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1. 发明申请

US20110046578A1 DEVICE FOR THE CUTANEOUS APPLICATION OF SUBSTANCES 有权
标题翻译：切实应用物质的设备
公开(公告)号：US20110046578A1
公开(公告)日：2011-02-24
申请号：US12530727
申请日：2008-03-12
申请人： Jean-François Biry , Pascale Ehouarn , Nathalie Donne , Bertrand Dupont
发明人： Jean-François Biry , Pascale Ehouarn , Nathalie Donne , Bertrand Dupont
IPC分类号： A61M35/00
CPC分类号： A61M35/003 , A61B17/20
摘要： The invention relates to a device (1) for cutaneously applying a substance (2), comprising: a patch (3) comprising said substance (2); and a single-use bracelet (4) comprising an irreversible attachment system allowing the substance (2) of the patch (3) to be maintained against the skin of a subject.
摘要翻译：本发明涉及一种用于皮肤施用物质（2）的装置（1），包括：包含所述物质（2）的贴片（3）; 和一次性使用的手镯（4），其包括允许补片（3）的物质（2）保持抵抗受试者皮肤的不可逆附件系统。

2. 发明授权

US08574205B2 Device for the cutaneous application of substances 有权
标题翻译：皮肤应用物质的装置
公开(公告)号：US08574205B2
公开(公告)日：2013-11-05
申请号：US12530727
申请日：2008-03-12
申请人： Jean-François Biry , Pascale Ehouarn , Nathalie Donne , Bertrand Dupont
发明人： Jean-François Biry , Pascale Ehouarn , Nathalie Donne , Bertrand Dupont
IPC分类号： A61M35/00 , A01K29/00
CPC分类号： A61M35/003 , A61B17/20
摘要： The present disclosure provides a device (1) for the cutaneous application of a substance (2) that contains: a patch (3) containing the substance (2); and a single-use wrist strap (4) containing an irreversible attachment system for maintaining the substance (2) of the patch (3) against the skin of a subject.
摘要翻译：本公开提供了一种用于皮肤施用物质（2）的装置（1），其包含：包含所述物质（2）的贴剂（3）; 以及包含用于将贴片（3）的物质（2）保持在受试者的皮肤上的不可逆连接系统的一次性腕带（4）。

3. 发明申请

US20100297213A1 Method For Making Patches By Electrospray 审中-公开
标题翻译：电喷雾贴片方法
公开(公告)号：US20100297213A1
公开(公告)日：2010-11-25
申请号：US12863981
申请日：2009-01-23
申请人： Bertrand Dupont , Ludovic Tatoulian , Pascale Ehouarn
发明人： Bertrand Dupont , Ludovic Tatoulian , Pascale Ehouarn
IPC分类号： B05D3/14 , A61K9/70 , A61K38/02
CPC分类号： B05B5/087 , A61K9/14 , A61K9/7023 , A61K47/645 , B01F13/0076 , B05B5/0255 , B05B5/084 , B05B5/14 , B05D1/04 , B05D2252/04
摘要： The invention relates to patches and methods for manufacturing patches intended for skin application of a substance wherein the patch includes a conductive support, and a liquid formulation of the substance is deposited on the support of the patch by electrohydrodynamic spraying.
摘要翻译：本发明涉及用于制造用于皮肤施用物质的贴片的贴片和方法，其中贴片包括导电支撑体，并且该物质的液体制剂通过电动液体喷涂沉积在贴片的支撑体上。

4. 发明申请

US20100222753A1 Patch With Hydrophilic Adhesive 审中-公开
标题翻译：贴有亲水性胶粘剂
公开(公告)号：US20100222753A1
公开(公告)日：2010-09-02
申请号：US12680893
申请日：2008-09-30
申请人： Bertrand Dupont , Nathalie Donne
发明人： Bertrand Dupont , Nathalie Donne
IPC分类号： A61F13/02 , B05D7/00
CPC分类号： A61K9/703 , A61K8/0208 , A61K8/731 , A61K8/8176 , A61K8/8182 , A61K9/7084 , A61Q19/00
摘要： The invention concerns a patch (1) for application to the skin, comprising: a hydrophilic powder (2) acquiring an adhesive property in the presence of water; a backing (4) having an application side on which the hydrophilic powder (2) is deposited.
摘要翻译：本发明涉及一种用于皮肤的贴剂（1），包括：亲水性粉末（2），在水的存在下获得粘合性; 具有沉积有亲水性粉末（2）的使用侧的背衬（4）。

5. 发明申请

US20100260821A1 Allergen Desensitization Method 有权
标题翻译：过敏原脱敏方法
公开(公告)号：US20100260821A1
公开(公告)日：2010-10-14
申请号：US12745870
申请日：2008-12-03
申请人： Christophe Dupont , Pierre-Henri Benhamou , Bertrand Dupont
发明人： Christophe Dupont , Pierre-Henri Benhamou , Bertrand Dupont
IPC分类号： A61K39/35 , A61K9/70
CPC分类号： A61K39/35 , A61K9/0014 , A61K9/7007 , A61K9/7023 , A61K39/36 , A61K2039/54 , A61K2039/545
摘要： The present application relates to a method for desensitization of allergic patients. More specifically it relates to an epicutaneous desensitization method, applicable to any type of allergens and of patients. The method of the invention is essentially non-invasive and does not require the use of adjuvants. Further, it may be easily applied and monitored by the actual patient.
摘要翻译：本申请涉及一种使过敏患者脱敏的方法。更具体地说，它涉及一种适用于任何类型的变应原和患者的表皮脱敏方法。本发明的方法基本上是非侵入性的，并且不需要使用佐剂。此外，它可以容易地被实际患者应用和监测。

6. 发明授权

US07781734B2 Electronic sensor with integrated thermal regulation 有权
标题翻译：具有集成热调节功能的电子传感器
公开(公告)号：US07781734B2
公开(公告)日：2010-08-24
申请号：US12165888
申请日：2008-07-01
申请人： Gilles Chammings , Bertrand Dupont , Michael Tchagaspanian , Jean-Luc Martin
发明人： Gilles Chammings , Bertrand Dupont , Michael Tchagaspanian , Jean-Luc Martin
IPC分类号： H01L25/00
CPC分类号： G01J5/20 , H04N5/33 , H04N5/335 , H04N5/3745
摘要： A thermal image sensor comprising at least: one pixel matrix, wherein each pixel comprises at least one bolometer and means of applying a voltage to the terminals of the bolometer, and a comparator connecting an output of the pixel matrix to an input of the means of applying the voltage to the terminals of the bolometer of each pixel, wherein said comparator is capable of making a comparison between the output signal of the pixel matrix and a reference value, wherein the value of the voltage at the terminals of the bolometer of each pixel is determined at least partially depending on the result of the comparison.
摘要翻译：一种热图像传感器，至少包括：一个像素矩阵，其中每个像素包括至少一个测辐射热计和向测辐射热计的端子施加电压的装置，以及将像素矩阵的输出连接到将电压施加到每个像素的测辐射热计的端子，其中所述比较器能够对像素矩阵的输出信号和参考值进行比较，其中每个像素的测辐射热计的端子处的电压值至少部分地取决于比较的结果来确定。

7. 发明申请

US20100136093A1 Immunotherapeutic Method For Increasing Groundnut Tolerance In A Subject 有权
标题翻译：免疫治疗方法用于增加一个主题的花生公差
公开(公告)号：US20100136093A1
公开(公告)日：2010-06-03
申请号：US12628077
申请日：2009-11-30
申请人： Lucie Mondoulet , Christophe Dupont , Pierre-Henri Benhamou , Bertrand Dupont
发明人： Lucie Mondoulet , Christophe Dupont , Pierre-Henri Benhamou , Bertrand Dupont
IPC分类号： A61K39/35 , A61K9/70 , A61P37/08
CPC分类号： A61K39/35 , A61K9/0014 , A61K9/7007 , A61K9/7023 , A61K39/36 , A61K2039/54 , A61K2039/545
摘要： The present invention describes a new method for progressive desensitization of a subject to groundnut. More specifically, the invention relates to the immunotherapeutic method for increasing groundnut tolerance in an allergic subject using epicutaneous administration. The present invention is also relative to the use of a skin patch device for progressive desensitization of a subject to groundnut.
摘要翻译：本发明描述了将受试者逐渐脱敏到花生的新方法。更具体地，本发明涉及使用表皮给药来增加过敏性受试者中的花生耐受性的免疫治疗方法。本发明还涉及皮肤贴片装置用于使受试者逐渐脱敏到花生的用途。

8. 发明申请

US20100119586A1 Patch for Cutaneous Application 有权
标题翻译：贴片用于皮肤应用
公开(公告)号：US20100119586A1
公开(公告)日：2010-05-13
申请号：US12527407
申请日：2008-02-15
申请人： Bertrand Dupont
发明人： Bertrand Dupont
IPC分类号： A61K9/70 , A61K39/00 , A61P37/04
CPC分类号： A61K9/703 , A61F13/00987 , A61F13/023 , A61F13/025 , A61F13/0259 , A61K9/7084
摘要： The invention relates to a patch for cutaneous application of a substance, the patch comprising a substance designed to penetrate the epidermis, means for placing the substance in contact with the skin and a peelable cutaneous exfoliation film enabling exfoliation of the skin, after placing the patch, at the level of the contact zone between said substance and the skin.
摘要翻译：本发明涉及一种用于皮肤应用物质的贴剂，该贴剂包括设计成渗透表皮的物质，用于使物质与皮肤接触的装置，以及使贴片贴片之后可剥离皮肤的可剥离皮肤剥离膜在所述物质和皮肤之间的接触区域的水平上。

9. 发明授权

US07635488B2 Patches and uses thereof 有权
标题翻译：补丁及其用途
公开(公告)号：US07635488B2
公开(公告)日：2009-12-22
申请号：US11411531
申请日：2006-04-26
申请人： Christophe Dupont , Bertrand Dupont , Pierre-Yves Vannerom , Pierre-Henri Benhamou , Jorge Ronco
发明人： Christophe Dupont , Bertrand Dupont , Pierre-Yves Vannerom , Pierre-Henri Benhamou , Jorge Ronco
IPC分类号： A61L15/16 , A61N1/30
CPC分类号： A61B10/0035 , A61B2017/00526 , A61F2013/0296 , A61K49/0006
摘要： A patch comprising a support having electrostatic properties is provided wherein a periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is covered with at least one biologically active substance in the form of particles that is adhered to the non-adhesive part of the support by electrostatic forces.
摘要翻译：提供了包括具有静电特性的支持体的贴片，其中支撑体的周边涂覆有粘合剂材料，并且支撑体的全部或部分非粘合表面被至少一种以颗粒形式的生物活性物质覆盖其通过静电力粘附到支撑体的非粘合部分。

10. 发明授权

US08785854B2 Measurement system and imager comprising such a system 有权
标题翻译：包括这样的系统的测量系统和成像器
公开(公告)号：US08785854B2
公开(公告)日：2014-07-22
申请号：US13325498
申请日：2011-12-14
申请人： Bertrand Dupont , Michael Tchagaspanian
发明人： Bertrand Dupont , Michael Tchagaspanian
IPC分类号： G01J5/00 , G02F1/01 , H01L27/00
CPC分类号： G01J5/22
摘要： A measurement system including a reference resistive sensor traversed by a reference current, with a reference arm having a reference resistance and being traversed by the reference current in order to produce a reference voltage between its ends, at least one measurement resistive sensor traversed by a measurement current that depends on a measurement taken by the measurement resistive sensor, a measurement mirror arm traversed by a current, and a device for measuring the difference between the measurement current and the current traversing the measurement mirror arm. The resistance of the measurement mirror arm of each measurement resistive sensor is equal to the reference resistance and the measurement system further includes a device for applying, to each measurement mirror arm, the reference voltage. The device for applying the reference voltage being designed to the isolated to a current of the measurement mirror arm when the reference voltage is applied.
摘要翻译：一种测量系统，包括由参考电流穿过的参考电阻传感器，参考臂具有参考电阻并被参考电流穿过，以便在其端部之间产生参考电压，至少一个测量电阻传感器被测量取决于由测量电阻式传感器测量的电流，由电流穿过的测量镜臂，以及用于测量测量电流与穿过测量镜臂的电流之间的差异的装置。每个测量电阻传感器的测量镜臂的电阻等于参考电阻，并且测量系统还包括用于向每个测量镜臂施加参考电压的装置。当施加参考电压时，用于施加参考电压的装置被设计成隔离到测量镜臂的电流。

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