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1. 发明授权

US5236903A Polypeptide comprising repeated cell-adhesive core sequences 失效
标题翻译：多肽包含重复的细胞粘附核心序列
公开(公告)号：US5236903A
公开(公告)日：1993-08-17
申请号：US912323
申请日：1992-07-13
申请人： Ikuo Saiki , Norio Nishi , Ichiro Azuma , Seiichi Tokura
发明人： Ikuo Saiki , Norio Nishi , Ichiro Azuma , Seiichi Tokura
IPC分类号： A61K38/00 , C07K14/47 , C07K14/78
CPC分类号： C07K14/78 , C07K14/47 , A61K38/00
摘要： A polypeptide comprising repeated amino acid sequences of a cell-adhesive protein represented by the formula:(Arg-Gly-Asp)n or (Tyr-Ile-Gly-Ser-Arg)nwherein n is a number ranging from 2 to 20; or a pharmaceutical acceptable salt thereof, which is valuable as an antimetastatic agent for cancer.
摘要翻译：一种多肽，其包含由式（Arg-Gly-Asp）n或（Tyr-Ile-Gly-Ser-Arg）n表示的细胞粘附蛋白的重复氨基酸序列，其中n为2至20的数; 或其药学上可接受的盐，其作为癌症的抗转移剂是有价值的。

2. 发明授权

US5183804A Polypeptide comprising repeated cell-adhesive core sequences 失效
标题翻译：包含重复的细胞粘附核酸序列的多肽
公开(公告)号：US5183804A
公开(公告)日：1993-02-02
申请号：US370182
申请日：1989-06-23
申请人： Ikuo Saiki , Norio Nishi , Ichiro Azuma , Seiichi Tokura
发明人： Ikuo Saiki , Norio Nishi , Ichiro Azuma , Seiichi Tokura
IPC分类号： A61K38/00 , A61P35/00 , C07K7/06 , C07K7/08 , C07K14/00 , C07K14/47 , C07K14/78 , C08G69/00
CPC分类号： C07K14/78 , C07K14/47 , A61K38/00 , Y02P20/55
摘要： A polypeptide comprising repeated amino acid sequences of a cell-adhesive protein represented by the formula:(Arg--Gly--Asp)nor(Tyr--Ile--Gly--Ser--Arg)nwherein n is a number ranging from 2 to 20; or a pharmaceutical acceptable salt thereof, which is valuable as an antimetastatic agent for cancer.

3. 发明授权

US4392916A Paper-making process with regenerated chitin fibers 失效
标题翻译：造纸过程与再生几丁质纤维
公开(公告)号：US4392916A
公开(公告)日：1983-07-12
申请号：US351636
申请日：1982-02-23
申请人： Masashi Nishiyama , Yoshinari Kobayashi , Seiichi Tokura , Norio Nishi
发明人： Masashi Nishiyama , Yoshinari Kobayashi , Seiichi Tokura , Norio Nishi
IPC分类号： D01F9/00 , A61L15/28 , D21H13/10 , D21H5/12
CPC分类号： D21H5/1227 , A61L15/28 , D21H13/30
摘要： The invention provides a novel method for making paper of regenerated chious fibers without the use of any binder materials. By virtue of the inherent physiological inertness of the chitinous fibers and the absence of any binder materials, the paper obtained by the inventive method is advantageously used in medical treatment in contact with living body tissues. The principle of the method is that the chitinous fibers prepared by a wet spinning process are never brought into a dry condition or always kept wet with water down to the step of sheet making so that the self-bonding power of the fibers by the hydrogen bonding is never decreased and a chitinous paper with sufficient strengths can be prepared without a binder material. Alternatively, once dried chitinous fibers can be treated with a hydrogen-bond forming agent, e.g. urea, so that the sheet making is equally successful without the use of a binder material.
摘要翻译：本发明提供了不使用任何粘合剂材料制造再生几丁质纤维纸的新方法。由于几丁质纤维的固有生理惰性和不存在任何粘合剂材料，通过本发明方法获得的纸有利地用于与生物体组织接触的医疗中。该方法的原理是通过湿纺丝方法制备的壳多糖纤维不会进入干燥状态，或者始终保持用水润湿直至制片步骤，使得通过氢键的纤维的自粘合力不会减少，并且可以在没有粘合剂材料的情况下制备具有足够强度的几丁质纸。或者，一旦干燥的几丁质纤维可以用氢键形成剂，例如，尿素，使得片材制造同样成功，而不使用粘合剂材料。

4. 发明授权

US08674163B2 DNA hybrids and environment cleaning system employing DNA hybrids 失效
标题翻译：使用DNA杂交体的DNA杂种和环境清洁系统
公开(公告)号：US08674163B2
公开(公告)日：2014-03-18
申请号：US11653233
申请日：2007-01-16
申请人： Zuyi Zhang , Teigo Sakakibara , Yoshinori Kotani , Norio Nishi
发明人： Zuyi Zhang , Teigo Sakakibara , Yoshinori Kotani , Norio Nishi
IPC分类号： A62D3/33 , A62D3/00 , C07H21/02 , C12Q1/68 , C12M1/34 , G01N33/553 , G01N33/552
CPC分类号： B01J20/28061 , B01J20/06 , B01J20/08 , B01J20/103 , B01J20/3078 , B01J20/3204 , B01J20/3274 , B01J20/3293 , B01J20/3297 , B01J2220/42 , B01J2220/58 , C02F1/286 , C02F1/288 , C07H21/00 , C12Q1/6834
摘要： A DNA hybrid which comprises a porous oxide matrix and DNA immobilized thereon, and is useful for environmental clean-up, where the hybrid is prepared by removing a dispersion medium from a dispersion of colloidal oxide and DNA.
摘要翻译：一种DNA杂交体，其包含多孔氧化物基质和固定在其上的DNA，并且可用于环境清洁，其中通过从胶体氧化物和DNA的分散体中除去分散介质制备杂交体。

5. 发明申请

US20070135672A1 DNA hybrids and environment cleaning system employing DNA hybrids 失效
标题翻译：使用DNA杂交体的DNA杂种和环境清洁系统
公开(公告)号：US20070135672A1
公开(公告)日：2007-06-14
申请号：US11653233
申请日：2007-01-16
申请人： Zuyi Zhang , Teigo Sakakibara , Yoshinori Kotani , Norio Nishi
发明人： Zuyi Zhang , Teigo Sakakibara , Yoshinori Kotani , Norio Nishi
IPC分类号： A62D3/02 , A62D101/20 , C07H21/04
CPC分类号： B01J20/28061 , B01J20/06 , B01J20/08 , B01J20/103 , B01J20/3078 , B01J20/3204 , B01J20/3274 , B01J20/3293 , B01J20/3297 , B01J2220/42 , B01J2220/58 , C02F1/286 , C02F1/288 , C07H21/00 , C12Q1/6834
摘要： A DNA hybrid which comprises a porous oxide matrix and DNA immobilized thereon, and is useful for environmental clean-up, where the hybrid is prepared by removing a dispersion medium from a dispersion of colloidal oxide and DNA.
摘要翻译：一种DNA杂交体，其包含多孔氧化物基质和固定在其上的DNA，并且可用于环境清洁，其中通过从胶体氧化物和DNA的分散体中除去分散介质制备杂交体。

6. 发明申请

US20050170402A1 Method of separating substance from liquid 审中-公开
标题翻译：物质与液体分离的方法
公开(公告)号：US20050170402A1
公开(公告)日：2005-08-04
申请号：US11045284
申请日：2005-01-31
申请人： Zuyi Zhang , Teigo Sakakibara , Yoshinori Kotani , Toshiya Yuasa , Norio Nishi
发明人： Zuyi Zhang , Teigo Sakakibara , Yoshinori Kotani , Toshiya Yuasa , Norio Nishi
IPC分类号： B01D15/00 , B01J20/24 , B01J20/32 , C02F1/28 , C12Q1/68 , C12M1/34
CPC分类号： C02F1/286 , B01D15/00 , B01J20/24 , B01J20/3204 , B01J20/321 , B01J20/3212 , B01J20/3274 , B01J20/3282 , C02F1/285 , C02F1/288 , C02F2101/363 , C02F2101/366 , C12Q1/6837
摘要： A liquid containing a separation target substance is brought into contact with a double helix DNA-holding phase to have the separation target substance held by the double helix DNA-holding phase, which is then removed from the liquid. On this occasion, the contact of the double helix DNA with the separation target substance is performed in an aqueous medium having a salt concentration of 0.02 mass % or more.
摘要翻译：使含有分离对象物质的液体与双螺旋DNA保持相接触，使分离对象物质被双螺旋DNA保持相保持，然后从液体中除去。此时，双重螺旋DNA与分离对象物质的接触在盐浓度为0.02质量％以上的水性介质中进行。

7. 发明授权

US09492889B2 Laser processing machine 有权
标题翻译：激光加工机
公开(公告)号：US09492889B2
公开(公告)日：2016-11-15
申请号：US13814227
申请日：2012-07-26
申请人： Masami Suzuki , Norio Nishi , Junichi Matsumoto , Nobutaka Yoneyama , Satoshi Tokuoka , Etsushi Kato
发明人： Masami Suzuki , Norio Nishi , Junichi Matsumoto , Nobutaka Yoneyama , Satoshi Tokuoka , Etsushi Kato
IPC分类号： B23K26/02 , B23K26/04 , B23K26/067 , B23K26/03 , B23K26/06 , B23K26/08
CPC分类号： B23K26/04 , B23K26/032 , B23K26/042 , B23K26/0643 , B23K26/0665 , B23K26/067 , B23K26/082 , B23K26/0853
摘要： A processing machine includes mirrors and to reflect a beam L oscillated from a laser oscillator to a predetermined surface on which a workpiece is arranged, optical axis operating mechanisms and to position an optical axis of the beam L at a desired target irradiation position by changing directions of the mirrors and, a camera sensor to capture an image of the target irradiation position and its periphery reflected in the mirror, and an error calibration mechanism to detect an error between the target irradiation position instructed to the optical axis operating mechanisms and an actual position of the optical axis of the beam L in the predetermined surface by referring to the image captured by the camera sensor. A correction amount to the optical axis operating mechanisms and is determined based on the error to irradiate the target irradiation position with the beam L during processing.
摘要翻译：加工机器包括反射镜并将从激光振荡器振荡的光束L反射到其上布置工件的预定表面，光轴操作机构，并且通过改变方向将光束L的光轴定位在期望的目标照射位置以及用于拍摄目标照射位置的图像及其反射镜中的周边的图像的摄像机传感器，以及用于检测指示到光轴操作机构的目标照射位置与实际位置之间的误差的误差校准机构通过参照由照相机传感器拍摄的图像，在预定表面中的光束L的光轴。对光轴操作机构的校正量，并且基于在处理期间用光束L照射目标照射位置的误差来确定。

8. 发明申请

US20130186871A1 LASER PROCESSING MACHINE 有权
标题翻译：激光加工机
公开(公告)号：US20130186871A1
公开(公告)日：2013-07-25
申请号：US13814227
申请日：2012-07-26
申请人： Masami Suzuki , Norio Nishi , Junichi Matsumoto , Nobutaka Yoneyama , Satoshi Tokuoka , Etsushi Kato
发明人： Masami Suzuki , Norio Nishi , Junichi Matsumoto , Nobutaka Yoneyama , Satoshi Tokuoka , Etsushi Kato
IPC分类号： B23K26/04 , B23K26/067
CPC分类号： B23K26/04 , B23K26/032 , B23K26/042 , B23K26/0643 , B23K26/0665 , B23K26/067 , B23K26/082 , B23K26/0853
摘要： A processing machine includes mirrors and to reflect a beam L oscillated from a laser oscillator to a predetermined surface on which a workpiece is arranged, optical axis operating mechanisms and to position an optical axis of the beam L at a desired target irradiation position by changing directions of the mirrors and, a camera sensor to capture an image of the target irradiation position and its periphery reflected in the mirror, and an error calibration mechanism to detect an error between the target irradiation position instructed to the optical axis operating mechanisms and an actual position of the optical axis of the beam L in the predetermined surface by referring to the image captured by the camera sensor. A correction amount to the optical axis operating mechanisms and is determined based on the error to irradiate the target irradiation position with the beam L during processing.
摘要翻译：加工机器包括反射镜并将从激光振荡器振荡的光束L反射到其上布置工件的预定表面，光轴操作机构，并且通过改变方向将光束L的光轴定位在期望的目标照射位置以及用于拍摄目标照射位置的图像及其反射镜中的周边的图像的摄像机传感器，以及用于检测指示到光轴操作机构的目标照射位置与实际位置之间的误差的误差校准机构通过参照由照相机传感器拍摄的图像，在预定表面中的光束L的光轴。对光轴操作机构的校正量，并且基于在处理期间用光束L照射目标照射位置的误差来确定。

9. 发明申请

US20060110816A1 Method of concentrating and removing harmful substance using double-stranded dna and adsorbent and apparatus therefor 审中-公开
标题翻译：使用双链dna和吸附剂浓缩和去除有害物质的方法及其设备
公开(公告)号：US20060110816A1
公开(公告)日：2006-05-25
申请号：US10542430
申请日：2003-11-17
申请人： Xiang Liu , Masaji Matsunaga , Norio Nishi
发明人： Xiang Liu , Masaji Matsunaga , Norio Nishi
IPC分类号： B09C1/10
CPC分类号： B01D61/243 , A23C7/04 , B01D15/00 , B01D61/28 , B01D63/02 , B01D2313/40 , B01J20/24 , B01J20/2805 , C02F1/286 , C02F1/288 , C02F1/44 , C02F2101/36 , C02F2101/366 , C02F2303/16
摘要： There is provided a method of removing harmful substance characterized by comprising contacting a harmful substance-containing liquid to be treated with a double-stranded DNA, adsorbing the harmful substance onto the double-stranded DNA through intercalation, and separating it. The method is particularly useful for removing dioxins, and can be carried out by contacting a liquid to be treated with an adsorbent comprising a double-stranded DNA or a solution containing a double-stranded DNA enclosed in a container or a bag made of a membrane that is permeable for the harmful substance but is not permeable for the double-stranded DNA.
摘要翻译：提供了除去有害物质的方法，其特征在于包括使待处理的有害物质的液体与双链DNA接触，通过插入将有害物质吸附到双链DNA上，并将其分离。该方法特别可用于除去二恶英，并且可以通过使待处理的液体与包含双链DNA的吸附剂或包含在容器中的双链DNA的溶液或由膜制成的袋接触来进行对于有害物质是可渗透的，但对双链DNA不可渗透。

10. 发明申请

US20090272392A1 Cigarette filter capable of removing harmful substance 审中-公开
标题翻译：能去除有害物质的香烟过滤器
公开(公告)号：US20090272392A1
公开(公告)日：2009-11-05
申请号：US11919217
申请日：2005-04-28
申请人： Xiang Dong Liu , Masaji Matsunaga , Norio Nishi
发明人： Xiang Dong Liu , Masaji Matsunaga , Norio Nishi
IPC分类号： A24D3/04
CPC分类号： A24D3/10 , A24D3/14
摘要： [PROBLEMS] To provide a cigarette filter that does not impair the distinctive flavor of a cigarette and the air permeability of filter while smoking, and at the same time, can more effectively remove harmful substances such as a pyrene that is generated from the cigarette.[MEANS FOR SOLVING PROBLEMS] The cigarette filter comprising a filter fiber bundle body which cigarette smoke passes through; a fine powder with a high surface area ratio that are mixed and scattered in the filter fiber bundle body; and a double-stranded DNA molecule attached to the outer surface of the fine powder with a high surface area ratio, characterized in that harmful substances such as benzo[a]pyrene contained in the cigarette smoke can be removed by intercalation into the double-stranded DNA molecule.
摘要翻译：本发明提供一种香烟过滤嘴，其不会损害香烟的独特风味，同时吸烟时的过滤器的透气性，同时可以更有效地除去由香烟产生的芘等有害物质。解决问题的手段香烟过滤嘴包括香烟烟雾通过的过滤纤维束体; 在过滤纤维束体中混合分散有高表面积比的细粉末; 和具有高表面积比的细粉末外表面附着的双链DNA分子，其特征在于，通过插入双链中除去香烟烟雾中含有的苯并[a]芘等有害物质 DNA分子。

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