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    • 4. 发明授权
    • Catalyzed water-soluble/dispersible reactive derivatives of polyimido compounds for modifying proteinaceous substrates
    • 用于改性蛋白质底物的聚酰亚胺化合物的催化水溶性/可分散的活性衍生物
    • US06306378B1
    • 2001-10-23
    • US09287900
    • 1999-04-07
    • Jacob J. GuthSamuel A. Vona, Jr.John S. ThomaidesAnn C. Savoca
    • Jacob J. GuthSamuel A. Vona, Jr.John S. ThomaidesAnn C. Savoca
    • A61K711
    • A61Q5/12A61K8/41A61K8/418A61K8/46A61K8/463A61K8/4913A61K8/4926A61K8/8164A61K8/84A61K8/88A61K2800/43A61K2800/57A61K2800/94A61Q3/00A61Q5/00A61Q5/02A61Q5/10A61Q17/04A61Q19/00
    • This invention relates to a two-part system useful for treating proteinaceous substrates. The two-part system has a first part comprising a water-soluble/dispersible reactive polyimido compound and a second part comprising a nucleophilic catalytic agent. The polyimido compounds may be selected from the group consisting of polysuccinimide compounds, polyglutimide compounds, and copolymers of thereof. The polyimido compound may also comprise a functionalizing moiety that provides functionality to the polyimido compound and is preferably derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates; and a water-solubilizing/dispersing moiety that provides water-solubility and/or water-dispersibility to the polyimido compound and is preferably derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates. The nucleophilic catalytic agent serves to catalyze nuclephilic substitution of the polyimido compound by the proteinaceous substrate. The invention also pertains to a method for treating a proteinaceous substrate with the two-part system and to a composition comprising a mixture of the polyimido compound and the nucleophilic catalytic agent.
    • 本发明涉及可用于处理蛋白质底物的两部分系统。 两部分系统具有包含水溶性/分散性反应性聚酰亚胺化合物的第一部分和包含亲核催化剂的第二部分。 聚酰亚胺化合物可以选自聚琥珀酰亚胺化合物,聚戊二酰亚胺化合物及其共聚物。 聚酰亚胺化合物还可以包含向聚亚胺化合物提供官能团的官能化部分,并且优选衍生自选自胺,醇,酚,硫醇和羧酸酯的亲核部分; 以及向聚酰亚胺化合物提供水溶性和/或水分散性的水溶性/分散部分,并且优选衍生自选自胺,醇,酚,硫醇和羧酸盐的亲核部分。 亲核催化剂用于催化蛋白质底物对聚酰亚胺化合物的亲核取代。 本发明还涉及用两部分系统处理蛋白质底物的方法以及包含聚酰亚胺化合物和亲核催化剂的混合物的组合物。
    • 6. 发明授权
    • Seed coating compositions for low temperature applications
    • 用于低温应用的种皮涂料组合物
    • US06329319B1
    • 2001-12-11
    • US09382434
    • 1999-08-25
    • Christine PuglisiJacob J. Guth
    • Christine PuglisiJacob J. Guth
    • A01N2526
    • A01C1/06
    • A seed coating composition for low temperature applications, said seed coating composition comprising at least one polymer having a Tg of −60° C. to 20° C., provided that the Tg of the polymer is less than or equal to the seed surface temperature at the time of application. The seed coating compositions of the invention provide a matrix which entraps active ingredients and improves seedling survival by maintaining the active ingredient on the surface of the seed for a period of time. The seed coating also increases the safety of using an active ingredient by reducing operator exposure and environmental release. In addition, the seed coating composition is resistant to cracking and flaking even when the seed coating composition is applied at a temperature of less than 20° C. Moreover, the seed coating composition improves the uniformity of seed size and shape which is advantageous to mechanical planting techniques.
    • 用于低温应用的种子包衣组合物,所述种子包衣组合物包含至少一种Tg为-60℃至20℃的聚合物,条件是聚合物的Tg小于或等于种子表面温度 在申请时。 本发明的种子包衣组合物提供了通过将种子表面上的活性成分维持一段时间来捕获活性成分并改善幼苗存活的基质。 种子涂层还通过减少操作者的暴露和环境释放来增加使用活性成分的安全性。 此外,种子包衣组合物即使在低于20℃的温度下施用种子包衣组合物也耐龟裂和剥落。此外,种子包衣组合物改善种子大小和形状的均匀性,这有利于机械 种植技术。
    • 9. 发明授权
    • Hair and skin conditioning agents and methods
    • 头发和皮肤调理剂及方法
    • US4978526A
    • 1990-12-18
    • US249632
    • 1988-09-26
    • Bruce W. GessleinJacob J. GuthGilbert R. MintzGale M. ReinhartLaurence R. Smith
    • Bruce W. GessleinJacob J. GuthGilbert R. MintzGale M. ReinhartLaurence R. Smith
    • A61K8/41A61K8/42A61Q5/12
    • A61Q5/12A61K8/416A61K8/42Y10S514/846Y10S514/847Y10S514/848Y10S514/873
    • Alkyl or alkylamido dimethyl 2,3-dihydroxypropyl ammonium salts may be used in hair and skin conditioning compositions and methods to provide improved manageability, static control, and ease of wet and dry combing when applied to hair, particularly human scalp hair, and smooth and lubricated surfaces with pleasant after-feel when applied in topical conditioner compositions to the human skin. The hair conditioning formulations may include styling, cleaning and rinsing compositions such as gels, mousses, sprays, lotions, glazes and shampoos, while the skin conditioning compositions may include moisturizing creams and lotions, bath oils, liquid cleaners, body mousses or bath gels, as well as alcoholic or hydroalcoholic astringents, toners, pre-electric shave conditioners, after-bath splashes and fragrance products. A preferred quaternary according to the invention is oleamidoproyl dimethyl 2,3-dihydroxypropyl ammonium chloride, which forms exceptionally stable, clear, dilutable gels.
    • 烷基或烷基酰氨基二甲基2,3-二羟基丙基铵盐可以用于头发和皮肤调理组合物和方法中,以提供改善的可管理性,静态控制,以及当应用于头发,特别是人类头皮头发时湿和干梳理的容易性,以及平滑和 润滑表面,当在局部调理剂组合物中施用于人皮肤时具有愉悦的后感。 头发调理制剂可以包括造型,清洁和漂洗组合物如凝胶,摩丝,喷雾剂,洗剂,釉料和洗发剂,而皮肤调理组合物可以包括保湿霜和洗剂,沐浴油,液体清洁剂,身体摩丝或浴凝胶, 以及酒精或水醇收敛剂,调色剂,预电动剃须调理剂,洗澡后的香水和香水产品。 根据本发明优选的季铵盐是油酰胺基丙基二甲基2,3-二羟基丙基氯化铵,其形成非常稳定,透明的可稀释凝胶。