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1. 发明授权

US07736382B2 Apparatus for optical stimulation of nerves and other animal tissue 有权
标题翻译：用于光学刺激神经和其他动物组织的装置
公开(公告)号：US07736382B2
公开(公告)日：2010-06-15
申请号：US11257793
申请日：2005-10-24
申请人： James S. Webb , Charles E. Hamilton , Heather A. Ralph , Mark P. Bendett , Charles A. Lemaire
发明人： James S. Webb , Charles E. Hamilton , Heather A. Ralph , Mark P. Bendett , Charles A. Lemaire
IPC分类号： A61N5/067
CPC分类号： A61N5/0601 , A61B18/20 , A61B90/37 , A61B2017/00115 , A61B2017/00384 , A61B2017/00973 , A61B2018/00922 , A61B2018/00958 , A61B2018/2065 , A61B2018/207 , A61B2018/2075 , A61N5/0622 , A61N2005/0629 , A61N2005/063 , A61N2005/0644 , A61N2005/0651 , A61N2005/0659 , A61N2005/067
摘要： A nerve-stimulation device and method using light to provide a source of precise stimulation on one or more nerve fibers. In some embodiments, this simulation is provided through a device and method wherein a laser- or LED-light-generating source is operatively coupled to an optical fiber, which in turn is coupled to a plug in the end of a holder in a sheath. Light is then passed from the light source through the optical fiber to the holder and out a selected optical tip on the sheath to provide an efficacious amount of light to simulate nerves. In some embodiments, the device is constructed from non-magnetic material such as glass, plastic or ceramics. In some embodiments, the light emanating from the optical tip can be controlled manually or automatically. Some embodiments omit the fiber and use light directly from the laser diode.
摘要翻译：一种神经刺激装置和方法，使用光提供一个或多个神经纤维上的精确刺激源。在一些实施例中，通过设备和方法来提供该模拟，其中激光或LED发光源可操作地耦合到光纤，光纤又连接到护套中的保持器的端部中的插头。然后，光从光源通过光纤传送到保持器，并从外壳上选出一个选定的光学尖端，以提供有效量的光来模拟神经。在一些实施例中，该装置由诸如玻璃，塑料或陶瓷的非磁性材料构成。在一些实施例中，可以手动或自动地控制从光学尖端发出的光。一些实施例省略光纤并直接从激光二极管使用光。

2. 发明授权

US08985119B1 Method and apparatus for optical stimulation of nerves and other animal tissue 有权
标题翻译：用于光学刺激神经和其他动物组织的方法和装置
公开(公告)号：US08985119B1
公开(公告)日：2015-03-24
申请号：US12797544
申请日：2010-06-09
申请人： James S. Webb , Charles E. Hamilton , Heather A. Ralph , Mark P. Bendett , Charles A. Lemaire
发明人： James S. Webb , Charles E. Hamilton , Heather A. Ralph , Mark P. Bendett , Charles A. Lemaire
IPC分类号： A61B19/00 , A61N5/06
CPC分类号： A61N5/0601 , A61B18/20 , A61B90/37 , A61B2017/00115 , A61B2017/00384 , A61B2017/00973 , A61B2018/00922 , A61B2018/00958 , A61B2018/2065 , A61B2018/207 , A61B2018/2075 , A61N5/0622 , A61N2005/0629 , A61N2005/063 , A61N2005/0644 , A61N2005/0651 , A61N2005/0659 , A61N2005/067
摘要： A nerve-stimulation device and method using light to provide a source of precise stimulation on one or more nerve fibers. In some embodiments, this simulation is provided through a device and method wherein a laser- or LED-light-generating source is operatively coupled to an optical fiber, which in turn is coupled to a plug in the end of a holder in a sheath. Light is then passed from the light source through the optical fiber to the holder and out a selected optical tip on the sheath to provide an efficacious amount of light to simulate nerves. In some embodiments, the device is constructed from non-magnetic material such as glass, plastic or ceramics. In some embodiments, the light emanating from the optical tip can be controlled manually or automatically. Some embodiments omit the fiber and use light directly from the laser diode.
摘要翻译：一种神经刺激装置和方法，使用光提供一个或多个神经纤维上的精确刺激源。在一些实施例中，通过设备和方法来提供该模拟，其中激光或LED发光源可操作地耦合到光纤，光纤又连接到护套中的保持器的端部中的插头。然后，光从光源通过光纤传送到保持器，并从外壳上选出一个选定的光学尖端，以提供有效量的光来模拟神经。在一些实施例中，该装置由诸如玻璃，塑料或陶瓷的非磁性材料构成。在一些实施例中，可以手动或自动地控制从光学尖端发出的光。一些实施例省略光纤并直接从激光二极管使用光。

3. 发明授权

US07535631B2 Method and apparatus for spectral-beam combining of fiber-amplified laser beams using high-efficiency dielectric diffractive gratings 有权
$Method and apparatus for spectral-beam combining of fiber-amplified laser beams using high-efficiency dielectric diffractive gratings$
标题翻译：使用高效介质衍射光栅的光纤放大激光束的光束组合的方法和装置
公开(公告)号：US07535631B2
公开(公告)日：2009-05-19
申请号：US11751637
申请日：2007-05-22
申请人： Andrew J. W. Brown , Eric C. Honea , Thomas H. Loftus , Roy D. Mead , Charles E. Hamilton , Anping Liu , Charles A. Lemaire
发明人： Andrew J. W. Brown , Eric C. Honea , Thomas H. Loftus , Roy D. Mead , Charles E. Hamilton , Anping Liu , Charles A. Lemaire
IPC分类号： H04B10/17 , H01S3/00
CPC分类号： G02B27/1086 , G02B27/1006 , G02B27/108 , G02B27/123 , G02B27/144 , G02B27/145
摘要： Apparatus and method for spectral-beam combining light from a plurality of high-power fiber lasers that, in some embodiments, use two substantially identical diffraction gratings in a parallel, mutually compensating configuration to combine a plurality of separate parallel input beams each having a slightly different successively higher wavelength into a single output beam of high quality. In other embodiments, a single diffraction grating is used to combine a plurality of different wavelengths, wherein the input laser beams are obtained from very narrow linewidth sources to reduce chromatic dispersion. In some embodiments, diagnostics and adjustments of wavelengths and/or positions and angles are made dynamically in real time to maintain the combination of the plurality input beams into a single high-quality output beam.
摘要翻译：在多个高功率光纤激光器中对光束进行光束组合的装置和方法，其在一些实施例中使用两个基本相同的衍射光栅，并联的相互补偿的结构，以组合多个独立的并行输入光束，不同的连续更高的波长成为高质量的单个输出光束。在其他实施例中，使用单个衍射光栅来组合多个不同的波长，其中输入激光束从非常窄的线宽源获得以减少色散。在一些实施例中，实时动态地进行波长和/或位置和角度的诊断和调整，以将多个输入光束的组合保持为单个高质量输出光束。

4. 发明授权

US08472763B1 Spectral beam combination of laser beams 有权
标题翻译：激光束的光束组合
公开(公告)号：US08472763B1
公开(公告)日：2013-06-25
申请号：US13043342
申请日：2011-03-08
申请人： Anping Liu , Eric C. Honea , Charles A. Lemaire , Roy D. Mead , Christopher D. Brooks , Andrew J. W. Brown , Charles E. Hamilton , Thomas H. Loftus , Fabio Di Teodoro
发明人： Anping Liu , Eric C. Honea , Charles A. Lemaire , Roy D. Mead , Christopher D. Brooks , Andrew J. W. Brown , Charles E. Hamilton , Thomas H. Loftus , Fabio Di Teodoro
IPC分类号： G02B6/34 , G02B6/26 , G02B4/42
CPC分类号： G02B6/3853 , C03B37/10 , G02B6/02328 , G02B6/02347 , G02B6/02376 , G02B6/02385 , G02B6/3826 , H01S3/005 , H01S3/0064 , H01S3/0078 , H01S3/06704 , H01S3/06708 , H01S3/06729 , H01S3/06741 , H01S3/06745 , H01S3/06754 , H01S3/06758 , H01S3/094007
摘要： A method and apparatus use a photonic-crystal fiber having a very large core while maintaining a single transverse mode. In some fiber lasers and amplifiers having large cores problems exist related to energy being generated at multiple-modes (i.e., polygamy), and of mode hopping (i.e., promiscuity) due to limited control of energy levels and fluctuations. The problems of multiple-modes and mode hopping result from the use of large-diameter waveguides, and are addressed by the invention. This is especially true in lasers using large amounts of energy (i.e., lasers in the one-megawatt or more range). By using multiple small waveguides in parallel, large amounts of energy can be passed through a laser, but with better control such that the aforementioned problems can be reduced. An additional advantage is that the polarization of the light can be maintained better than by using a single fiber core.
摘要翻译：一种方法和装置使用具有非常大核心的光子晶体光纤，同时保持单个横向模式。在一些光纤激光器和具有大的核心问题的放大器存在与在多模式（即一夫多妻制）下产生的能量以及由于能量水平和波动的有限控制而导致的模式跳变（即，混乱）有关的问题。使用大直径波导导致多模和跳频的问题，并由本发明解决。在使用大量能量的激光器（即，1兆瓦或更大范围的激光器）中尤其如此。通过平行地使用多个小波导，可以将大量能量通过激光器，但是具有更好的控制，从而可以减少上述问题。另外的优点是可以比通过使用单个纤芯更好地保持光的偏振。

5. 发明授权

US07233442B1 Method and apparatus for spectral-beam combining of high-power fiber lasers 有权
标题翻译：高功率光纤激光器的光束组合方法和装置
公开(公告)号：US07233442B1
公开(公告)日：2007-06-19
申请号：US11342337
申请日：2006-01-26
申请人： Andrew J. W. Brown , Eric C. Honea , Thomas H. Loftus , Roy D. Mead , Charles E. Hamilton , Anping Liu , Charles A. Lemaire
发明人： Andrew J. W. Brown , Eric C. Honea , Thomas H. Loftus , Roy D. Mead , Charles E. Hamilton , Anping Liu , Charles A. Lemaire
IPC分类号： G02B27/64
CPC分类号： G02B27/1086 , G02B27/1006 , G02B27/108 , G02B27/123 , G02B27/144 , G02B27/145
摘要： Apparatus and method for spectral-beam combining light from a plurality of high-power fiber lasers that, in some embodiments, use two substantially identical diffraction gratings in a parallel, mutually compensating configuration to combine a plurality of separate parallel input beams each having a slightly different successively higher wavelength into a single output beam of high quality. In other embodiments, a single diffraction grating is used to combine a plurality of different wavelengths, wherein the input laser beams are obtained from very narrow linewidth sources to reduce chromatic dispersion. In some embodiments, diagnostics and adjustments of wavelengths and/or positions and angles are made dynamically in real time to maintain the combination of the plurality input beams into a single high-quality output beam.
摘要翻译：在多个高功率光纤激光器中对光束进行光束组合的装置和方法，其在一些实施例中使用两个基本相同的衍射光栅，并联的相互补偿的结构，以组合多个独立的并行输入光束，不同的连续更高的波长成为高质量的单个输出光束。在其他实施例中，使用单个衍射光栅来组合多个不同的波长，其中输入激光束从非常窄的线宽源获得以减少色散。在一些实施例中，实时动态地进行波长和/或位置和角度的诊断和调整，以将多个输入光束的组合保持为单个高质量输出光束。

6. 发明授权

US07199924B1 Apparatus and method for spectral-beam combining of high-power fiber lasers 有权
标题翻译：大功率光纤激光器的光束组合装置及方法
公开(公告)号：US07199924B1
公开(公告)日：2007-04-03
申请号：US11342336
申请日：2006-01-26
申请人： Andrew J. W. Brown , Eric C. Honea , Thomas H. Loftus , Roy D. Mead , Charles E. Hamilton , Anping Liu , Charles A. Lemaire
发明人： Andrew J. W. Brown , Eric C. Honea , Thomas H. Loftus , Roy D. Mead , Charles E. Hamilton , Anping Liu , Charles A. Lemaire
IPC分类号： H04J14/02 , G02B27/64
CPC分类号： H01S3/2383 , G02B6/2931 , G02B27/1006 , G02B27/108 , G02B27/1086 , G02B27/123 , G02B27/144 , G02B27/145 , H01S3/005 , H01S3/0675 , H01S3/08009 , H01S3/2308 , H01S3/2391
摘要： Apparatus and method for spectral-beam combining light from a plurality of high-power fiber lasers that, in some embodiments, use two substantially identical diffraction gratings in a parallel, mutually compensating configuration to combine a plurality of separate parallel input beams each having a slightly different successively higher wavelength into a single output beam of high quality. In other embodiments, a single diffraction grating is used to combine a plurality of different wavelengths, wherein the input laser beams are obtained from very narrow linewidth sources to reduce chromatic dispersion. In some embodiments, diagnostics and adjustments of wavelengths and/or positions and angles are made dynamically in real time to maintain the combination of the plurality input beams into a single high-quality output beam.
摘要翻译：在多个高功率光纤激光器中对光束进行光束组合的装置和方法，其在一些实施例中使用两个基本相同的衍射光栅，并联的相互补偿的结构，以组合多个独立的并行输入光束，不同的连续更高的波长成为高质量的单个输出光束。在其他实施例中，使用单个衍射光栅来组合多个不同的波长，其中输入激光束从非常窄的线宽源获得以减少色散。在一些实施例中，实时动态地进行波长和/或位置和角度的诊断和调整，以将多个输入光束的组合保持为单个高质量输出光束。

7. 发明授权

US07065107B2 Spectral beam combination of broad-stripe laser diodes 有权
标题翻译：宽带激光二极管的光束组合
公开(公告)号：US07065107B2
公开(公告)日：2006-06-20
申请号：US10687495
申请日：2003-10-16
申请人： Charles E. Hamilton , Dennis D Lowenthal , Roy D. Mead
发明人： Charles E. Hamilton , Dennis D Lowenthal , Roy D. Mead
IPC分类号： H01S3/098 , H01S3/08
CPC分类号： H01S5/141 , H01S3/0805 , H01S5/4062
摘要： A method and apparatus for improving the beam quality of the emissions from a multimode gain medium such as a broad-stripe laser through the use of SBC techniques is provided. In order to achieve the desired beam quality without a significant reduction in output power, discrete lasing regions are formed across the gain medium using an etalon or similar device located within the SBC cavity.
摘要翻译：提供了一种用于通过使用SBC技术来改善诸如宽条激光器的多模增益介质的发射的光束质量的方法和装置。为了实现期望的光束质量而没有输出功率的显着降低，使用位于SBC腔内的标准具或类似装置在增益介质之间形成分立的激光区域。

8. 发明授权

US5623510A Tunable, diode side-pumped Er: YAG laser 失效
标题翻译：可调谐二极管侧泵浦Er：YAG激光器
公开(公告)号：US5623510A
公开(公告)日：1997-04-22
申请号：US436690
申请日：1995-05-08
申请人： Charles E. Hamilton , Laurence H. Furu
发明人： Charles E. Hamilton , Laurence H. Furu
IPC分类号： H01S3/081 , H01S3/0941 , H01S3/106 , H01S3/16 , H01S3/091 , H01S3/094
CPC分类号： H01S3/0941 , H01S3/081 , H01S3/1062 , H01S3/1608 , H01S3/1643
摘要： A discrete-element Er:YAG laser, side pumped by a 220 Watt peak-power InGaAs diode array, generates >500 mWatts at 2.94 .mu.m, and is tunable over a 6 nm range near about 2.936 .mu.m. The oscillator is a plano-concave resonator consisting of a concave high reflector, a flat output coupler, a Er:YAG crystal and a YAG intracavity etalon, which serves as the tuning element. The cavity length is variable from 3 cm to 4 cm. The oscillator uses total internal reflection in the Er:YAG crystal to allow efficient coupling of the diode emission into the resonating modes of the oscillator. With the tuning element removed, the oscillator produces up to 1.3 Watts of average power at 2.94 .mu.m. The duty factor of the laser is 6.5% and the repetition rate is variable up to 1 kHz. This laser is useful for tuning to an atmospheric transmission window at 2.935 .mu.m (air wavelength). The laser is also useful as a spectroscopic tool because it can access several infrared water vapor transitions, as well as transitions in organic compounds. Other uses include medical applications (e.g., for tissue ablation and uses with fiber optic laser scalpels) and as part of industrial effluent monitoring systems.
摘要翻译：由220瓦峰值功率InGaAs二极管阵列泵浦的离散元件Er：YAG激光器，在2.94微米处产生> 500mWat，并且在约2.936μm附近可调谐超过6nm。该振荡器是由凹高反射器，扁平输出耦合器，Er：YAG晶体和YAG腔内标准具组成的平凹谐振器，用作调谐元件。腔长度从3厘米到4厘米不等。振荡器在Er：YAG晶体中使用全内反射，以使二极管发射有效耦合到振荡器的谐振模式。调谐元件去除后，振荡器产生高达1.3瓦的平均功率为2.94微米。激光器的占空比为6.5％，重复率可变为1 kHz。该激光器可用于调谐到2.935微米（空气波长）的大气透射窗口。激光也可用作光谱工具，因为它可以访问几个红外水蒸气跃迁以及有机化合物的转变。其他用途包括医疗应用（例如用于组织消融和使用光纤激光解剖刀），并且作为工业污水监测系统的一部分。

9. 发明授权

US5081630A Tunable pulsed titanium:sapphire laser and conditions for its operation 失效
标题翻译：可调脉冲钛：蓝宝石激光器及其操作条件
公开(公告)号：US5081630A
公开(公告)日：1992-01-14
申请号：US414886
申请日：1989-09-29
申请人： Dennis D. Lowenthal , Clifford H. Muller , Charles E. Hamilton , Dean R. Guyer , Kenneth W. Kangas
发明人： Dennis D. Lowenthal , Clifford H. Muller , Charles E. Hamilton , Dean R. Guyer , Kenneth W. Kangas
IPC分类号： H01S3/08 , H01S3/1055
CPC分类号： H01S3/1055 , H01S3/08036
摘要： A laser system for producing pulsed, longitudinal mode optical energy over a widely tunable range of wavelengths. The system includes an optical cavity and a solid-state gain medium. The optical cavity comprises first, second, and third optical element means. The first optical element means reflects energy received along a first reflective optical axis and directs the energy toward the second optical element means, which diffracts the optical energy into at least two orders of interference. The energy diffracted according to a first order of interference is reflected back toward the second optical element means by a third optical element means, thereby creating a resonant optical cavity. Another portion of the optical energy diffracted by the second optical element means is produced as an output beam. The solid-state gain medium is located on the optical axis between the first and second optical element means and receives pump energy from a plurality of pump beams that are within two degrees of being colinear with the first reflective optical axis. The solid-state gain medium converts the pump beam energy to optical energy having a desired wavelength with a very high efficiency, without required pump beam energy densities above a predetermined level. The laser system is tunable by moving the third optical element means with respect to the second optical element means, thereby causing optical energy at a tunable wavelength to resonate within the optical cavity.
摘要翻译：一种用于在广泛可调波长范围内产生脉冲，纵向模式光能的激光系统。该系统包括光腔和固态增益介质。光腔包括第一，第二和第三光学元件装置。第一光学元件意味着反射沿着第一反射光轴接收的能量并且将能量引导到第二光学元件装置，其将光能衍射为至少两个干涉级。根据第一干涉级衍射的能量通过第三光学元件装置反射回第二光学元件装置，由此产生共振光学腔。产生由第二光学元件装置衍射的光能的另一部分作为输出光束。固态增益介质位于第一和第二光学元件装置之间的光轴上，并且从与第一反射光轴共线的两个角度内的多个泵浦光束接收泵浦能量。固态增益介质以非常高的效率将泵浦能量转换成具有期望波长的光能，而不需要高于预定水平的泵浦光束能量密度。激光系统可通过相对于第二光学元件装置移动第三光学元件装置来调节，从而使可调波长的光能在光学腔内谐振。

10. 发明授权

US4805343A Osmotic fiber systems 失效
标题翻译：渗透纤维系统
公开(公告)号：US4805343A
公开(公告)日：1989-02-21
申请号：US920440
申请日：1986-10-20
申请人： James A. Patterson , Robert M. Piecuch , Charles E. Hamilton
发明人： James A. Patterson , Robert M. Piecuch , Charles E. Hamilton
IPC分类号： A01G27/04 , B01D63/02 , B01D67/00 , B01D69/08 , A01G27/00
CPC分类号： B01D67/0086 , A01G27/04 , B01D63/02 , B01D67/0088 , B01D69/08 , B01D2313/23
摘要： A hollow fiber formed of hydrophilic material and having permeable walls is treated to enhance the permeability. Reactions used to treat the fiber have a gas inside and gas outside, a gas inside and liquid outside, a liquid inside and gas outside, and a liquid inside and a liquid outside. The treatments generally involve the plasticizing of the fiber material while having the inside of the fiber at a higher pressure than the outside. These treatments produce a structural change in the fiber from a flexible tube having strong walls to expanded, rigid and somewhat fragile walls. Where more than a short length of the treated fiber is to be used, an open mesh cage is used to confine the fiber to a desired volume during treatment and to protect it subsequently. A technique for joining flexible tubing to the treated fiber is presented. The treated fiber may be used in apparatus and methods involving osmosis and reverse osmosis. Novel plant irrigation methods and apparatus are disclosed, and structures for changing the solvent quanties of solutes and measuring the osmotic pressures of solutions are also presented.
摘要翻译：处理由亲水材料形成且具有可渗透壁的中空纤维以增强渗透性。用于处理纤维的反应具有内部气体和外部气体，内部气体和液体外部，内部液体和气体外部，以及液体内部和液体外部。处理通常涉及纤维材料的增塑，同时纤维内部的压力高于外部。这些处理从具有强壁的柔性管到膨胀的，刚性的和稍微脆弱的壁产生纤维中的结构变化。在使用多于短长度的经处理的纤维的情况下，使用开式网状笼来在处理期间将纤维限制在所需体积并随后进行保护。提出了将柔性管连接到经处理的纤维的技术。经处理的纤维可用于涉及渗透和反渗透的设备和方法中。还提出了新型植物灌溉方法和装置，并提出了改变溶质溶剂量和测定溶液渗透压的结构。

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