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1. 发明授权

US09251593B2 Medical imaging system and a method for segmenting an object of interest 有权
标题翻译：医学成像系统和分割感兴趣对象的方法
公开(公告)号：US09251593B2
公开(公告)日：2016-02-02
申请号：US10550344
申请日：2004-03-18
申请人： Nicolas Villain , Claude Cohen-Bacrie , Jean-Michel LaGrange , Claire Levrier , Robert Randall Entrekin
发明人： Nicolas Villain , Claude Cohen-Bacrie , Jean-Michel LaGrange , Claire Levrier , Robert Randall Entrekin
IPC分类号： A61B5/05 , G06T7/00
CPC分类号： G06T7/0081 , A61B2576/00 , G06F19/00 , G06T7/11 , G06T7/155 , G06T2207/10132 , G06T2207/20132 , G06T2207/20152 , G06T2207/30004
摘要： The invention concerns a medical imaging system comprising means (4) of segmenting a region of interest around an object of interest within a volume of 3D data (3DV). The system according to the invention comprises means (5) of calculating a sub-regions map (CSR) within the segmented region (RS) and correction means (6) intended to exclude sub-regions of the segmented region by means of said sub-regions map (CSR). The correction can be made automatically or manually by means of control means (7) enabling a user to select the sub-regions to be excluded. Display means (3) make it possible to display a 2D representation (2DR) of the volume of 3D data (3DV) and the segmented region (RS, RS′) at various stages of the processing.
摘要翻译：本发明涉及一种医学成像系统，其包括在3D数据量（3DV）的范围内分割感兴趣对象周围的感兴趣区域的装置（4）。根据本发明的系统包括计算分段区域（RS）内的子区域映射（CSR）的装置（5）和旨在通过所述子区域（RS）排除分段区域的子区域的校正装置（6）区域地图（CSR）。可以通过控制装置（7）自动或手动进行校正，使得用户能够选择要排除的子区域。显示装置（3）使得可以在处理的各个阶段显示3D数据量（3DV）和分割区域（RS，RS'）的2D表示（2DR）。

2. 发明申请

US20130131511A1 ULTRASONIC SHEAR WAVE IMAGING WITH FOCUSED SCANLINE BEAMFORMING 审中-公开
标题翻译：超声剪切波成像与聚焦扫描光束
公开(公告)号：US20130131511A1
公开(公告)日：2013-05-23
申请号：US13511307
申请日：2010-11-15
申请人： Roy Beck Peterson , Yan Shi , Hua Xie , Jean-Luc Robert , Vijay Shamdasani , Robert Randall Entrekin , Anna Teresa Fernandez
发明人： Roy Beck Peterson , Yan Shi , Hua Xie , Jean-Luc Robert , Vijay Shamdasani , Robert Randall Entrekin , Anna Teresa Fernandez
IPC分类号： A61B8/08 , A61B8/00 , A61B8/14
CPC分类号： A61B8/485 , A61B5/0048 , A61B8/08 , A61B8/085 , A61B8/14 , A61B8/463 , A61B8/5223 , G01S7/52022 , G01S7/52042 , G01S7/52071 , G01S7/52095 , G01S15/8984
摘要： An ultrasonic diagnostic imaging system produces an image of shear wave velocities by transmitting push pulses to generate shear waves. A plurality of tracking lines are transmitted and echoes received by a focusing beamformer adjacent to the location of the push pulses. The tracking lines are sampled in a time-interleaved manner. The echo data acquired along each tracking line is processed to determine the time of peak tissue displacement caused by the shear waves at points along the tracking line, and the times of peaks at adjacent tracking lines compared to compute a local shear wave velocity. The resultant map of shear wave velocity values is color-coded and displayed over an anatomical image of the region of interest.
摘要翻译：超声波诊断成像系统通过传递推动脉冲来产生剪切波速度的图像以产生剪切波。多个跟踪线被发送，并且由聚焦波束形成器接收的与推送脉冲位置相邻的回波。跟踪线以时间交织的方式进行采样。处理沿着每个跟踪线获取的回波数据，以确定由沿着跟踪线的点处的剪切波引起的峰组织位移的时间，以及相邻跟踪线的峰值时间，以计算局部剪切波速度。所得到的剪切波速度值的映射是彩色编码的，并显示在感兴趣区域的解剖图像上。

3. 发明申请

US20110105900A1 Transducer Unit Incorporating an Acoustic Coupler 审中-公开
标题翻译：传感器单元结合一个声耦合器
公开(公告)号：US20110105900A1
公开(公告)日：2011-05-05
申请号：US11570171
申请日：2005-06-09
申请人： Robert Randall Entrekin
发明人： Robert Randall Entrekin
IPC分类号： A61B8/14
CPC分类号： A61B8/4455 , A61B8/0825 , A61B8/4209 , A61B8/4281
摘要： The present invention relates to a transducer unit for an ultrasonic breast imaging system, in which an acoustic coupler is employed which comprises a frame in which a transducer is mounted. The frame is open at one end, and a surface of the transducer is exposed at the open end. The frame and exposed transducer surface are put under compression against the surface of a compression plate with a gasket, or similar, providing a fluid-tight seal therebetween. A thin layer of acoustic couplant is provided between the transducer surface and the compression plate. The frame defines a chamber around the nonexposed surface of the transducer, the chamber housing an acoustic couplant.
摘要翻译：本发明涉及一种用于超声乳房成像系统的换能器单元，其中采用声耦合器，其包括安装换能器的框架。框架在一端打开，传感器的表面在开口端露出。框架和暴露的换能器表面被压在压缩板的表面上，垫圈或类似物在其间提供流体密封的密封。在传感器表面和压缩板之间提供薄层的声耦合剂。框架围绕换能器的未暴露的表面限定一个腔室，该腔室容纳声学耦合剂。

4. 发明申请

US20110079083A1 EXTENDED FIELD OF VIEW ULTRASONIC IMAGING WITH GUIDED EFOV SCANNING 有权
标题翻译：扩展视野超声波成像与指导EFOV扫描
公开(公告)号：US20110079083A1
公开(公告)日：2011-04-07
申请号：US12995194
申请日：2009-06-02
申请人： Yangmo Yoo , James Jago , Jing-Ming Jong , Robert Randall Entrekin , Martin Anderson , Lars Jonas Olsson
发明人： Yangmo Yoo , James Jago , Jing-Ming Jong , Robert Randall Entrekin , Martin Anderson , Lars Jonas Olsson
IPC分类号： G01N29/00
CPC分类号： G01S7/52065 , A61B8/4245 , A61B8/483 , G01S7/52073 , G01S7/52074 , G01S15/8993
摘要： An ultrasonic diagnostic imaging system produces an extended field of view (EFOV) image. A 3D imaging probe is moved along the skin of a patient above the anatomy which is to be included in the EFOV image. As the probe is moved, images are acquired from a plurality of differently oriented image planes such as a sagittal plane and a transverse plane. As the probe is moved the image data of successive planes of one of the orientations is compared to estimate the motion of the probe. These motion estimates are used to position a succession of images acquired in one of the orientations accurately with respect to each other in an EFOV display format. The motion estimates are also used to display a graphic on the display screen which indicates the progress of the scan to the user as the probe is being moved. The progress may be indicated in terms of probe velocity, distance traveled, or the path traversed by the moving probe.
摘要翻译：超声波诊断成像系统产生扩展视野（EFOV）图像。 3D成像探头沿着要包括在EFOV图像中的解剖结构上方的患者的皮肤移动。当探针移动时，从多个不同取向的图像平面（例如矢状面和横向平面）获取图像。随着探头被移动，比较一个方向的连续平面的图像数据以估计探针的运动。这些运动估计用于以EFOV显示格式相对于彼此精确地定位在一个取向中获取的一系列图像。运动估计还用于在显示屏幕上显示图形，其指示当探头被移动时向用户扫描的进展。可以根据探头速度，行进距离或移动探头穿过的路径来指示进度。

5. 发明授权

US08539838B2 Extended field of view ultrasonic imaging with a two dimensional array probe 有权
标题翻译：扩展视野超声波成像与二维阵列探针
公开(公告)号：US08539838B2
公开(公告)日：2013-09-24
申请号：US12995191
申请日：2009-06-02
申请人： Yangmo Yoo , James Jago , Jing-Ming Jong , Robert Randall Entrekin , Martin Anderson , Lars Jonas Olsson
发明人： Yangmo Yoo , James Jago , Jing-Ming Jong , Robert Randall Entrekin , Martin Anderson , Lars Jonas Olsson
IPC分类号： G01N29/00 , A61B8/00
CPC分类号： G01S7/52065 , A61B8/4245 , A61B8/483 , G01S7/5205 , G01S7/52073 , G01S7/52074 , G01S15/8993
摘要： An ultrasonic diagnostic imaging system produces an extended field of view (EFOV) image. A 3D imaging probe is moved along the skin of a patient above the anatomy which is to be included in the EFOV image. As the probe is moved, images are acquired from a plurality of differently oriented image planes such as a sagittal plane and a transverse plane. As the probe is moved the image data of successive planes of one of the orientations is compared to estimate the motion of the probe. These motion estimates are used to position a succession of images acquired in one of the orientations accurately with respect to each other in an EFOV display format. The display format may be either a 2D EFOV image or a 3D EFOV image.
摘要翻译：超声波诊断成像系统产生扩展视野（EFOV）图像。 3D成像探头沿着要包括在EFOV图像中的解剖结构上方的患者的皮肤移动。当探针移动时，从多个不同取向的图像平面（例如矢状面和横向平面）获取图像。随着探头被移动，比较一个方向的连续平面的图像数据以估计探针的运动。这些运动估计用于以EFOV显示格式相对于彼此精确地定位在一个取向中获取的一系列图像。显示格式可以是2D EFOV图像或3D EFOV图像。

6. 发明授权

US10368843B2 Ultrasonic shear wave imaging with focused scanline beamforming 有权
公开(公告)号：US10368843B2
公开(公告)日：2019-08-06
申请号：US13511307
申请日：2010-11-15
申请人： Roy Beck Peterson , Yan Shi , Hua Xie , Jean-Luc Robert , Vijay Shamdasani , Robert Randall Entrekin , Anna Teresa Ferandez
发明人： Roy Beck Peterson , Yan Shi , Hua Xie , Jean-Luc Robert , Vijay Shamdasani , Robert Randall Entrekin , Anna Teresa Ferandez
IPC分类号： A61B5/00 , A61B8/00 , A61B8/08 , A61B8/14 , G01S7/52 , G01S15/89
摘要： An ultrasonic diagnostic imaging system produces an image of shear wave velocities by transmitting push pulses to generate shear waves. A plurality of tracking lines are transmitted and echoes received by a focusing beamformer adjacent to the location of the push pulses. The tracking lines are sampled in a time-interleaved manner. The echo data acquired along each tracking line is processed to determine the time of peak tissue displacement caused by the shear waves at points along the tracking line, and the times of peaks at adjacent tracking lines compared to compute a local shear wave velocity. The resultant map of shear wave velocity values is color-coded and displayed over an anatomical image of the region of interest.

7. 发明授权

US08852107B2 Extended field of view ultrasonic imaging with guided EFOV scanning 有权
标题翻译：扩展视野超声波成像与引导EFOV扫描
公开(公告)号：US08852107B2
公开(公告)日：2014-10-07
申请号：US12995194
申请日：2009-06-02
申请人： Yangmo Yoo , James Jago , Jing-Ming Jong , Robert Randall Entrekin , Martin Anderson , Lars Jonas Olsson
发明人： Yangmo Yoo , James Jago , Jing-Ming Jong , Robert Randall Entrekin , Martin Anderson , Lars Jonas Olsson
IPC分类号： G01S7/52 , G01S15/89
CPC分类号： G01S7/52065 , A61B8/4245 , A61B8/483 , G01S7/52073 , G01S7/52074 , G01S15/8993
摘要： An ultrasonic diagnostic imaging system produces an extended field of view (EFOV) image. A 3D imaging probe is moved along the skin of a patient above the anatomy which is to be included in the EFOV image. As the probe is moved, images are acquired from a plurality of differently oriented image planes such as a sagittal plane and a transverse plane. As the probe is moved the image data of successive planes of one of the orientations is compared to estimate the motion of the probe. These motion estimates are used to position a succession of images acquired in one of the orientations accurately with respect to each other in an EFOV display format. The motion estimates are also used to display a graphic on the display screen which indicates the progress of the scan to the user as the probe is being moved. The progress may be indicated in terms of probe velocity, distance traveled, or the path traversed by the moving probe.
摘要翻译：超声波诊断成像系统产生扩展视野（EFOV）图像。 3D成像探头沿着要包括在EFOV图像中的解剖结构上方的患者的皮肤移动。当探针移动时，从多个不同取向的图像平面（例如矢状面和横向平面）获取图像。随着探头被移动，比较一个方向的连续平面的图像数据以估计探针的运动。这些运动估计用于以EFOV显示格式相对于彼此精确地定位在一个取向中获取的一系列图像。运动估计还用于在显示屏幕上显示图形，其指示当探头被移动时向用户扫描的进展。可以根据探头速度，行进距离或移动探头穿过的路径来指示进度。

8. 发明申请

US20110079082A1 EXTENDED FIELD OF VIEW ULTRASONIC IMAGING WITH A TWO DIMENSIONAL ARRAY PROBE 有权
标题翻译：扩展视野超声波成像与两维阵列探测
公开(公告)号：US20110079082A1
公开(公告)日：2011-04-07
申请号：US12995191
申请日：2009-06-02
申请人： Yangmo Yoo , James Jago , Jing-Ming Jong , Robert Randall Entrekin , Martin Anderson , Lars Jonas Olsson
发明人： Yangmo Yoo , James Jago , Jing-Ming Jong , Robert Randall Entrekin , Martin Anderson , Lars Jonas Olsson
IPC分类号： G01N29/00
CPC分类号： G01S7/52065 , A61B8/4245 , A61B8/483 , G01S7/5205 , G01S7/52073 , G01S7/52074 , G01S15/8993
摘要： An ultrasonic diagnostic imaging system produces an extended field of view (EFOV) image. A 3D imaging probe is moved along the skin of a patient above the anatomy which is to be included in the EFOV image. As the probe is moved, images are acquired from a plurality of differently oriented image planes such as a sagittal plane and a transverse plane. As the probe is moved the image data of successive planes of one of the orientations is compared to estimate the motion of the probe. These motion estimates are used to position a succession of images acquired in one of the orientations accurately with respect to each other in an EFOV display format. The display format may be either a 2D EFOV image or a 3D EFOV image.
摘要翻译：超声波诊断成像系统产生扩展视野（EFOV）图像。 3D成像探头沿着要包括在EFOV图像中的解剖结构上方的患者的皮肤移动。当探针移动时，从多个不同取向的图像平面（例如矢状面和横向平面）获取图像。随着探头被移动，比较一个方向的连续平面的图像数据以估计探针的运动。这些运动估计用于以EFOV显示格式相对于彼此精确地定位在一个方向中获取的一系列图像。显示格式可以是2D EFOV图像或3D EFOV图像。

9. 发明申请

US20090268952A1 METHOD AND APPARATUS FOR AUTOMATICALLY DEVELOPING A HIGH PERFORMANCE CLASSIFIER FOR PRODUCING MEDICALLY MEANINGFUL DESCRIPTORS IN MEDICAL DIAGNOSIS IMAGING 有权
标题翻译：用于自动开发用于在医学诊断成像中生产医学意义描述符的高性能分类器的方法和装置
公开(公告)号：US20090268952A1
公开(公告)日：2009-10-29
申请号：US11721999
申请日：2005-12-13
申请人： James David Schaffer , Walid Ali , Larry Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicolas Francois Villain , Robert Randall Entrekin
发明人： James David Schaffer , Walid Ali , Larry Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicolas Francois Villain , Robert Randall Entrekin
IPC分类号： G06K9/00
CPC分类号： G06K9/6217
摘要： A method for determining the presence or absence of malignant features in medical images, wherein a plurality of base comparison or training images of various types of lesions taken of actual patient is examined by one or more image reading experts to create a first database array. Low-level features of each of the lesions in the same plurality of base comparisons or training images arc determined using one or more image processing algorithms to obtain a second database array set. The first and second database array set are combined to create a training database array set which is input to a learning system that discovers/learns a classifier that maps from a subset of the low-level features to the expert's evaluation in the first database array set. The classifier is used to determine the presence of a particular mid-level feature in an image of lesion in a patient based solely on the image.
摘要翻译：一种用于确定医学图像中恶性特征的存在或不存在的方法，其中由一个或多个图像读取专家检查由实际患者取得的各种类型的损伤的多个基础比较或训练图像以创建第一数据库阵列。使用一个或多个图像处理算法确定相同多个基本比较或训练图像中的每个病变的低级特征以获得第二数据库阵列集。组合第一和第二数据库阵列组以创建训练数据库阵列集合，其被输入到发现/学习从低级特征的子集映射到第一数据库阵列集合中的专家评估的分类器的学习系统。分类器用于仅基于图像来确定患者的病变图像中特定中级特征的存在。

10. 发明申请

US20080255452A1 Methods and Apparatus For Performing Enhanced Ultrasound Diagnostic Breast Imaging 审中-公开
标题翻译：用于进行增强超声诊断乳腺成像的方法和装置
公开(公告)号：US20080255452A1
公开(公告)日：2008-10-16
申请号：US11576214
申请日：2005-09-22
申请人： Robert Randall Entrekin
发明人： Robert Randall Entrekin
IPC分类号： A61B8/14
CPC分类号： A61B8/483 , A61B8/0825
摘要： A method for performing enhanced ultrasound diagnostic breast imaging includes using first and second compression plates (62,64) configured for receiving and compressing a breast between the same. The breast extends from a chest wall (118) of a patient at a proximate end to a nipple at a distal end. Portions of the breast proximate the nipple and proximate lateral edges of the breast are in non-contact with the second compression plate during breast compression. An ultrasound transducer array (68) moves along a path to scan the breast, the ultrasound transducer array being disposed adjacent a side of the second plate (64) opposite the breast. Image data representative of the breast is acquired as the ultrasound transducer array (68) traverses the path. Acquiring image data includes using electronic beam steering with the ultrasound transducer array to acquire image data in either or both (i) a portion (116) of the breast proximate the chest wall and (ii) a portion of the breast in non-contact with the second plate (122).
摘要翻译：用于执行增强超声诊断乳房成像的方法包括使用被配置为在其间接收和压缩乳房的第一和第二压缩板（62,64）。乳房在近端从患者的胸壁（118）延伸到远端的乳头。乳房附近的乳房部分和乳房附近的侧边缘在乳房压缩期间与第二压缩板不接触。超声换能器阵列（68）沿着路径移动以扫描乳房，超声换能器阵列邻近与乳房相对的第二板（64）的一侧设置。当超声波换能器阵列（68）穿过路径时，获取表示乳房的图像数据。获取图像数据包括使用电子束转向与超声换能器阵列获取图像数据，以在（i）靠近胸壁的乳房的一部分（116）和（ii）乳房的一部分（116）中接触第二板（122）。

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