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1. 发明授权

US07680240B2 Iterative reconstruction of tomographic image data method and system 有权
标题翻译：断层图像数据方法和系统的迭代重建
公开(公告)号：US07680240B2
公开(公告)日：2010-03-16
申请号：US11731612
申请日：2007-03-30
申请人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , James William Hugg , Charles William Stearns
发明人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , James William Hugg , Charles William Stearns
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/469 , G06T11/006 , G06T2211/424 , G06T2211/432
摘要： Methods for performing image reconstruction that include deriving background projection data for an area outside a targeted field of view of a tomographic image, and reconstructing the tomographic image of the targeted field of view, wherein the background projection data is used in the reconstruction. Methods for selecting a reconstruction methodology that include determining a number of pixels in a reconstructed image for a first reconstruction methodology, determining a number of pixels in a reconstructed image for a second reconstruction methodology, comparing the number of pixels for the first reconstruction methodology and the number of pixels for the second reconstruction methodology, and selecting the reconstruction methodology for image reconstruction based on the comparison of the number of pixels. Imaging systems implementing these methods are also provided.
摘要翻译：用于执行图像重建的方法，包括导出用于断层图像的目标视场外的区域的背景投影数据，以及重构所述目标视场的断层图像，其中所述背景投影数据用于所述重建。用于选择重建方法的方法，所述重建方法包括确定用于第一重建方法的重建图像中的像素数量，确定用于第二重建方法的重建图像中的像素数量，将第一重建方法的像素数与用于第二重建方法的像素数量，以及基于像素数目的比较来选择用于图像重建的重建方法。还提供了实现这些方法的成像系统。

2. 发明申请

US20090225934A1 KEYHOLE COMPUTED TOMOGRAPHY 有权
标题翻译：脑房计算机图
公开(公告)号：US20090225934A1
公开(公告)日：2009-09-10
申请号：US12412160
申请日：2009-03-26
申请人： James William Hugg , Ravindra Mohan Manjeshwar
发明人： James William Hugg , Ravindra Mohan Manjeshwar
IPC分类号： H05G1/60 , G06K9/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/469 , A61B6/488 , G06T11/006 , G06T2211/412 , G06T2211/424
摘要： A method of acquiring and reconstructing a computed tomography (CT) image is provided. A first scan of the full field of view (FOV) is acquired. A second scan of a smaller target FOV is then acquired by using a collimator to narrow the X-ray beam width. The CT image is iteratively reconstructed by replacing a key-hole region of the full FOV projection data with the target FOV projection data. An exemplary embodiment comprises imaging a heart (target FOV) within a torso (full FOV) over multiple heart beat cycles. A computer readable medium is further provided, including a program configured to reconstruct a CT image using the key-hole method.
摘要翻译：提供了一种获取和重建计算机断层摄影（CT）图像的方法。获取全视野（FOV）的第一次扫描。然后通过使用准直器来获取较小目标FOV的第二次扫描以使X射线束宽度变窄。通过用目标FOV投影数据替换全FOV投影数据的键孔区域来迭代地重建CT图像。示例性实施例包括在多个心跳周期内在躯干（全FOV）内成像心脏（目标FOV）。还提供了一种计算机可读介质，其包括被配置为使用所述键孔方法重建CT图像的程序。

3. 发明授权

US07920670B2 Keyhole computed tomography 有权
标题翻译：钥匙孔计算机断层扫描
公开(公告)号：US07920670B2
公开(公告)日：2011-04-05
申请号：US12412160
申请日：2009-03-26
申请人： James William Hugg , Ravindra Mohan Manjeshwar
发明人： James William Hugg , Ravindra Mohan Manjeshwar
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/469 , A61B6/488 , G06T11/006 , G06T2211/412 , G06T2211/424
摘要： A method of acquiring and reconstructing a computed tomography (CT) image is provided. A first scan of the full field of view (FOV) is acquired. A second scan of a smaller target FOV is then acquired by using a collimator to narrow the X-ray beam width. The CT image is iteratively reconstructed by replacing a key-hole region of the full FOV projection data with the target FOV projection data. An exemplary embodiment comprises imaging a heart (target FOV) within a torso (full FOV) over multiple heart beat cycles. A computer readable medium is further provided, including a program configured to reconstruct a CT image using the key-hole method.
摘要翻译：提供了一种获取和重建计算机断层摄影（CT）图像的方法。获取全视野（FOV）的第一次扫描。然后通过使用准直器来获取较小目标FOV的第二次扫描以使X射线束宽度变窄。通过用目标FOV投影数据替换全FOV投影数据的键孔区域来迭代地重建CT图像。示例性实施例包括在多个心跳周期内在躯干（全FOV）内成像心脏（目标FOV）。还提供了一种计算机可读介质，其包括被配置为使用所述键孔方法重建CT图像的程序。

4. 发明申请

US20080240335A1 Iterative reconstruction of tomographic image data method and system 有权
标题翻译：断层图像数据方法和系统的迭代重建
公开(公告)号：US20080240335A1
公开(公告)日：2008-10-02
申请号：US11731612
申请日：2007-03-30
申请人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Henkensfeldt Jansen , James William Hugg , Charles William Stearns
发明人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Henkensfeldt Jansen , James William Hugg , Charles William Stearns
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/469 , G06T11/006 , G06T2211/424 , G06T2211/432
摘要： Methods for performing image reconstruction that include deriving background projection data for an area outside a targeted field of view of a tomographic image, and reconstructing the tomographic image of the targeted field of view, wherein the background projection data is used in the reconstruction. Methods for selecting a reconstruction methodology that include determining a number of pixels in a reconstructed image for a first reconstruction methodology, determining a number of pixels in a reconstructed image for a second reconstruction methodology, comparing the number of pixels for the first reconstruction methodology and the number of pixels for the second reconstruction methodology, and selecting the reconstruction methodology for image reconstruction based on the comparison of the number of pixels. Imaging systems implementing these methods are also provided.
摘要翻译：用于执行图像重建的方法，包括导出用于断层图像的目标视场外的区域的背景投影数据，以及重构所述目标视场的断层图像，其中所述背景投影数据用于所述重建。用于选择重建方法的方法，所述重建方法包括确定用于第一重建方法的重建图像中的像素数量，确定用于第二重建方法的重建图像中的像素数量，将第一重建方法的像素数与用于第二重建方法的像素数量，以及基于像素数目的比较来选择用于图像重建的重建方法。还提供了实现这些方法的成像系统。

5. 发明申请

US20140064446A1 X-RAY ABSORPTIOMETRY USING SOLID-STATE PHOTOMULTIPLIERS 审中-公开
标题翻译：使用固态光催化剂的X射线吸收
公开(公告)号：US20140064446A1
公开(公告)日：2014-03-06
申请号：US13605493
申请日：2012-09-06
申请人： James A. Wear , Sergei Dolinsky , Randall Payne , Ravindra Mohan Manjeshwar
发明人： James A. Wear , Sergei Dolinsky , Randall Payne , Ravindra Mohan Manjeshwar
IPC分类号： G01T1/20 , G01N23/04
CPC分类号： G01N23/04 , G01T1/2018 , G01T1/208
摘要： An x-ray absorptiometry apparatus and method utilize a radiation source having a beam opening angle of less than or equal to 30 milliradians in at least one dimension, an array of scintillator units to receive radiation from the radiation source with the beam angle after the radiation has passed through a body being imaged and at least one solid-state photomultiplier to receive photons from the array of scintillator units and to produce electrical signal based on the photons. In one implementation, an optical area transmission passage modifier is employed in a dual energy x-ray absorptiometry system. In one implementation, the array of scintillator units are arranged in staggered rows. In yet another implementation, the solid-state photomultiplier includes a plurality of solid-state photomultipliers arranged in rows. In one implementation, a single solid-state photomultiplier receive photons from a plurality of scintillators of the array.
摘要翻译： X射线吸收测定装置和方法利用在至少一个维度上具有小于或等于30毫弧度的光束开启角的辐射源，用于接收来自辐射源的辐射的闪烁体单元阵列，其具有在辐射之后的束角度已经通过被成像的身体和至少一个固态光电倍增管，以从闪烁体单元阵列接收光子并产生基于光子的电信号。在一个实施方案中，在双能X射线吸收测定系统中采用光学区域传输通道改进剂。在一个实现中，闪烁体单元阵列以交错排布置。在又一实施方式中，固态光电倍增管包括排成行的多个固态光电倍增管。在一个实施方案中，单个固态光电倍增管从阵列的多个闪烁体接收光子。

6. 发明申请

US20130026370A1 METHODS AND SYSTEMS FOR SCATTER ESTIMATION IN POSITRON EMISSION TOMOGRAPHY 有权
标题翻译：方法和系统在排气排放测量中的散射估计
公开(公告)号：US20130026370A1
公开(公告)日：2013-01-31
申请号：US13191205
申请日：2011-07-26
申请人： Hua Qian , Ravindra Mohan Manjeshwar , Kris Filip Johan Jules Thielemans
发明人： Hua Qian , Ravindra Mohan Manjeshwar , Kris Filip Johan Jules Thielemans
IPC分类号： G01T1/164
CPC分类号： G01T1/1615 , A61B6/037 , G06T11/005
摘要： Methods and systems for multiple scatter estimation in Positron Emission Tomography (PET) are provided. One method includes determining attenuation sinograms and determining a varying convolution kernel as a function of the attenuation sinograms, wherein the kernel varies in amplitude and width over a radial length of a PET imaging system. The method also includes using the varying convolution kernel to estimate multiple PET scatter.
摘要翻译：提供了正电子发射断层扫描（PET）中多重散射估计的方法和系统。一种方法包括确定衰减正弦图并确定作为衰减正弦图的函数的变化的卷积核，其中所述核在PET成像系统的径向长度上的幅度和宽度上变化。该方法还包括使用变化的卷积核估计多个PET散射。

7. 发明申请

US20110158494A1 SYSTEMS AND METHODS FOR IDENTIFYING BONE MARROW IN MEDICAL IMAGES 有权
标题翻译：用于识别医学图像中骨骼大小的系统和方法
公开(公告)号：US20110158494A1
公开(公告)日：2011-06-30
申请号：US12650036
申请日：2009-12-30
申请人： Avi Bar-Shalev , Ravindra Mohan Manjeshwar
发明人： Avi Bar-Shalev , Ravindra Mohan Manjeshwar
IPC分类号： G06K9/00 , G06T17/00
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/505 , A61B6/508 , A61B6/5241 , G06K9/00 , G06T7/11 , G06T7/13 , G06T7/187 , G06T2207/10081 , G06T2207/20164 , G06T2207/30008
摘要： Systems and method for identifying bone marrow in medical images are provided. A method includes obtaining a three-dimensional (3D) computed tomography (CT) volume data set corresponding to an imaged volume and identifying voxels in the 3D CT volume data set having a Hounsfield Unit (HU) value below a bone threshold. The voxels are identified without using image continuity. The method further includes marking the identified voxels as non-bone voxels, determining definite tissue voxels based on the identified non-bone voxels and expanding a region defined by the definite tissue voxels. The method also includes segmenting the expanded region to identify bone voxels and bone marrow voxels and identifying bone marrow as voxels that are not the bone voxels.
摘要翻译：提供了用于鉴定医学图像中骨髓的系统和方法。一种方法包括获得对应于成像体积的三维（3D）计算机断层摄影（CT）体数据集，并且在具有低于骨阈值的Hounsfield单位（HU）值的3D CT体积数据集中识别体素。识别体素而不使用图像连续性。该方法还包括将所识别的体素标记为非骨体素，基于所识别的非骨体素来确定确定的组织体素并且扩展由所述确定的组织体素定义的区域。该方法还包括分割扩大区域以鉴定骨骼体素和骨髓体素，并将骨髓识别为不是骨骼体素的体素。

8. 发明申请

US20100193697A1 APPARATUS AND METHODS FOR EVALUATING OPERATION OF PIXELATED DETECTORS 有权
标题翻译：用于评估像素检测器操作的装置和方法
公开(公告)号：US20100193697A1
公开(公告)日：2010-08-05
申请号：US12365100
申请日：2009-02-03
申请人： Girish Bal , Floribertus Heukensfeldt Jansen , Osnat Zak , Gideon Berlad , Yaron Hefetz , Sergei Dolinsky , Brian D. Yanoff , John Eric Tkaczyk , Yanfeng Du , Ravindra Mohan Manjeshwar , Evren Asma , Qian Hua
发明人： Girish Bal , Floribertus Heukensfeldt Jansen , Osnat Zak , Gideon Berlad , Yaron Hefetz , Sergei Dolinsky , Brian D. Yanoff , John Eric Tkaczyk , Yanfeng Du , Ravindra Mohan Manjeshwar , Evren Asma , Qian Hua
IPC分类号： G01T1/00 , G01T1/172
CPC分类号： G01T1/249 , G01T1/247
摘要： An apparatus and methods for evaluating the operation of pixelated detectors are provided. The method includes obtaining data values for each of a plurality of pixels of a pixelated detector and determining a data consistency metric for each of the plurality of detector pixels. The method further includes identifying, using the determined data consistency metric, any detector pixels that exceed an acceptance criterion as noisy pixels.
摘要翻译：提供了一种用于评估像素化检测器的操作的装置和方法。该方法包括获得像素化检测器的多个像素中的每一个的数据值，并确定多个检测器像素中的每一个的数据一致性度量。该方法还包括使用所确定的数据一致性度量来识别超过接受标准的任何检测器像素作为噪声像素。

9. 发明授权

US07518114B2 Method and system for imaging a patient 有权
标题翻译：用于对患者进行成像的方法和系统
公开(公告)号：US07518114B2
公开(公告)日：2009-04-14
申请号：US10985752
申请日：2004-11-10
申请人： Alexander Ganin , Floribertus Philippus Martinus Heukensfeldt Jansen , Ricardo Scott Avila , Dinko Eduardo Gonzalez Trotter , Ravindra Mohan Manjeshwar , James Vradenburg Miller , Thomas Baby Sebastian
发明人： Alexander Ganin , Floribertus Philippus Martinus Heukensfeldt Jansen , Ricardo Scott Avila , Dinko Eduardo Gonzalez Trotter , Ravindra Mohan Manjeshwar , James Vradenburg Miller , Thomas Baby Sebastian
IPC分类号： G01T1/164 , G01T1/166
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1611 , G01T1/1615
摘要： Methods and systems for imaging a patient are provided. The method includes determining a location of a volume of interest within the patient and acquiring a plurality of frames of emission data, at least one frame including the volume of interest. The method further includes determining a time-of-flight (TOF) information of at least a portion of the annihilations detected along a line of response between corresponding coincidence detectors and generating an image of the patient from the emission data using the determined TOF information.
摘要翻译：提供了用于成像患者的方法和系统。该方法包括确定患者体内感兴趣体积的位置并获取多个发射数据帧，至少一帧包括感兴趣的体积。该方法还包括确定在相应的重合检测器之间沿着响应线检测到的湮灭的至少一部分的飞行时间（TOF）信息，并使用确定的TOF信息从发射数据生成患者的图像。

10. 发明授权

US07211799B2 Method and system for calibrating a time of flight positron emission tomography system 有权
标题翻译：校准飞行时间正电子发射断层扫描系统的方法和系统
公开(公告)号：US07211799B2
公开(公告)日：2007-05-01
申请号：US11226171
申请日：2005-09-14
申请人： Floribertus P. M. Heukensfeldt Jansen , Ravindra Mohan Manjeshwar
发明人： Floribertus P. M. Heukensfeldt Jansen , Ravindra Mohan Manjeshwar
IPC分类号： G01T1/161
CPC分类号： G01T1/2985
摘要： A method and system for calibrating a Time of Flight Positron Emission Tomography (TOF PET) system are provided. The method includes storing acquired scan data from detector pairs. The acquired scan data includes image data and timing information. The method further includes reconstructing images using scan data. The method also includes determining a timing correction for each detector based on intensity distribution histograms of emission sources. The system includes a controller, which is configured to perform the above-mentioned method steps.
摘要翻译：提供了一种用于校准飞行时间正电子发射断层扫描（TOF PET）系统的方法和系统。该方法包括从检测器对存储获取的扫描数据。获取的扫描数据包括图像数据和定时信息。该方法还包括使用扫描数据重建图像。该方法还包括基于发射源的强度分布直方图确定每个检测器的定时校正。该系统包括控制器，其被配置为执行上述方法步骤。

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