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1. 发明授权

US07257193B2 X-ray source assembly having enhanced output stability using tube power adjustments and remote calibration 有权
标题翻译： X射线源组件使用管功率调节和远程校准具有增强的输出稳定性
公开(公告)号：US07257193B2
公开(公告)日：2007-08-14
申请号：US11347668
申请日：2006-02-03
申请人： Ian Radley , Michael D. Moore , Mark Fitzgerald
发明人： Ian Radley , Michael D. Moore , Mark Fitzgerald
IPC分类号： H05G1/26
CPC分类号： H05G1/36 , G21K2201/06 , H01J2235/1291 , H05G1/025
摘要： An x-ray source assembly includes an anode having a spot upon which electrons impinge based on power level supplied to the assembly, and an optic coupled to receive divergent x-rays generated at the spot and transmit output x-rays from the assembly. A control system is provided for maintaining intensity of the output x-rays dynamically during operation of the x-ray source assembly, notwithstanding a change in at least one operating condition of the x-ray source assembly, by changing the power level supplied to the assembly. The control system may include at least one actuator for effecting the change in the power level supplied to the assembly, by, e.g., controlling a power supply associated with the assembly. The control system may also change the temperature and/or the position of the anode to maintain the output intensity.
摘要翻译： x射线源组件包括阳极，阳极基于提供给组件的功率电平而撞击电子的点，以及光耦合以接收在该点处产生的发散的x射线，并从组件传输输出x射线。提供了一种控制系统，用于在x射线源组件的操作期间动态地保持输出x射线的强度，尽管通过改变提供给X射线源组件的功率电平，尽管x射线源组件的至少一个操作状态发生变化部件。控制系统可以包括至少一个致动器，用于通过例如控制与组件相关联的电源来实现提供给组件的功率水平的变化。控制系统还可以改变阳极的温度和/或位置以维持输出强度。

2. 发明申请

US20060193438A1 X-ray source assembly having enhanced output stability using tube power adjustments and remote calibration 有权
标题翻译： X射线源组件使用管功率调节和远程校准具有增强的输出稳定性
公开(公告)号：US20060193438A1
公开(公告)日：2006-08-31
申请号：US11347668
申请日：2006-02-03
申请人： Ian Radley , Michael Moore , Mark Fitzgerald
发明人： Ian Radley , Michael Moore , Mark Fitzgerald
IPC分类号： H05G2/00 , G21G4/00 , H01J35/00
CPC分类号： H05G1/36 , G21K2201/06 , H01J2235/1291 , H05G1/025
摘要： An x-ray source assembly includes an anode having a spot upon which electrons impinge based on power level supplied to the assembly, and an optic coupled to receive divergent x-rays generated at the spot and transmit output x-rays from the assembly. A control system is provided for maintaining intensity of the output x-rays dynamically during operation of the x-ray source assembly, notwithstanding a change in at least one operating condition of the x-ray source assembly, by changing the power level supplied to the assembly. The control system may include at least one actuator for effecting the change in the power level supplied to the assembly, by, e.g., controlling a power supply associated with the assembly. The control system may also change the temperature and/or the position of the anode to maintain the output intensity.
摘要翻译： x射线源组件包括阳极，阳极基于提供给组件的功率电平而撞击电子的点，以及光耦合以接收在该点处产生的发散的x射线，并从组件传输输出x射线。提供了一种控制系统，用于在x射线源组件的操作期间动态地保持输出x射线的强度，尽管通过改变提供给X射线源组件的功率电平，尽管x射线源组件的至少一个操作状态发生变化部件。控制系统可以包括至少一个致动器，用于通过例如控制与组件相关联的电源来实现提供给组件的功率水平的变化。控制系统还可以改变阳极的温度和/或位置以维持输出强度。

3. 发明授权

US07550474B2 Substituted phenyl acetamides and their use as protease inhibitors 有权
标题翻译：取代苯乙酰胺及其作为蛋白酶抑制剂的用途
公开(公告)号：US07550474B2
公开(公告)日：2009-06-23
申请号：US10816544
申请日：2004-04-01
申请人： Kevin D. Kreutter , Lily Lee , Tianbao Lu , Venkatraman Mohan , Sharmila Patel , Hui Huang , Guozhang Xu , Mark Fitzgerald
发明人： Kevin D. Kreutter , Lily Lee , Tianbao Lu , Venkatraman Mohan , Sharmila Patel , Hui Huang , Guozhang Xu , Mark Fitzgerald
IPC分类号： A61K31/435 , C07D221/02 , C07D335/00 , C07D309/00 , C07C321/00
CPC分类号： C07D213/73 , C07C279/00 , C07C291/04 , C07D213/26 , C07D213/89 , C07D215/12 , C07D413/12 , C07D487/04
摘要： Phenyl acetamide compounds are described, including compounds of Formula I: or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R3-R6, R11, B, Y and W are set forth in the specification. The compounds of the invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as thrombin and factor Xa. Compositions for inhibiting loss of blood platelets, inhibiting formation of blood platelet aggregates, inhibiting formation of fibrin, inhibiting thrombus formation, and inhibiting embolus formation are described. Other uses of compounds of the invention are as anticoagulants either embedded in or physically linked to materials used in the manufacture of devices used in blood collection, blood circulation, and blood storage, such as catheters, blood dialysis machines, blood collection syringes and tubes, blood lines and stents. Additionally, the compounds can be detectably labeled and employed for in vivo imaging of thrombi.
摘要翻译：描述了苯基乙酰胺化合物，包括式I化合物或其溶剂合物，水合物或其药学上可接受的盐; 其中R3-R6，R11，B，Y和W在说明书中列出。本发明的化合物是蛋白酶的有效抑制剂，特别是胰蛋白酶样的丝氨酸蛋白酶，如凝血酶和因子Xa。描述了抑制血小板损失，抑制血小板聚集体形成，抑制纤维蛋白形成，抑制血栓形成和抑制栓塞形成的组合物。本发明化合物的其它用途是作为凝血剂或者物理上连接于用于血液收集，血液循环和血液储存（例如导管，血液透析机，采血注射器和管）中使用的装置的制造中使用的材料的抗凝剂，血线和支架。另外，化合物可以被可检测地标记并用于血栓的体内成像。

4. 发明授权

US4642137A Mineral binder and compositions employing the same 失效
标题翻译：矿物粘合剂和使用其的组合物
公开(公告)号：US4642137A
公开(公告)日：1987-02-10
申请号：US708689
申请日：1985-03-06
申请人： Richard F. Heitzmann , Mark Fitzgerald , James L. Sawyer
发明人： Richard F. Heitzmann , Mark Fitzgerald , James L. Sawyer
IPC分类号： C04B7/345 , C04B12/00 , C04B22/00 , C04B28/00 , C04B28/04 , C04B28/26 , C04B7/00
CPC分类号： C04B28/00 , C04B12/005 , C04B28/006 , C04B28/04 , C04B28/26 , Y02P40/165 , Y02W30/92 , Y02W30/94
摘要： A binder composition for Portland cement is disclosed, said composition including 100 parts by weight metakaolin and, based upon said metakaolin, from 20 to 70 parts by weight slag; from 85 to 130 parts by weight of at least 1 material selected from the class consisting of fly ash, calcined shale, and calcined clay; from 70 to 215 parts by weight finely divided silica, preferably amorphous silica; and from 55 to 145 parts by weight of a mixture of potassium silicate and potassium hydroxide, wherein at least 55 parts by weight is potassium silicate. The binder composition can be mixed with Portland cement or with a combination of Portland cement and fly ash to provide a composition curable to a material having a high early strength and a high ultimate strength.
摘要翻译：公开了一种用于波特兰水泥的粘合剂组合物，所述组合物包含100重量份的偏高岭土和基于所述偏高岭土的20至70重量份的渣; 85至130重量份的选自飞灰，煅烧页岩和煅烧粘土的至少1种材料; 70至215重量份的细分二氧化硅，优选无定形二氧化硅; 和55至145重量份的硅酸钾和氢氧化钾的混合物，其中至少55重量份是硅酸钾。粘合剂组合物可与波特兰水泥或波特兰水泥和飞灰的组合混合，以提供具有高强度和高极限强度的材料可固化的组合物。

5. 发明授权

US4640715A Mineral binder and compositions employing the same 失效
标题翻译：矿物粘合剂和使用其的组合物
公开(公告)号：US4640715A
公开(公告)日：1987-02-03
申请号：US708732
申请日：1985-03-06
申请人： Richard E. Heitzmann , Mark Fitzgerald , James L. Sawyer
发明人： Richard E. Heitzmann , Mark Fitzgerald , James L. Sawyer
IPC分类号： C04B7/345 , C04B7/13 , C04B28/00 , C04B28/04 , C04B7/00
CPC分类号： C04B28/04 , C04B28/006 , Y02P40/165 , Y02W30/92 , Y02W30/94
摘要： A dry, mineral binder composition is disclosed having from 6 to 25 parts by weight metakaolin, 3 to 30 parts by weight dry potassium hydroxide, 0 to 18 parts by weight slag, 0 to 60 parts by weight of a material selected from the class consisting of fly ash, calcined shale, and calcined clay, and from 1 to 150 parts, by weight, of a finely divided silica, preferably an amorphous silica. The binder is particularly useful in combination with Portland cement for forming concrete compositions.
摘要翻译：公开了一种干燥的矿物粘合剂组合物，其具有6至25重量份偏高岭土，3至30重量份干燥氢氧化钾，0至18重量份矿渣，0至60重量份的选自以下的材料：的飞灰，煅烧页岩和煅烧的粘土，以及1至150重量份的细碎二氧化硅，优选无定形二氧化硅。粘合剂特别适用于与波特兰水泥组合以形成混凝土组合物。

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