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1. 发明申请

US20100087758A1 LAMINATED ULTRASONIC WAVEGUIDES FABRICATED FROM SHEET STOCK 审中-公开
标题翻译：层压超声波波纹板
公开(公告)号：US20100087758A1
公开(公告)日：2010-04-08
申请号：US12244289
申请日：2008-10-02
申请人： Jean M. Beaupre , Michael D. Cronin
发明人： Jean M. Beaupre , Michael D. Cronin
IPC分类号： A61N7/00
CPC分类号： A61B17/320068 , A61B2017/320069 , A61B2017/32007 , A61B2017/320082 , A61B2017/320089
摘要： A laminated ultrasonic waveguide and a method of fabrication thereof which comprises stamping at least two pieces of sheet stock to form stamped parts of the laminated ultrasonic waveguide. The stamped parts are then laminated together to form a laminated ultrasonic waveguide for transferring ultrasonic acoustic energy along a longitudinal axis of the laminated ultrasonic waveguide. In several disclosed embodiments, the laminated ultrasonic waveguide is part of an ultrasonic surgical instrument having an active tip end-effector which is placed in contact with tissue of a patient to couple ultrasonic energy transferred along the laminated ultrasonic waveguide to the tissue. The stamped pieces of sheet stock can also be stamped to form one or more channels extending along the length of the laminated ultrasonic waveguide. The laminated ultrasonic waveguide can also define a connector at a proximal end thereof to transfer ultrasonic energy into the laminated ultrasonic waveguide. In different embodiments, the laminated ultrasonic waveguide comprises first and second (and third or more) stamped pieces of sheet stock which are laminated together.
摘要翻译：一种叠层超声波导及其制造方法，包括冲压至少两片片材以形成叠层超声波导的冲压部分。然后将冲压的部件层压在一起以形成层压的超声波波导，用于沿层叠的超声波导的纵向轴传递超声波能量。在几个公开的实施例中，层叠的超声波导是具有活动末端执行器的超声波外科器械的一部分，其被放置成与患者的组织接触以将沿层叠的超声波导传送的超声能量耦合到组织。冲压的片材片也可以冲压成形成沿着层叠的超声波导的长度延伸的一个或多个通道。叠层超声波导还可以在其近端限定连接器，以将超声波能量传递到叠层超声波导中。在不同的实施例中，层压超声波导包括层压在一起的第一和第二（和第三或更多）冲压的片材片。

2. 发明授权

US06561983B2 Attachments of components of ultrasonic blades or waveguides 有权
公开(公告)号：US06561983B2
公开(公告)日：2003-05-13
申请号：US09774908
申请日：2001-01-31
申请人： Michael D. Cronin , Jean M. Beaupre , Lee E. Reichel , Jonathan E. Tuttle
发明人： Michael D. Cronin , Jean M. Beaupre , Lee E. Reichel , Jonathan E. Tuttle
IPC分类号： A61B800
CPC分类号： B06B3/00 , A61B17/320068 , A61B2017/00477 , Y10T29/49863 , Y10T29/4987 , Y10T29/49872 , Y10T403/4933 , Y10T403/4941 , Y10T403/4966
摘要： A connection union and method for securing together first and second components of an ultrasonic waveguide or blade. The first and second components of the ultrasonic waveguide or blade are formed as complementary components which engage each other with a complementary fitting. Then a compressed fit over the connection union is formed by an electromagnetic metal forming operation which compressively deforms a female coupling member over the connection union. The female coupling member can comprise a separate sleeve which is compressed over the connection union by the electromagnetic metal forming operation. Alternatively, the female coupling member can comprise a terminal end of one of the first and second components which includes a longitudinally extending recess which forms an outer circumferentially extending sleeve which is compressed over the connection union by the electromagnetic metal forming operation. In several embodiments, the first and second components are butted together, and each butted end of the first and second components includes at least one circumferentially extending ridge, around which the female coupling member is deformed during the electromagnetic metal forming operation to form an undercut in the female coupling member. In disclosed embodiments, the first component comprises the shaft of an ultrasonic waveguide or blade and the second component comprises a distal tip end of the ultrasonic waveguide such as an end-effector.

3. 发明授权

US08646674B2 Methods and apparatus for delivering tissue treatment compositions to stapled tissue 有权
标题翻译：将组织处理组合物递送到缝合组织的方法和装置
公开(公告)号：US08646674B2
公开(公告)日：2014-02-11
申请号：US12777424
申请日：2010-05-11
申请人： John B. Schulte , Rebecca J. Mollere , Patrick D. Dugan , Michael D. Cronin , Jerome R. Morgan , Stuart K. Morgan , Gary B. McAlister , Tamara S. Vetro Widenhouse , Stephen J. Balek , Joseph P. Schowalter , David A. Witt , Prasanna Malaviya , Frederick E. Shelton, IV
发明人： John B. Schulte , Rebecca J. Mollere , Patrick D. Dugan , Michael D. Cronin , Jerome R. Morgan , Stuart K. Morgan , Gary B. McAlister , Tamara S. Vetro Widenhouse , Stephen J. Balek , Joseph P. Schowalter , David A. Witt , Prasanna Malaviya , Frederick E. Shelton, IV
IPC分类号： A61B17/068
CPC分类号： A61B17/115 , A61B17/00491 , A61B17/07292 , A61B17/1155 , A61B50/30 , A61B2017/00889 , A61B2017/00893 , A61B2050/314
摘要： A surgical stapler includes first and second tissue clamping members and a knife member. The first tissue clamping member is configured to receive a plurality of staples. The second tissue clamping member comprises an anvil configured to form the staples. A tissue treatment member is positionable between the first and second tissue clamping members. The tissue treatment member comprises a rupturable pouch or baffle that is configured to receive a medical fluid including at least one tissue cell. The tissue treatment member may have a spiral shape, an annular disc shape, or an elongate sleeve shape. The tissue treatment member may also include outwardly extending tabs. The tissue treatment member may also include an injection port. In use, the staples and/or the knife pierce the tissue treatment member to release at least a portion of the medical fluid held by the tissue treatment member.
摘要翻译：手术吻合器包括第一和第二组织夹紧构件和刀构件。第一组织夹紧构件构造成容纳多个钉。第二组织夹紧构件包括构造成形成钉的砧座。组织处理构件可定位在第一和第二组织夹紧构件之间。组织处理构件包括可破裂袋或挡板，其构造成接收包括至少一个组织细胞的医用流体。组织处理构件可以具有螺旋形状，环形盘形或细长的套筒形状。组织处理构件还可以包括向外延伸的突片。组织处理构件还可以包括注射口。在使用中，订书针和/或刀刺穿组织处理构件以释放由组织处理构件保持的医用液体的至少一部分。

4. 发明授权

US08491526B2 Therapeutic cell applicator instrument with modular tips 有权
标题翻译：具有模块化提示的治疗细胞施用器械
公开(公告)号：US08491526B2
公开(公告)日：2013-07-23
申请号：US12779477
申请日：2010-05-13
申请人： Michael D. Cronin , Jerome R. Morgan , Patrick D. Dugan , Rebecca J. Mollere , John B. Schulte , David A. Witt , Joseph P. Schowalter , Eugene L. Timperman , Prasanna Malaviya , Shailendra K. Parihar , Shelby L. Cook Kornbluth , Richard W. Timm , Donna L. Korvick , James A. Woodard, Jr. , Peter K. Shires , Barbara L. Mattson , Matthew C. Miller , Frederick E. Shelton, IV
发明人： Michael D. Cronin , Jerome R. Morgan , Patrick D. Dugan , Rebecca J. Mollere , John B. Schulte , David A. Witt , Joseph P. Schowalter , Eugene L. Timperman , Prasanna Malaviya , Shailendra K. Parihar , Shelby L. Cook Kornbluth , Richard W. Timm , Donna L. Korvick , James A. Woodard, Jr. , Peter K. Shires , Barbara L. Mattson , Matthew C. Miller , Frederick E. Shelton, IV
IPC分类号： A61M37/00 , A61M1/00 , A61M5/00
CPC分类号： A61B17/00491 , A61B10/0275 , A61B10/0283 , A61B17/0057 , A61B17/07207 , A61B17/12099 , A61B17/12186 , A61B2017/00495 , A61B2017/00641 , A61B2017/22067 , A61F5/0083 , A61M3/0262 , A61M5/1407 , A61M5/16827 , A61M5/19 , A61M25/10 , A61M2039/1083 , A61M2039/1088 , A61M2205/502 , A61M2210/0662 , A61M2210/1053
摘要： A surgical device comprises a housing, a bioprocessing module, an end effector, and a pumping device. The bioprocessing module comprises media reservoirs, fluid conduits in communication with the reservoirs, and a port through which media is expelled. The end effector is configured for insertion into a lumen and delivering a tissue repair composition into that lumen. The end effector has at least one fluid conduit extending therethrough and at least one orifice in communication with the fluid conduit. The fluid conduit in the first end effector is in fluid communication with the port on the bioprocessing module. The pumping device is operable to urge a tissue repair composition comprising at least a portion of the contents of the media reservoirs through the fluid conduit of the first end effector such that the tissue repair composition is expelled from the at least one orifice.
摘要翻译：手术装置包括壳体，生物处理模块，末端执行器和泵送装置。生物处理模块包括介质储存器，与储存器连通的流体导管以及介质被排出的端口。末端执行器构造成用于插入内腔并将组织修复组合物递送到该内腔中。末端执行器具有延伸穿过其中的至少一个流体导管和与流体导管连通的至少一个孔口。第一末端执行器中的流体导管与生物处理模块上的端口流体连通。抽吸装置可操作以通过第一端部执行器的流体管道促使包含介质容器的内容物的至少一部分的组织修复组合物从组织修复组合物排出至少一个孔口。

5. 发明授权

US08465515B2 Tissue retractors 有权
标题翻译：组织牵开器
公开(公告)号：US08465515B2
公开(公告)日：2013-06-18
申请号：US11846787
申请日：2007-08-29
申请人： Daniel W. Drew , Michael D. Cronin
发明人： Daniel W. Drew , Michael D. Cronin
IPC分类号： A61B17/00
CPC分类号： A61B17/0218 , A61B2017/00557 , A61B2017/00867 , A61B2017/0225
摘要： Methods and devices are provided for performing surgical procedures using tissue retractors. In general, the methods and devices allow a surgeon to use a retractor to capture a large or small amount of tissue in a fabric and to move the fabric to relocate the tissue to one or more convenient locations during the procedure. The flexible nature of the fabric can allow the fabric to be moveable between an open position, in which the fabric can support tissue, and a closed position, in which the fabric can be folded, rolled, or otherwise compressed in size and fit through a port, such as a trocar or an incision in a tissue wall. Furthermore, the position of the fabric and thus the tissue held in the fabric can be adjusted and readjusted by pushing or pulling one or more grasping elements coupled to the fabric.
摘要翻译：提供了用于使用组织牵开器执行外科手术的方法和装置。通常，所述方法和装置允许外科医生使用牵开器在织物中捕获大量或少量的组织，并且在手术过程中移动织物将组织重新定位到一个或多个方便的位置。织物的柔性可以允许织物在织物可以支撑组织的打开位置和关闭位置之间移动，在该位置中，织物可以被折叠，滚动或以其它方式被压缩并且通过端口，例如套管针或组织壁中的切口。此外，可以通过推动或拉动连接到织物的一个或多个抓握元件来调节和重新调整织物的位置，从而保持在织物中的织物的位置。

6. 发明申请

US20110306842A9 Manifold for laparoscopic seal assembly 有权
标题翻译：歧管用于腹腔镜密封组装
公开(公告)号：US20110306842A9
公开(公告)日：2011-12-15
申请号：US11979638
申请日：2007-11-06
申请人： James W. Voegele , Christopher J. Hess , William B. Weisenburgh, II , Robert P. Gill , Daniel W. Drew , Frank L. Lyman , Michael D. Cronin
发明人： James W. Voegele , Christopher J. Hess , William B. Weisenburgh, II , Robert P. Gill , Daniel W. Drew , Frank L. Lyman , Michael D. Cronin
IPC分类号： A61B1/32
CPC分类号： A61B17/3423 , A61B17/3498 , A61B2017/00265 , A61B2017/00438 , A61B2090/308 , A61B2217/005
摘要： A laparoscopic seal assembly includes a seal cap having a seal with an access opening. The seal cap also includes a manifold connection for attachment of a functional apparatus. The seal assembly further includes a retractor.
摘要翻译：腹腔镜密封组件包括具有与入口的密封件的密封帽。密封盖还包括用于附接功能装置的歧管连接件。密封组件还包括牵开器。

7. 发明申请

US20080146884A1 Fully Automated Iris Seal for Hand Assisted Laparoscopic Surgical Procedures 有权
标题翻译：手动辅助腹腔镜手术程序的全自动虹膜密封
公开(公告)号：US20080146884A1
公开(公告)日：2008-06-19
申请号：US11611193
申请日：2006-12-15
申请人： Andrew T. Beckman , Paul T. Franer , Michael D. Cronin
发明人： Andrew T. Beckman , Paul T. Franer , Michael D. Cronin
IPC分类号： A61B17/00
CPC分类号： A61B17/3423 , A61B17/3462 , A61B2017/00265 , A61B2017/00398
摘要： A laparoscopic device assembly provides a tubular diaphragm twist seal that responds to a slight rotation of an actuating ring in a first direction by coupling a motor spring power assisted rotation of a bottom circumference of the twist seal achieves a pneumatic seal in an adjustable access channel defined by the state of the twist seal for maintaining an insufflated body cavity for a hand assisted laparoscopic surgical procedure. A slight rotation of the actuating ring in an opposite second direction releases compression spring energy and energy in the twisted state of the twist seal so that an upper circumference of the twist seal is allowed to open the adjustable access channel.
摘要翻译：腹腔镜装置组件提供管状膜片扭转密封件，其通过联接电动机弹簧对扭转密封件的底部圆周的动力辅助旋转来响应致动环在第一方向上的轻微旋转，从而在限定的可调节进入通道中实现气动密封通过扭转密封件的状态来维持用于手动辅助腹腔镜外科手术的吸入体腔。致动环在相反的第二方向上的轻微旋转在扭转密封的扭转状态下释放压缩弹簧能量和能量，使得扭转密封件的上部周边被允许打开可调节进入通道。

8. 发明授权

US08464925B2 Methods and apparatus for delivering tissue treatment compositions to stapled tissue 有权
标题翻译：将组织处理组合物递送到缝合组织的方法和装置
公开(公告)号：US08464925B2
公开(公告)日：2013-06-18
申请号：US12777449
申请日：2010-05-11
申请人： Joanne Hull , Wells D. Haberstich , Steven G. Hall , John A. Hibner , Julia J. Hwang , Yolanda F. Carter , Frederick E. Shelton, IV , John B. Schulte , Rebecca J. Mollere , Patrick D. Dugan , Michael D. Cronin , Jerome R. Morgan
发明人： Joanne Hull , Wells D. Haberstich , Steven G. Hall , John A. Hibner , Julia J. Hwang , Yolanda F. Carter , Frederick E. Shelton, IV , John B. Schulte , Rebecca J. Mollere , Patrick D. Dugan , Michael D. Cronin , Jerome R. Morgan
IPC分类号： A61B17/04 , A61B17/10
CPC分类号： A61B17/115 , A61B17/00491 , A61B17/07292 , A61B17/1155 , A61B50/30 , A61B2017/00889 , A61B2017/00893 , A61B2050/314
摘要： A surgical stapler includes first and second tissue clamping members and a reservoir configured to hold a tissue treatment composition. The first tissue clamping member is configured to receive a plurality of staples. The second tissue clamping member comprises an anvil configured to form the staples. The reservoir may be provided in a handle portion of the surgical stapler, and a fluid conduit may be used to communicate the tissue treatment composition from the reservoir. An end effector lumen may selectively communicate with the fluid conduit. The lumen may also be in communication with openings to further communicate the tissue treatment composition to tissue or to a scaffold material positioned adjacent to tissue. A reservoir may alternatively be provided in one of the clamping members. A knife member may pierce a housing defining the reservoir, and a resilient member may then urge a tissue treatment composition from the housing.
摘要翻译：手术吻合器包括第一和第二组织夹紧构件和构造成保持组织处理组合物的储存器。第一组织夹紧构件构造成容纳多个钉。第二组织夹紧构件包括构造成形成钉的砧座。储存器可以设置在外科缝合器的手柄部分中，并且流体导管可用于将组织处理组合物与储存器连通。末端执行器腔可以选择性地与流体导管连通。内腔还可以与开口连通，以进一步将组织处理组合物传递到组织或邻近组织定位的支架材料。也可以在一个夹紧构件中设置储存器。刀构件可以刺穿限定储存器的壳体，并且弹性构件然后可以从壳体推动组织处理组合物。

9. 发明申请

US20110282446A1 Methods and Apparatus for Delivering Tissue Treatment Compositions to Stapled Tissue 有权
标题翻译：用于将组织处理组合物递送至装订组织的方法和装置
公开(公告)号：US20110282446A1
公开(公告)日：2011-11-17
申请号：US12777424
申请日：2010-05-11
申请人： John B. Schulte , Rebecca J. Mollere , Patrick D. Dugan , Michael D. Cronin , Jerome R. Morgan , Stuart K. Morgan , Gary B. McAlister , Tamara S. Vetro Widenhouse , Stephen J. Balek , Joseph P. Schowalter , David A. Witt , Prasanna Malaviya , Frederick E. Shelton, IV
发明人： John B. Schulte , Rebecca J. Mollere , Patrick D. Dugan , Michael D. Cronin , Jerome R. Morgan , Stuart K. Morgan , Gary B. McAlister , Tamara S. Vetro Widenhouse , Stephen J. Balek , Joseph P. Schowalter , David A. Witt , Prasanna Malaviya , Frederick E. Shelton, IV
IPC分类号： A61B17/068 , A61F2/02 , A61B10/02
CPC分类号： A61B17/115 , A61B17/00491 , A61B17/07292 , A61B17/1155 , A61B50/30 , A61B2017/00889 , A61B2017/00893 , A61B2050/314
摘要： A surgical stapler includes first and second tissue clamping members and a knife member. The first tissue clamping member is configured to receive a plurality of staples. The second tissue clamping member comprises an anvil configured to form the staples. A tissue treatment member is positionable between the first and second tissue clamping members. The tissue treatment member comprises a rupturable pouch or baffle that is configured to receive a medical fluid including at least one tissue cell. The tissue treatment member may have a spiral shape, an annular disc shape, or an elongate sleeve shape. The tissue treatment member may also include outwardly extending tabs. The tissue treatment member may also include an injection port. In use, the staples and/or the knife pierce the tissue treatment member to release at least a portion of the medical fluid held by the tissue treatment member.
摘要翻译：手术吻合器包括第一和第二组织夹紧构件和刀构件。第一组织夹紧构件构造成容纳多个钉。第二组织夹紧构件包括构造成形成钉的砧座。组织处理构件可定位在第一和第二组织夹紧构件之间。组织处理构件包括可破裂袋或挡板，其构造成接收包括至少一个组织细胞的医用流体。组织处理构件可以具有螺旋形状，环形盘形或细长的套筒形状。组织处理构件还可以包括向外延伸的突片。组织处理构件还可以包括注射口。在使用中，订书针和/或刀刺穿组织处理构件以释放由组织处理构件保持的医用液体的至少一部分。

10. 发明申请

US20110282242A1 Instrument for Applying Therapeutic Cells, with Proximal Portion for Processing Therapeutic Cells 有权
标题翻译：用于治疗细胞应用的方法，用于处理治疗细胞的近端部分
公开(公告)号：US20110282242A1
公开(公告)日：2011-11-17
申请号：US12777491
申请日：2010-05-11
申请人： Michael D. Cronin , Patrick D. Dugan , Shelby L. Cook Kornbluth , Donna L. Korvick , Rebecca J. Mollere , Jerome R. Morgan , Shailendra K. Parihar , John B. Schulte , Richard W. Timm
发明人： Michael D. Cronin , Patrick D. Dugan , Shelby L. Cook Kornbluth , Donna L. Korvick , Rebecca J. Mollere , Jerome R. Morgan , Shailendra K. Parihar , John B. Schulte , Richard W. Timm
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B10/0283
摘要： A tissue harvesting and processing apparatus comprises a body and a distally extending needle. The needle includes an aperture configured to receive tissue. A tissue cutting member is movable relative to the needle to sever a specimen from tissue protruding through the aperture. A tissue processor is operable to mince tissue severed by the tissue cutting member. The minced tissue may be mixed with a medical fluid component contained in a reservoir. The medical fluid mixture may be expelled through an applier tip coupled with the body. The tissue processor may comprise a mincing die such that tissue specimens are minced upon being extruded through the mincing die. The tissue processor may comprise a blade that cooperates with a sliding press. The tissue processor may comprise auger blade sections that cooperate with inwardly extending pins. A mixing piston may mix the minced tissue with the medical fluid component.
摘要翻译：组织采集和处理装置包括主体和远端延伸的针。针包括构造成接收组织的孔。组织切割构件可相对于针移动，以从通过孔突出的组织切断样本。组织处理器可操作以切碎由组织切割构件切断的组织。切碎的组织可以与容纳在容器中的医用液体组分混合。药物流体混合物可以通过与身体联接的施放器尖端排出。组织处理器可以包括切割模具，使得组织样本在通过切割模具挤出时被切碎。组织处理器可以包括与滑动压机配合的叶片。组织处理器可以包括与向内延伸的销配合的螺旋刀片部分。混合活塞可将切碎的组织与医用液体组分混合。

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