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1. 发明授权

US06426315B1 Process for introducing a functionality 有权
标题翻译：介绍功能的过程
公开(公告)号：US06426315B1
公开(公告)日：2002-07-30
申请号：US09380105
申请日：2000-03-14
申请人： Jan Bergstrom , Rolf Berglund , Lennart Soderberg
发明人： Jan Bergstrom , Rolf Berglund , Lennart Soderberg
IPC分类号： B01J3100
CPC分类号： C08B37/0039 , B01J20/3212 , B01J20/3234 , C08B37/0021
摘要： Process for, in layers of a porous matrix, exhibiting the groups A, introducing a functionality using a reagent I, introducing the functionality by a reaction with the groups A. The characterizing feature is that the matrix is contacted with a functional deficiency of reagent I and that conditions and reagent I are chosen so that the reaction between reagent I and the groups A is more rapid than diffusion of reagent I in the matrix.
摘要翻译：在多孔基质的层中，显示基团A的方法，使用试剂I引入官能团，通过与基团A的反应引入官能团。表征特征是基质与试剂I的功能缺陷接触并且选择条件和试剂I，使得试剂I和A组之间的反应比试剂I在基质中的扩散更快。

2. 发明授权

US6090288A Process for chromatographic separation of peptides and nucleic acid, and new high affinity ion exchange matrix 有权
标题翻译：肽和核酸的色谱分离方法，以及新的高亲和力离子交换矩阵
公开(公告)号：US6090288A
公开(公告)日：2000-07-18
申请号：US117678
申请日：1998-12-29
申请人： Rolf Berglund , Jan Bergstrom , Makonnen Belew , Lennart Soderberg
发明人： Rolf Berglund , Jan Bergstrom , Makonnen Belew , Lennart Soderberg
IPC分类号： B01D15/08 , B01D15/36 , B01J41/20 , C07K1/18
CPC分类号： G01N30/482 , B01D15/363 , B01J41/20 , C07K1/18 , B01J2220/54
摘要： Process for separating off a peptide or a nucleic acid by an anion exchanger (I) characterized in that a) the anion exchanger (I) exhibits ligands, which (i) contain a primary, secondary or tertiary amino group and (ii) are covalently bound to an organic polymer (matrix), b) there on a carbon atom at a distance of 2 or 3 atoms away from an amino nitrogen in the ligands is a hydroxyl group or a primary, secondary or tertiary amino group, and c) the maximum elution ionic strength in the pH range 2-14 for at least one of the proteins transferrin, ovalbumin 1, ovalbumin 2, .beta.-lactoglobulin 1 and .beta.-lactoglobulin 2 on the anion exchanger is higher than the elution ionic strength required for a quaternary comparative ion exchanger.
摘要翻译： PCT No.PCT / SE97 / 00237 Sec。 371 1998年12月29日第 102（e）日期1998年12月29日PCT 1997年2月14日提交PCT公布。第WO97 / 29825号公报日期1997年8月21日阴离子交换剂（I）分离肽或核酸的方法，其特征在于a）阴离子交换剂（I）表现出配体，其中（i）含有伯，仲或叔氨基，（ii）与有机聚合物（基体）共价结合，b）在配位体中与氨基氮离开2或3个原子的碳原子处是羟基或伯，仲或叔氨基，和c）阴离子交换剂上至少一种蛋白质转运蛋白，卵白蛋白1，卵白蛋白2，β-乳球蛋白1和β-乳球蛋白2在pH范围2-14中的最大洗脱离子强度高于洗脱离子四级比较离子交换器所需的强度。

3. 发明授权

US5766460A Liquid chromatographic system 失效
标题翻译：液相色谱系统
公开(公告)号：US5766460A
公开(公告)日：1998-06-16
申请号：US779059
申请日：1997-01-06
申请人： Jan Bergstrom , Lennart Soderberg
发明人： Jan Bergstrom , Lennart Soderberg
IPC分类号： B01D15/08 , G01N30/60 , G01N30/88
CPC分类号： B01D15/08 , G01N30/6004 , G01N2030/8881 , G01N30/6034 , G01N30/6047
摘要： A liquid chromatographic system comprises at least two modules, at least one fluid flow line, and at least two connector devices provided along the flow line and respectively connecting the modules to the flow line. One of the two modules comprises a separation module and the other of the two modules comprises an ancillary module having a non-separation function. Each of the two modules includes at least one end connector fit into the respective connector device, and each end connector is adapted to interchangeably fit into either connector device.
摘要翻译：液相色谱系统包括至少两个模块，至少一个流体流动线，以及沿着流动管线设置并分别将模块连接到流动管线的至少两个连接器装置。两个模块之一包括分离模块，并且两个模块中的另一个模块包括具有非分离功能的辅助模块。两个模块中的每一个包括配合到相应连接器装置中的至少一个端部连接器，并且每个端部连接器适于可互换地装配到任一连接器装置中。

4. 发明申请

US20050267295A1 Method for selective removal of a substance from samples containing compounds having nucleic acid structure 审中-公开
标题翻译：从含有具有核酸结构的化合物的样品中选择性去除物质的方法
公开(公告)号：US20050267295A1
公开(公告)日：2005-12-01
申请号：US11076477
申请日：2005-03-09
申请人： Makonnen Belew , Jan Bergstrom , Rolf Berglund , Lennart Soderberg
发明人： Makonnen Belew , Jan Bergstrom , Rolf Berglund , Lennart Soderberg
IPC分类号： C12N15/09 , B01D15/00 , B01D15/08 , B01D15/36 , B01J20/32 , B01J41/20 , C12N15/10 , C07H21/04
CPC分类号： B01J20/3293 , B01D15/363 , B01J20/321 , B01J20/3219 , B01J20/3248 , B01J20/3251 , B01J20/3253 , B01J41/20 , C12N15/1003
摘要： A method for purifying a desired substance by separating from each other a substance (I) from a substance (II), one of which is the desired substance, both of which have affinity for the same ligand structure, and wherein substance (I) is smaller than substance (II). The method comprising the steps of: (i) providing substances I and II in a liquid; (ii) contacting the liquid with an adsorbent which selectively adsorbs substance I; (iii) recovering the desired substance; The adsorbent has (a) an interior part which carries a ligand structure that is capable of binding to substances I and II, and is accessible to substance I, and (b) an outer surface layer that does not adsorb substance II, and is more easily penetrated by substance I than by substance II.
摘要翻译：通过从物质（II）彼此分离出物质（I）的方法，其中一种物质（II）是所需物质，两者对相同的配体结构具有亲和性，并且其中物质（I）为小于物质（II）。该方法包括以下步骤：（i）在液体中提供物质I和II; （ii）使液体与选择性吸附物质I的吸附剂接触; （iii）回收所需物质; 吸附剂具有（a）内部部分，其携带能够结合物质I和II的物质I可接近的配体结构，和（b）不吸附物质II的外表面层，并且更多物质I易于被物质II渗透。

5. 发明申请

US20130302268A1 ACTIVE PRINCIPLE FOR MITIGATING UNDESIRED MEDICAL CONDITIONS 有权
标题翻译：有效的原则，用于减轻不利的医疗条件
公开(公告)号：US20130302268A1
公开(公告)日：2013-11-14
申请号：US13982492
申请日：2012-01-25
申请人： Tim Bowden , Kristoffer Bergman , Thomas Strand , Lennart Soderberg
发明人： Tim Bowden , Kristoffer Bergman , Thomas Strand , Lennart Soderberg
IPC分类号： A61K47/48
CPC分类号： A61K47/58 , A61K9/0014 , A61K31/765 , A61K31/785 , A61K31/787 , A61K47/32 , A61K47/61 , A61L26/00
摘要： A composition for treating or preventing inflammatory-related conditions includes as an active principle a carrier which exhibits a plurality of a scavenger structure capable of mitigating the activity of a mediator of inflammatory-related conditions. The scavenger structure includes a nucleophilic centre complying with the formula X1(—R″—)(—R′)mHnwhere: a) X1 is a single-bonded heteroatom selected amongst N, O and S and exhibits a free electron pair; b) m is 0 or 1 and n is 1 or 2; c) —R″— is a bivalent organic group providing attachment to the carrier via one of its free valences and to X1 at the other free valence; and d) R′— is a monovalent organic group attached to the X1 via its free valence. A method for treating or preventing inflammatory-related conditions in an individual suffering from such conditions includes: providing the composition; and contacting the mediator within or separate from the individual.
摘要翻译：用于治疗或预防炎症相关病症的组合物包括作为活性成分的载体，其显示出能够减轻炎性相关病症介质活性的多种清道夫结构。清除结构包括符合式X1（-R“ - ）（ - R'）mHn的亲核中心，其中：a）X 1是选自N，O和S中的单键合杂原子，并表现出自由电子对; b）m为0或1，n为1或2; c）-R“ - 是通过其自由价之一向载体附着至另一自由价的X1的二价有机基团; 和d）R'是通过其自由价与X1连接的一价有机基团。用于治疗或预防患有这种病症的个体的炎症相关病症的方法包括：提供组合物; 并且在个体内或与个体分开时将介体接触。

6. 发明授权

US5616068A Method and apparatus for grinding peripheral grooves in rolling mill guide rollers 失效
标题翻译：用于研磨轧机导辊的周边槽的方法和装置
公开(公告)号：US5616068A
公开(公告)日：1997-04-01
申请号：US549807
申请日：1995-12-07
申请人： Lennart Soderberg
发明人： Lennart Soderberg
IPC分类号： B24B5/36 , B21B28/02 , B21B39/16 , B24B5/16 , B24B19/06 , B24B1/00
CPC分类号： B24B19/06 , B21B39/165 , B24B5/16 , B21B28/02
摘要： The present invention relates to a method for grinding grooves in the peripheral surface of rollers roller guides for rolling mills. The roller (2) of a roller guide is caused to rotate while retained on its own bearing (8,9,10) as the peripheral groove is ground.The invention also relates to an apparatus for carrying out the method, and to a roller guide structure with which the method can be applied.
摘要翻译： PCT No.PCT / SE94 / 00554 Sec。 371 1995年12月7日第 102（e）日期1995年12月7日PCT Filed 1994年6月8日PCT公布。第WO94 / 29076号公报日期1994年12月22日本发明涉及一种用于研磨辊轧机滚子导轨机周面的槽的方法。滚子导轨的滚轮（2）随着周边凹槽的研磨而保持在自己的轴承（8,9,10）上。本发明还涉及一种用于实施该方法的装置以及可以应用该方法的滚子引导结构。

7. 发明授权

US09302013B2 Active principle for mitigating undesired medical conditions 有权
标题翻译：缓解不良医疗状况的主动原则
公开(公告)号：US09302013B2
公开(公告)日：2016-04-05
申请号：US13982492
申请日：2012-01-25
申请人： Tim Bowden , Kristoffer Bergman , Thomas Engstrand , Lennart Soderberg
发明人： Tim Bowden , Kristoffer Bergman , Thomas Engstrand , Lennart Soderberg
IPC分类号： A61K47/48 , A61K31/765 , A61K31/785
CPC分类号： A61K47/58 , A61K9/0014 , A61K31/765 , A61K31/785 , A61K31/787 , A61K47/32 , A61K47/61 , A61L26/00
摘要： A composition for treating or preventing inflammatory-related conditions includes as an active principle a carrier which exhibits a plurality of a scavenger structure capable of mitigating the activity of a mediator of inflammatory-related conditions. The scavenger structure includes a nucleophilic center complying with the formula X1(—R″—)(—R′)mHn where: a) X1 is a single-bonded heteroatom selected amongst N, O and S and exhibits a free electron pair; b) m is 0 or 1 and n is 1 or 2; c) —R″— is a bivalent organic group providing attachment to the carrier via one of its free valences and to X1 at the other free valence; and d) R′— is a monovalent organic group attached to the X1 via its free valence. A method for treating or preventing inflammatory-related conditions in an individual suffering from such conditions includes: providing the composition; and contacting the mediator within or separate from the individual.
摘要翻译：用于治疗或预防炎症相关病症的组合物包括作为活性成分的载体，其显示出能够减轻炎性相关病症介质活性的多种清道夫结构。清除结构包括符合式X1（-R“ - ）（ - R'）mHn的亲核中心，其中：a）X1是选自N，O和S中的单键合杂原子，并表现出自由电子对; b）m为0或1，n为1或2; c）-R“ - 是一种二价有机基团，其通过其自由价中的一种与另一种游离价的X 1连接至载体; 和d）R'是通过其自由价与X1连接的一价有机基团。用于治疗或预防患有这种病症的个体的炎症相关病症的方法包括：提供组合物; 并且在个体内或与个体分开时将介体接触。

8. 发明授权

US5633921A Providing special services to a caller configured as a virtual called party 失效
标题翻译：为配置为虚拟被叫方的呼叫方提供特殊服务
公开(公告)号：US5633921A
公开(公告)日：1997-05-27
申请号：US615581
申请日：1996-03-12
申请人： Lennart Soderberg
发明人： Lennart Soderberg
IPC分类号： H04M3/00 , H04M3/42 , H04Q3/00 , H04Q3/545 , H04M7/10
CPC分类号： H04M3/4228 , H04Q3/0029 , H04Q3/005 , H04Q2213/13502 , H04Q2213/13513 , H04Q2213/13515 , H04Q2213/13517
摘要： Special subscriber services are implemented by providing operator functionality and service logic within a transit exchange to equip it as a serving node. A subscriber connected to an end office coupled to the transmit exchange invokes the special services functionality by signalling such as by means of a long switch hook flash. Once invoked particular special services may be selected by DTMF or voice prompt signalling.
摘要翻译：通过在运输交换机内提供操作员功能和服务逻辑来将其作为服务节点来实现特殊订户服务。连接到耦合到发送交换机的终端局的用户通过诸如通过长开关钩子闪存的信令来调用特殊服务功能。一旦被调用，可以通过DTMF或语音提示信号来选择特定的特殊服务。

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