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1. 发明授权

US09916424B2 Early exacerbation detection using differential temperature monitoring 有权
公开(公告)号：US09916424B2
公开(公告)日：2018-03-13
申请号：US13518066
申请日：2010-11-17
申请人： Amy Oi Mee Cheung , Jasper Klewer , Maryam Atakhorrami
发明人： Amy Oi Mee Cheung , Jasper Klewer , Maryam Atakhorrami
IPC分类号： A61B5/00 , G06F19/00
CPC分类号： G16H50/20 , G06F19/00 , G16H15/00
摘要： A system and method for predicting an onset of an exacerbation in a patient is provided. The method includes monitoring core body temperature of the patient; monitoring breath temperature of the patient; calculating a relationship, or a change in relationship, between the core body temperature and the breath temperature of the patient; and detecting the onset of the exacerbation, when the calculated relationship, or a change in relationship, satisfies a predetermined criteria.

2. 发明申请

US20120302911A1 EARLY EXACERBATION DETECTION USING DIFFERENTIAL TEMPERATURE MOITORING 有权
标题翻译：使用差分温度移动的早期实时检测
公开(公告)号：US20120302911A1
公开(公告)日：2012-11-29
申请号：US13518066
申请日：2010-11-17
申请人： Amy Oi Mee Cheung , Jasper Klewer , Maryam Atakhorrami
发明人： Amy Oi Mee Cheung , Jasper Klewer , Maryam Atakhorrami
IPC分类号： A61B5/01
CPC分类号： G16H50/20 , G06F19/00 , G16H15/00
摘要： A system and method for predicting an onset of an exacerbation in a patient is provided. The method includes monitoring core body temperature of the patient; monitoring breath temperature of the patient; calculating a relationship, or a change in relationship, between the core body temperature and the breath temperature of the patient; and detecting the onset of the exacerbation, when the calculated relationship, or a change in relationship, satisfies a predetermined criteria.
摘要翻译：提供了一种用于预测患者恶化发作的系统和方法。该方法包括监测患者的核心体温; 监测患者的呼吸温度; 计算核心体温和患者的呼吸温度之间的关系或关系的变化; 并且当所计算的关系或关系的变化满足预定标准时，检测恶化的发作。

3. 发明授权

US09996677B2 System and method for obtaining an objective measure of dyspnea 有权
公开(公告)号：US09996677B2
公开(公告)日：2018-06-12
申请号：US13583072
申请日：2011-02-14
申请人： Amy Oi Mee Cheung , Maryam Atakhorrami
发明人： Amy Oi Mee Cheung , Maryam Atakhorrami
IPC分类号： A61B5/00 , G06F19/00 , A61B5/08 , A61B5/11 , A61B5/113 , A61B7/00
CPC分类号： G16H15/00 , A61B5/0816 , A61B5/1118 , A61B5/1135 , A61B5/6804 , A61B5/681 , A61B5/6824 , A61B5/6831 , A61B7/003 , G06F19/00 , G16H10/20 , G16H50/20
摘要： A computer-implemented method for assessing a level of dyspnea in a patient is provided. The method includes measuring physical activity of the patient over a period of time with an activity monitor to gather physical activity data; measuring respiration rate of the patient over the period of time with a respiration rate sensor to gather respiration rate data; administering a questionnaire to gather clinical information of the patient; and executing, on one or more computer processors, one or more computer program modules to determine a dyspnea value for the patient based on the respiration rate data, the physical activity data, and the clinical information of the patient. The dyspnea value is representative of the level of dyspnea in the patient.

4. 发明授权

US09465893B2 Biofeedback for program guidance in pulmonary rehabilitation 有权
标题翻译：肺康复方案指导生物反馈
公开(公告)号：US09465893B2
公开(公告)日：2016-10-11
申请号：US13518075
申请日：2010-11-17
申请人： Amy Oi Mee Cheung , Maryam Atakhorrami
发明人： Amy Oi Mee Cheung , Maryam Atakhorrami
IPC分类号： G06F17/00 , G06F17/40 , G06F19/00
CPC分类号： G06F17/40 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： A system (200) for providing an exercise training plan for a patient is provided. The system includes a sensor (202, 204, 206, 208, 210, 212), and a processor (214) operatively connected to the at least one sensor. The sensor measures physiological parameter of the patient. The processor is configured to: a) receive health information data representative of patient information and patient symptoms; b) receive physiological data from the at least one sensor; c) devise the exercise training plan for the patient based on the health information data and the physiological data; d) monitor the physiological data, during the exercise training of the patient to determine if the physiological data is within a predetermined range; and e) modify the exercise training plan for the patient if the physiological data is outside the predetermined range.
摘要翻译：提供了一种用于为患者提供运动训练计划的系统（200）。该系统包括传感器（202,204,206,208,210,212）和可操作地连接到该至少一个传感器的处理器（214）。传感器测量患者的生理参数。处理器被配置为：a）接收代表患者信息和患者症状的健康信息数据; b）从所述至少一个传感器接收生理数据; c）根据健康信息数据和生理数据设计患者的运动训练计划; d）在患者的运动训练期间监测生理数据，以确定生理数据是否在预定范围内; 以及e）如果生理数据在预定范围之外，则修改患者的运动训练计划。

5. 发明申请

US20130116807A1 BIOFEEDBACK FOR PROGRAM GUIDANCE IN PULMONARY REHABILITATION 有权
标题翻译：肺功能康复计划指南生物反馈
公开(公告)号：US20130116807A1
公开(公告)日：2013-05-09
申请号：US13518075
申请日：2010-11-17
申请人： Amy Oi Mee Cheung , Maryam Atakhorrami
发明人： Amy Oi Mee Cheung , Maryam Atakhorrami
IPC分类号： G06F17/40
CPC分类号： G06F17/40 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： A system (200) for providing an exercise training plan for a patient is provided. The system includes a sensor (202, 204, 206, 208, 210, 212), and a processor (214) operatively connected to the at least one sensor. The sensor measures physiological parameter of the patient. The processor is configured to: a) receive health information data representative of patient information and patient symptoms; b) receive physiological data from the at least one sensor; c) devise the exercise training plan for the patient based on the health information data and the physiological data; d) monitor the physiological data, during the exercise training of the patient to determine if the physiological data is within a predetermined range; and e) modify the exercise training plan for the patient if the physiological data is outside the predetermined range.
摘要翻译：提供了一种用于为患者提供运动训练计划的系统（200）。该系统包括传感器（202,204,206,208,210,212）和可操作地连接到该至少一个传感器的处理器（214）。传感器测量患者的生理参数。处理器被配置为：a）接收代表患者信息和患者症状的健康信息数据; b）从所述至少一个传感器接收生理数据; c）根据健康信息数据和生理数据设计患者的运动训练计划; d）在患者的运动训练期间监测生理数据，以确定生理数据是否在预定范围内; 以及e）如果生理数据在预定范围之外，则修改患者的运动训练计划。

6. 发明申请

US20130018595A1 COPD EXACERBATION DETECTION USING SPUTUM ANALYSIS 审中-公开
标题翻译：使用SPUTUM分析进行COPD检测
公开(公告)号：US20130018595A1
公开(公告)日：2013-01-17
申请号：US13638001
申请日：2011-02-24
申请人： Maryam Atakhorrami , Amy Oi Mee Cheung
发明人： Maryam Atakhorrami , Amy Oi Mee Cheung
IPC分类号： G01N33/487
CPC分类号： G01N33/487 , G01N2011/0026 , G01N2203/0075 , G01N2203/0089
摘要： Subject of the invention is the diagnosis and/or monitoring of chronic obstructive pulmonary disease based on sputum rheology. The complex modulus i.e. the viscous modulus and the elastic modulus of sputum is measured and assessed in respect of chronic obstructive pulmonary disease.
摘要翻译：本发明的主题是基于痰液流变学的慢性阻塞性肺疾病的诊断和/或监测。关于慢性阻塞性肺疾病，测量和评估复数模量，即粘性模量和痰弹性模量。

7. 发明申请

US20130102855A1 BODE INDEX MEASUREMENT 审中-公开
标题翻译：身体指数测量
公开(公告)号：US20130102855A1
公开(公告)日：2013-04-25
申请号：US13513007
申请日：2010-11-17
申请人： Amy Oi Mee Cheung , Maryam Atakhorrami
发明人： Amy Oi Mee Cheung , Maryam Atakhorrami
IPC分类号： A61B5/08 , A61B5/11 , A61B5/00
CPC分类号： A61B5/0826 , A61B5/0816 , A61B5/1118 , A61B5/4872 , A61B5/6804 , A61B5/6831 , A61B5/7225 , G16H50/20 , G16H50/30
摘要： A computer-implemented system and method for determining a BODE index value for a patient is provided. The method includes using a Body Mass Index (BMI) measuring device to obtain BMI data. An airway obstruction measuring device measures airway obstruction of the patient to obtain airway obstruction data. A respiration rate sensor measures a respiration rate of the patient and to obtain respiration rate data. An activity monitor measures physical activity of the patient and to obtain physical activity data. A processor executes a computer program module to determine the BODE index value for the patient based on the Body Mass Index data, the airway obstruction data, the respiration rate data, and the physical activity data.
摘要翻译：提供了一种用于确定患者的BODE指数值的计算机实现的系统和方法。该方法包括使用身体质量指数（BMI）测量装置获得BMI数据。气道阻塞测量装置测量患者的气道阻塞以获得气道阻塞数据。呼吸速率传感器测量患者的呼吸速率并获得呼吸速率数据。活动监测器测量患者的身体活动并获得身体活动数据。处理器执行计算机程序模块，以基于身体质量指数数据，气道阻塞数据，呼吸速率数据和身体活动数据来确定患者的BODE指数值。

8. 发明申请

US20130030258A1 COPD EXACERBATION PREDICTION SYSTEM AND METHOD 审中-公开
标题翻译： COPD预防系统和方法
公开(公告)号：US20130030258A1
公开(公告)日：2013-01-31
申请号：US13512962
申请日：2010-11-17
申请人： Amy Oi Mee Cheung , Maryam Atakhorrami , Geert Guy Georges Morren
发明人： Amy Oi Mee Cheung , Maryam Atakhorrami , Geert Guy Georges Morren
IPC分类号： A61B5/0205 , A61B5/11 , A61B5/08
CPC分类号： G06F19/3418 , G16H15/00 , G16H50/20
摘要： A computer-implemented method for predicting an onset of an exacerbation in a COPD patient is provided. The method includes measuring physical activity of the patient over a period of time to gather physical activity data; measuring a respiration characteristic of the patient over the period of time to gather respiration data; and executing, on one or more computer processors, one or more computer program modules to detect the onset of the exacerbation based on predetermined criteria, wherein the predetermined criteria comprises a comparison of a change in the respiration data with a change in the physical activity data.
摘要翻译：提供了一种用于预测COPD患者急性发作的计算机实现的方法。该方法包括测量患者在一段时间内的身体活动以收集身体活动数据; 测量患者在一段时间内的呼吸特征以收集呼吸数据; 以及在一个或多个计算机处理器上执行一个或多个计算机程序模块，以基于预定标准来检测所述恶化的开始，其中所述预定标准包括呼吸数据的变化与所述体力活动数据的变化的比较。

9. 发明申请

US20120330114A1 SYSTEM AND METHOD FOR OBTAINING AN OBJECTIVE MEASURE OF DYSPNEA 有权
标题翻译：用于获得DYSPNEA目标测量的系统和方法
公开(公告)号：US20120330114A1
公开(公告)日：2012-12-27
申请号：US13583072
申请日：2011-02-14
申请人： Amy Oi Mee Cheung , Maryam Atakhorrami
发明人： Amy Oi Mee Cheung , Maryam Atakhorrami
IPC分类号： A61B5/08 , A61B5/113 , A61B7/00 , A61B5/11
CPC分类号： G16H15/00 , A61B5/0816 , A61B5/1118 , A61B5/1135 , A61B5/6804 , A61B5/681 , A61B5/6824 , A61B5/6831 , A61B7/003 , G06F19/00 , G16H10/20 , G16H50/20
摘要： A computer-implemented method for assessing a level of dyspnea in a patient is provided. The method includes measuring physical activity of the patient over a period of time with an activity monitor to gather physical activity data; measuring respiration rate of the patient over the period of time with a respiration rate sensor to gather respiration rate data; administering a questionnaire to gather clinical information of the patient; and executing, on one or more computer processors, one or more computer program modules to determine a dyspnea value for the patient based on the respiration rate data, the physical activity data, and the clinical information of the patient. The dyspnea value is representative of the level of dyspnea in the patient.
摘要翻译：提供了一种用于评估患者呼吸困难水平的计算机实现的方法。该方法包括：通过活动监视器来测量患者在一段时间内的身体活动以收集身体活动数据; 用呼吸速率传感器测量患者在一段时间内的呼吸频率，以收集呼吸率数据; 管理问卷以收集病人的临床资料; 以及在一个或多个计算机处理器上执行一个或多个计算机程序模块，以基于呼吸速率数据，身体活动数据和患者的临床信息来确定患者的呼吸困难值。呼吸困难值代表患者呼吸困难程度。

10. 发明授权

US08945020B2 Zero heat flux sensor and method of use 有权
标题翻译：零热通量传感器及使用方法
公开(公告)号：US08945020B2
公开(公告)日：2015-02-03
申请号：US13144701
申请日：2009-12-23
申请人： Amy Oi Mee Cheung , Jasper Klewer
发明人： Amy Oi Mee Cheung , Jasper Klewer
IPC分类号： A61B5/00 , G01K1/14 , G01K1/16 , G01K7/21 , G01K13/00
CPC分类号： G01K1/14 , G01K1/16 , G01K1/165 , G01K7/21 , G01K13/002
摘要： When measuring core body temperature in a patient, a curved sensor (10) is provide that has a predefined radius of curvature to fit comfortably and closely to a patient's forehead. The sensor (10) has at least one releasable securing strip (e.g., Velcro™) that couples the sensor (10) to a headband (14), as well as an adhesive strip (16) that is positioned along one edge of an interior surface of the sensor (10) and couples the sensor (10) to the patient's skin. The adhesive strip acts as a hinge that facilitates inspection of the skin beneath the sensor without complete removal of the sensor, and the headband and curvature of the sensor provide a snug fit of the interior surface of the sensor against the patient's skin. Additionally, the sensor may be a zero heat flux sensor (34) with a heater (32) placed on one side thereof and a thermister (36) placed on an opposite side thereof, between the heat flux sensor (34) and a patient's skin. The heater is adjusted until heat flux through the heat flux sensor is zero, at which point the patient's skin surface temperature (as detected by the thermistor) is recorded as a core body temperature. Moreover, the thermister (34, 72) may be quickly calibrated by linearizing a temperature vs. resistance curve therefore, and shifting the linearized curve to a predetermined 15 reference curve.
摘要翻译：当测量患者体内的体温时，提供弯曲的传感器（10），其具有预定的曲率半径以适合和紧密地配合患者的前额。传感器（10）具有将传感器（10）连接到头带（14）的至少一个可释放的固定条（例如，Velcro TM）以及沿内部的一个边缘定位的粘合带（16）传感器（10）的表面并将传感器（10）耦合到患者的皮肤上。粘合带作为铰链，其有助于检查传感器下方的皮肤，而不会完全移除传感器，并且传感器的头带和曲率提供传感器内表面贴合患者皮肤的贴合配合。另外，传感器可以是零热通量传感器（34），其一侧放置有加热器（32），并且在热通量传感器（34）和患者皮肤之间放置热敏电阻（36）。调节加热器，直到通过热通量传感器的热通量为零，此时患者的皮肤表面温度（由热敏电阻检测）记录为核心体温。此外，可以通过线性化温度与电阻曲线来快速校准热敏电阻（34,72），并将线性化曲线移动到预定的15个参考曲线。

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