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1. 发明申请

US20110046499A1 RESPIRATORY MONITORS AND MONITORING METHODS 有权
标题翻译：呼吸监测器和监测方法
公开(公告)号：US20110046499A1
公开(公告)日：2011-02-24
申请号：US12989484
申请日：2009-05-04
申请人： Jasper Klewer , Haris durIic , Teunis Jan Ikkink
发明人： Jasper Klewer , Haris durIic , Teunis Jan Ikkink
IPC分类号： A61B5/08
CPC分类号： A61B5/113 , A61B5/0816 , A61B7/003 , A61B2562/0219 , H04B17/0085
摘要： A respiratory monitor comprises: a first sensor (20, 70) configured to generate a respiration-related motion monitoring signal (72) indicative of respiration related motion; a second sensor (20, 22, 80, 82) configured to generate a sound monitoring signal (84) indicative of respiration-related sound; and a signals synthesizer (90) configured to synthesize a respiratory monitor signal (46) based on the respiration-related motion monitoring signal and the respiration-related sound monitoring signal. A sensor for use in respiratory monitoring comprises an accelerometer (30) and a magnetometer (32) together defining a unitary sensor (20) configured for attachment to a respiring subject (10) so as to move as a unit responsive to respiration related motion of the respiring subject.
摘要翻译：呼吸监测器包括：第一传感器（20,70），被配置为产生指示呼吸相关运动的呼吸相关运动监测信号（72）被配置为产生指示呼吸相关声音的声音监测信号（84）的第二传感器（20,22，80,82）以及信号合成器（90），被配置为基于与呼吸相关的运动监视信号和呼吸相关声音监测信号合成呼吸监测信号（46）。用于呼吸监测的传感器包括加速度计（30）和磁力计（32），所述加速度计（30）和磁力计（32）一起限定一个单一传感器（20），其被配置为附接到呼吸对象（10），以便作为响应于呼吸相关运动的单元呼吸科目。

2. 发明授权

US10052048B2 Respiratory monitors and monitoring methods 有权
公开(公告)号：US10052048B2
公开(公告)日：2018-08-21
申请号：US12989484
申请日：2009-05-04
申请人： Jasper Klewer , Haris Duric , Teunis Jan Ikkink
发明人： Jasper Klewer , Haris Duric , Teunis Jan Ikkink
IPC分类号： A61B5/08 , A61B5/113 , A61B7/00 , H04B17/00
CPC分类号： A61B5/113 , A61B5/0816 , A61B7/003 , A61B2562/0219 , H04B17/0085
摘要： A respiratory monitor comprises: a first sensor (20, 70) configured to generate a respiration-related motion monitoring signal (72) indicative of respiration related motion; a second sensor (20, 22, 80, 82) configured to generate a sound monitoring signal (84) indicative of respiration-related sound; and a signals synthesizer (90) configured to synthesize a respiratory monitor signal (46) based on the respiration-related motion monitoring signal and the respiration-related sound monitoring signal. A sensor for use in respiratory monitoring comprises an accelerometer (30) and a magnetometer (32) together defining a unitary sensor (20) configured for attachment to a respiring subject (10) so as to move as a unit responsive to respiration related motion of the respiring subject.

3. 发明授权

US08845187B2 Zero heat flux temperature sensing device 有权
标题翻译：零热通量温度传感装置
公开(公告)号：US08845187B2
公开(公告)日：2014-09-30
申请号：US13202627
申请日：2010-03-04
申请人： Jasper Klewer , Amy O. M. Cheung
发明人： Jasper Klewer , Amy O. M. Cheung
IPC分类号： G01K17/00 , G01K3/00 , G01K7/00 , G01N25/00 , G01K13/00 , G01K1/16
CPC分类号： G01K1/16 , G01K1/165 , G01K13/002
摘要： The invention relates to a zero heat flux temperature sensing device (100) for sensing a core body temperature of an object (113). The zero heat flux temperature sensing device (100) comprises a layer (107), a first temperature gradient sensor (105), a first heat flux modulator (103) and a heat flux modulator controller (102). The layer (107) has an opposing first side (112) and second side (108). In use the first side (112) is nearest to the object (113). The layer (107) is for obtaining a first temperature difference over the layer (107) in response to a first heat flux in a first direction from the first side (112) to the second side (108). The first temperature gradient sensor (105) senses at the first side (112) of the layer (107) a second temperature difference in a second direction. The second direction extends from a first border of the first side (112) towards a second border of the first side (112). The first heat flux modulator (103) is arranged at the first side (112) of the layer (107) and is constructed to change a second heat flux in a second direction at the first side (112) of the layer (107) in order to influence the second temperature difference. The heat flux modulator controller (102) controls the first heat flux modulator (103) on basis of the sensed second temperature difference in order to decrease an absolute value of the second temperature difference. The effect of the measures according to the invention is that the zero heat flux temperature sensing device (100) senses the core body temperature of the object (113) more accurately.
摘要翻译：本发明涉及一种用于感测物体（113）的核心体温的零热通量温度感测装置（100）。零热通量温度感测装置（100）包括层（107），第一温度梯度传感器（105），第一热通量调制器（103）和热通量调节器控制器（102）。层（107）具有相对的第一侧（112）和第二侧（108）。在使用中，第一侧（112）最靠近物体（113）。层（107）用于响应于从第一侧（112）到第二侧（108）的第一方向上的第一热通量，在层（107）上获得第一温度差。第一温度梯度传感器（105）在层（107）的第一侧（112）处感测第二方向上的第二温度差。第二方向从第一侧（112）的第一边界延伸到第一侧（112）的第二边界。第一热通量调节器（103）布置在层（107）的第一侧（112）处，并且被构造成在层（107）的第一侧（112）处沿第二方向改变第二热通量，为了影响第二个温差。热通量调节器控制器（102）基于感测到的第二温差来控制第一热通量调节器（103），以便减小第二温度差的绝对值。根据本发明的措施的效果是，零热通量温度感测装置（100）更准确地感测物体（113）的核心体温。

4. 发明授权

US08716629B2 Temperature sensor for body temperature measurement 有权
标题翻译：温度传感器，用于体温测量
公开(公告)号：US08716629B2
公开(公告)日：2014-05-06
申请号：US13262241
申请日：2010-04-01
申请人： Jasper Klewer , Amy Cheung , Liesbeth Van Pieterson , Erik Bakkers
发明人： Jasper Klewer , Amy Cheung , Liesbeth Van Pieterson , Erik Bakkers
IPC分类号： H05B1/00 , G01K1/08
CPC分类号： G01K1/16 , A41D13/1281 , A61B5/0008 , A61B5/01 , A61B5/6804 , G01K1/14 , G01K1/165 , G01K13/002 , G01K2217/00
摘要： This invention relates to a temperature sensor for body temperature measurements. The temperature sensor is made of several layers, where a first layer has a central heater embedded therein, a second layer which is attached to the first layer has at least one first thermistor embedded therein for measuring a first temperature value, a third layer has at one ore second thermistor embedded therein separated from the first thermistor for measuring at least one second temperature value, but this third layer is adapted to be in contact to the skin of the surface of the body for conducting the heat escaping from the body through the layers. The difference between the first and the second temperature values indicates the heat flux from the body. The heat emitted from central heater is tuned oppositely to the heat flux until a zero heat flux is reached, where the temperature at the at least one second thermistor at zero heat flux indicates the body temperature. These layers are fabric layers.
摘要翻译：本发明涉及一种用于体温测量的温度传感器。温度传感器由多层构成，其中第一层具有嵌入其中的中央加热器，附接到第一层的第二层具有嵌入其中的至少一个第一热敏电阻，用于测量第一温度值，第三层具有嵌入其中的与第一热敏电阻分离的一个第二热敏电阻用于测量至少一个第二温度值，但是该第三层适于与身体表面的皮肤接触，用于导致从身体排出的热量通过层。第一和第二温度值之间的差值表示来自身体的热通量。从中央加热器发出的热量与热通量相反地调节，直到达到零热通量，其中在零热通量下的至少一个第二热敏电阻的温度表示体温。这些层是织物层。

5. 发明授权

US08602642B2 Contact detection device for detecting a physical contact between the contact detection device and an object 有权
标题翻译：用于检测接触检测装置和物体之间的物理接触的接触检测装置
公开(公告)号：US08602642B2
公开(公告)日：2013-12-10
申请号：US13383295
申请日：2010-07-07
申请人： Jasper Klewer
发明人： Jasper Klewer
IPC分类号： G01N25/18
CPC分类号： G01K7/42 , A61B5/01 , A61B5/6843 , G01K13/002
摘要： The present invention is related to a contact detection device (100) for detecting a contact between the contact detection device (100) and an object (800), a method (400), a diagnostic device and further to a computer program. The invention seeks to improve the reliability of contact sensors. The contact detection device (100) comprises a heater (110) for providing a modulated heat flow (112). A modulated heat signal (122) is generated in dependence of the modulated heat flow (112). A physical contact with an object (800) causes a change in the modulated heat flow (112) that effects the modulated heat signal (122). As the heat flow is modulated, a change in the modulated heat signal (122) is quasi assured. A contact determination unit (130) of the contact detection device (100) derives a contact indication signal (132) indicating at least either the presence or the absence of the physical contact in from the modulated heat (122), preferentially by means of a demodulator (134).
摘要翻译：本发明涉及用于检测接触检测装置（100）和物体（800）之间的接触的接触检测装置（100），方法（400），诊断装置以及计算机程序。本发明寻求提高接触传感器的可靠性。接触检测装置（100）包括用于提供调制热流（112）的加热器（110）。根据调制的热流（112）产生调制的热信号（122）。与物体（800）的物理接触导致影响调制热信号（122）的调制热流（112）的变化。随着热流被调制，调制热信号（122）的变化是准确的。接触检测装置（100）的接触确定单元（130）导出接触指示信号（132），其指示来自调制热（122）的物理接触的存在或不存在的至少一个，优选地借助于解调器（134）。

6. 发明申请

US20120106592A1 CONTACT DETECTION DEVICE FOR DETECTING A PHYSICAL CONTACT BETWEEN THE CONTACT DETECTION DEVICE AND AN OBJECT 有权
标题翻译：用于检测接触检测装置与物体之间的物理接触点的接触检测装置
公开(公告)号：US20120106592A1
公开(公告)日：2012-05-03
申请号：US13383295
申请日：2010-07-07
申请人： Jasper Klewer
发明人： Jasper Klewer
IPC分类号： G01N25/00
CPC分类号： G01K7/42 , A61B5/01 , A61B5/6843 , G01K13/002
摘要： The present invention is related to a contact detection device (100) for detecting a contact between the contact detection device (100) and an object (800), a method (400), a diagnostic device and further to a computer program. The invention seeks to improve the reliability of contact sensors. The contact detection device (100) comprises a heater (110) for providing a modulated heat flow (112). A modulated heat signal (122) is generated in dependence of the modulated heat flow (112). A physical contact with an object (800) causes a change in the modulated heat flow (112) that effects the modulated heat signal (122). As the heat flow is modulated, a change in the modulated heat signal (122) is quasi assured. A contact determination unit (130) of the contact detection device (100) derives a contact indication signal (132) indicating at least either the presence or the absence of the physical contact in from the modulated heat (122), preferentially by means of a demodulator (134).
摘要翻译：本发明涉及用于检测接触检测装置（100）和物体（800）之间的接触的接触检测装置（100），方法（400），诊断装置以及计算机程序。本发明寻求提高接触传感器的可靠性。接触检测装置（100）包括用于提供调制热流（112）的加热器（110）。根据调制的热流（112）产生调制的热信号（122）。与物体（800）的物理接触导致影响调制热信号（122）的调制热流（112）的变化。随着热流被调制，调制热信号（122）的变化是准确的。接触检测装置（100）的接触确定单元（130）导出接触指示信号（132），其指示来自调制热（122）的物理接触的存在或不存在的至少一个，优选地借助于解调器（134）。

7. 发明申请

US20120024833A1 TEMPERATURE SENSOR FOR BODY TEMPERATURE MEASUREMENT 有权
标题翻译：温度传感器用于体温测量
公开(公告)号：US20120024833A1
公开(公告)日：2012-02-02
申请号：US13262241
申请日：2010-04-01
申请人： Jasper Klewer , Amy Cheung , Liesbeth Van Pieterson , Erik Bakkers
发明人： Jasper Klewer , Amy Cheung , Liesbeth Van Pieterson , Erik Bakkers
IPC分类号： H05B1/00
CPC分类号： G01K1/16 , A41D13/1281 , A61B5/0008 , A61B5/01 , A61B5/6804 , G01K1/14 , G01K1/165 , G01K13/002 , G01K2217/00
摘要： This invention relates to a temperature sensor for body temperature measurements. The temperature sensor is made of several layers, where a first layer has a central heater embedded therein, a second layer which is attached to the first layer has at least one first thermistor embedded therein for measuring a first temperature value, a third layer has at one ore second thermistor embedded therein separated from the first thermistor for measuring at least one second temperature value, but this third layer is adapted to be in contact to the skin of the surface of the body for conducting the heat escaping from the body through the layers. The difference between the first and the second temperature values indicates the heat flux from the body. The heat emitted from central heater is tuned oppositely to the heat flux until a zero heat flux is reached, where the temperature at the at least one second thermistor at zero heat flux indicates the body temperature. These layers are fabric layers.
摘要翻译：本发明涉及一种用于体温测量的温度传感器。温度传感器由多层构成，其中第一层具有嵌入其中的中央加热器，附接到第一层的第二层具有嵌入其中的至少一个第一热敏电阻，用于测量第一温度值，第三层具有嵌入其中的与第一热敏电阻分离的一个第二热敏电阻用于测量至少一个第二温度值，但是该第三层适于与身体表面的皮肤接触，用于导致从身体排出的热量通过层。第一和第二温度值之间的差值表示来自身体的热通量。从中央加热器发出的热量与热通量相反地调节，直到达到零热通量，其中在零热通量下的至少一个第二热敏电阻的温度表示体温。这些层是织物层。

8. 发明申请

US20110317737A1 ZERO HEAT FLUX TEMPERATURE SENSING DEVICE 有权
标题翻译：零热通量温度传感装置
公开(公告)号：US20110317737A1
公开(公告)日：2011-12-29
申请号：US13202627
申请日：2010-03-04
申请人： Jasper Klewer , Amy O. M. Cheung
发明人： Jasper Klewer , Amy O. M. Cheung
IPC分类号： G01K17/00
CPC分类号： G01K1/16 , G01K1/165 , G01K13/002
摘要： The invention relates to a zero heat flux temperature sensing device (100) for sensing a core body temperature of an object (113). The zero heat flux temperature sensing device (100) comprises a layer (107), a first temperature gradient sensor (105), a first heat flux modulator (103) and a heat flux modulator controller (102). The layer (107) has an opposing first side (112) and second side (108). In use the first side (112) is nearest to the object (113). The layer (107) is for obtaining a first temperature difference over the layer (107) in response to a first heat flux in a first direction from the first side (112) to the second side (108). The first temperature gradient sensor (105) senses at the first side (112) of the layer (107) a second temperature difference in a second direction. The second direction extends from a first border of the first side (112) towards a second border of the first side (112). The first heat flux modulator (103) is arranged at the first side (112) of the layer (107) and is constructed to change a second heat flux in a second direction at the first side (112) of the layer (107) in order to influence the second temperature difference. The heat flux modulator controller (102) controls the first heat flux modulator (103) on basis of the sensed second temperature difference in order to decrease an absolute value of the second temperature difference. The effect of the measures according to the invention is that the zero heat flux temperature sensing device (100) senses the core body temperature of the object (113) more accurately.
摘要翻译：本发明涉及一种用于感测物体（113）的核心体温的零热通量温度感测装置（100）。零热通量温度感测装置（100）包括层（107），第一温度梯度传感器（105），第一热通量调制器（103）和热通量调节器控制器（102）。层（107）具有相对的第一侧（112）和第二侧（108）。在使用中，第一侧（112）最靠近物体（113）。层（107）用于响应于从第一侧（112）到第二侧（108）的第一方向上的第一热通量，在层（107）上获得第一温度差。第一温度梯度传感器（105）在层（107）的第一侧（112）处感测第二方向上的第二温度差。第二方向从第一侧（112）的第一边界延伸到第一侧（112）的第二边界。第一热通量调节器（103）布置在层（107）的第一侧（112）处，并且被构造成在层（107）的第一侧（112）处沿第二方向改变第二热通量，为了影响第二个温差。热通量调节器控制器（102）基于感测到的第二温差来控制第一热通量调节器（103），以便减小第二温度差的绝对值。根据本发明的措施的效果是，零热通量温度感测装置（100）更准确地感测物体（113）的核心体温。

9. 发明授权

US09916424B2 Early exacerbation detection using differential temperature monitoring 有权
公开(公告)号：US09916424B2
公开(公告)日：2018-03-13
申请号：US13518066
申请日：2010-11-17
申请人： Amy Oi Mee Cheung , Jasper Klewer , Maryam Atakhorrami
发明人： Amy Oi Mee Cheung , Jasper Klewer , Maryam Atakhorrami
IPC分类号： A61B5/00 , G06F19/00
CPC分类号： G16H50/20 , G06F19/00 , G16H15/00
摘要： A system and method for predicting an onset of an exacerbation in a patient is provided. The method includes monitoring core body temperature of the patient; monitoring breath temperature of the patient; calculating a relationship, or a change in relationship, between the core body temperature and the breath temperature of the patient; and detecting the onset of the exacerbation, when the calculated relationship, or a change in relationship, satisfies a predetermined criteria.

10. 发明授权

US08945020B2 Zero heat flux sensor and method of use 有权
标题翻译：零热通量传感器及使用方法
公开(公告)号：US08945020B2
公开(公告)日：2015-02-03
申请号：US13144701
申请日：2009-12-23
申请人： Amy Oi Mee Cheung , Jasper Klewer
发明人： Amy Oi Mee Cheung , Jasper Klewer
IPC分类号： A61B5/00 , G01K1/14 , G01K1/16 , G01K7/21 , G01K13/00
CPC分类号： G01K1/14 , G01K1/16 , G01K1/165 , G01K7/21 , G01K13/002
摘要： When measuring core body temperature in a patient, a curved sensor (10) is provide that has a predefined radius of curvature to fit comfortably and closely to a patient's forehead. The sensor (10) has at least one releasable securing strip (e.g., Velcro™) that couples the sensor (10) to a headband (14), as well as an adhesive strip (16) that is positioned along one edge of an interior surface of the sensor (10) and couples the sensor (10) to the patient's skin. The adhesive strip acts as a hinge that facilitates inspection of the skin beneath the sensor without complete removal of the sensor, and the headband and curvature of the sensor provide a snug fit of the interior surface of the sensor against the patient's skin. Additionally, the sensor may be a zero heat flux sensor (34) with a heater (32) placed on one side thereof and a thermister (36) placed on an opposite side thereof, between the heat flux sensor (34) and a patient's skin. The heater is adjusted until heat flux through the heat flux sensor is zero, at which point the patient's skin surface temperature (as detected by the thermistor) is recorded as a core body temperature. Moreover, the thermister (34, 72) may be quickly calibrated by linearizing a temperature vs. resistance curve therefore, and shifting the linearized curve to a predetermined 15 reference curve.
摘要翻译：当测量患者体内的体温时，提供弯曲的传感器（10），其具有预定的曲率半径以适合和紧密地配合患者的前额。传感器（10）具有将传感器（10）连接到头带（14）的至少一个可释放的固定条（例如，Velcro TM）以及沿内部的一个边缘定位的粘合带（16）传感器（10）的表面并将传感器（10）耦合到患者的皮肤上。粘合带作为铰链，其有助于检查传感器下方的皮肤，而不会完全移除传感器，并且传感器的头带和曲率提供传感器内表面贴合患者皮肤的贴合配合。另外，传感器可以是零热通量传感器（34），其一侧放置有加热器（32），并且在热通量传感器（34）和患者皮肤之间放置热敏电阻（36）。调节加热器，直到通过热通量传感器的热通量为零，此时患者的皮肤表面温度（由热敏电阻检测）记录为核心体温。此外，可以通过线性化温度与电阻曲线来快速校准热敏电阻（34,72），并将线性化曲线移动到预定的15个参考曲线。

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