专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20140005249A1 NKX2.2 INHIBITORS AS DRUGS 审中-公开
标题翻译： NKX2.2作为药物的抑制剂
公开(公告)号：US20140005249A1
公开(公告)日：2014-01-02
申请号：US13811461
申请日：2011-07-21
申请人： Jean-Philippe Hugnot , Pierre-Olivier Guichet , Marisa Teigell , Ivan Bieche , Rosette Lidereau , Dominique Joubert , Luc Bauchet , Valerie Rigau
发明人： Jean-Philippe Hugnot , Pierre-Olivier Guichet , Marisa Teigell , Ivan Bieche , Rosette Lidereau , Dominique Joubert , Luc Bauchet , Valerie Rigau
IPC分类号： C12N15/113 , A61K45/06
CPC分类号： C12N15/113 , A61K31/713 , A61K45/06 , C12N15/115 , C12N2310/11 , C12N2310/14 , C12N2310/16 , C12N2310/531
摘要： The present invention relates to NKX2.2 inhibitors such as shRNAs for treating pathologies.
摘要翻译：本发明涉及NKX2.2抑制剂，例如用于治疗病理学的shRNA。

2. 发明授权

US09487582B2 Methods for treating pancreatic cancer 有权
标题翻译：胰腺癌治疗方法
公开(公告)号：US09487582B2
公开(公告)日：2016-11-08
申请号：US12984522
申请日：2011-01-04
申请人： Leïla Houhou , Dominique Joubert , Frédéric Hollande
发明人： Leïla Houhou , Dominique Joubert , Frédéric Hollande
IPC分类号： C07K16/00 , C07K16/26 , A61K39/395 , C07K16/30 , G01N33/574
CPC分类号： C07K16/26 , A61K39/39558 , C07K16/303 , C07K2317/34 , C07K2317/73 , G01N33/57438 , G01N2333/595 , G01N2800/52
摘要： The present disclosure is directed to methods of treating pancreatic cancer in subject using cancer with antibodies that specifically bind to progastrin.
摘要翻译：本公开涉及使用特异性结合前列腺素的抗体使用癌症治疗患者胰腺癌的方法。

3. 发明授权

US09217032B2 Methods for treating colorectal cancer 有权
标题翻译：治疗结肠直肠癌的方法
公开(公告)号：US09217032B2
公开(公告)日：2015-12-22
申请号：US12984532
申请日：2011-01-04
申请人： Julie Pannequin , Leïla Houhou , Bérénice Framery , Nejla Erkilic , Dominique Joubert , Frédéric Hollande
发明人： Julie Pannequin , Leïla Houhou , Bérénice Framery , Nejla Erkilic , Dominique Joubert , Frédéric Hollande
IPC分类号： A61K39/395 , C07K16/26 , C07K5/107 , C07K16/30 , G01N33/574 , C07K16/22 , A61K39/00
CPC分类号： C07K16/26 , A61K39/39558 , A61K2039/505 , C07K5/1016 , C07K16/3046 , C07K2317/24 , C07K2317/73 , C07K2317/76 , G01N33/57419 , G01N2333/595 , G01N2800/52
摘要： The present disclosure is directed to methods of treating and preventing colorectal cancer metastasis or recurrence of colorectal cancer with compositions comprising anti-progastrin antibodies.
摘要翻译：本公开涉及用包含抗前泌肽抗体的组合物治疗和预防结肠直肠癌转移或结肠直肠癌复发的方法。

4. 发明申请

US20110177063A1 METHODS FOR TREATING COLORECTAL CANCER 有权
标题翻译：治疗癌症的方法
公开(公告)号：US20110177063A1
公开(公告)日：2011-07-21
申请号：US12984532
申请日：2011-01-04
申请人： Julie Pannequin , Leïla Houhou , Bérénice Framery , Nejla Erkilic , Dominique Joubert , Frédéric Hollande
发明人： Julie Pannequin , Leïla Houhou , Bérénice Framery , Nejla Erkilic , Dominique Joubert , Frédéric Hollande
IPC分类号： A61K39/395 , A61P35/00 , G01N33/53
CPC分类号： C07K16/26 , A61K39/39558 , A61K2039/505 , C07K5/1016 , C07K16/3046 , C07K2317/24 , C07K2317/73 , C07K2317/76 , G01N33/57419 , G01N2333/595 , G01N2800/52
摘要： The present disclosure is directed to methods of treating and preventing colorectal cancer metastasis or recurrence of colorectal cancer with compositions comprising anti-progastrin antibodies.
摘要翻译：本公开涉及用包含抗前泌肽抗体的组合物治疗和预防结肠直肠癌转移或结肠直肠癌复发的方法。

5. 发明申请

US20110177062A1 METHODS FOR TREATING BREAST CANCER 有权
标题翻译：治疗乳腺癌的方法
公开(公告)号：US20110177062A1
公开(公告)日：2011-07-21
申请号：US12984509
申请日：2011-01-04
申请人： Jean-François Floch , Leïla Houhou , Françoise Cailler , Dominique Joubert , Frédéric Hollande
发明人： Jean-François Floch , Leïla Houhou , Françoise Cailler , Dominique Joubert , Frédéric Hollande
IPC分类号： A61K39/395 , C12N5/00 , A61P35/00 , G01N33/68
CPC分类号： C07K16/26 , A61K39/39558 , C07K16/303 , C07K2317/34 , C07K2317/73 , G01N33/57438 , G01N2333/595 , G01N2800/52
摘要： The present disclosure is directed to methods of treating and preventing breast cancer or recurrence of breast cancer with compositions comprising anti-progastrin antibodies.
摘要翻译：本公开涉及用包含抗前泌肽抗体的组合物治疗和预防乳腺癌或乳腺癌复发的方法。

6. 发明申请

US20100209426A1 INHIBITORS OF PROGASTRIN-INDUCED REPRESSION OF ICAT FOR TREATING AND/OR PREVENTING COLORECTAL CANCER, ADENOMATOUS POLYPOSIS OR METASTASIS DISPLAYING PROGASTRIN-SECRETING CELLS AND CELLS IN WHICH THE BETA-CATENIN/TCF-MEDIATED TRANSCRIPTIONAL PATHWAY IS CONSTITUTIVELY ACTIVE 审中-公开
标题翻译： PROGASTRIN诱导的ICAT治疗和/或预防色素沉着病，ADENOMATOUS POLYPOSIS或METASTASIS显示PROGASTRIN分泌细胞和细胞的抑制剂，其中β-CATENIN / TCF介导的转录途径是一致的
公开(公告)号：US20100209426A1
公开(公告)日：2010-08-19
申请号：US12301661
申请日：2007-05-21
申请人： Frederic Hollande , Dominique Joubert , Philippe Jay , Julie Pannequin , Nathalie Delaunay , Jean-Francois Bourgaux
发明人： Frederic Hollande , Dominique Joubert , Philippe Jay , Julie Pannequin , Nathalie Delaunay , Jean-Francois Bourgaux
IPC分类号： A61K39/395 , C07K16/26 , C07H21/02 , C12Q1/68 , A61P35/00
CPC分类号： C07K16/26 , C07K2317/34 , C07K2317/76 , C12N15/1135 , C12N15/1136 , C12N2310/111 , C12N2310/14
摘要： The present invention relates to inhibitors of progastrin induced repression of ICAT for treating and/or preventing colorectal cancer, adenomatous polyposis or metastasis displaying progastrin-secreting cells and cells in which the beta-catenin/Tcf-4-mediated transcriptional pathway is constitutively active.
摘要翻译：本发明涉及促胃泌素诱导的ICAT镇压抑制剂，用于治疗和/或预防结直肠癌，腺瘤性息肉病或显示促胃泌素分泌细胞的转移和其中β-连环蛋白/ Tcf-4介导的转录途径是组成型活性的细胞。

7. 发明授权

US10533050B2 Methods and compositions for liver cancer therapy 有权
公开(公告)号：US10533050B2
公开(公告)日：2020-01-14
申请号：US13189403
申请日：2011-07-22
申请人： Leïla Houhou , Anne-Sophie Dumé , Dominique Joubert , Frédéric Hollande
发明人： Leïla Houhou , Anne-Sophie Dumé , Dominique Joubert , Frédéric Hollande
IPC分类号： A61K39/395 , A61K38/22 , A61K39/00 , C07K14/595 , C07K16/26 , A61K45/06
摘要： The present disclosure provides methods of treating liver cancer and preventing liver cancer recurrence with anti-progastrin antibodies, methods of monitoring treatment efficacy of anti-progastrin therapy for liver cancer, and compositions useful therefore.

8. 发明申请

US20150071912A1 PROPHYLAXIS OF COLORECTAL AND GASTROINTESTINAL CANCER 审中-公开
标题翻译：色素和胃肠癌的预防
公开(公告)号：US20150071912A1
公开(公告)日：2015-03-12
申请号：US14233593
申请日：2011-03-23
申请人： Lelïa Houhou , Mathieu Petremann , Dominique Joubert , Frédéric Hollande
发明人： Lelïa Houhou , Mathieu Petremann , Dominique Joubert , Frédéric Hollande
IPC分类号： C07K16/26 , G01N33/574
CPC分类号： C07K16/26 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/57419 , G01N33/57488 , G01N33/74 , G01N2333/5758 , G01N2333/595 , G01N2800/52
摘要： The present disclosure provides methods and compositions useful for preventing gastrointestinal and/or colorectal cancer in animals, including humans, having pre-cancerous adenomatous polyps. The present disclosure provides compositions comprising anti-PG antibodies suitable for use in the methods of the disclosure. The present disclosure also provides methods and compositions useful for monitoring the efficacy of anti-PG treatment in subjects with pre-cancerous polyps.
摘要翻译：本公开提供了用于预防具有癌前腺瘤性息肉的动物（包括人）中的胃肠和/或结肠直肠癌的方法和组合物。本公开提供了包含适合用于本公开的方法的抗PG抗体的组合物。本公开还提供了可用于监测具有癌前息肉的受试者中抗PG治疗的功效的方法和组合物。

9. 发明授权

US5685975A Device for distributing and channeling liquid within a water treatment 失效
标题翻译：在水处理中分配和引导液体的装置
公开(公告)号：US5685975A
公开(公告)日：1997-11-11
申请号：US712391
申请日：1996-09-11
申请人： Dominique Joubert , Michel Pecolatto , Martial Sabatier , Veronique Tharreau , Jean Michel Arribard
发明人： Dominique Joubert , Michel Pecolatto , Martial Sabatier , Veronique Tharreau , Jean Michel Arribard
IPC分类号： C02F1/42 , C02F5/00
CPC分类号： C02F1/42 , C02F2201/006
摘要： A water softening device includes a cylindrical housing with an inlet formed at one end for admitting water to be treated. A filtering material is located in an upstream zone adjacent the inlet. A plate is positioned in relative spaced relation to an opposite end of the housing. A downstream zone, free of filtering material, is located between the plate and the opposite end. Openings are formed in the plate to allow passage of softened water to flow between the upstream and downstream zones. A conduit is axially located in the housing and has a first open end communicating with the downstream zone. A second end of the conduit forms an outlet of the device. A check valve is located at the first end of the conduit for allowing unidirectional flow of water undergoing softening from the downstream zone to the conduit, the check valve restricting flow between the zones during brine regeneration. Channels are formed in the plate and have inlets communicating with the conduit and outlets communicating with the upstream zone for creating a separate flow path, in the absence of water undergoing softening, for a regenerative brine wash directly between the conduit and the filtering material, in a direction opposite that of water undergoing softening.
摘要翻译：水软化装置包括一个圆柱形壳体，其一端形成有一个入口，以允许待处理的水。过滤材料位于与入口相邻的上游区域。板与壳体的相对端相对定位。没有过滤材料的下游区域位于板和相对端之间。在板中形成开口以允许软化水通过在上游和下游区域之间流动。导管轴向地位于壳体中并且具有与下游区域连通的第一开口端。导管的第二端形成装置的出口。止回阀位于管道的第一端，用于允许从下游区域到管道的单向流动软化，止回阀限制盐水再生期间区域之间的流动。通道形成在板中并且具有与导管连接的入口和与上游区连通的出口，用于在没有水经历软化的情况下产生单独的流动路径，用于直接在导管和过滤材料之间的再生卤水洗涤，与正在软化的水相反的方向。

10. 发明授权

US09611320B2 Monoclonal antibodies to progastrin and their uses 有权
公开(公告)号：US09611320B2
公开(公告)日：2017-04-04
申请号：US12906041
申请日：2010-10-15
申请人： Julie Pannequin , Laure Boudier , Dominique Joubert , Frédéric Hollande
发明人： Julie Pannequin , Laure Boudier , Dominique Joubert , Frédéric Hollande
IPC分类号： A61K39/395 , C07K16/26 , A61K39/00
CPC分类号： C07K16/26 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/57419 , G01N33/57488 , G01N2333/595
摘要： The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式