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1. 发明授权

US4565718A Process and apparatus for coating the surfaces of containers with a material 失效
标题翻译：用材料涂覆容器表面的方法和设备
公开(公告)号：US4565718A
公开(公告)日：1986-01-21
申请号：US685218
申请日：1984-12-26
申请人： Iwao Katsuyama , Aijiro Okuzumi
发明人： Iwao Katsuyama , Aijiro Okuzumi
IPC分类号： B05C5/00 , B05C13/02 , B05D1/30 , C03C17/00 , B05D1/02
CPC分类号： C03C17/005 , B05C13/025 , B05C5/002 , B05D1/30 , Y10S118/03 , Y10S118/04
摘要： Disclosed is a process and an apparatus for coating with a material a plurality of containers transported consecutively, in which after the completion of coating with the material flowing down of the uppermost container of the containers being transported vertically, the subsequent container becomes the new uppermost container which will be subject to next coating with the material.
摘要翻译：公开了一种用连续输送的多个容器涂覆材料的方法和装置，其中在由垂直运送的容器的最上层的容器流下的材料的涂覆完成之后，随后的容器成为新的最上面的容器这将随着材料的下一次涂覆。

2. 发明申请

US20060160063A1 Method of screening physilogically active substance 审中-公开
标题翻译：物理活性物质筛选方法
公开(公告)号：US20060160063A1
公开(公告)日：2006-07-20
申请号：US10526369
申请日：2003-09-05
申请人： Iwao Katsuyama , Tsutomu Arakawa , Masao Tokunaga , Tadashi Yamamoto
发明人： Iwao Katsuyama , Tsutomu Arakawa , Masao Tokunaga , Tadashi Yamamoto
IPC分类号： C12Q1/18 , C12N1/18 , C12Q1/00
CPC分类号： C12Q1/025 , G01N2333/39
摘要： The present invention relates to a method of screening a physiologically active substance, comprising the steps of (1) contacting a transformed yeast with a test sample, wherein the transformed yeast is capable of expressing a heterogeneous protein, and shows a change in a growing state in an expression state of the protein as compared to that in a non-expression state of the protein; (2) culturing the yeast under conditions that the protein is capable of being expressed; and (3) measuring the growing state of the yeast, wherein the physiologically active substance is judged to be present in the test sample in a case where the growth of the yeast is lowered or improved in the presence of the test sample as compared to that in the absence of the test sample as a control; an yeast to be used in the method; a physiologically active substance obtainable by the method of screening as defined above; and a kit for screening a physiologically active substance, comprising the yeast as defined above.
摘要翻译：本发明涉及筛选生理活性物质的方法，包括以下步骤：（1）将转化的酵母与测试样品接触，其中转化的酵母能够表达异质蛋白质，并显示生长状态的变化与蛋白质的非表达状态相比，处于蛋白质的表达状态; （2）在能够表达蛋白质的条件下培养酵母; 和（3）测量酵母的生长状态，其中在测试样品存在下酵母生长降低或改善的情况下，判定生理活性物质存在于测试样品中在没有测试样本作为对照的情况下; 在该方法中使用的酵母; 通过如上定义的筛选方法可获得的生理活性物质; 和用于筛选生理活性物质的试剂盒，其包含如上定义的酵母。

3. 发明授权

US06924413B2 Experimental animals for evaluation of therapeutic effects on corneal epithelial damages 失效
标题翻译：用于评估角膜上皮损伤的治疗效果的实验动物
公开(公告)号：US06924413B2
公开(公告)日：2005-08-02
申请号：US10043366
申请日：2002-01-10
申请人： Iwao Katsuyama
发明人： Iwao Katsuyama
IPC分类号： A01K67/00 , A01K67/027 , A61B3/10 , A61K45/00 , A61P27/02 , G01N33/15 , G01N33/48 , G01N33/50
CPC分类号： A01K67/027 , A01K67/00 , A01K2227/107 , A01K2227/30 , A01K2267/03
摘要： This invention provides experimental animals suffering corneal epithelial damages, such as dry eye, and methods of using the same to assay a variety of compounds for evaluating the therapeutic effect on the disease, and medicine selected using the method, wherein the corneal epithelial damage is induced by the steps of: using a water-absorbing material having a physical state selected from powder, solution, gel, jelly and tablet, and contacting the absorbing materials with the ocular cornea to generate a difference in osmotic pressure between the inside and outside of ocular corneal epithelium cells.
摘要翻译：本发明提供了患有角膜上皮损伤的实验动物，例如干眼症，以及使用该实验动物测定各种化合物以评估对该疾病的治疗效果的方法，以及使用该方法选择的药物，其中诱导角膜上皮损伤通过以下步骤：使用具有选自粉末，溶液，凝胶，果冻和片剂的物理状态的吸水材料，并使吸收材料与眼角膜接触以产生眼内和外侧之间的渗透压差角膜上皮细胞。

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