专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070218545A1 ANTIBODY CHIP, ANTIGEN MEASURING APPARATUS AND LIQUID DISCHARGING METHOD 审中-公开
标题翻译：抗体芯片，抗原测量装置和液体排出方法
公开(公告)号：US20070218545A1
公开(公告)日：2007-09-20
申请号：US11566857
申请日：2006-12-05
申请人： Ikuo Uematsu , Shingo Kasai , Kenichi Uchiyama , Tomohiro Kita , Kayoko Oomiya
发明人： Ikuo Uematsu , Shingo Kasai , Kenichi Uchiyama , Tomohiro Kita , Kayoko Oomiya
IPC分类号： C12M1/34
CPC分类号： G01N21/7703 , B01L3/021 , B01L3/508 , B01L3/5088 , B01L2300/0654 , B01L2300/0822 , B01L2300/0838 , B01L2400/0487 , G01N2021/7709 , G01N2021/7773 , G01N2021/7793
摘要： It is an object to provide an antibody chip and a light source measuring apparatus which are excellent in a reproducibility and a workability of a measurement and can easily be utilized. A light source measuring apparatus (1) includes, as a main structure, a concentration measuring device (2), an antibody chip (3) and a cell washing device (4). The concentration measuring device (2) serves to measure a concentration of an antigen in a specimen solution taken by the antibody chip (3) The cell washing device (4) has solution injecting means constituted by an injecting pump (44), an injecting tube (45), a first solution vessel (46), a second solution vessel (47) and a solution selecting valve (48) and solution discharging means constituted by a plurality of discharging pumps (51), a discharging tube (52), an intake end (52a) and the like. In a state in which a container cover (8) is opened, an inner part of a cell (39) of the antibody chip (3) having an antibody fixing layer formed on a main surface of a substrate (37) on a chip carrier (7) is washed to stabilize the antibody fixing layer without the solution remaining in the cell.
摘要翻译：本发明的目的是提供一种测量重现性和可加工性优异的抗体芯片和光源测量装置，并且可以容易地利用。作为主要结构的光源测量装置（1）包括浓度测定装置（2），抗体芯片（3）和细胞清洗装置（4）。浓度测定装置（2）用于测定由抗体芯片（3）取出的试样溶液中的抗原浓度。细胞洗涤装置（4）具有由注射泵（44），注射管（45），第一溶液容器（46），第二溶液容器（47）和溶液选择阀（48）以及由多个排出泵（51），排放管（52），排出管进气端（52a）等。在容器盖（8）打开的状态下，具有抗体固定层的抗体芯片（3）的电池（39）的内部部分形成在芯片载体上的基板（37）的主表面上（7）洗涤以稳定抗体固定层，而不将溶液保留在细胞中。

2. 发明申请

US20110180725A1 FLUOROMETRIC APPARATUS, FLUOROMETRIC METHOD, CONTAINER FOR FLUOROMETRY, AND METHOD OF MANUFACTURING CONTAINER FOR FLUOROMETRY 审中-公开
标题翻译：荧光测定装置，荧光法，荧光检测用容器及其制造方法
公开(公告)号：US20110180725A1
公开(公告)日：2011-07-28
申请号：US13080274
申请日：2011-04-05
申请人： Kenichi Uchiyama , Shingo Kasai , Ikuo Uematsu , Tomohiro Takase , Kayoko Oomiya , Ichiro Tono , Tetsuo Sekino , Seiichirou Ishioka , Takashi Kawamura
发明人： Kenichi Uchiyama , Shingo Kasai , Ikuo Uematsu , Tomohiro Takase , Kayoko Oomiya , Ichiro Tono , Tetsuo Sekino , Seiichirou Ishioka , Takashi Kawamura
IPC分类号： G01J1/58
CPC分类号： G01N21/6428 , G01N21/07 , G01N21/645
摘要： A fluorometric apparatus capable of configuring to have a small size and operability requiring a simple and easy operation of centrifuging a specimen in a container a rotation center of which is detachably supported by a rotation axis (not shown), exciting the specimen by means of an N2 laser apparatus and an excitation light irradiator for guiding the laser light emitted from the N2 laser apparatus, and receiving fluorescence having two types of wavelengths emitted from antibodies labeled with fluorescent dyes in the specimen in a region separate from the region in which the excitation light is radiated by a predetermined angle by using a photomultiplier tube, obtaining a ratio of light intensity for each wavelength, comparing the obtained ratio with a standard value, and estimating a target protein concentration.
摘要翻译：一种能够构造成具有小尺寸和可操作性的荧光测定装置，其需要简单且容易地将样品离心在容器中，旋转中心由旋转轴线（未示出）可拆卸地支撑，借助于 N2激光装置和激发光照射器，用于引导从N2激光装置发射的激光，并且在与激发光的区域分开的区域中接收在样品中的荧光染料标记的抗体的两种类型的波长的荧光通过使用光电倍增管照射预定角度，获得每个波长的光强比，将获得的比值与标准值进行比较，并估计目标蛋白质浓度。

3. 发明授权

US07498145B2 Concentration measuring method, concentration measuring kit, and sensor chip for use in the method 失效
标题翻译：浓度测定方法，浓度测定试剂盒，传感器芯片用于该方法
公开(公告)号：US07498145B2
公开(公告)日：2009-03-03
申请号：US11363094
申请日：2006-02-28
申请人： Kenichi Uchiyama , Kayoko Oomiya , Isao Kishimoto , Masami Hirata , Hideo Eto , Ichiro Tono , Ikuo Uematsu , Shingo Kasai , Tomohiro Takase , Tsutomu Honjoh , Masanori Sugitani
发明人： Kenichi Uchiyama , Kayoko Oomiya , Isao Kishimoto , Masami Hirata , Hideo Eto , Ichiro Tono , Ikuo Uematsu , Shingo Kasai , Tomohiro Takase , Tsutomu Honjoh , Masanori Sugitani
IPC分类号： G01N33/53 , G01N33/551 , G01N33/552 , G01N33/58
CPC分类号： G01N33/54373 , Y10S435/808 , Y10S436/805
摘要： The method for measuring the concentration of the measuring object uses a sensor chip comprising an optical waveguide layer and an antibody immobilized layer formed on the surface of the optical waveguide layer, which comprises immobilizing the measuring object and an enzyme-labeled antibody labeled with a labeling enzyme on the antibody immobilized layer of the sensor chip having an immobilized antibody, producing a color-developing and precipitating enzyme reaction product by allowing to react a coloring reagent with the labeling enzyme on the antibody immobilized layer to precipitate the enzyme reaction product on the antibody immobilized layer, allowing to totally reflect a light impinged on the sensor chip from the outside at an interface between the optical waveguide layer and the antibody immobilized layer, and observing to a physical value of the totally reflected light.
摘要翻译：用于测量对象浓度的方法使用包括形成在光波导层表面上的光波导层和抗体固定层的传感器芯片，其包括固定测量对象和用标记的酶标记的抗体酶在具有固定化抗体的传感器芯片的抗体固定化层上，通过使着色试剂与抗体固定化层上的标记酶反应，使酶反应产物沉淀在抗体上，产生显色和沉淀酶反应产物使得能够在光波导层和抗体固定化层之间的界面处从外部全面反射入射到传感器芯片上的光，并观察全反射光的物理值。

4. 发明申请

US20060194345A1 Concentration measuring method, concentration measuring kit, and sensor chip for use in the method 失效
公开(公告)号：US20060194345A1
公开(公告)日：2006-08-31
申请号：US11363094
申请日：2006-02-28
申请人： Kenichi Uchiyama , Kayoko Oomiya , Isao Kishimoto , Masami Hirata , Hideo Eto , Ichiro Tono , Ikuo Uematsu , Shingo Kasai , Tomohiro Takase , Tsutomu Honjoh , Masanori Sugitani
发明人： Kenichi Uchiyama , Kayoko Oomiya , Isao Kishimoto , Masami Hirata , Hideo Eto , Ichiro Tono , Ikuo Uematsu , Shingo Kasai , Tomohiro Takase , Tsutomu Honjoh , Masanori Sugitani
IPC分类号： G01N33/543 , C12M1/34
CPC分类号： G01N33/54373 , Y10S435/808 , Y10S436/805
摘要： The method for measuring the concentration of the measuring object uses a sensor chip comprising an optical waveguide layer and an antibody immobilized layer formed on the surface of the optical waveguide layer, which comprises immobilizing the measuring object and an enzyme-labeled antibody labeled with a labeling enzyme on the antibody immobilized layer of the sensor chip having an immobilized antibody, producing a color-developing and precipitating enzyme reaction product by allowing to react a coloring reagent with the labeling enzyme on the antibody immobilized layer to precipitate the enzyme reaction product on the antibody immobilized layer, allowing to totally reflect a light impinged on the sensor chip from the outside at an interface between the optical waveguide layer and the antibody immobilized layer, and observing to a physical value of the totally reflected light.

5. 发明申请

US20050084909A1 Antigen measuring device and method thereof, an antibody chip package and a pallet 审中-公开
标题翻译：抗原测量装置及其方法，抗体芯片封装和托盘
公开(公告)号：US20050084909A1
公开(公告)日：2005-04-21
申请号：US10928319
申请日：2004-08-30
申请人： Kenichi Uchiyama , Kayoko Oomiya , Isao Kishimoto , Masami Hirata , Hideo Eto , Ichiro Tono , Ikuo Uematsu
发明人： Kenichi Uchiyama , Kayoko Oomiya , Isao Kishimoto , Masami Hirata , Hideo Eto , Ichiro Tono , Ikuo Uematsu
IPC分类号： C12M1/34 , C12Q1/68 , G01N33/53 , G01N33/543 , G01N33/58
CPC分类号： G01N33/581 , G01N33/54306
摘要： An antigen measuring device has an antibody chip. The antibody chip has a substrate. A pair of gratings are formed on the substrate. An antibody-fixed layer surrounded by a wall is formed between the gratings. A light emitting element emits a light beam toward the first grating. A light receiving element receives the light beam which propagates through the substrate under the antibody-fixed layer and is outputfrom the second grating.
摘要翻译：抗原测定装置具有抗体芯片。抗体芯片具有底物。在基板上形成一对光栅。在光栅之间形成由壁包围的抗体固定层。发光元件朝向第一光栅发射光束。光接收元件接收在抗体固定层下传播通过衬底并从第二光栅输出的光束。

6. 发明申请

US20060063984A1 Optical waveguide type iontophoresis sensor chip and method for packaging sensor chip 失效
标题翻译：光波导型离子电渗传感器芯片及封装传感器芯片的方法
公开(公告)号：US20060063984A1
公开(公告)日：2006-03-23
申请号：US10899264
申请日：2004-07-26
申请人： Kenichi Uchiyama , Ikuo Uematsu , Kayoko Oomiya , Ichiro Tono , Hideo Eto , Isao Kishimoto , Naotada Okada , Masami Hirata
发明人： Kenichi Uchiyama , Ikuo Uematsu , Kayoko Oomiya , Ichiro Tono , Hideo Eto , Isao Kishimoto , Naotada Okada , Masami Hirata
IPC分类号： A61B5/00
CPC分类号： A61B5/14514 , A61B5/14532 , A61B5/1455
摘要： An optical waveguide type iontophoresis sensor chip has a substrate having a first hinged plate and a second hinged plate, an optical waveguide plate connected to the first hinged plate and positioned over a first opening delineated in the first hinged plate, and a gel layer fixed on the second hinged plate and covering a second opening delineated in the second hinged plate and configured to contact with the optical waveguide plate through the first opening in case that the substrate is folded.
摘要翻译：光波导型离子电渗传感器芯片具有：具有第一铰接板和第二铰接板的基板;连接到第一铰接板的光波导板，定位在第一铰接板中描绘的第一开口上;以及固定在所述第二铰接板并且覆盖在所述第二铰接板中描绘的第二开口，并且构造成在所述基板被折叠的情况下通过所述第一开口与所述光波导板接触。

7. 发明授权

US07410614B2 Optical waveguide type iontophoresis sensor chip and method for packaging sensor chip 失效
标题翻译：光波导型离子电渗传感器芯片及封装传感器芯片的方法
公开(公告)号：US07410614B2
公开(公告)日：2008-08-12
申请号：US10899264
申请日：2004-07-26
申请人： Kenichi Uchiyama , Ikuo Uematsu , Kayoko Oomiya , Ichiro Tono , Hideo Eto , Isao Kishimoto , Naotada Okada , Masami Hirata
发明人： Kenichi Uchiyama , Ikuo Uematsu , Kayoko Oomiya , Ichiro Tono , Hideo Eto , Isao Kishimoto , Naotada Okada , Masami Hirata
IPC分类号： G01N21/00 , G02B6/10
CPC分类号： A61B5/14514 , A61B5/14532 , A61B5/1455
摘要： An optical waveguide type iontophoresis sensor chip has a substrate having a first hinged plate and a second hinged plate, an optical waveguide plate connected to the first hinged plate and positioned over a first opening delineated in the first hinged plate, and a gel layer fixed on the second hinged plate and covering a second opening delineated in the second hinged plate and configured to contact with the optical waveguide plate through the first opening in case that the substrate is folded.
摘要翻译：光波导型离子电渗传感器芯片具有：具有第一铰接板和第二铰接板的基板;连接到第一铰接板的光波导板，定位在第一铰接板中描绘的第一开口上;以及固定在所述第二铰接板并且覆盖在所述第二铰接板中描绘的第二开口，并且构造成在所述基板被折叠的情况下通过所述第一开口与所述光波导板接触。

8. 发明授权

US07036457B2 Rodent housing rack 有权
标题翻译：啮齿动物机架
公开(公告)号：US07036457B2
公开(公告)日：2006-05-02
申请号：US10847451
申请日：2004-05-18
申请人： Kenichi Uchiyama , Shigeru Yanagihara , Shoji Iwamiya
发明人： Kenichi Uchiyama , Shigeru Yanagihara , Shoji Iwamiya
IPC分类号： A01K1/03
CPC分类号： A01K1/031
摘要： The invention provides a rodent housing rack that effectively draws the air inside the cages out through exhaust vents.The rodent housing rack comprises: a rack with multiple shelves 2 in which a plurality of cages 3 are arranged and stored, and where the shelves 2 are formed from shelf panels 4; cages 3 that are box-shaped containers having a rectangular-shaped opening that opens up the entire top surface; and an exhaust chamber located on the rear surface of the shelves 2 and that connects all of the shelves 2; and wherein negative pressure occurs inside the shelves 2 and causes air to flow in one-way from the front of the shelves 2 toward the rear; and wherein the space between the opening surface on the top of the cage 3 and the bottom surface of the shelf panel 4 above it is closed off by hanger partitions 5 that close off the top on the left and right sides of the cage and a back panel that comes in contact with the rear of the cage, such that only the front side of the space is open; and exhaust vents 9 are formed in the back panel such that the space above the cage is connected to the exhaust chamber through the vents.
摘要翻译：本发明提供了一种啮齿动物机架，其有效地通过排气口将笼内的空气抽出。啮齿动物架架包括：具有多个搁架2的机架，多个搁架3布置和存放在其中，架子2由搁板4形成; 笼3是具有开口整个顶表面的矩形开口的箱形容器; 以及位于搁架2的后表面上并连接所有搁架2的排气室; 并且其中在搁架2内部发生负压，并使空气从架子2的前部朝向后方单向流动; 并且其中，保持架3的顶部上的开口表面与其上方的搁板4的底表面之间的空间被靠在保持架的左侧和右侧的顶部的悬挂器隔板5封闭，与保持架的后部接触的面板，使得只有空间的前侧是敞开的; 并且排气通风口9形成在后面板中，使得保持架上方的空间通过通风口连接到排气室。

9. 发明授权

US06866718B2 Applicator for applying material to wires of a wire group 失效
标题翻译：用于将材料施加到电线组的电线上的涂敷器
公开(公告)号：US06866718B2
公开(公告)日：2005-03-15
申请号：US10272864
申请日：2002-10-16
申请人： Hisato Chujo , Koshi Abe , Hirotake Baba , Kenichi Uchiyama
发明人： Hisato Chujo , Koshi Abe , Hirotake Baba , Kenichi Uchiyama
IPC分类号： H05K7/00 , H01B7/282 , H01B13/012 , H01B13/32 , H02G3/22 , H02G3/30 , B05B3/00 , H01B7/28
CPC分类号： H01B13/32 , H01B13/01263 , Y02A30/14 , Y10S118/22 , Y10T29/49194
摘要： A sealant applicator 1 is provided for applying a waterproofing treatment to a wire assembly, a plurality of wires are aligned in a line according to their diameters in a holder 4 provided on a wire laying board 3. Positioning members 21 of a main unit 2 are fitted to the holder 4. A pair of nozzles 22 are opposed to each other at the opposite sides of the aligned wires, and is caused to discharge a specified amount of the sealant by a feeding mechanism 26 while being moved in a wire alignment direction by a moving mechanism 27 and being brought closer to the wires by a relatively moving mechanism 25. This enables a variation of clearances between the wires and the nozzles to be reduced and the sealant to be uniformly applied.
摘要翻译：设置密封剂涂布器1，用于对线组件进行防水处理，根据设置在敷线板3上的保持件4中的直径将多根线对齐。主单元2的定位构件21为一对喷嘴22在对准的线的相对侧彼此相对，并且通过馈送机构26在线对准方向上移动时排出指定量的密封剂，同时通过移动机构27并且通过相对移动的机构25而更靠近线。这使得能够减少电线和喷嘴之间的间隙的变化并且均匀地施加密封剂。

10. 发明申请

US20110104009A1 CLINICAL EXAMINATION DISK, DISK PACK, AND CLINICAL EXAMINATION DEVICE 审中-公开
标题翻译：临床检查盘，盘盒和临床检查装置
公开(公告)号：US20110104009A1
公开(公告)日：2011-05-05
申请号：US12986846
申请日：2011-01-07
申请人： Toshimi Kawamura , Seiichirou Ishioka , Masaki Tonari , Takashi Kawamura , Akira Nakajima , Tetsuo Sekino , Kyoichi Iwahashi , Kenichi Uchiyama , Tomohiro Takase , Isao Nawata
发明人： Toshimi Kawamura , Seiichirou Ishioka , Masaki Tonari , Takashi Kawamura , Akira Nakajima , Tetsuo Sekino , Kyoichi Iwahashi , Kenichi Uchiyama , Tomohiro Takase , Isao Nawata
IPC分类号： G01N33/00
CPC分类号： G01N33/491 , B01L3/5027 , B01L2200/16 , B01L2300/0803 , B01L2300/0816 , B01L2300/0887 , B01L2300/1827 , B01L2400/0406 , B01L2400/0409 , B01L2400/0677 , G01N35/00069
摘要： A clinical examination disk according to the invention includes a disk body in a disk form, and at least one cell formed in the disk body, wherein the cell comprises a specimen reservoir formed in the disk body and having a specimen injecting port, a reaction tank formed in the disk body so as to position nearer to the outer circumference of the body than a position of the specimen reservoir, and holding a reagent which is reactive with the specimen and is beforehand gelatinized, a first narrow tube formed in the disk body, and communicating to the specimen reservoir and the reaction tank, and a second narrow tube formed in the disk body, and having one end connected to the reaction tank and the other end made open.
摘要翻译：根据本发明的临床检查盘包括盘形的盘体和形成在盘体中的至少一个单元，其中所述单元包括形成在所述盘体中的样本储存器，并且具有样本注入口，反应罐形成在所述盘体上，以比所述检体容器的位置更靠近所述本体的外周的位置，并且保持与所述检体反应的试剂，并预先糊化，形成在所述盘体上的第一窄管，并且与样品容器和反应槽连通，以及形成在盘体中的第二窄管，其一端连接到反应罐，另一端打开。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式