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    • 1. 发明授权
    • Active matrix display device
    • 主动矩阵显示装置
    • US08284364B2
    • 2012-10-09
    • US12765105
    • 2010-04-22
    • Ichiro YamakawaKazuhiko HorikoshiNaotoshi AkamatsuJun GotohHiroaki Asuma
    • Ichiro YamakawaKazuhiko HorikoshiNaotoshi AkamatsuJun GotohHiroaki Asuma
    • G02F1/1333
    • G02F1/136286G02F1/136213G02F1/136227
    • Provided is a technology for preventing current leak of a charge holding capacitor which constitutes a pixel of a display device so as to prevent deterioration of display image quality of the display device. The display device includes a first contact hole connecting a first wiring layer and a second wiring layer which is formed over the first wiring layer, a second contact hole connecting the second wiring layer and a third wiring layer which is formed over the second wiring layer, and an electrode layer formed between the plurality of insulating films disposed between the second wiring layer and the third wiring layer, wherein at a position in a substrate surface direction, a distance between a electrode layer and the second contact hole is larger than a distance between the electrode layer and the first contact hole.
    • 提供了一种用于防止构成显示装置的像素的电荷保持电容器的电流泄漏的技术,以防止显示装置的显示图像质量的劣化。 该显示装置包括连接第一布线层和形成在第一布线层上的第二布线层的第一接触孔,连接第二布线层的第二接触孔和形成在第二布线层上的第三布线层, 以及形成在所述第二布线层和所述第三布线层之间的所述多个绝缘膜之间的电极层,其中,在基板表面方向的位置处,电极层与所述第二接触孔之间的距离大于 电极层和第一接触孔。
    • 2. 发明授权
    • Process for producing drug-containing microspheres by oil-in-water
evaporation process
    • 通过水包油蒸发法生产含药微球的方法
    • US5980947A
    • 1999-11-09
    • US352188
    • 1994-12-01
    • Ichiro YamakawaRyoichi MachidaSumio Watanabe
    • Ichiro YamakawaRyoichi MachidaSumio Watanabe
    • A61K9/16A61K9/50B01J13/12A61K9/14
    • A61K9/1694A61K9/1617A61K9/1647
    • Formation of a drug into microspheres by an oil-on-water solvent evaporation process in which a mixed solvent of at least one water-insoluble solvent and at least one water-miscible solvent is used as a solvent of an oil phase. A fatty acid or a salt thereof or at least one glycerin fatty acid ester and/or at least one propylene glycol fatty acid ester are added to the mixed solvent. The oil phase may also comprise the mixed solvent; a fatty acid or a salt thereof; and at least one glycerin fatty acid ester and/or at least one propylene glycol fatty acid ester. This oil phase is mixed and emulsified with an aqueous phase to form an oil-in-water emulsion. The emulsion with a drug contained therein is then subjected to an oil-in water solvent evaporation to produce the microspheres. The resulting drug-containing microspheres contain the drug at a high concentration and slowly release from the initial stage after administration.
    • 通过油包水溶剂蒸发方法将药物形成为微球,其中使用至少一种水不溶性溶剂和至少一种与水相混溶的溶剂的混合溶剂作为油相的溶剂。 向混合溶剂中加入脂肪酸或其盐或至少一种甘油脂肪酸酯和/或至少一种丙二醇脂肪酸酯。 油相也可以包含混合溶剂; 脂肪酸或其盐; 和至少一种甘油脂肪酸酯和/或至少一种丙二醇脂肪酸酯。 将该油相与水相混合并乳化以形成水包油乳液。 然后将其中含有药物的乳液进行油包水溶剂蒸发以产生微球体。 所得含药微球含有高浓度的药物,并在给药后从初始阶段缓慢释放。