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1. 发明授权

US5368017A Apparatus for ventilating and aspirating 失效
标题翻译：用于通风和吸气的装置
公开(公告)号：US5368017A
公开(公告)日：1994-11-29
申请号：US848030
申请日：1992-03-09
申请人： James L. Sorenson , Valdon G. Reynolds , Stephen C. Mackert , Joseph H. Jeffs , David W. Kaufman
发明人： James L. Sorenson , Valdon G. Reynolds , Stephen C. Mackert , Joseph H. Jeffs , David W. Kaufman
IPC分类号： A61M1/00 , A61M16/04 , A61M25/01 , A61M16/00
CPC分类号： A61M16/0463 , A61M1/0047 , A61M2205/32 , A61M25/0111 , Y10S128/912
摘要： A ventilating and aspirating apparatus for delivering respiratory gases to the trachea and the congested lungs and breathing passageways of a patient includes a flexible catheter tube extendable into and withdrawable from the patient's trachea. The catheter is housed within a pliable sheath extending from a manifold that is attachable to an endotracheal tube. The sheath has a slit defined by backing members formed along elongate opposed edges. A releasable, air tight "ziplock" seal is effected at the slit by a bead on one backing member and a groove to sealingly receive the bead on the other backing member. A "ziplock" actuator is structured as a slider member which travels along the bead and groove, and includes converging ends to hold the bead in the groove and a conduit member extending centrally through the slider member to interconnect an end of the catheter tube inside the sheath through a vacuum valve carried by the slider member outside the sheath to a vacuum source. The vacuum valve is operable by the same hand of a user that may be used to move the slider member.
摘要翻译：用于将呼吸气体输送到气管和拥堵的肺部以及患者的呼吸通道的通气和抽吸装置包括可延伸到患者气管中并可从患者气管中取出的柔性导管。导管容纳在从可附接到气管插管的歧管延伸的柔韧护套内。鞘具有由沿着细长的相对边缘形成的背衬构件限定的狭缝。通过一个背衬构件上的凸缘和凹槽来在狭缝处实现可释放的气密“拉锁”密封，以密封地容纳另一个背衬构件上的凸珠。 “拉锁”致动器被构造为沿着胎圈和沟槽行进的滑动构件，并且包括会聚端部以将胎圈保持在槽中;以及导管构件，其中心地延伸穿过滑动构件，以将导管管的端部护套通过真空阀将滑动件承载在护套外面到真空源。真空阀可通过可用于移动滑动构件的使用者的手来操作。

2. 发明授权

US5181916A Surgical probe and smoke eliminator 失效
标题翻译：外科手术和烟熏消除器
公开(公告)号：US5181916A
公开(公告)日：1993-01-26
申请号：US693229
申请日：1991-04-26
申请人： Valdon G. Reynolds , James L. Sorenson , Gordon S. Reynolds
发明人： Valdon G. Reynolds , James L. Sorenson , Gordon S. Reynolds
IPC分类号： A61B18/20 , A61B18/00 , A61M1/00
CPC分类号： A61M1/008 , A61B2218/008 , Y10S604/902
摘要： The invention comprises a handpiece for use in a surgical procedure which involves directing a surgical agent to a target area of a person's body which procedure produces an unwanted smoke plume. The handpiece includes both a probe for directing a surgical agent, such as a CO.sub.2 laser beam, and a smoke eliminator for removing with suction the smoke created by the surgical procedure. The probe has no functional components for creating the laser beam, and is thus economical enough to be disposable after one use. The smoke eliminator includes a nozzle and/or an offset suction port so configured as to create a votrex flow in the smoke in the target area upstream in the fluid flow pathway of smoke through the hand piece from the distal tip of the hand piece.
摘要翻译：本发明包括用于外科手术的手持件，其涉及将手术器官引导到人体的目标区域，该程序产生不想要的烟羽。手持件包括用于引导诸如CO 2激光束的外科手术剂的探针和用于通过抽吸去除由外科手术产生的烟雾的除烟器。该探针没有用于产生激光束的功能组件，因此经济地足以在一次使用之后是一次性的。除烟器包括喷嘴和/或偏移吸入口，其被配置成通过手件从手部件的远端通过手持件在烟雾的流体流动路径上游的目标区域中的烟雾中产生电荷流。

3. 发明授权

US07228160B2 System, apparatus and method for inferring glucose levels within the peritoneum with implantable sensors 有权
标题翻译：用植入式传感器推测腹膜内葡萄糖水平的系统，装置和方法
公开(公告)号：US07228160B2
公开(公告)日：2007-06-05
申请号：US10703152
申请日：2003-11-06
申请人： LeVoy Golden Haight , Kevin W. Gordon , James L. Sorenson
发明人： LeVoy Golden Haight , Kevin W. Gordon , James L. Sorenson
IPC分类号： A61B5/00
CPC分类号： C12Q1/54
摘要： A glucose sensor assembly useful in patient systems includes an oxygen sensor from which glucose levels in the vicinity of the peritoneal cavity may be inferred. The sensor assembly may be associated with electronics, such as any or all of a DC power supply, an LED source of blue light, a photoreceptor for red light, a CPU, and transceiver, by a direct percutaneous connection. Alternatively they may be associated transdermally with the sensor and some of the electronics being located subdurally. Insulin infusion means are contemplated to respond manually or mechanically to information from the sensors through the CPU. Mechanical response may be automatic. Infusion means may be located subdurally. It is contemplated that the present invention enable revitalization or replacement of fluorescing compounds and glucose oxidase within the sensor assembly.
摘要翻译：可用于患者系统的葡萄糖传感器组件包括氧传感器，可从其中推断出腹膜腔附近的葡萄糖水平。传感器组件可以通过直接经皮连接与诸如DC电源，蓝光的LED源，红光的感光体，CPU和收发器之类的电子设备相关联。或者，它们可以与传感器经皮相关联，并且一些电子器件位于硬膜下。胰岛素注入装置被设想为通过CPU手动或机械地响应来自传感器的信息。机械响应可能是自动的。输注手段可能位于硬膜下。预期本发明能够在传感器组件内振兴或替换荧光化合物和葡萄糖氧化酶。

4. 发明授权

US06965791B1 Implantable biosensor system, apparatus and method 失效
标题翻译：植入式生物传感器系统，装置和方法
公开(公告)号：US06965791B1
公开(公告)日：2005-11-15
申请号：US10401224
申请日：2003-03-26
申请人： Robert W. Hitchcock , James L. Sorenson
发明人： Robert W. Hitchcock , James L. Sorenson
IPC分类号： A61B5/00 , A61B5/05 , G01N20060101 , G01N27/26
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/6852 , A61B2560/045
摘要： An implantable biosensor assembly and system includes an enzymatic sensor probe from which subcutaneous and interstitial glucose levels may be inferred. The assembly may be associated by direct percutaneous connection with electronics, such as for signal amplification, sensor polarization, and data download, manipulation, display, and storage. The biosensor comprises a miniature probe characterized by lateral flexibility and tensile strength and has large electrode surface area for increased sensitivity. Irritation of tissues surrounding the probe is minimized due to ease of flexibility and small cross section of the sensor. Foreign body reaction is diminished due to a microscopically rough porous probe surface.
摘要翻译：植入式生物传感器组件和系统包括酶传感器探针，可以推断皮下和间质葡萄糖水平。组件可以通过与电子设备的直接经皮连接相关联，例如用于信号放大，传感器极化以及数据下载，操纵，显示和存储。生物传感器包括微型探头，其特征在于侧向柔性和拉伸强度，并且具有大的电极表面积以增加灵敏度。由于传感器的灵活性和横截面小，容易刺激探针周围的组织。由于显微镜粗糙的多孔探针表面，异物反应减弱。

5. 发明授权

US5972317A Composition and method for treating diseased nails 失效
标题翻译：用于治疗患病指甲的组合物和方法
公开(公告)号：US5972317A
公开(公告)日：1999-10-26
申请号：US130132
申请日：1998-08-06
申请人： James L. Sorenson , Robert V. Petersen
发明人： James L. Sorenson , Robert V. Petersen
IPC分类号： A01L15/00 , A61K8/66 , A61K9/00 , A61K9/70 , A61K31/4418 , A61K38/43 , A61K47/46 , A61P17/00 , A61P17/16 , A61Q3/00 , A61K7/04
CPC分类号： A61K47/46 , A01L15/00 , A61K31/4418 , A61K8/66 , A61K9/0014 , A61K9/70 , A61Q3/00 , Y10S514/946
摘要： A nail-permeable medication means is disclosed for delivering a medicament through nails, claws, hoofs, or other similar hardened tissue of dermal derivation. The nail-permeable medication means includes a proteolytic enzyme component which facilitates permeation of substances through the hardened nail or keratin tissue, and also includes a medicament component selected to treat a specific disease. The nail-permeable medication means is particularly useful for treating onychomycosis of the fingernail or toenail, and avoids the need for more drastic therapeutic modalities, such as removal of the nail.
摘要翻译：公开了一种指甲渗透性药物装置，用于通过指甲，爪，蹄或其他类似的硬皮组织进行皮肤衍生递送药物。指甲渗透性药物装置包括促进物质通过硬化的指甲或角蛋白组织渗透的蛋白水解酶组分，并且还包括选择用于治疗特定疾病的药物组分。指甲可渗透的药物装置特别可用于治疗指甲或脚趾甲的甲真菌病，并且避免需要更严重的治疗方式，例如去除指甲。

6. 发明授权

US5242474A Dual mode laser smoke evacuation system with sequential filter monitor and vacuum compensation 失效
标题翻译：具有连续过滤器监视器和真空补偿的双模式激光吸烟系统
公开(公告)号：US5242474A
公开(公告)日：1993-09-07
申请号：US974378
申请日：1992-11-10
申请人： Royce Herbst , James L. Sorenson
发明人： Royce Herbst , James L. Sorenson
IPC分类号： A61B18/00 , B01D46/46 , B08B15/04
CPC分类号： A61B18/00 , B01D46/46 , B08B15/04 , A61B2218/008
摘要： A surgical laser smoke evacuation system includes a sensor positioned at the surgical site to determine the need for evacuation. A vacuum pump draws smoke from the site through a system of conduits, including an in line filter. The filter tends to become clogged over time. A sensor determines changes in the pressure drop across the filter, and is connected to a control mechanism which adjusts the speed of the vacuum pump to maintain an approximately constant flow across the filter.
摘要翻译：手术激光排烟系统包括位于手术部位的传感器，以确定需要撤离。真空泵通过管道系统（包括在线过滤器）从现场抽取烟雾。过滤器随时间变得堵塞。传感器确定过滤器上的压降的变化，并且连接到控制机构，该控制机构调整真空泵的速度以保持过滤器上的大致恒定的流量。

7. 发明授权

US4224943A Cannula and method for bidirectional blood flow 失效
标题翻译：插管和双向血流方法
公开(公告)号：US4224943A
公开(公告)日：1980-09-30
申请号：US6053
申请日：1979-01-24
申请人： Robert H. Johnson , Dixon A. Ford , Gordon S. Reynolds , James L. Sorenson
发明人： Robert H. Johnson , Dixon A. Ford , Gordon S. Reynolds , James L. Sorenson
IPC分类号： A61M5/158 , A61M5/00
CPC分类号： A61M5/1582 , A61M2025/0031
摘要： A cannula and method for bidirectional blood flow, the cannula being constructed so as to provide a bifurcated flow path, each branch of the flow path independently communicating through telescoping cannulae and a venipuncture needle initially projecting beyond the exterior cannula to facilitate venipuncture and thereafter being displaceable away from the venipuncture site to permit unobstructed simultaneous fluid flow in opposite directions through each of the bifurcated flow paths.
摘要翻译：一种用于双向血流的套管和方法，所述套管被构造成提供分叉的流动路径，所述流动路径的每个分支独立地通过伸缩套管连通，并且静脉穿刺针最初突出超过外部套管以便于静脉穿刺并且此后可移位远离静脉穿刺部位，以允许通过每个分叉流动路径在相反方向上畅通无阻地同时流动。

8. 发明授权

US4033345A Autologous transfusion filter system and method 失效
标题翻译：自体输血过滤系统及方法
公开(公告)号：US4033345A
公开(公告)日：1977-07-05
申请号：US651376
申请日：1976-01-21
申请人： James L. Sorenson , Karl A. Pannier, Jr. , Gordon S. Reynolds
发明人： James L. Sorenson , Karl A. Pannier, Jr. , Gordon S. Reynolds
IPC分类号： A61M1/00 , A61M1/02 , A61M1/36 , A61M5/14
CPC分类号： A61M1/3627 , A61M1/0011 , A61M1/0017 , A61M1/02 , Y10T137/3109
摘要： An autologous blood transfusion system having at least two interconnected blood receptacles and an associated filter assembly, the first receptacle being evacuated and connected to a suction device for aspirating blood. The second receptacle takes blood from the first by overcoming the vacuum in the first with a greater vacuum in the second without interrupting the ability of the suction device to simultaneously aspirate blood. The second receptacle may comprise a transfer bag for reinfusion into the patient or an infusion set may be connected to the second receptacle to permit simultaneous collection of the blood from the patient and infusion of the blood back into the patient. In either case, the second receptacle is selectively exposed to positive pressure to force blood through the filter assembly and expel the blood from the second receptacle into the transfer bag or patient. The method includes aspirating blood from the patient and collecting blood in the first receptacle. Blood is thereafter transferred to the second receptacle by increasing the vacuum in the second receptacle over the first receptacle without interrupting the ability of the suction device to simultaneously aspirate blood. Blood is then filtered by subjecting the blood within the second receptacle to positive fluid pressure which urges the blood through the filter assembly.
摘要翻译：一种自体输血系统，具有至少两个相互连接的血液接收器和相关联的过滤器组件，所述第一容器被抽真空并连接到用于抽吸血液的抽吸装置。第二个容器从第一容器中取出血液，在第二个容器中以较大的真空克服第一个真空，而不会中断抽吸装置同时抽吸血液的能力。第二容器可以包括用于输入到患者体内的输送袋，或者输注组件可连接到第二容器，以允许同时收集来自患者的血液并将血液输回到患者体内。在任一情况下，第二容器选择性地暴露于正压力以迫使血液通过过滤器组件，并将血液从第二容器排出到传送袋或患者体内。该方法包括从患者吸取血液并在第一容器中收集血液。此后，血液通过在第一容器上增加第二容器中的真空而转移到第二容器，而不会中断抽吸装置同时抽吸血液的能力。然后通过使第二容器内的血液经受通过过滤器组件推动血液的正的液体压力来过滤血液。

9. 发明授权

US4006745A Autologous transfusion system and method 失效
标题翻译：自体输血系统及方法
公开(公告)号：US4006745A
公开(公告)日：1977-02-08
申请号：US631584
申请日：1975-11-13
申请人： James L. Sorenson , Karl A. Pannier, Jr. , Gordon S. Reynolds
发明人： James L. Sorenson , Karl A. Pannier, Jr. , Gordon S. Reynolds
IPC分类号： A61M1/00 , A61M1/02 , A61M5/00
CPC分类号： A61M1/0011 , A61M1/0017 , A61M1/02
摘要： An autologous blood transfusion system comprising at least two interconnected blood receptacles, the first of which is evacuated and connected to a suction device for aspirating blood. The second receptacle takes blood from the first by overcoming the vacuum in the first with a greater vacuum in the second without interrupting the ability of the suction device to simultaneously aspirate blood. The second receptacle may comprise a transfer bag for reinfusion into the patient or an infusion set may be connected to the second receptacle to permit simultaneous collection of the blood from the patient and infusion of the blood back into the patient. In either case, the second receptacle is selectively exposed to positive pressure to expel the blood from the second receptacle into the transfer bag or patient. The method includes aspirating blood from the patient and collecting blood in the first receptacle. Blood is thereafter transferred to the second receptacle by increasing the vacuum in the second receptacle over the first receptacle without interrupting the ability of the suction device to simultaneously aspirate blood. Blood is then expelled from the second receptacle by subjecting the blood within the second receptacle to positive fluid pressure.
摘要翻译：一种自体输血系统，其包括至少两个相互连接的血液贮器，其中第一个被抽吸并连接到用于抽吸血液的抽吸装置。第二个容器从第一容器中取出血液，在第二个容器中以较大的真空克服第一个真空，而不会中断抽吸装置同时抽吸血液的能力。第二容器可以包括用于输入到患者体内的输送袋，或者输注组件可连接到第二容器，以允许同时收集来自患者的血液并将血液输回到患者体内。在任一情况下，第二容器选择性地暴露于正压力以将血液从第二容器排出到传送袋或患者体内。该方法包括从患者吸取血液并在第一容器中收集血液。此后，血液通过在第一容器上增加第二容器中的真空而转移到第二容器，而不会中断抽吸装置同时抽吸血液的能力。然后通过使第二容器内的血液受到正的流体压力而将血液从第二容器排出。

10. 发明授权

US07957907B2 Method for molecular genealogical research 有权
标题翻译：分子谱学研究方法
公开(公告)号：US07957907B2
公开(公告)日：2011-06-07
申请号：US10113901
申请日：2002-03-29
申请人： James L. Sorenson , Scott R. Woodward , Joel Myres , Natalie Myres, legal representative
发明人： James L. Sorenson , Scott R. Woodward , Joel Myres
IPC分类号： G01N33/48 , G06F19/00 , G01N31/00 , G06G7/48
CPC分类号： G06F19/22 , G06F19/14
摘要： A genealogical research and record keeping system and method for identifying commonalities in haplotypes and other genetic characteristics of two or more individual members of a biological sample. Chromosomal fragments identical by descent identify family ties between siblings, parents and children and ancestors and progeny across many generations. It is particularly useful in corroborating and improving the accuracy of genealogical data, and identifying previously unknown genetic relationships.
摘要翻译：用于确定生物样品中两个或更多个体成员的单元型和其他遗传特征的共同性的谱系研究和记录保存系统和方法。染色体片段通过血统相同识别兄弟姐妹，父母和孩子之间的亲缘关系，祖先和子代多代人之间的亲缘关系。它在确证和提高谱系数据的准确性以及识别以前未知的遗传关系方面特别有用。

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