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1. 发明申请

US20090268952A1 METHOD AND APPARATUS FOR AUTOMATICALLY DEVELOPING A HIGH PERFORMANCE CLASSIFIER FOR PRODUCING MEDICALLY MEANINGFUL DESCRIPTORS IN MEDICAL DIAGNOSIS IMAGING 有权
标题翻译：用于自动开发用于在医学诊断成像中生产医学意义描述符的高性能分类器的方法和装置
公开(公告)号：US20090268952A1
公开(公告)日：2009-10-29
申请号：US11721999
申请日：2005-12-13
申请人： James David Schaffer , Walid Ali , Larry Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicolas Francois Villain , Robert Randall Entrekin
发明人： James David Schaffer , Walid Ali , Larry Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicolas Francois Villain , Robert Randall Entrekin
IPC分类号： G06K9/00
CPC分类号： G06K9/6217
摘要： A method for determining the presence or absence of malignant features in medical images, wherein a plurality of base comparison or training images of various types of lesions taken of actual patient is examined by one or more image reading experts to create a first database array. Low-level features of each of the lesions in the same plurality of base comparisons or training images arc determined using one or more image processing algorithms to obtain a second database array set. The first and second database array set are combined to create a training database array set which is input to a learning system that discovers/learns a classifier that maps from a subset of the low-level features to the expert's evaluation in the first database array set. The classifier is used to determine the presence of a particular mid-level feature in an image of lesion in a patient based solely on the image.
摘要翻译：一种用于确定医学图像中恶性特征的存在或不存在的方法，其中由一个或多个图像读取专家检查由实际患者取得的各种类型的损伤的多个基础比较或训练图像以创建第一数据库阵列。使用一个或多个图像处理算法确定相同多个基本比较或训练图像中的每个病变的低级特征以获得第二数据库阵列集。组合第一和第二数据库阵列组以创建训练数据库阵列集合，其被输入到发现/学习从低级特征的子集映射到第一数据库阵列集合中的专家评估的分类器的学习系统。分类器用于仅基于图像来确定患者的病变图像中特定中级特征的存在。

2. 发明授权

US08805003B2 Device and method for localizing an object of interest in a subject 有权
标题翻译：用于本地化对象中的感兴趣对象的设备和方法
公开(公告)号：US08805003B2
公开(公告)日：2014-08-12
申请号：US12999393
申请日：2009-06-18
申请人： Nicolas Francois Villain , Cecile Anne Marie Picard , Nicolas Pierre Bruno Gogin
发明人： Nicolas Francois Villain , Cecile Anne Marie Picard , Nicolas Pierre Bruno Gogin
IPC分类号： G06K9/00
CPC分类号： A61B34/20 , A61B6/12 , A61B6/469 , A61B2034/2065 , A61B2090/376 , G06T7/38 , G06T7/73 , G06T2207/10124 , G06T2207/30021 , G06T2207/30048
摘要： A device for localization of an object of interest in a subject includes a registration unit for registering a 3D-representation of the subject having a plurality of segments corresponding to a plurality of structural regions of the subject, with a 2D-image. The registration unit is configured to define a plurality of areas in the image such that at least one area of the plurality of areas is associated with a respective region of the plurality of regions. A localization unit is configured to localize the object, and extract an indication of the object from the image by processing the image. The processing is limited to an object area of the plurality of areas which is associated with a predetermined object region.
摘要翻译：用于在被摄体中定位感兴趣对象的设备包括：注册单元，用于使用2D图像将具有对应于被摄体的多个结构区域的多个片段的被摄体的3D表示注册。注册单元被配置为定义图像中的多个区域，使得多个区域中的至少一个区域与多个区域的相应区域相关联。定位单元被配置为使对象本地化，并且通过处理图像来从图像提取对象的指示。处理限于与预定对象区域相关联的多个区域中的对象区域。

3. 发明授权

US09554728B2 Visualization for navigation guidance 有权
标题翻译：可视化导航指导
公开(公告)号：US09554728B2
公开(公告)日：2017-01-31
申请号：US14002368
申请日：2012-03-01
申请人： Robert Manzke , Patrick Etyngier , Pascal Yves Francois Cathier , Nicolas Francois Villain , Volker Rasche , Kawaldeep Singh Rhode
发明人： Robert Manzke , Patrick Etyngier , Pascal Yves Francois Cathier , Nicolas Francois Villain , Volker Rasche , Kawaldeep Singh Rhode
IPC分类号： G06K9/00 , A61B5/06 , A61B6/12 , A61B6/03 , A61B6/00
CPC分类号： A61B5/066 , A61B6/032 , A61B6/12 , A61B6/488 , A61B6/503 , A61B6/5235 , A61B90/37 , A61B2034/2065 , A61B2090/364 , A61B2090/376
摘要： The present invention relates to visualizing information of an object. In order to provide spatial information and in addition situation specific data to the user while ensuring an effective perceptibility, a method (110) is provided comprising the steps of: a) providing (112) pre-navigation data (114) of a region of interest of an object (22); wherein the pre-navigation data comprises spatial geometrical data (116) and a functional parameter surface (118) in correspondence to the spatial geometrical data; b) acquiring (120) live image data (122) of the region of interest; c) detecting (124) an element (126) in the live image data; d) determining (128) spatial relation (130) of the pre-navigation data and the live image data; e) determining (132)the position (134) of the detected element in the spatial geometrical data, which determining is based on the spatial relation, and computing (136) a predetermined related point of location (138) on the functional parameter surface; f) generating (140) a combination (142) of a simplified surface representation (144) of the region of interest, which simplified surface representation is based on a visualization of the functional parameter surface, and a marker (146) indicating the computed predetermined related point of location; and g) displaying (148) the combination as navigation guidance (150).
摘要翻译：本发明涉及可视化对象的信息。为了在确保有效的可感知性的同时向用户提供空间信息和附加情况特定数据，提供了一种方法（110），包括以下步骤：a）提供（112）前导数据（114）物体（22）的兴趣; 其中所述预导数据包括对应于所述空间几何数据的空间几何数据（116）和功能参数表面（118）; b）获取（120）感兴趣区域的实时图像数据（122）; c）在实况图像数据中检测（124）元素（126）; d）确定（128）前导数据和实时图像数据的空间关系（130）; e）确定（132）在所述空间几何数据中检测到的元素的位置（134），所述空间几何数据基于所述空间关系确定，并且计算（136）所述功能参数表面上的预定相关位置点（138）; f）产生（140）所述感兴趣区域的简化表面表示（144）的组合（142），所述简化表面表示基于所述功能参数表面的可视化，以及指示所计算的预定相关点位置; 以及g）将所述组合显示（148）作为导航指导（150）。

4. 发明申请

US20130336558A1 VISUALIZATION FOR NAVIGATION GUIDANCE 有权
标题翻译：可视化导航指导
公开(公告)号：US20130336558A1
公开(公告)日：2013-12-19
申请号：US14002368
申请日：2012-03-01
申请人： Robert Manzke , Patrick Etyngier , Pascal Yves Francois Cathier , Nicolas Francois Villain , Volker Rasche , Kawaldeep Singh Rhode
发明人： Robert Manzke , Patrick Etyngier , Pascal Yves Francois Cathier , Nicolas Francois Villain , Volker Rasche , Kawaldeep Singh Rhode
IPC分类号： A61B5/06
CPC分类号： A61B5/066 , A61B6/032 , A61B6/12 , A61B6/488 , A61B6/503 , A61B6/5235 , A61B90/37 , A61B2034/2065 , A61B2090/364 , A61B2090/376
摘要： The present invention relates to visualizing information of an object. In order to provide spatial information and in addition situation specific data to the user while ensuring an effective perceptibility, a method (110) is provided comprising the steps of: a) providing (112) pre-navigation data (114) spatial geometrical data (116) and a functional parameter surface (118) of a region of interest of an object (22); wherein the pre-navigation data comprises in correspondence to the spatial geometrical data; b) acquiring (120) live image data (122) of the region of interest; c) detecting (124) an element (126) in the live image data; d) determining (128) spatial relation (130) of the pre-navigation data and the live image data; e) determining (132)the position (134) of the detected element in the spatial geometrical data, which determining is based on the spatial relation, and computing (136) a predetermined related point of location (138) on the functional parameter surface; f) generating (140) a combination (142) of a simplified surface representation (144) of the region of interest, which simplified surface representation is based on a visualization of the functional parameter surface, and a marker (146) indicating the computed predetermined related point of location; and g) displaying (148) the combination as navigation guidance (150).
摘要翻译：本发明涉及可视化对象的信息。为了在确保有效的感知性的同时向用户提供空间信息和附加情况特定数据，提供了一种方法（110），包括以下步骤：a）提供（112）预导数据（114）空间几何数据 116）和物体（22）的感兴趣区域的功能参数表面（118）; 其中所述预导数据包括对应于所述空间几何数据; b）获取（120）感兴趣区域的实时图像数据（122）; c）在实况图像数据中检测（124）元素（126）; d）确定（128）前导数据和实时图像数据的空间关系（130）; e）确定（132）在所述空间几何数据中检测到的元素的位置（134），所述空间几何数据基于所述空间关系确定，并且计算（136）所述功能参数表面上的预定相关位置点（138）; f）产生（140）所述感兴趣区域的简化表面表示（144）的组合（142），所述简化表面表示基于所述功能参数表面的可视化，以及指示所计算的预定相关点位置; 以及g）将所述组合显示（148）作为导航指导（150）。

5. 发明申请

US20110085706A1 DEVICE AND METHOD FOR LOCALIZING AN OBJECT OF INTEREST IN A SUBJECT 有权
标题翻译：用于本地化对象中的兴趣对象的设备和方法
公开(公告)号：US20110085706A1
公开(公告)日：2011-04-14
申请号：US12999393
申请日：2009-06-18
申请人： Nicolas Francois Villain , Cecile Anne Marie Picard , Nicolas Pierre Bruno Gogin
发明人： Nicolas Francois Villain , Cecile Anne Marie Picard , Nicolas Pierre Bruno Gogin
IPC分类号： G06K9/00
CPC分类号： A61B34/20 , A61B6/12 , A61B6/469 , A61B2034/2065 , A61B2090/376 , G06T7/38 , G06T7/73 , G06T2207/10124 , G06T2207/30021 , G06T2207/30048
摘要： The present invention relates to a device, a method and a computer program which allow for the localization of an object of interest in a subject. The device includes a registration unit (25) for registering (120) a 3D-representation of the subject, which comprises a plurality of segments corresponding to a plurality of structural regions of the subject, with a 2D-image (200), wherein the registration unit is adapted for defining a plurality of areas (205, 210, 215) in the image such that at least one area of the plurality of areas is associated with a respective region of the plurality of regions, and a localization unit (30) for localizing (125) the object, extracting an indication of the object from the image by processing the image, wherein the processing is limited to an object area of the plurality of areas which is associated with a predetermined object region.
摘要翻译：本发明涉及允许感兴趣对象在对象中的本地化的装置，方法和计算机程序。所述装置包括注册单元（25），用于使用2D图像（200）来注册（120）包括与所述对象的多个结构区域对应的多个段的所述对象的3D表示，其中，注册单元适于在图像中定义多个区域（205,210,215），使得多个区域中的至少一个区域与多个区域的相应区域相关联，并且定位单元（30）用于对对象进行本地化（125），通过处理图像从图像中提取对象的指示，其中处理限于与预定对象区域相关联的多个区域中的对象区域。

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