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1. 发明申请

US20050238581A1 Dynamic hepatic recycling glucose tolerance test 审中-公开
标题翻译：动态肝循环葡萄糖耐量试验
公开(公告)号：US20050238581A1
公开(公告)日：2005-10-27
申请号：US11060640
申请日：2005-02-16
申请人： Irwin Kurland , W. N. Lee , Mohammed Saad , Jun Xu
发明人： Irwin Kurland , W. N. Lee , Mohammed Saad , Jun Xu
IPC分类号： A61B20060101 , A61K49/00 , C12Q1/54 , G01N33/00 , G01N33/53 , G01N37/00
CPC分类号： G01N33/564 , G01N2800/042
摘要： Systems and methods are described providing a hepatic recycling glucose tolerance test for the diagnosis of types and subtypes of diabetes mellitus and other hyperglycemic or hypoglycemic conditions. A method is also provided for screening candidate drugs for treating various types of abnormal glucose metabolism and to monitor whether the course of treatment is effective. The method also allows the correlation of gene activity, hormone and metabolite levels with glucose flux and recycling and an assessment of the degree of hepatic insulin resistance. The method utilizes a preferably non-radioactive stable labeled glucose to asses the relative rates of carbon flow in the liver and provides a hepatic recycling constant that is a measure of the relative rate of glucose recycling. The labeled glucose may be introduced to the patient orally, intravenously or by intraperitoneal administration for the desired effect.
摘要翻译：描述了系统和方法，其提供用于诊断糖尿病和其他高血糖或低血糖病症的类型和亚型的肝循环葡萄糖耐量试验。还提供了用于筛选用于治疗各种异常葡萄糖代谢的候选药物并监测治疗过程是否有效的方法。该方法还允许基因活性，激素和代谢物水平与葡萄糖通量和回收率的关系以及肝胰岛素抵抗程度的评估。该方法利用优选非放射性稳定标记的葡萄糖来评估肝脏中碳流的相对速率，并提供作为葡萄糖再循环相对速率的量度的肝循环常数。标记的葡萄糖可以口服，静脉内或通过腹膜内给药以期望的效果被引入患者。

2. 发明申请

US20060142139A1 Heavy metal oxide thin films active and passive planar waveguide and optical devices 审中-公开
标题翻译：重金属氧化物薄膜有源和无源平面波导和光学器件
公开(公告)号：US20060142139A1
公开(公告)日：2006-06-29
申请号：US10515824
申请日：2003-05-27
申请人： Mohammed Saad
发明人： Mohammed Saad
IPC分类号： C03C13/04
CPC分类号： C03C13/042 , C03C13/048 , C03C17/23 , C03C25/1061 , C03C2217/23
摘要： The purpose of the invention is heavy metal oxide thin films and their applications. These thin films will serve to produce doped and undoped planar wave-guides and planar lightwave circuit (PLC) for passive and active optical devices (amplifier, laser, filter, multiplexer, attenuators and . . . ). These thin films present low loss, good chemical and thermal stability and wide optical transmission window, high solubility of all rare earth ions and transition metals ions . . . . They can be deposited on different substrates.
摘要翻译：本发明的目的是重金属氧化物薄膜及其应用。这些薄膜将用于产生无源和有源光学器件（放大器，激光器，滤波器，多路复用器，衰减器等）的掺杂和未掺杂的平面波导和平面光波电路（PLC）。这些薄膜具有低损耗，良好的化学和热稳定性和宽的光学透射窗，所有稀土离子和过渡金属离子的溶解度高。。。。它们可以沉积在不同的基底上。

3. 发明授权

US5342809A Process for the synthesis of fluoride glass by the sol - gel method and optical fibre produced from the fluoride glass obtained according to this process 失效
标题翻译：通过溶胶 - 凝胶法合成氟化玻璃的方法和由根据该方法获得的氟化物玻璃制成的光纤
公开(公告)号：US5342809A
公开(公告)日：1994-08-30
申请号：US43781
申请日：1993-04-06
申请人： Marcel Poulain , Mohammed Saad
发明人： Marcel Poulain , Mohammed Saad
IPC分类号： C03B37/016 , C03B8/00 , C03B8/02 , C03C1/00 , C03C3/32 , C03C13/04 , G02B6/00
CPC分类号： C03C3/325 , C03C1/006 , C03C13/042
摘要： The present invention relates to a process for the synthesis of fluoride glass by the sol-gel method.The object of the invention is to synthesize an impurity-free fluoride glass.This object is achieved with the aid of a process having stages consisting of preparing a wet oxygenated gel from precursors containing all the cations constituting said fluoride glass, hydrolyzing said gel, drying said gel and in which the process is characterized in that it also comprises the stage consisting of treating said oxygenated gel by a fluorinating agent in the vapour phase, at a temperature below the glass crystallization point.This process more particularly makes it possible to produce fluoride glass for optical fibres.
摘要翻译：本发明涉及通过溶胶 - 凝胶法合成氟化物玻璃的方法。本发明的目的是合成无杂质氟化物玻璃。该目的借助于具有以下步骤的方法来实现，该方法包括由含有构成所述氟化物玻璃的所有阳离子的前体制备湿氧化凝胶，水解所述凝胶，干燥所述凝胶，其中该方法的特征在于它还包括在玻璃结晶点以下的温度下，通过氟化剂在气相中处理所述含氧凝胶。该方法更具体地使得可以生产用于光纤的氟化物玻璃。

4. 发明申请

US20100285320A1 Amorphous thin films and method of manufacturing same 审中-公开
标题翻译：非晶薄膜及其制造方法
公开(公告)号：US20100285320A1
公开(公告)日：2010-11-11
申请号：US12078895
申请日：2008-04-08
申请人： Mohammed Saad
发明人： Mohammed Saad
IPC分类号： C09D1/00 , C03C13/04 , B32B17/06 , B32B9/00
CPC分类号： C03C13/042 , C03C1/008 , C03C13/048 , C03C17/02 , C03C17/23 , C03C25/1061 , C03C2203/36 , C03C2217/23 , C03C2218/113 , G02B2207/109
摘要： The present invention relates to amorphous thin films and methods of manufacturing the same. These amorphous thin films contain zirconium oxide (ZrO2), preferably at a concentration of at least 30 mol %, and other metal oxides and have surprisingly good mechanical and optical properties. In some embodiments of the present invention, the thin films may be further processed to obtain fluorinated glasses containing the same metal elements as the metal oxides.
摘要翻译：本发明涉及无定形薄膜及其制造方法。这些非晶态薄膜含有优选浓度至少为30摩尔％的氧化锆（ZrO 2）和其它金属氧化物，具有惊人的良好的机械和光学性能。在本发明的一些实施方案中，可以进一步处理薄膜以获得含有与金属氧化物相同的金属元素的氟化玻璃。

5. 发明申请

US20100095706A1 Method for manufacturing optical fibers and optical fiber performs 审中-公开
标题翻译：制造光纤和光纤的方法
公开(公告)号：US20100095706A1
公开(公告)日：2010-04-22
申请号：US12588568
申请日：2009-10-20
申请人： Mohammed Saad
发明人： Mohammed Saad
IPC分类号： C03C3/32
CPC分类号： C03C13/042 , C03B37/01211 , C03B37/0124 , C03B37/027 , C03B2201/82 , C03C3/325
摘要： A method of manufacturing an optical fiber preform, the method comprising: providing a substantially elongated core preform made out of a core fluorinated glass; providing a substantially elongated and substantially tubular cladding preform made out of a cladding fluorinated glass, the cladding preform defining a bore extending substantially longitudinally therethrough; inserting the core preform into the bore of the cladding preform; fusing the core preform and the cladding preform to each other to produce an intermediate preform; heating the intermediate preform up to a stretching temperature, the stretching temperature being such that the core and cladding fluorinated glasses both have a viscosity of between 10−7 and 10−9 Pa s at the stretching temperature; stretching the intermediate preform at the stretching temperature to produce a stretched intermediate preform; and cutting a section of the stretched intermediate preform. Typically, the stretching temperature is between a vitreous transition temperature and a crystallization temperature of the core and cladding glasses.
摘要翻译：一种制造光纤预制棒的方法，所述方法包括：提供由芯状氟化玻璃制成的大致细长的芯预制件; 提供由包层氟化玻璃制成的基本上细长且基本上管状的包层预制件，所述包层预制件限定基本上纵向延伸穿过其中的孔; 将芯预制件插入包层预制件的孔中; 将芯预制件和包层预制件彼此熔合以制造中间预制件; 将中间预制件加热到拉伸温度，拉伸温度使得芯和包层氟化玻璃在拉伸温度下的粘度都在10-7和10-9Pa之间; 在拉伸温度下拉伸中间预制件以制备拉伸的中间预制件; 并切割拉伸的中间预型件的一部分。通常，拉伸温度在玻璃化转变温度和芯和包层玻璃的结晶温度之间。

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