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1. 发明授权

US06866674B2 Medical grafting methods and apparatus 有权
标题翻译：医疗移植方法和装置
公开(公告)号：US06866674B2
公开(公告)日：2005-03-15
申请号：US10084010
申请日：2002-02-27
申请人： Jason A. Galdonik , William J. Swanson , Paul J. Hindrichs , Gregory A. Boldenow , Todd A. Berg , Rick Cornelius , Luis Bonilla
发明人： Jason A. Galdonik , William J. Swanson , Paul J. Hindrichs , Gregory A. Boldenow , Todd A. Berg , Rick Cornelius , Luis Bonilla
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/115 , A61B17/04
CPC分类号： A61B17/115 , A61B17/0644 , A61B17/11 , A61B46/17 , A61B2017/00557 , A61B2017/0641 , A61B2090/0801
摘要： Methods and apparatus for making an anastomotic connection between a first conduit and a second conduit. A connector structure having a first end portion and a second end portion is positioned about a balloon catheter, which when pressurized, expands to a significant extent at the distal end thereof. The balloon enlarges the connector structure when positioned at the distal end portion of the balloon to create the anastomosis, and at the same time reduces the axial length of the connector, thereby compressing the first conduit to the second conduit, creating a hemodynamic seal and a firm attachment of the two conduits. After enlargement, the connector structure remains in place and adds structure to the anastomosis. During introduction, the second end portion of the connector is covered by a nosecone assembly to prevent trauma to the second conduit while the apparatus is being introduced. The nosecone assembly has a flexible structure which may change configuration to expose the second set of members after insertion into the second conduit and to allow removal of the nosecone after deployment.
摘要翻译：用于在第一导管和第二导管之间进行吻合连接的方法和装置。具有第一端部部分和第二端部部分的连接器结构围绕球囊导管定位，当加压时，其在其远端处显着扩张。当定位在球囊的远端部分时，气囊扩大连接器结构以产生吻合，并且同时减小连接器的轴向长度，从而将第一导管压缩到第二导管，产生血流动力学密封和坚固的连接两个管道。放大后，连接器结构保持原位，并将结构添加到吻合中。在引入期间，连接器的第二端部被鼻锥组件覆盖，以在装置被引入时防止对第二导管的创伤。鼻锥组件具有柔性结构，其可以改变配置以在插入第二导管之后暴露第二组构件，并且在展开之后允许去除鼻锥。

2. 发明授权

US06602263B1 Medical grafting methods and apparatus 有权
公开(公告)号：US06602263B1
公开(公告)日：2003-08-05
申请号：US09693578
申请日：2000-10-20
申请人： William J. Swanson , Jason A. Galdonik , Paul J. Hindrichs , Gregory A. Boldenow , Todd A. Berg , Rick Cornelius , Luis Bonilla
发明人： William J. Swanson , Jason A. Galdonik , Paul J. Hindrichs , Gregory A. Boldenow , Todd A. Berg , Rick Cornelius , Luis Bonilla
IPC分类号： A61B1712
CPC分类号： A61B17/115 , A61B17/0644 , A61B17/11 , A61B46/17 , A61B2017/00557 , A61B2017/0641 , A61B2090/0801
摘要： Methods and apparatus for making an anastomotic connection between a first conduit and a second conduit. A connector structure having a first end portion and a second end portion is positioned about a balloon catheter, which when pressurized, expands to a significant extent at the distal end thereof. The balloon enlarges the connector structure when positioned at the distal end portion of the balloon to create the anastomosis, and at the same time reduces the axial length of the connector, thereby compressing the first conduit to the second conduit, creating a hemodynamic seal and a firm attachment of the two conduits. After enlargement, the connector structure remains in place and adds structure to the anastomosis. During introduction, the second end portion of the connector is covered by a nosecone assembly to prevent trauma to the second conduit while the apparatus is being introduced. The nosecone assembly has a flexible structure which may change configuration to expose the second set of members after insertion into the second conduit and to allow removal of the nosecone after deployment.

3. 发明授权

US06712836B1 Apparatus and methods for closing septal defects and occluding blood flow 有权
标题翻译：用于闭合间隔缺损并阻塞血流的装置和方法
公开(公告)号：US06712836B1
公开(公告)日：2004-03-30
申请号：US09570358
申请日：2000-05-12
申请人： Todd A. Berg , Alex A. Peterson , William J. Swanson , Paul J. Hindrichs
发明人： Todd A. Berg , Alex A. Peterson , William J. Swanson , Paul J. Hindrichs
IPC分类号： A61B1704
CPC分类号： A61B17/0057 , A61B90/39 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2090/3941
摘要： Plugs and methods for plugging septal defects and blood vessels are provided. Plugs are delivered via catheter to a septal defect or a location where it is desired to occlude blood flow in a blood vessel. The plugs are positioned and expanded at the treatment site. The expansion of the plugs can be accomplished passively by using a heat-treated elastic frame or actively by using a balloon to deform a plastically-deforming frame. Plugging structures mounted to the frame span the defect or lumen and prevent blood flow. The plugs described herein have small profiles, and are more reliable than preceding intraluminal transcatheter methods.
摘要翻译：提供了堵塞间隔缺损和血管的插塞和方法。插头通过导管输送到隔膜缺损或希望阻塞血管中的血液流动的位置。栓塞在治疗部位定位和扩张。插塞的膨胀可以通过使用经热处理的弹性框架被动地完成，或者主动地通过使用气球来使塑性变形框架变形。安装在框架上的堵塞结构跨越缺陷或内腔，防止血液流动。本文所述的塞子具有小的轮廓，并且比先前的腔内经导管方法更可靠。

4. 发明授权

US06212422B1 Catheter having a high tensile strength braid wire constraint and method of manufacture 有权
标题翻译：导管具有高拉伸强度编织线约束和制造方法
公开(公告)号：US06212422B1
公开(公告)日：2001-04-03
申请号：US09346973
申请日：1999-07-02
申请人： Todd A. Berg , Jason A. Galdonik , Henry Pepin , Brian Scovil
发明人： Todd A. Berg , Jason A. Galdonik , Henry Pepin , Brian Scovil
IPC分类号： A61B500
CPC分类号： A61M25/0012 , A61M25/0009 , A61M25/0015 , A61M25/005 , A61M39/10 , Y10T428/2935 , Y10T428/294
摘要： A tubing assembly for manufacture for a catheter of the type having an inner tubular member defining a lumen, an outer tubular member surrounding said inner member, and a support member mounted between the tubular members to provide rigidity to the flexible catheter. The support member comprises a high tensile strength wire braid, and in the preferred embodiment comprises a stainless steel wire braid which has been tempered or hardened. This higher tensile strength affords significantly greater kink resistance to the flexible catheter. One wire braid has a tensile strength in the range of 300 to 425 kpsi and a braid density of approximately 40 pic. The high tensile strength wire braid has the disadvantage of tending to flare out at its free ends. Therefore, means are provided for preventing the flaring of the wire braid during manufacture of the tubing assembly. One means includes adhesive applied over the free ends. Another means includes a restraining sleeve applied over the free ends.
摘要翻译：一种用于制造导管的管组件，其具有限定内腔的内部管状构件，围绕所述内部构件的外部管状构件和安装在管状构件之间的支撑构件，以向柔性导管提供刚性。支撑构件包括高抗拉强度的线编织物，并且在优选实施例中包括已经回火或硬化的不锈钢丝编织物。这种较高的拉伸强度使柔性导管具有显着更大的扭结抗性。一根丝编织物的拉伸强度范围为300至425kpsi，编织密度约为40pi。高抗拉强度丝编织物的缺点在于它的自由端有倾向。因此，提供了用于在制造管组件期间防止线编织物的扩口的装置。一种方法包括在自由端施加的粘合剂。另一种装置包括施加在自由端上的限制套筒。

5. 发明授权

US07297302B2 Catheter having a high tensile strength braid wire constraint and method of manufacture 有权
标题翻译：导管具有高拉伸强度编织线约束和制造方法
公开(公告)号：US07297302B2
公开(公告)日：2007-11-20
申请号：US10310016
申请日：2002-12-04
申请人： Todd A. Berg , Jason A. Galdonik , Henry Pepin , Brian Scovil
发明人： Todd A. Berg , Jason A. Galdonik , Henry Pepin , Brian Scovil
IPC分类号： B29C59/00
CPC分类号： A61M25/0012 , A61M25/0009 , A61M25/0015 , A61M25/005 , A61M39/10 , Y10T428/2935 , Y10T428/294
摘要： A tubing assembly for manufacture for a catheter of the type having an inner tubular member defining a lumen, an outer tubular member surrounding said inner member, and a support member mounted between the tubular members to provide rigidity to the flexible catheter. The support member comprises a high tensile strength wire braid, and in the preferred embodiment comprises a stainless steel wire braid which has been tempered or hardened. This higher tensile strength affords significantly greater kink resistance to the flexible catheter. One wire braid has a tensile strength in the range of 300 to 425 kpsi and a braid density of approximately 40 pic. The high tensile strength wire braid has the disadvantage of tending to flare out at its free ends. Therefore, means are provided for preventing the flaring of the wire braid during manufacture of the tubing assembly. One means includes adhesive applied over the free ends. Another means includes a restraining sleeve applied over the free ends.
摘要翻译：一种用于制造导管的管组件，其具有限定内腔的内部管状构件，围绕所述内部构件的外部管状构件和安装在管状构件之间的支撑构件，以向柔性导管提供刚性。支撑构件包括高抗拉强度的线编织物，并且在优选实施例中包括已经回火或硬化的不锈钢丝编织物。这种较高的拉伸强度使柔性导管具有显着更大的扭结抗性。一根丝编织物的拉伸强度范围为300至425kpsi，编织密度约为40pi。高抗拉强度丝编织物的缺点在于它的自由端有倾向。因此，提供了用于在制造管组件期间防止线编织物的扩口的装置。一种方法包括在自由端施加的粘合剂。另一种装置包括施加在自由端上的限制套筒。

6. 发明授权

US06635022B2 Braidless guide catheter 有权
标题翻译：无引导导管
公开(公告)号：US06635022B2
公开(公告)日：2003-10-21
申请号：US09736560
申请日：2000-12-13
申请人： Todd A. Berg , Brian Scovil , Jason A. Galdonik , Thomas J. Bachinski
发明人： Todd A. Berg , Brian Scovil , Jason A. Galdonik , Thomas J. Bachinski
IPC分类号： A61B500
CPC分类号： A61M25/0662 , A61M25/09 , A61M2025/09083
摘要： Guide catheter incorporating a braidless construction having increased performance characteristics for catheterization procedures. The guide catheter may include a tracking wire, inner or outer guide for positioning the guide catheter within the patient's vascular system.
摘要翻译：引导导管包括具有增加的用于导管插入术的性能特征的无编织结构。引导导管可以包括跟踪线，用于将引导导管定位在患者的血管系统内的内部或外部引导件。

7. 发明授权

US5954651A Catheter having a high tensile strength braid wire constraint 失效
标题翻译：导管具有高抗拉强度编织线约束
公开(公告)号：US5954651A
公开(公告)日：1999-09-21
申请号：US936983
申请日：1997-09-25
申请人： Todd A. Berg , Jason A. Galdonik , Henry Pepin , Brian Scovil
发明人： Todd A. Berg , Jason A. Galdonik , Henry Pepin , Brian Scovil
IPC分类号： A61M25/00 , A61M25/16 , A61M39/10 , A61B5/00
CPC分类号： A61M25/0012 , A61M25/005 , A61M25/0009 , A61M25/0015 , A61M39/10 , Y10T428/2935 , Y10T428/294
摘要： A tubing assembly for manufacture for a catheter of the type having an inner tubular member defining a lumen, an outer tubular member surrounding said inner member, and a support member mounted between the tubular members to provide rigidity to the flexible catheter. The support member comprises a high tensile strength wire braid, and in the preferred embodiment comprises a stainless steel wire braid which has been tempered or hardened. This higher tensile strength affords significantly greater kink resistance to the flexible catheter. One wire braid has a tensile strength in the range of 300 to 425 kpsi and a braid density of approximately 40 pic. The high tensile strength wire braid has the disadvantage of tending to flare out at its free ends. Therefore, means are provided for preventing the flaring of the wire braid during manufacture of the tubing assembly. One means includes adhesive applied over the free ends. Another means includes a restraining sleeve applied over the free ends.
摘要翻译：一种用于制造导管的管组件，其具有限定内腔的内部管状构件，围绕所述内部构件的外部管状构件和安装在管状构件之间的支撑构件，以向柔性导管提供刚性。支撑构件包括高抗拉强度的线编织物，并且在优选实施例中包括已经回火或硬化的不锈钢丝编织物。这种较高的拉伸强度使柔性导管具有显着更大的扭结抗性。一根丝编织物的拉伸强度范围为300至425kpsi，编织密度约为40pi。高抗拉强度丝编织物的缺点在于它的自由端有倾向。因此，提供了用于在制造管组件期间防止线编织物的扩口的装置。一种方法包括在自由端施加的粘合剂。另一种装置包括施加在自由端上的限制套筒。

8. 发明授权

US5951495A Catheter having an adhesive braid wire constraint and method of manufacture 失效
标题翻译：导管具有粘合编织线约束和制造方法
公开(公告)号：US5951495A
公开(公告)日：1999-09-14
申请号：US800926
申请日：1997-02-13
申请人： Todd A. Berg , Jason A. Galdonik
发明人： Todd A. Berg , Jason A. Galdonik
IPC分类号： A61M25/00 , A61M25/16 , A61M39/10 , A61B5/00
CPC分类号： A61M25/005 , A61M25/0009 , A61M25/0012 , A61M39/10
摘要： A tubing assembly and method of manufacture for a catheter of the type having an inner tubular member defining a lumen, an outer tubular member surrounding said inner member, and a support member mounted between the tubular members to provide rigidity to the flexible catheter. The support member comprises a wire braid, and in the preferred embodiment comprises a stainless steel wire braid which has been tempered or hardened to give it a significantly high tensile strength. This higher tensile strength affords significantly greater kink resistance to the flexible catheter as the lumen size is increased and the wall thickness is decreased, however, the high tensile strength wire braid has the disadvantage of tending to flare out at its free ends. Therefore, means are provided for preventing the flaring of the wire braid during manufacture of the tubing assembly.
摘要翻译：一种用于导管的管组件和制造方法，其具有限定内腔的内部管状构件，围绕所述内部构件的外部管状构件和安装在管状构件之间的支撑构件，以向柔性导管提供刚性。支撑构件包括线编织物，并且在优选实施例中包括不锈钢丝编织物，其已被回火或硬化以赋予其显着高的拉伸强度。随着管腔尺寸的增加和壁厚的减小，这种较高的拉伸强度提供了对柔性导管的显着更大的扭结阻力，然而，高抗拉强度的丝编织物的缺点是趋向于在其自由端上展开。因此，提供了用于在制造管组件期间防止线编织物的扩口的装置。

9. 发明授权

US5911715A Guide catheter having selected flexural modulus segments 失效
标题翻译：导管具有选定的弯曲模数段
公开(公告)号：US5911715A
公开(公告)日：1999-06-15
申请号：US800927
申请日：1997-02-13
申请人： Todd A. Berg , Jason A. Galdonik
发明人： Todd A. Berg , Jason A. Galdonik
IPC分类号： A61L29/00 , A61M25/00 , A61M25/088 , A61M25/16 , F16L9/147 , F16L11/08
CPC分类号： A61M25/0009 , A61M25/0043 , A61M25/0054 , F16L11/081 , F16L9/147 , A61M2025/006 , A61M2025/0098 , A61M25/0021 , A61M25/0045 , A61M25/005 , A61M25/0051 , A61M25/0053
摘要： A guiding catheter for use in coronary angioplasty and other cardiovascular interventions which incorporates a plurality of segment of selected flexural modulus in the shaft of the device. The segments which have a different flexibility than the sections immediately proximal and distal to them, creating zones in the catheter shaft which are either more or less flexible than other zones of the shaft. The flexibility and length of the shaft in a given zone is then matched to its clinical function and role. A mid-shaft zone is significantly softer than a proximal shaft or distal secondary curve to better traverse the aortic arch shape without storing too much energy. A secondary zone section is designed to have maximum stiffness to provide optimum backup support and stability.
摘要翻译：用于冠状动脉血管成形术和其他心血管干预的引导导管，其在装置的轴中并入多个选定的弯曲模量段。这些段具有与紧邻的部分不同的部分，在导管轴中产生与轴的其它区域或多或少柔性的区域。然后在给定区域中的轴的柔性和长度与其临床功能和作用相匹配。中轴区域比近侧轴或远端二级曲线显着更软，以更好地横穿主动脉弓形状而不存储太多的能量。次级区域设计为具有最大刚度以提供最佳的后备支撑和稳定性。

10. 发明授权

US5897537A Guide catheter having a plurality of filled distal grooves 失效
标题翻译：引导导管具有多个填充的远端凹槽
公开(公告)号：US5897537A
公开(公告)日：1999-04-27
申请号：US703635
申请日：1996-08-27
申请人： Todd A. Berg , Brian J. Scovil , Jason A. Galdonik
发明人： Todd A. Berg , Brian J. Scovil , Jason A. Galdonik
IPC分类号： A61M25/00 , A61M25/088 , F16L9/147 , F16L11/08
CPC分类号： F16L11/081 , A61M25/0009 , A61M25/0043 , A61M25/0054 , F16L9/147 , A61M2025/006 , A61M2025/0098 , A61M25/0021 , A61M25/0045 , A61M25/005 , A61M25/0051 , A61M25/0053
摘要： A guiding catheter for use in coronary angioplasty and other cardiovascular interventions which incorporates a transition element in the shaft of the device. The transition element which has a different flexibility than the sections immediately proximal and distal to it, creates a zone in the catheter shaft which is either more or less flexible than the rest of the shaft. The transition element allows a portion of the shaft to be made more rigid or more flexible, without changing the flexibility of the other portions of the shaft. The transition element also allows for a differential flexibility to be added to the catheter shaft.
摘要翻译：用于冠状动脉血管成形术和其他心血管干预的引导导管，其在装置的轴中结合有过渡元件。过渡元件具有不同于紧邻其近端和远端的部分的柔性，导致导管轴中的区域或多或少地比轴的其余部分柔性。过渡元件允许轴的一部分制成更刚性或更柔性，而不改变轴的其它部分的柔性。过渡元件还允许将不同的灵活性添加到导管轴。

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