive electrode and the second conductive electrode are generated as a result of such difference of the standard potentials.
摘要翻译：本发明的特征在于一种通过向需要这种处理的阻隔膜施加电力来治疗伤口的方法，其中所述电由与第二导电电极电连通的第一导电电极产生，其中第一导电电极和第二导电电极导电电极与阻挡膜离子连通，其中第一导电电极和第二导电电极的标准电位的差异为至少0.2V，并且其中在第一导电电极和第二导电电极之间通过的电子为由于标准电位差异而产生。

10. 发明申请

US20050010161A1 Methods of treating acne and rosacea with galvanic generated electricity 有权
标题翻译：用电生电处理痤疮和酒渣鼻的方法
公开(公告)号：US20050010161A1
公开(公告)日：2005-01-13
申请号：US10874917
申请日：2004-06-23
申请人： Ying Sun , Jeffrey Wu , Jue-Chen Liu , Jeannette Chantalat , Aliya Omer
发明人： Ying Sun , Jeffrey Wu , Jue-Chen Liu , Jeannette Chantalat , Aliya Omer
IPC分类号： A61N1/20 , A61N1/30 , A61N1/32
CPC分类号： A61N1/0492 , A61N1/0428 , A61N1/0436 , A61N1/044 , A61N1/0448 , A61N1/205 , A61N1/325
摘要： The present invention features a method of treating acne or rosacea on the skin by applying electricity to skin in need of such treatment wherein said electricity is generated by a first conductive electrode in electric communication with a second conductive electrode, wherein both the first conductive electrode and the second conductive electrode are in ionic communication with the skin, wherein the difference of the standard potentials of the first conductive electrode and the second conductive electrode is at least 0.2 V and wherein the electrons that pass between the first conductive electrode and the second conductive electrode are generated as a result of such difference of the standard potentials.
摘要翻译：本发明的特征在于一种通过向需要这种治疗的皮肤施加电力来治疗皮肤上的痤疮或红斑痤的方法，其中所述电由与第二导电电极电连通的第一导电电极产生，其中第一导电电极和所述第二导电电极与皮肤离子连通，其中所述第一导电电极和所述第二导电电极的标准电位的差异为至少0.2V，并且其中在所述第一导电电极和所述第二导电电极之间通过的电子是由于这些标准电位的差异而产生的。

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