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1. 发明授权

US08893669B2 Hybrid cooling system of an internal combustion engine 有权
标题翻译：内燃机混合冷却系统
公开(公告)号：US08893669B2
公开(公告)日：2014-11-25
申请号：US13278941
申请日：2011-10-21
申请人： Jan Mehring , Bernd Steiner , Carsten Weber
发明人： Jan Mehring , Bernd Steiner , Carsten Weber
IPC分类号： F01P7/00 , F01P3/02 , F01M1/12 , F01P3/00
CPC分类号： F01P3/02 , F01M2001/123 , F01P2003/008 , F01P2003/021 , F01P2003/024 , F01P2037/02
摘要： A hybrid cooling system for an engine is provided. The system comprises a block oil cooling circuit, a head coolant cooling circuit, the head and block circuits having a common heat exchanger. The system also includes a flow device in the head cooling circuit for preventing coolant flow in the head cooling circuit at least during a first phase of a warm-up phase of the internal combustion engine, a delivery device in the block cooling circuit which delivers engine oil constantly under pressure through the block cooling circuit to bearing points in a cylinder block and to bearing points in a cylinder head, and a control element arranged in a control line to reduce the delivery capacity of the delivery device through the block cooling circuit at least during the first phase of the warm-up phase. In this way, heat transfer in the common heat exchanger may be substantially prevented.
摘要翻译：提供了一种用于发动机的混合冷却系统。该系统包括块油冷却回路，头部冷却剂冷却回路，头部和块状回路具有共同的热交换器。该系统还包括头部冷却回路中的流动装置，用于至少在内燃机的预热阶段的第一阶段期间防止冷却剂在头部冷却回路中的流动;块冷却回路中的输送装置，其输送发动机在压力下通过块体冷却回路将油保持在气缸体中的轴承点和气缸盖中的轴承点，以及布置在控制线中的控制元件，以至少通过块冷却回路减少输送装置的输送能力在预热阶段的第一阶段。以这种方式，可以基本上防止公共热交换器中的热传递。

2. 发明授权

US08621865B2 Internal combustion engine with liquid-cooled turbine 有权
标题翻译：内燃机采用液冷式涡轮机
公开(公告)号：US08621865B2
公开(公告)日：2014-01-07
申请号：US13253817
申请日：2011-10-05
申请人： Jan Mehring , Ludwig Stump , Kai Sebastian Kuhlbach , Bernd Steiner , Carsten Weber , Franz J. Brinkmann , Frank Kraemer , Jens Groeger
发明人： Jan Mehring , Ludwig Stump , Kai Sebastian Kuhlbach , Bernd Steiner , Carsten Weber , Franz J. Brinkmann , Frank Kraemer , Jens Groeger
IPC分类号： F02B33/44
CPC分类号： F01P3/02 , F01D25/14 , F01P3/12 , F01P7/165 , F01P2003/008 , F01P2003/024 , F01P2060/12 , F02F1/243 , F05D2220/40 , F05D2260/232
摘要： Embodiments for cooling a turbine of an engine are provided. In one example embodiment, an internal combustion engine comprises a turbocharger including a turbine having a coolant jacket integrated in a housing of the turbine, and an oil circuit coupled to the coolant jacket of the turbine. By cooling the turbine with the oil circuit, the turbine may be constructed from less-heat resistant materials.
摘要翻译：提供了用于冷却发动机的涡轮机的实施例。在一个示例性实施例中，内燃机包括涡轮增压器，涡轮增压器包括具有集成在涡轮机壳体中的冷却剂护套的涡轮机，以及联接到涡轮机的冷却剂护套的油回路。通过用油回路冷却涡轮机，涡轮机可以由耐热材料构成。

3. 发明申请

US20120067306A1 INTERNAL COMBUSTION ENGINE WITH LIQUID-COOLED TURBINE 有权
标题翻译：具有液体冷却涡轮的内燃机
公开(公告)号：US20120067306A1
公开(公告)日：2012-03-22
申请号：US13253817
申请日：2011-10-05
申请人： Jan Mehring , Ludwig Stump , Kai Sebastian Kuhlbach , Bernd Steiner , Carsten Weber , Franz J. Brinkmann , Frank Kraemer , Jens Groeger
发明人： Jan Mehring , Ludwig Stump , Kai Sebastian Kuhlbach , Bernd Steiner , Carsten Weber , Franz J. Brinkmann , Frank Kraemer , Jens Groeger
IPC分类号： F02F1/10
CPC分类号： F01P3/02 , F01D25/14 , F01P3/12 , F01P7/165 , F01P2003/008 , F01P2003/024 , F01P2060/12 , F02F1/243 , F05D2220/40 , F05D2260/232
摘要： Embodiments for cooling a turbine of an engine are provided. In one example embodiment, an internal combustion engine comprises a turbocharger including a turbine having a coolant jacket integrated in a housing of the turbine, and an oil circuit coupled to the coolant jacket of the turbine. By cooling the turbine with the oil circuit, the turbine may be constructed from less-heat resistant materials.
摘要翻译：提供了用于冷却发动机的涡轮机的实施例。在一个示例性实施例中，内燃机包括涡轮增压器，涡轮增压器包括具有集成在涡轮机壳体中的冷却剂护套的涡轮机，以及联接到涡轮机的冷却剂护套的油回路。通过用油回路冷却涡轮机，涡轮机可以由耐热材料构成。

4. 发明申请

US20120118248A1 HYBRID COOLING SYSTEM OF AN INTERNAL COMBUSTION ENGINE 有权
标题翻译：内燃机混合冷却系统
公开(公告)号：US20120118248A1
公开(公告)日：2012-05-17
申请号：US13278941
申请日：2011-10-21
申请人： Jan Mehring , Bernd Steiner , Carsten Weber
发明人： Jan Mehring , Bernd Steiner , Carsten Weber
IPC分类号： F01P7/00
CPC分类号： F01P3/02 , F01M2001/123 , F01P2003/008 , F01P2003/021 , F01P2003/024 , F01P2037/02
摘要： A hybrid cooling system for an engine is provided. The system comprises a block oil cooling circuit, a head coolant cooling circuit, the head and block circuits having a common heat exchanger. The system also includes a flow device in the head cooling circuit for preventing coolant flow in the head cooling circuit at least during a first phase of a warm-up phase of the internal combustion engine, a delivery device in the block cooling circuit which delivers engine oil constantly under pressure through the block cooling circuit to bearing points in a cylinder block and to bearing points in a cylinder head, and a control element arranged in a control line to reduce the delivery capacity of the delivery device through the block cooling circuit at least during the first phase of the warm-up phase. In this way, heat transfer in the common heat exchanger may be substantially prevented.
摘要翻译：提供了一种用于发动机的混合冷却系统。该系统包括块油冷却回路，头部冷却剂冷却回路，头部和块状回路具有共同的热交换器。该系统还包括头部冷却回路中的流动装置，用于至少在内燃机的预热阶段的第一阶段期间防止冷却剂在头部冷却回路中的流动;块冷却回路中的输送装置，其输送发动机在压力下通过块体冷却回路将油保持在气缸体中的轴承点和气缸盖中的轴承点，以及布置在控制线中的控制元件，以至少通过块冷却回路减少输送装置的输送能力在预热阶段的第一阶段。以这种方式，可以基本上防止公共热交换器中的热传递。

5. 发明申请

US20080168956A1 Integrated Engine Thermal Management 有权
标题翻译：集成发动机热管理
公开(公告)号：US20080168956A1
公开(公告)日：2008-07-17
申请号：US12015743
申请日：2008-01-17
申请人： Martin Lutz , Carsten Weber , Jan Mehring , Ingo Lenz , Kai Sebastian Kuhlbach , Richard Fritsche
发明人： Martin Lutz , Carsten Weber , Jan Mehring , Ingo Lenz , Kai Sebastian Kuhlbach , Richard Fritsche
IPC分类号： F01P7/16
CPC分类号： F01P7/165 , F01P3/02 , F01P2003/024 , F01P2003/027 , F01P2037/02 , F01P2060/16
摘要： The invention relates to a cooling strategy for an internal combustion engine (1) which has at least one cylinder head (2) and an associated cylinder block (3). A coolant flows in a coolant circuit (4), with at least one control element (6, 7, 8, 9) being assigned to the coolant circuit (4). During a warmup of the internal combustion engine, in successive phases, the coolant flow is conducted to separate cooling regions by the control elements (6, 7, 8, 9), wherein in an operating mode at operating temperature which follows the warmup, the coolant flow is conducted to separate cooling regions by the control elements (6, 7, 8, 9) taking into consideration the operating states of the internal combustion engine.
摘要翻译：本发明涉及一种具有至少一个气缸盖（2）和相关气缸体（3）的内燃机（1）的冷却策略。冷却剂流入冷却剂回路（4），其中至少一个控制元件（6,7,8,9）被分配给冷却剂回路（4）。在内燃机的预热期间，在连续的阶段中，冷却剂流被传导以通过控制元件（6,7,8,9）分离冷却区域，其中在运行温度下，在加热之后的操作模式中，考虑到内燃机的运行状态，通过控制元件（6,7,8,9）分离冷却剂流以分离冷却区域。

6. 发明授权

US07721683B2 Integrated engine thermal management 有权
标题翻译：集成发动机热管理
公开(公告)号：US07721683B2
公开(公告)日：2010-05-25
申请号：US12015743
申请日：2008-01-17
申请人： Martin Lutz , Carsten Weber , Jan Mehring , Ingo Lenz , Kai Sebastian Kuhlbach , Richard Fritsche
发明人： Martin Lutz , Carsten Weber , Jan Mehring , Ingo Lenz , Kai Sebastian Kuhlbach , Richard Fritsche
IPC分类号： F01P7/14
CPC分类号： F01P7/165 , F01P3/02 , F01P2003/024 , F01P2003/027 , F01P2037/02 , F01P2060/16
摘要： The invention relates to a cooling strategy for an internal combustion engine (1) which has at least one cylinder head (2) and an associated cylinder block (3). A coolant flows in a coolant circuit (4), with at least one control element (6, 7, 8, 9) being assigned to the coolant circuit (4). During a warmup of the internal combustion engine, in successive phases, the coolant flow is conducted to separate cooling regions by the control elements (6, 7, 8, 9), wherein in an operating mode at operating temperature which follows the warmup, the coolant flow is conducted to separate cooling regions by the control elements (6, 7, 8, 9) taking into consideration the operating states of the internal combustion engine.
摘要翻译：本发明涉及一种具有至少一个气缸盖（2）和相关气缸体（3）的内燃机（1）的冷却策略。冷却剂流入冷却剂回路（4），其中至少一个控制元件（6,7,8,9）被分配给冷却剂回路（4）。在内燃机的预热期间，在连续的阶段中，冷却剂流被传导以通过控制元件（6,7,8,9）分离冷却区域，其中在运行温度下，在加热之后的操作模式中，考虑到内燃机的运行状态，通过控制元件（6,7,8,9）分离冷却剂流以分离冷却区域。

7. 发明授权

US09315255B2 Aircraft comprising a device for influencing the directional stability of the aircraft, and a method for influencing the directional stability of the aircraft 有权
标题翻译：包括用于影响飞行器的方向稳定性的装置的飞行器以及影响飞行器的方向稳定性的方法
公开(公告)号：US09315255B2
公开(公告)日：2016-04-19
申请号：US13255246
申请日：2010-03-17
申请人： Carsten Weber , Markus Fischer , Arnaud Namer
发明人： Carsten Weber , Markus Fischer , Arnaud Namer
IPC分类号： B64C5/06 , B64C9/32
CPC分类号： B64C5/06 , B64C9/32 , Y02T50/32
摘要： An aircraft including a device for influencing the directional stability of the aircraft is provided. The device includes a control-input device; a flight control device; a sensor device for acquiring the rotation rates, including the yaw rates, of the aircraft; and at least one actuator, which is coupled with ailerons, spoilers, an elevator and a rudder. The flight control device includes a control function generating adjusting commands for the actuators for controlling the aircraft according to control commands. The aircraft includes two tail-mounted flaps, each including an actuator connected with the flight control device, situated symmetrically to each other and on opposite sides of the fuselage, and movable between retracted and extended positions. The control function is designed such that the adjusting commands that are generated on the basis of the control commands depending on the acquired rotation rates include adjusting commands to the actuators of the tail-mounted flaps.
摘要翻译：提供了包括用于影响飞行器的方向稳定性的装置的飞机。该装置包括控制输入装置; 飞行控制装置; 用于获取飞行器的转速的传感器装置，包括偏航率; 以及与副翼，扰流器，电梯和方向舵耦合的至少一个致动器。飞行控制装置包括控制功能，该控制功能根据控制命令产生用于控制飞行器的致动器的调节命令。飞机包括两个尾部安装的翼片，每个翼片包括与飞行控制装置连接的致动器，其彼此对称并且在机身的相对侧上对准，并且可在缩回位置和伸出位置之间移动。控制功能被设计成使得基于所获取的旋转速度而基于控制命令生成的调节命令包括调整到尾部安装的翼片的致动器的命令。

8. 发明授权

US08821865B2 High concentration anti-TNFα antibody liquid formulations 有权
标题翻译：高浓度抗TNFα抗体液体制剂
公开(公告)号：US08821865B2
公开(公告)日：2014-09-02
申请号：US13294692
申请日：2011-11-11
申请人： Michael Neu , Markus Tschoepe , Carsten Weber , Wolfgang Fraunhofer , Laura Redden , Martin Gastens , Alexander Feick
发明人： Michael Neu , Markus Tschoepe , Carsten Weber , Wolfgang Fraunhofer , Laura Redden , Martin Gastens , Alexander Feick
IPC分类号： A61K39/395 , C07K16/24 , A61K39/00
CPC分类号： C07K16/241 , A61K9/0019 , A61K39/39591 , A61K47/26 , A61K2039/505 , C07K2317/21 , C07K2317/565 , C07K2317/76 , C07K2317/90 , C07K2317/94 , Y02A50/412
摘要： The invention provides a liquid aqueous pharmaceutical formulation comprising a human anti-TNFa antibody, or antigen-binding portion thereof, which reduces pain associated with injection in a subject by at least about 50% when compared to injecting an otherwise identical formulation comprising at least one salt and/or at least one buffer. The invention also provides a liquid aqueous pharmaceutical formulation comprising a human anti-TNFa antibody, or antigen-binding portion thereof, having increased bioavailability upon subcutaneous administration into a subject. The formulation may comprise a therapeutic protein, such as a human anti-TNF-alpha antibody, or an antigen-binding portion thereof, or a biosimilar thereof.
摘要翻译：本发明提供了包含人抗TNFα抗体或其抗原结合部分的液体水性药物制剂，当与注射包含至少一种抗体的相同的制剂相比时，将与受试者中注射相关的疼痛降低至少约50％盐和/或至少一种缓冲液。本发明还提供了包含人抗TNFα抗体或其抗原结合部分的液体水性药物制剂，其在皮下施用于受试者时具有增加的生物利用度。制剂可以包含治疗性蛋白质，例如人抗TNF-α抗体或其抗原结合部分，或其生物相似物。

9. 发明授权

US08607639B2 Method and device for determining mechanical stress load and interface effects on particles dispersed in a fluid 有权
标题翻译：用于确定分散在流体中的颗粒的机械应力负荷和界面效应的方法和装置
公开(公告)号：US08607639B2
公开(公告)日：2013-12-17
申请号：US13049362
申请日：2011-03-16
申请人： Hans-Jürgen Krause , Carsten Weber , Sonja Simon , Wolfgang Peukert
发明人： Hans-Jürgen Krause , Carsten Weber , Sonja Simon , Wolfgang Peukert
IPC分类号： G01N3/00
CPC分类号： G01N1/286 , G01N11/04 , G01N33/487
摘要： The present invention concerns a method and a device for determining mechanical stress load, and optionally interface effects, on particles dispersed in a fluid. According to the invention, fluid comprising dispersed particles such as biomolecules is fed into a sample space of a device comprising a jacket which encloses a sample chamber and at least two rolls arranged within said jacket such that said sample space is defined between said rolls, said rolls being independently rotatable with respect to each other, wherein said jacket has an inner surface which is essentially adapted to the outer surface of the rolls, rotational movement is imparted to at least one of the rolls of said device, and changes in the state of said particles are determined from which mechanical stress load acting on the particles can be determined.
摘要翻译：本发明涉及一种用于确定分散在流体中的颗粒的机械应力负荷和任选的界面效应的方法和装置。根据本发明，包含分散颗粒如生物分子的流体被送入装置的样品空间中，所述装置包括封套样品室的外套和布置在所述夹套内的至少两个辊，使得所述样品空间限定在所述辊之间，所述辊可以相对于彼此独立地旋转，其中所述护套具有基本适合于辊的外表面的内表面，旋转运动被赋予所述装置的至少一个辊，并且转动状态的变化从确定作用在颗粒上的机械应力载荷确定所述颗粒。

10. 发明申请

US20120205490A1 AIRCRAFT HORIZONTAL STABILISER FITTED WITH LEADING-EDGE STRAKE 审中-公开
标题翻译：飞机水平稳定器配有前沿边缘
公开(公告)号：US20120205490A1
公开(公告)日：2012-08-16
申请号：US13502175
申请日：2010-10-18
申请人： Ian Roy Whitehouse , Carsten Weber , Markus Fischer , Alain Tanguy
发明人： Ian Roy Whitehouse , Carsten Weber , Markus Fischer , Alain Tanguy
IPC分类号： B64C5/02 , B64C5/06
CPC分类号： B64C5/02 , B64C23/06 , Y02T50/162
摘要： An adjustable, or all-moving, horizontal stabiliser for an aircraft, the stabiliser having a leading edge, a trailing edge, a root and a tip, and a strake fixed with respect to the stabiliser and attached to, or integrally formed with, the stabiliser leading edge adjacent the root.
摘要翻译：一种用于飞行器的可调节或全移动的水平稳定器，所述稳定器具有前缘，后缘，根部和尖端以及相对于所述稳定器固定或与所述稳定器一体形成的支架稳定器前缘毗邻根部。

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