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1. 发明授权

US07706090B2 Diaphragm device 有权
标题翻译：隔膜装置
公开(公告)号：US07706090B2
公开(公告)日：2010-04-27
申请号：US11330386
申请日：2006-01-12
申请人： Jörg Steinert , Thomas Mehner , Volker Gerstner
发明人： Jörg Steinert , Thomas Mehner , Volker Gerstner
IPC分类号： G02B5/22
CPC分类号： G02B5/005 , G01J3/02 , G01J3/0229
摘要： A diaphragm device with which individual wavelengths or ranges of wavelengths in the path of a beam of spectrally dispersed light can be suppressed. Such a diaphragm device comprises at least one array of diaphragms, wherein the individual diaphragms of the array are arranged in a definite relation to each other and may be coupled in the path of the beam and each diaphragm of the array in the coupled state is arranged in a given relation to an individual wavelength or a range of wavelengths.
摘要翻译：可以抑制光谱分散光束的光路中的各波长或波长范围的光阑装置。这种隔膜装置包括至少一个隔膜阵列，其中阵列的各个隔膜彼此以一定的关系布置，并且可以在梁的路径中耦合，并且联接状态的阵列的每个隔膜被布置与波长或波长范围有关。

2. 发明授权

US07933083B2 Diaphragm device 有权
标题翻译：隔膜装置
公开(公告)号：US07933083B2
公开(公告)日：2011-04-26
申请号：US12767965
申请日：2010-04-27
申请人： Jörg Steinert , Thomas Mehner , Volker Gerstner
发明人： Jörg Steinert , Thomas Mehner , Volker Gerstner
IPC分类号： G02B5/22
CPC分类号： G02B5/005 , G01J3/02 , G01J3/0229
摘要： A diaphragm device with which individual wavelengths or ranges of wavelengths in the path of a beam of spectrally dispersed light can be suppressed. Such a diaphragm device comprises at least one array of diaphragms, wherein the individual diaphragms of the array are arranged in a definite relation to each other and may be coupled in the path of the beam and each diaphragm of the array in the coupled state is arranged in a given relation to an individual wavelength or a range of wavelengths.
摘要翻译：可以抑制光谱分散光束的光路中的各波长或波长范围的光阑装置。这种隔膜装置包括至少一个隔膜阵列，其中阵列的各个隔膜彼此以一定的关系布置，并且可以在梁的路径中耦合，并且联接状态的阵列的每个隔膜被布置与波长或波长范围有关。

3. 发明申请

US20070146900A1 Diaphragm device 有权
标题翻译：隔膜装置
公开(公告)号：US20070146900A1
公开(公告)日：2007-06-28
申请号：US11330386
申请日：2006-01-12
申请人： Jorg Steinert , Thomas Mehner , Volker Gerstner
发明人： Jorg Steinert , Thomas Mehner , Volker Gerstner
IPC分类号： G02B9/00 , G02B9/08
CPC分类号： G02B5/005 , G01J3/02 , G01J3/0229
摘要： A diaphragm device with which individual wavelengths or ranges of wavelengths in the path of a beam of spectrally dispersed light can be suppressed. Such a diaphragm device comprises at least one array of diaphragms, wherein the individual diaphragms of the array are arranged in a definite relation to each other and may be coupled in the path of the beam and each diaphragm of the array in the coupled state is arranged in a given relation to an individual wavelength or a range of wavelengths.
摘要翻译：可以抑制光谱分散光束的光路中的各波长或波长范围的光阑装置。这种隔膜装置包括至少一个隔膜阵列，其中阵列的各个隔膜彼此以一定的关系布置，并且可以在梁的路径中耦合，并且联接状态的阵列的每个隔膜被布置与波长或波长范围有关。

4. 发明申请

US20060000984A1 Method for increasing the spectral and spatial resolution of detectors 有权
公开(公告)号：US20060000984A1
公开(公告)日：2006-01-05
申请号：US11182465
申请日：2005-07-15
申请人： Ralf Wolleschensky , Gunter Moehler , Volker Gerstner
发明人： Ralf Wolleschensky , Gunter Moehler , Volker Gerstner
IPC分类号： G01J1/58 , F21V9/16
CPC分类号： G02B21/0004 , G02B21/16
摘要： A method of optical detection of characteristic quantities of an illuminated specimen comprising detecting a signal that is backscattered, reflected and/or fluoresced and/or transmitted from the specimen by a spatially resolving detector wherein radiation coming from the specimen is imaged on the detector, shifting the position of the radiation which is measured in a spatially resolved manner relative to the detector and determining intermediate values by an algorithm from the signals measured in different shifts for purposes of increasing the spatial resolution of the detector. An arrangement for performing the method is also disclosed.

5. 发明授权

US06741346B1 Method for detecting fluorescence phenomena in microscope 有权
标题翻译：荧光显微镜检测方法
公开(公告)号：US06741346B1
公开(公告)日：2004-05-25
申请号：US09869317
申请日：2001-12-21
申请人： Volker Gerstner , Ralf Wolleschensky
发明人： Volker Gerstner , Ralf Wolleschensky
IPC分类号： G01J330
CPC分类号： G01N21/6408
摘要： Process for detecting the phenomenon of fluorescence in a microscope, wherein the sample is irradiated by a modulated and/or pulsed laser light source, and the fluorescence is detected at least in two different phase positions of the detector.
摘要翻译：用于在显微镜中检测荧光现象的方法，其中样品被调制和/或脉冲激光光源照射，并且在检测器的至少两个不同的相位位置检测荧光。

6. 发明申请

US20050063051A1 Arrangement for the direct inout coupling of a laser, particularly of a short-pulse laser 审中-公开
标题翻译：用于激光器，特别是短脉冲激光器的直接入射耦合的布置
公开(公告)号：US20050063051A1
公开(公告)日：2005-03-24
申请号：US10888186
申请日：2004-07-09
申请人： Ralph Lange , Stefan Wilhelm , Volker Gerstner , Roland Scheler , Michael Goelles , Joerg-Michael Funk
发明人： Ralph Lange , Stefan Wilhelm , Volker Gerstner , Roland Scheler , Michael Goelles , Joerg-Michael Funk
IPC分类号： G02B21/18 , G02B21/00 , G02B21/06
CPC分类号： G02B21/002 , G02B21/06
摘要： An arrangement for direct input coupling of a laser, preferably of a short-pulse laser, for nonlinear sample excitation which is located outside of the microscope housing, into the beam path of a laser scanning microscope (LSM), comprising a housing in which is integrated an adjusting laser that can be coupled into the microscope beam path by beam splitters, wherein the housing is advantageously integrated so as to be insertable in the scan module of the LSMA, and a beam splitter for the direct coupling laser has high transmission in the direction of the objective and, further, partial transmission for back-reflections of the adjusting laser coming from the specimen for adjusting the overlapping of the adjusting laser and direct coupling laser.
摘要翻译：用于直接输入耦合激光扫描显微镜（LSM）的激光扫描显微镜（LSM）的光束路径中的用于将位于显微镜外壳之外的非线性样品激发的短脉冲激光器的激光直接输入耦合的装置，其中，集成了可以通过分束器耦合到显微镜光束路径中的调节激光器，其中壳体有利地集成以便可插入到LSMA的扫描模块中，并且用于直接耦合激光器的分束器在并且进一步地，用于调整来自测试样品的调节激光器的反射反射的部分透射以调节调节激光器和直接耦合激光器的重叠。

7. 发明申请

US20080043786A1 Tunable light source for use in microscopy 审中-公开
标题翻译：可调光源用于显微镜
公开(公告)号：US20080043786A1
公开(公告)日：2008-02-21
申请号：US11889906
申请日：2007-08-17
申请人： Stefan Wilhelm , Volker Gerstner , Peter Westphal , Dieter Huhse
发明人： Stefan Wilhelm , Volker Gerstner , Peter Westphal , Dieter Huhse
IPC分类号： H01S3/10
CPC分类号： G02B21/0032 , H01S5/06258 , H01S5/1215 , H01S5/36
摘要： A tunable lighting source, especially for a microscope, which contains a laser, in which the lighting source delivers spectrally variable and spatially coherent radiation. The tunable lighting source is based on a structured substrate coated with a laser medium, the structured substrate provided with the laser medium having a geometrically variable structure and delivering spatially coherent radiation by energy excitation.
摘要翻译：可调光源，特别是对于包含激光器的显微镜，其中照明源提供光谱可变和空间相干辐射。可调谐照明源基于涂覆有激光介质的结构化衬底，该结构化衬底设置有具有几何可变结构的激光介质，并且通过能量激发传送空间相干辐射。

8. 发明授权

US06947133B2 Method for increasing the spectral and spatial resolution of detectors 失效
标题翻译：增加检测器的光谱和空间分辨率的方法
公开(公告)号：US06947133B2
公开(公告)日：2005-09-20
申请号：US09924268
申请日：2001-08-07
申请人： Ralf Wolleschensky , Gunter Moehler , Volker Gerstner
发明人： Ralf Wolleschensky , Gunter Moehler , Volker Gerstner
IPC分类号： G01Q60/18 , G02B21/00 , G02B21/16 , G01J3/30 , G01N21/00
CPC分类号： G02B21/0004 , G02B21/16
摘要： A method of optical detection of characteristic quantities of an illuminated specimen comprising detecting a signal that is backscattered, reflected and/or fluoresced and/or transmitted from the specimen by a spatially resolving detector wherein radiation coming from the specimen is imaged on the detector, shifting the position of the radiation which is measured in a spatially resolved manner relative to the detector and determining intermediate values by an algorithm from the signals measured in different shifts for purposes of increasing the spatial resolution of the detector. An arrangement for performing the method is also disclosed.
摘要翻译：一种光学检测照明样本的特征量的方法，包括通过空间分辨检测器检测从样品反向散射，反射和/或发射和/或发射和/或发射的信号，其中来自样品的辐射被成像在检测器上，移位以相对于检测器的空间分辨方式测量的辐射的位置，并且为了增加检测器的空间分辨率，由不同位移测量的信号通过算法确定中间值。还公开了一种用于执行该方法的装置。

9. 发明授权

US07420674B2 Method and arrangement for analyzing samples 有权
标题翻译：分析样品的方法和布置
公开(公告)号：US07420674B2
公开(公告)日：2008-09-02
申请号：US10514673
申请日：2003-05-14
申请人： Volker Gerstner , Joerg Lindenau
发明人： Volker Gerstner , Joerg Lindenau
IPC分类号： G01J3/30
CPC分类号： G01N21/6458 , G01N21/6428 , G02B21/0064 , G02B21/0076 , G02B21/008
摘要： A method and/or arrangement for the analysis of fluorescing samples in an image-generating microscope system, preferably a laser scanning microscope, wherein the sample is scanned point-by-point or line-by-line in at least one surface section and a dispersive splitting of the radiation coming from the sample is carried out during the scanning, wherein the split radiation is detected by at least one line of detector elements in a wavelength-dependent manner, a selection of two-dimensional or three-dimensional sample parts which correspond to pre-stored two-dimensional or three-dimensional geometric objects or the like is carried out based on the recorded and stored intensity distribution of at least one of these detection elements and/or at least one other detection element for the radiation reflected from the sample by image processing, and an analysis of the spectral signature and/or spatial spectral sequence is carried out for at least a portion of these sample regions with respect to the fluorescence markers arranged thereon.
摘要翻译：一种用于在图像生成显微镜系统（优选激光扫描显微镜）中分析荧光样品的方法和/或装置，其中在至少一个表面部分逐点或逐行扫描样品，在扫描期间进行来自样品的辐射的分散分裂，其中分裂辐射由波长相关方式的至少一行检测器元件检测，二维或三维样品部分的选择，其中对应于预先存储的二维或三维几何对象等，基于这些检测元件中的至少一个的记录和存储的强度分布和/或用于从通过图像处理的样本，以及对于这些样本区域的至少一部分，相对于t进行光谱特征和/或空间光谱序列的分析 o布置在其上的荧光标记。

10. 发明授权

US07271897B2 Method for increasing the spectral and spatial resolution of detectors 有权
标题翻译：增加检测器的光谱和空间分辨率的方法
公开(公告)号：US07271897B2
公开(公告)日：2007-09-18
申请号：US11182465
申请日：2005-07-15
申请人： Ralf Wolleschensky , Gunter Moehler , Volker Gerstner
发明人： Ralf Wolleschensky , Gunter Moehler , Volker Gerstner
IPC分类号： G01J3/30 , G01N21/00
CPC分类号： G02B21/0004 , G02B21/16
摘要： A method of optical detection of characteristic quantities of an illuminated specimen comprising detecting a signal that is backscattered, reflected and/or fluoresced and/or transmitted from the specimen by a spatially resolving detector wherein radiation coming from the specimen is imaged on the detector, shifting the position of the radiation which is measured in a spatially resolved manner relative to the detector and determining intermediate values by an algorithm from the signals measured in different shifts for purposes of increasing the spatial resolution of the detector. An arrangement for performing the method is also disclosed.
摘要翻译：一种光学检测照明样本的特征量的方法，包括通过空间分辨检测器检测从样品反向散射，反射和/或发射和/或发射和/或发射的信号，其中来自样品的辐射被成像在检测器上，移位以相对于检测器的空间分辨方式测量的辐射的位置，并且为了增加检测器的空间分辨率，由不同位移测量的信号通过算法确定中间值。还公开了一种用于执行该方法的装置。

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