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1. 发明授权

US5244501A Apparatus for chemical vapor deposition 失效
标题翻译：化学气相沉积设备
公开(公告)号：US5244501A
公开(公告)日：1993-09-14
申请号：US733373
申请日：1991-07-22
申请人： Izumi Nakayama , Akitoshi Suzuki , Hiroyuki Nawa , Motohiro Kaneko , Yoshiro Kusumoto , Kazuo Takakuwa , Tetsuya Ikuta
发明人： Izumi Nakayama , Akitoshi Suzuki , Hiroyuki Nawa , Motohiro Kaneko , Yoshiro Kusumoto , Kazuo Takakuwa , Tetsuya Ikuta
IPC分类号： C23C16/44 , C23C16/455 , C23C16/48 , H01L21/768
CPC分类号： C23C16/45519 , C23C16/455 , C23C16/481 , H01L21/76879
摘要： An apparatus for a chemical vapor deposition in which at least one substrate which has partially an insulating film on the surface thereof is disposed in a pressure reduced reaction chamber, the reaction chamber is provided with a nozzle for feeding a reactive gas into the reaction chamber, and a light source is provided for emitting a light beam to heat the substrate. The combination of substrate heating source using infrared rays and a laminarized jet of reactive gas is utilized for maintaining the selectivity, facilitating the thin film forming reaction, and improving the high reproducibility and controllability.
摘要翻译：一种用于化学气相沉积的装置，其中至少一个在其表面上具有部分绝缘膜的基板设置在减压反应室中，反应室设置有用于将反应性气体进料到反应室中的喷嘴，并且提供用于发射光束以加热衬底的光源。使用红外线的基板加热源和反应气体的层流喷射的组合用于保持选择性，促进薄膜形成反应，提高高再现性和可控性。

2. 发明授权

US4924807A Apparatus for chemical vapor deposition 失效
标题翻译：化学气相沉积设备
公开(公告)号：US4924807A
公开(公告)日：1990-05-15
申请号：US77621
申请日：1987-07-24
申请人： Izumi Nakayama , Akitoshi Suzuki , Hiroyuki Nawa , Motohiro Kaneko , Yoshiro Kusumoto , Kazuo Takakuwa , Tetsuya Ikuta
发明人： Izumi Nakayama , Akitoshi Suzuki , Hiroyuki Nawa , Motohiro Kaneko , Yoshiro Kusumoto , Kazuo Takakuwa , Tetsuya Ikuta
IPC分类号： C23C16/44 , C23C16/455 , C23C16/48 , H01L21/768
CPC分类号： C23C16/45519 , C23C16/455 , C23C16/481 , H01L21/76879
摘要： An apparatus for a chemical vapor deposition in which at least one substrate which has partially an insulating film on the surface thereof is disposed in a pressure reduced reaction chamber, the reaction chamber is provided with a nozzle for feeding a reactive gas into the reaction chamber, and a light source is provided for emitting a light beam to heat the substrate. The apparatus has provision for feeding a second gas opposite the substrate to put the reactive gas in the vicinity of the substrate surface into laminar flow. The combination of substrate heating source using infrared rays and the laminarized jet of reactive gas is utilized for maintaining the selectivity, facilitating the thin film forming reaction, and obtaining improved high reproducibility and controllability.
摘要翻译：一种用于化学气相沉积的装置，其中至少一个在其表面上具有部分绝缘膜的基板设置在减压反应室中，反应室设置有用于将反应性气体进料到反应室中的喷嘴，并且提供用于发射光束以加热衬底的光源。该装置具有用于供给与基板相对的第二气体以将反应气体放置在基板表面附近的层流中。使用红外线的基板加热源与反应气体的层流喷射的组合用于维持选择性，促进薄膜形成反应，并获得改进的高再现性和可控性。

3. 发明授权

US5125360A Vacuum processing apparatus 失效
标题翻译：真空加工设备
公开(公告)号：US5125360A
公开(公告)日：1992-06-30
申请号：US299935
申请日：1989-01-23
申请人： Izumi Nakayama , Akitoshi Suzuki , Hiroyuki Nawa , Motohiro Kaneko
发明人： Izumi Nakayama , Akitoshi Suzuki , Hiroyuki Nawa , Motohiro Kaneko
IPC分类号： C23C16/509 , C23C16/54 , H01J37/32 , H01L21/67
CPC分类号： H01J37/32862 , C23C16/5096 , C23C16/54 , H01J37/32623 , H01L21/67
摘要： A vacuum processing apparatus in which a DC bias to be produced on the surfaces of substrates which are to be processed in a vacuum chamber can be mechanically and easily controlled by adjusting the position of a susceptor in respect to an electrode body, and the susceptor and other components in the vacuum chamber can be easily cleaned while maintaining a desired evacuated condition and a desired processing performance in the vacuum chamber.
摘要翻译：一种真空处理装置，其中在真空室中待处理的基板的表面上产生的直流偏压可以通过调节基座相对于电极体的位置而机械地和容易地控制，并且基座和真空室中的其它部件可以容易地清洁，同时保持真空室中所需的抽真空条件和期望的加工性能。

4. 发明授权

US4902531A Vacuum processing method and apparatus 失效
标题翻译：真空加工方法及装置
公开(公告)号：US4902531A
公开(公告)日：1990-02-20
申请号：US113117
申请日：1987-10-27
申请人： Izumi Nakayama , Akitoshi Suzuki , Hiroyuki Nawa , Motohiro Kaneko
发明人： Izumi Nakayama , Akitoshi Suzuki , Hiroyuki Nawa , Motohiro Kaneko
IPC分类号： C23C16/509 , C23C16/54 , H01J37/32 , H01L21/67
CPC分类号： H01J37/32862 , C23C16/5096 , C23C16/54 , H01J37/32623 , H01L21/67
摘要： A vacuum processing method and apparatus in which a DC bias to be produced on the surfaces of substrates which are to be processed in a vacuum chamber can be mechanically and easily controlled by adjusting the position of a susceptor in respect to an electrode body, and the susceptor and other components in the vacuum chamber can be easily cleaned while maintaining a desired evacuated condition and a desired processing performance in the vacuum chamber.
摘要翻译：一种真空处理方法和装置，其中通过调节基座相对于电极体的位置，可以机械地和容易地控制在真空室中待处理的基板的表面上产生的直流偏压，并且真空室中的基座和其他部件可以容易地清洁，同时保持真空室中所需的抽真空条件和期望的加工性能。

5. 发明申请

US20060167026A1 Antipsychotic molecular-targeting epithelial growth factor receptor 审中-公开
标题翻译：抗精神病药分子靶向上皮生长因子受体
公开(公告)号：US20060167026A1
公开(公告)日：2006-07-27
申请号：US10540989
申请日：2004-01-05
申请人： Hiroyuki Nawa , Makoto Mizuno
发明人： Hiroyuki Nawa , Makoto Mizuno
IPC分类号： A61K31/517
CPC分类号： A61K31/517 , A61K31/47 , A61K31/4709 , A61K31/4741 , A61K31/496 , A61K31/519
摘要： The purpose of this invention is to provide an agent useful for prevention and/or treatment of psychosis, schizophrenia and cognitive impairments. To solve this problem, this invention provides epidermal growth factor receptor inhibitors as therapeutic agents for psychosis, schizophrenia and cognitive impairments.
摘要翻译：本发明的目的是提供一种可用于预防和/或治疗精神病，精神分裂症和认知障碍的药剂。为了解决这个问题，本发明提供表皮生长因子受体抑制剂作为精神病，精神分裂症和认知障碍的治疗剂。

6. 发明申请

US20060099593A1 Method of diagnosing integration dysfunction syndrome using blood 审中-公开
标题翻译：使用血液诊断综合功能障碍综合征的方法
公开(公告)号：US20060099593A1
公开(公告)日：2006-05-11
申请号：US10528433
申请日：2003-09-26
申请人： Hiroyuki Nawa , Toshiyuki Someya , Tatsuyuki Muratake , Meiko Kawamura
发明人： Hiroyuki Nawa , Toshiyuki Someya , Tatsuyuki Muratake , Meiko Kawamura
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： C12Q1/6883 , C12Q2600/158 , G01N33/5091 , G01N33/6896 , G01N2800/302
摘要： An object of the present invention is. to provide an objective method for diagnosis of schizophrenia using gene expression in mononuclear cells of peripheral blood as an index, and this invention provide a method for diagnosing whether a test subject suffers from schizophrenia or not. The method according to this invention is a method for diagnosing whether a test subject suffers from schizophrenia or not, the method comprising the steps of; obtaining mononuclear cells in blood containing nucleic acid from said subject, measuring the content of at least one nucleic acid selected from the group consisting of nucleic acid(s) (containing its fragment and a nucleic acid complementary to the nucleic acid) defining gene(s) exhibiting altered expression by occurrence of schizophrenia or nucleic acid(s) (containing its fragment and a nucleic acid complementary to the nucleic acid) defining gene(s) exhibiting altered expression by progression of schizophrenia in said mononuclear cells, and determining alteration of the quantified level(s) of the gene(s) in said test subject is statistically significant in comparison with the quantified level(s) of said nucleic acid(s) defining gene(s) exhibiting altered expression by occurrence of schizophrenia or said nucleic acid(s) defining gene(s) exhibiting altered expression by progression of schizophrenia in healthy subjects or schizophrenic patients, thereby diagnosing whether said subject is suffering from schizophrenia or not.
摘要翻译：本发明的目的是。以使用外周血单核细胞中的基因表达作为指标提供用于诊断精神分裂症的客观方法，本发明提供一种诊断受试者是否患有精神分裂症的方法。根据本发明的方法是用于诊断测试对象是否患有精神分裂症的方法，所述方法包括以下步骤：获得来自所述受试者的含有血液的核酸中的单核细胞，测量选自核酸（含有其与核酸互补的核苷酸）的至少一种核酸的含量，所述核酸定义基因）通过发生精神分裂症或核酸（含有其与核酸互补的核酸）表现出改变的表达，所述基因通过所述单核细胞中精神分裂症的进展表现出改变的表达，并且确定与所述定义的基因的定义水平相比，所述测试受试者中的基因的定量水平与通过发生精神分裂症或所述核酸显示改变的表达的基因的定量水平相比是统计学显着的定义通过健康受试者或精神分裂症患者的精神分裂症进展表现出改变的基因，由此诊断所述受试者是否患有精神分裂症？

7. 发明授权

US5830857A Method of treating epilepsy 失效
标题翻译：治疗癫痫的方法
公开(公告)号：US5830857A
公开(公告)日：1998-11-03
申请号：US502348
申请日：1995-07-14
申请人： Josette Fran.cedilla.oise Carnahan , Antoine Depaulis , Paul Feltz , Yves Larmet , Christian Marescaux , Hiroyuki Nawa
发明人： Josette Fran.cedilla.oise Carnahan , Antoine Depaulis , Paul Feltz , Yves Larmet , Christian Marescaux , Hiroyuki Nawa
IPC分类号： A61K38/00 , A61K38/18 , C12P21/06 , C12N15/00 , C07K3/00
CPC分类号： A61K38/185
摘要： A method is described for the therapeutic use of brain-derived neurotrophic factor (BDNF) to treat epilepsy.
摘要翻译：描述了用于治疗性使用脑源性神经营养因子（BDNF）治疗癫痫的方法。

8. 发明授权

US06433019B1 Neurotrophic factor secretion promoters 失效
标题翻译：神经营养因子分泌促进剂
公开(公告)号：US06433019B1
公开(公告)日：2002-08-13
申请号：US09601186
申请日：2000-07-28
申请人： Hiroyuki Nawa
发明人： Hiroyuki Nawa
IPC分类号： A61K3141
CPC分类号： A61K31/5377 , A61K31/00 , A61K31/15 , A61K31/16 , A61K31/198 , A61K31/21 , A61K31/34
摘要： The present invention relates to a neurotrophic factor secretagogue, in particular, to a BDNF (brain-derived neurotrophic factor) secretagogue, which comprises as an active ingredient an NO donor. The medicament of the present invention promotes the secretion of neurotrophic factors from mammalian central neural cells. Thus, the medicament of the present invention, i.e., NO donor, is possibly applicable to the treatment of diseases caused by neutrotrophic factors, for example, neurodegenerative diseases, and is expected to exhibit the efficacious effects thereon. Also, the present invention provides a novel medication for neurodegenerative diseases.
摘要翻译：本发明涉及神经营养因子促分泌素，特别涉及BDNF（脑源性神经营养因子）促分泌素，其包含作为活性成分的NO供体。本发明的药物促进哺乳动物中枢神经细胞分泌神经营养因子。因此，本发明的药物即NO供体可能适用于治疗由中性营养因子引起的疾病，例如神经变性疾病，并且预期其对其有显着的效果。另外，本发明提供了用于神经变性疾病的新型药物。

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